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Sophie G B Neech, Helen Scott, Helena M Priest, Eleanor J Bradley, Alison E Tweed
INTRODUCTION: Despite guidance promoting user involvement, meaningful involvement continues to be debated within services. To effectively implement involvement, it is important to acknowledge why users devote time to such activities. AIM: This study explores user representatives' experiences of involvement, including motivations and personal benefits. METHOD: Thirteen user representatives involved in activities such as staff training and interviews were recruited from a UK National Health Service mental health Trust during 2015...
May 12, 2018: Journal of Psychiatric and Mental Health Nursing
Carla R Schubert, Adam J Paulsen, David M Nondahl, Dayna S Dalton, Mary E Fischer, Barbara E K Klein, Ronald Klein, Ted S Tweed, Karen J Cruickshanks
Importance: Hearing impairment (HI) is one of the most common conditions affecting older adults. Identification of factors associated with the development of HI may lead to ways to reduce the incidence of this condition. Objective: To investigate the association between cystatin C, both as an independent biomarker and as a marker of kidney function, and the 20-year incidence of HI. Design, Setting, and Participants: Data were obtained from the Epidemiology of Hearing Loss Study (EHLS), a longitudinal, population-based study in Beaver Dam, Wisconsin...
April 26, 2018: JAMA Otolaryngology—Head & Neck Surgery
Jad G Sfeir, Matthew T Drake, Elizabeth J Atkinson, Sara J Achenbach, Jon J Camp, Amanda J Tweed, Louise K McCready, Lifeng Yu, Mark C Adkins, Shreyasee Amin, Sundeep Khosla
Central quantitative computed tomography (QCT) is increasingly used in clinical trials and practice to assess bone mass or strength and to evaluate longitudinal changes in response to drug treatment. Current studies utilize single-energy (SE) QCT scans, which may be confounded both by the amount of bone marrow fat at baseline and changes in marrow fat over time. However, the extent to which marrow fat changes either underestimate volumetric BMD (vBMD) measurements at baseline or under-/overestimate longitudinal changes in vivo in humans remains unclear...
April 25, 2018: Bone
Conor Tweed, Andrew Nunn
No abstract text is available yet for this article.
May 1, 2018: International Journal of Tuberculosis and Lung Disease
Jana Cela, John K S Tweed, Anushen Sivakumaran, Michael R F Lee, Luis A J Mur, Sergi Munné-Bosch
Tocopherols are lipid-soluble antioxidants that contribute to plant resistance to abiotic stresses. However, it is still unknown to what extent alterations in tocopherol composition can affect the plant response to biotic stresses. The response to bacterial and fungal attack of the vte1 mutant of Arabidopsis thaliana, which lacks both α- and γ-tocopherol, was compared to that of the vte4 mutant (which lacks α- but accumulates γ-tocopherol) and the wild type (with accumulates α-tocopherol in leaves). Both mutants exhibited similar kinetics of cell death and resistance in response to Pseudomonas syringae...
March 28, 2018: Plant Physiology and Biochemistry: PPB
Tim J Wilkinson, Michael J Tweed
We describe programmatic assessment and the problems it might solve in relation to assessment and learning, identify some models implemented internationally, and then outline what we believe are programmatic assessment's key components and what these components might achieve. We then outline some issues around implementation, which include blueprinting, data collection, decision making, staff support, and evaluation. Rather than adopting an all-or-nothing approach, we suggest that elements of programmatic assessment can be gradually introduced into traditional assessment systems...
2018: Advances in Medical Education and Practice
Conor Duncan Tweed, Genevieve Helen Wills, Angela M Crook, Rodney Dawson, Andreas H Diacon, Cheryl E Louw, Timothy D McHugh, Carl Mendel, Sarah Meredith, Lerato Mohapi, Michael E Murphy, Stephen Murray, Sara Murthy, Andrew J Nunn, Patrick P J Phillips, Kasha Singh, M Spigelman, S H Gillespie
BACKGROUND: Drug-induced liver injury (DILI) is a common complication of tuberculosis treatment. We utilised data from the REMoxTB clinical trial to describe the incidence of predisposing factors and the natural history in patients with liver enzyme levels elevated in response to tuberculosis treatment. METHODS: Patients received either standard tuberculosis treatment (2EHRZ/4HR), or a 4-month regimen in which moxifloxacin replaced either ethambutol (isoniazid arm, 2MHRZ/2MHR) or isoniazid (ethambutol arm, 2EMRZ/2MR)...
March 28, 2018: BMC Medicine
Robert W Aldridge, Alistair Story, Stephen W Hwang, Merete Nordentoft, Serena A Luchenski, Greg Hartwell, Emily J Tweed, Dan Lewer, Srinivasa Vittal Katikireddi, Andrew C Hayward
BACKGROUND: Inclusion health focuses on people in extremely poor health due to poverty, marginalisation, and multimorbidity. We aimed to review morbidity and mortality data on four overlapping populations who experience considerable social exclusion: homeless populations, individuals with substance use disorders, sex workers, and imprisoned individuals. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, and the Cochrane Library for studies published between Jan 1, 2005, and Oct 1, 2015...
November 10, 2017: Lancet
Birte Melsen
No abstract text is available yet for this article.
September 2017: Journal of Clinical Orthodontics: JCO
E J Tweed, G M Allardice, P McLoone, D S Morrison
OBJECTIVES: To investigate the relationship between socio-economic circumstances and cancer incidence in Scotland in recent years. STUDY DESIGN: Population-based study using cancer registry data. METHODS: Data on incident cases of colorectal, lung, female breast, and prostate cancer diagnosed between 2001 and 2012 were obtained from a population-based cancer registry covering a population of approximately 2.5 million people in the West of Scotland...
