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https://www.readbyqxmd.com/read/28446018/development-of-personalized-urination-recognition-technology-using-smart-bands
#1
Sung-Jong Eun, Taeg-Keun Whangbo, Dong Kyun Park, Khae-Hawn Kim
PURPOSE: This study collected and analyzed activity data sensed through smart bands worn by patients in order to resolve the clinical issues posed by using voiding charts. By developing a smart band-based algorithm for recognizing urination activity in patients, this study aimed to explore the feasibility of urination monitoring systems. METHODS: This study aimed to develop an algorithm that recognizes urination based on a patient's posture and changes in posture...
April 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28445817/nanostructural-and-mechanical-property-changes-to-spider-silk-as-a-consequence-of-insecticide-exposure
#2
Marco Benamú, Mariángeles Lacava, Luis F García, Martín Santana, Jian Fang, Xungai Wang, Sean J Blamires
Neonicotinoids are one of the world's most extensively used insecticides, but their sub-lethal influences on non-target and beneficial organisms are not well known. Here we exposed the orb web spider Parawixia audax, which is found on arable lands in Uruguay, to a sub-lethal concentration of the broad spectrum insecticide Geonex (thiamethoxam + lambda-cyhalothrin) and monitored their web building. We collected their major ampullate silk and subjected it to tensile tests, wide-angle X-ray diffraction (WAXS) analysis, and amino acid composition analysis...
April 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28445798/episiotomy-what-angle-do-you-cut-to-the-midline
#3
Kenneth Ma, Louise Byrd
OBJECTIVE: Although episiotomies are the commonest obstetric procedure performed the technique of performing one varies amongst obstetricians and midwives. The angle of episiotomy to the midline in particular has been shown to influence the risk of developing obstetric anal sphincter injuries (OASIS). In order to identify the differences in technique and to identify targets for training we undertook a practice survey of episiotomies to analyse the differences in technique between grades of obstetricians and midwives...
April 11, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28445765/in-line-monitoring-and-optimization-of-powder-flow-in-a-simulated-continuous-process-using-transmission-near-infrared-spectroscopy
#4
Md Anik Alam, Zhenqi Shi, James K Drennen, Carl A Anderson
In-line monitoring of continuous powder flow is an integral part of the continuous manufacturing process of solid oral dosage forms in the pharmaceutical industry. Specifically, monitoring downstream from loss-in-weight (LIW) feeders and/or continuous mixers provides important data about the state of the process. Such measurements support control of the process and thereby enhance product quality. Near Infrared Spectroscopy (NIRS) is a potential PAT tool to monitor the homogeneity of a continuous powder flow stream in pharmaceutical manufacturing...
April 23, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28445752/refolding-of-sds-unfolded-proteins-by-nonionic-surfactants
#5
Jørn Døvling Kaspersen, Anne Søndergaard, Daniel Jhaf Madsen, Daniel E Otzen, Jan Skov Pedersen
The strong and usually denaturing interaction between anionic surfactants (AS) and proteins/enzymes has both benefits and drawbacks: for example, it is put to good use in electrophoretic mass determinations but limits enzyme efficiency in detergent formulations. Therefore, studies of the interactions between proteins and AS as well as nonionic surfactants (NIS) are of both basic and applied relevance. The AS sodium dodecyl sulfate (SDS) denatures and unfolds globular proteins under most conditions. In contrast, NIS such as octaethylene glycol monododecyl ether (C12E8) and dodecyl maltoside (DDM) protect bovine serum albumin (BSA) from unfolding in SDS...
April 25, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28445750/effect-of-phosphorylation-on-a-human-like-osteopontin-peptide
#6
Samuel Lenton, Marco Grimaldo, Felix Roosen-Runge, Frank Schreiber, Tommy Nylander, Roger Clegg, Carl Holt, Michael Härtlein, Victoria García Sakai, Tilo Seydel, Susana C Marujo Teixeira
The last decade established that the dynamic properties of the phosphoproteome are central to function and its modulation. The temporal dimension of phosphorylation effects remains nonetheless poorly understood, particularly for intrinsically disordered proteins. Osteopontin, selected for this study due to its key role in biomineralization, is expressed in many species and tissues to play a range of distinct roles. A notable property of highly phosphorylated isoforms of osteopontin is their ability to sequester nanoclusters of calcium phosphate to form a core-shell structure, in a fluid that is supersaturated but stable...
April 25, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28445639/toward-covalent-organic-frameworks-bearing-three-different-kinds-of-pores-the-strategy-for-construction-and-cof-to-cof-transformation-via-heterogeneous-linker-exchange
#7
Cheng Qian, Qiao-Yan Qi, Guo-Fang Jiang, Fu-Zhi Cui, Yuan Tian, Xin Zhao
Covalent organic frameworks (COFs) are an emerging class of crystalline porous organic materials which are fabricated via reticular chemistry. Their topologic structures can be precisely predicted on the basis of the structures of building blocks. However, constructing COF with complicated structures has remained a great challenge, due to the limited strategies that can access to structural complexity of COFs. In this work, we have developed a new approach to produce COFs bearing three different kinds of pores...
April 26, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28445553/a-novel-rat-head-gaze-determination-system-based-on-optomotor-responses
#8
Mengbo You, Toshiyuki Yamane, Hiroshi Tomita, Eriko Sugano, Takuya Akashi
The optomotor response of animals is commonly used to measure their visual performance, e.g., rats of different genetically altered strains or various drug tests. With the presentation of stimuli using computer screens or projectors, the common idea focuses on measuring the eye movement or head and/or body movement to characterize changes of the head gaze. However, traditional methods rely on either the invasive fixation of animals, or the judgment of a human observer who reports the stimulus-tracking movements...
2017: PloS One
https://www.readbyqxmd.com/read/28445372/longitudinal-photogrammetric-analysis-of-the-columellar-labial-angle-following-primary-repair-of-bilateral-cleft-lip-and-nasal-deformity
#9
S Alex Rottgers, So Young Lim, Amber M Hall, David Zurakowski, John B Mulliken
BACKGROUND: The changing nasolabial dimensions after repair of bilateral cleft lip and nasal deformity can be documented by anthropometry; however, the columellar-labial angle is rarely measured. METHODS: This is a study of white patients who had synchronous repair of bilateral cleft lip performed by one surgeon (J.B.M.). The columellar-labial angle was measured on lateral photographs with the subject in neutral head position. Average values for columellar-labial angle at two or more time points were analyzed with a general estimating equation and cubic modeling...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28445368/correcting-concavity-of-rabbit-auricular-cartilage-comparison-of-single-scoring-incisions-with-butyl-cyanoacrylate-aided-techniques
#10
Yalcin Yontar, İrfan Özyazgan
BACKGROUND: The authors present the results of an experimental study in which four different techniques were used for the correction of concave rabbit auricular cartilage. METHODS: Sixteen New Zealand adult male rabbits were used in the study. Butyl cyanoacrylate-aided cartilage graft fixation and butyl cyanoacrylate-aided bone graft fixation and scoring technique, alone or combined with butyl cyanoacrylate application, were performed to correct the concavity of rabbit auricular cartilage...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28445294/unilateral-versus-bilateral-percutaneous-kyphoplasty-for-osteoporotic-vertebral-compression-fractures-a-meta-analysis
#11
Wenli Chang, Xinyan Zhang, Ning Jiao, Peizhi Yuwen, Yanbin Zhu, Fei Zhang, Wei Chen
BACKGROUND: The debate on the efficacy of unilateral percutaneous kyphoplasty (UPKP) and bilateral percutaneous kyphoplasty (BPKP) for the treatment of osteoporotic vertebral compression fractures (OVCFs) is ongoing.This meta-analysis aimed to evaluate the clinical results of UPKP and BPKP in the treatment of OVCFs. METHODS: Web of Science, PubMed, Embase, and the Chinese Biomedical Database publication databases were searched using a date range of January 2008 to November 2016, for studies comparing UPKP and BPKP for the treatment of OVCFs...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445165/non-diverging-analytical-expression-for-the-sensitivity-of-converging-spect-collimators
#12
Jarno van Roosmalen, Marlies C Goorden
Accurate analytical expressions for collimator resolution and sensitivity are important tools in the optimization of SPECT systems. However, presently known expressions for the sensitivity of converging collimators either diverge near the focal point or focal line(s), or are only valid on the collimator axis. As a result, these expressions are unsuitable to calculate volumetric sensitivity for e.g. short-focal length collimators that focus inside the object to enhance sensitivity. To also enable collimator optimization for these geometries, we here present non-diverging sensitivity formulas for astigmatic, cone beam and fan beam collimators that are applicable over the full collimator's field-of-view...