January 2018: Public Health
Mike Tweed
No abstract text is available yet for this article.
November 9, 2017: Medical Teacher
S Tweed, H Celle-Jeanton, L Cabot, F Huneau, V De Montety, N Nicolau, Y Travi, M Babic, L Aquilina, V Vergnaud-Ayraud, M Leblanc
The groundwater irrigation expansion, and its multiple potential impacts on the quantity and quality of water resources, is not just restricted to areas that are water limited. In this study we present the seasonal impacts irrigation practices can have on groundwater resources in a temperate humid region, where the average annual rain/PET ratio is 1.0. In this system the irrigation expansion is solely supported by groundwater pumping, but despite this only 5 boreholes are monitored for hydraulic head data. In this study, we compensate the scarce hydrophysical dataset by incorporating environmental tracers (major ions, δ18 O, δ2 H and δ13 C) and dating tracers (3 H, CFC, SF6 and14 C)...
February 1, 2018: Science of the Total Environment
Lalima Kumari, Anuranjan Das
OBJECTIVE: The purpose of this study was to establish Tweed's cephalometric norms for Indian Bengali population and to compare it with Caucasian norms. MATERIALS AND METHODS: The participants were of 50 adults with normal occlusion and pleasant profile. Lateral cephalograms were taken in natural head position, and cephalometric norms were established using Tweeds diagnostic triangle. RESULTS: The study showed more proclined lower incisors in comparison with Caucasians...
July 2017: European Journal of Dentistry
Lucian Gideon Conway, Kate Bongard, Victoria Plaut, Laura Janelle Gornick, Daniel P Dodds, Thomas Giresi, Roger G Tweed, Meredith A Repke, Shannon C Houck
What kinds of physical environments make for free societies? The present research investigates the effect of three different types of ecological stressors (climate stress, pathogen stress, and frontier topography) on two measurements of governmental restriction: Vertical restriction involves select persons imposing asymmetrical laws on others, while horizontal restriction involves laws that restrict most members of a society equally. Investigation 1 validates our measurements of vertical and horizontal restriction...
October 2017: Personality & Social Psychology Bulletin
Amanda Lucas, Ken N Borce, Anne Whitford Fast, Jodi Walker-Tweed
No abstract text is available yet for this article.
April 2018: Journal of Nursing Care Quality
Roselaine Sprenger, Luciano Augusto Cano Martins, Júlio Cesar Bento Dos Santos, Carolina Carmo de Menezes, Giovana Cherubini Venezian, Viviane Veroni Degan
BACKGROUND: Craniofacial growth pattern has been correlated with variations in size of the upper airway spaces. The objective of this study was to evaluate the nasopharyngeal, oropharyngeal, and hypopharyngeal airway spaces variations according to the craniofacial growth pattern, by comparing brachyfacial, mesofacial, and dolichofacial in Angle Class I individuals. METHODS: To measure the spaces, 45 lateral teleradiographs were used and divided into 3 groups per the craniofacial growth pattern, determined by the Tweed cephalometry angular measurements: FMA and Y-axis...
December 2017: Progress in Orthodontics
Pilar Anton-Martin, Janna Journeycake, Vinai Modem, Sailaja Golla, Lakshmi Raman, Jefferson Tweed, Cindy Darnell-Bowens
We performed a retrospective matched case-control study evaluating whether the traditional coagulation profile predicts cerebrovascular events in children on extracorporeal membrane oxygenation (ECMO) in a 71 bed intensive care unit at a tertiary children's hospital. Between 2009 and 2014, 241 neonates and children were initiated on ECMO. The cumulative 5 year incidence of intracranial hemorrhage and infarct was 9.2% and 7.9%, respectively. Thirty-six cases were individually matched 1:1 with control subjects based on age, primary diagnosis, ECMO type, cannulation site, and the presence of pre-ECMO coagulopathy...
November 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
M J Tweed, S Stein, T J Wilkinson, G Purdie, J Smith
BACKGROUND: Clinicians making decisions require the ability to self-monitor and evaluate their certainty of being correct while being mindful of the potential consequences of alternative actions. For clinical students, this ability could be inferred from their responses to multiple-choice questions (MCQ) by recording their certainty in correctness and avoidance of options that are potentially unsafe. METHODS: Response certainty was assessed for fifth year medical students (n = 330) during a summative MCQ examination by having students indicate their certainty in each response they gave on the exam...
June 28, 2017: BMC Medical Education
John Kim, Fariya Mostafa, Douglas Blair Tweed
BACKGROUND: Learning algorithms come in three orders of complexity: zeroth-order (perturbation), first-order (gradient descent), and second-order (e.g., quasi-Newton). But which of these are used in the brain? We trained 12 people to shoot targets, and compared them to simulated subjects that learned the same task using various algorithms. RESULTS: Humans learned significantly faster than optimized zeroth-order algorithms, but slower than second-order ones. CONCLUSIONS: Human visuomotor learning is too fast to be explained by zeroth-order processes alone, and must involve first or second-order mechanisms...
June 12, 2017: BMC Neuroscience
Na Li, Bo Hu, Fanglin Mi, Jinlin Song
The present study was conducted to evaluate the three-dimensional (3D) cephalometry accuracy of cone-beam computed tomography (CBCT). A total of 40 newly diagnosed orthodontic patients (including 18 males and 22 females; age range, 12-18 years) were subjected to CBCT scanning and X-ray imaging in order to obtain lateral cephalograms. The 3D CBCT cephalograms were reconstructed and measured with in vivo 5.1 software, and compared with the results from the conventional 2D lateral cephalograms. Measurements in the two images were performed twice using the Steiner and Tweed standards and a single analyzer paired t-test was used to analyze the differences between the two cephalometric methods...
May 2017: Experimental and Therapeutic Medicine
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