April 26, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28445077/effect-of-epiretinal-membranes-on-antivascular-endothelial-growth-factor-treatment-for-neovascular-age-related-macular-degeneration
#13
Han Joo Cho, Jae Min Kim, Hyoung Seok Kim, Dong Won Lee, Chul Gu Kim, Jong Woo Kim
PURPOSE: To evaluate the effect of epiretinal membranes (ERMs), detected with spectral-domain optical coherence tomography (SD-OCT), on the outcome of antivascular endothelial growth factor (VEGF) treatment for neovascular age-related macular degeneration (nAMD). METHODS: A total of 434 eyes with treatment-naive nAMD were retrospectively included and analyzed. All patients were administered an initial series of 3 monthly loading injections of ranibizumab or aflibercept, followed by further injections as required...
April 26, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28445068/experimental-demonstration-of-230%C3%A2-phase-modulation-in-gate-tunable-graphene-gold-reconfigurable-mid-infrared-metasurfaces
#14
Michelle C Sherrott, Philip W C Hon, Katherine T Fountaine, Juan C Garcia, Samuel M Ponti, Victor Watson Brar, Luke A Sweatlock, Harry A Atwater
Metasurfaces offer significant potential to control far-field light propagation through the engineering of amplitude, polarization, and phase at an interface. We report here phase modulation of an electronically reconfigurable metasurface and demonstrate its utility for mid-infrared beam steering. Using a gate-tunable graphene-gold resonator geometry, we demonstrate highly tunable reflected phase at multiple wavelengths and show up to 237° phase modulation range at an operating wavelength of 8.50 μm. We observe a smooth monotonic modulation of phase with applied voltage from 0° to 206° at a wavelength of 8...
April 26, 2017: Nano Letters
https://www.readbyqxmd.com/read/28445003/a-multiscale-approach-for-determining-the-morphology-of-endothelial-cells-at-a-coronary-artery
#15
Hossein Ali Pakravan, Mohammad Said Saidi, Bahar Firoozabadi
The morphology of endothelial cells (ECs) may be an indication for determining the atheroprone sites. Until now, there is not any clinical imaging technique to visualize the morphology of ECs at the arteries. The present study, introduces a computational technique for determining the morphology of ECs. This technique is a multiscale simulation, consisting the artery-scale and the cell-scale. The artery-scale is a FSI simulation. The input for the artery-scale is the geometry of the coronary artery (CA), dynamic curvature of the artery due to the cardiac motion, blood flow, blood pressure, heart rate, and the mechanical properties of the blood and the arterial wall, which these quantities can be obtained for a specific patient...
April 26, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28444997/a-holistic-view-of-the-effects-of-episiotomy-on-pelvic-floor
#16
Dulce A Oliveira, Marco P L Parente, Begoña Calvo, Teresa Mascarenhas, Renato M Natal Jorge
Vaginal delivery is commonly accepted as a risk factor in pelvic floor dysfunction (PFD), however, other obstetric procedures (episiotomy) are still controversial. In this work, to analyze the relationship between episiotomy and pelvic floor function, a finite element model (FEM) of the pelvic cavity is used considering the pelvic floor muscles (PFM) with damaged regions from spontaneous vaginal delivery, and from deliveries with episiotomy. Common features assessed at screening of PFD are evaluated during numerical simulations of both Valsalva maneuver and contraction...
April 26, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28444940/h-reflex-and-m-wave-recordings-effect-of-pressure-application-to-the-stimulation-electrode-on-the-assessment-of-evoked-potentials-and-subject-s-discomfort
#17
Thomas Cattagni, Angèle N Merlet, Christophe Cornu, Marc Jubeau
This study aimed to compare the effect of different types of pressure applied to the stimulation electrode on assessing the efficiency of Ia-α-motoneuron transmission of the soleus muscle and the associated discomfort using electrical nerve stimulation. Twelve healthy young adults participated in three experimental sessions (one for each knee angle). The amplitudes of the maximal Hoffmann reflex (Hmax ) and motor potential (Mmax ) were recorded from the soleus muscle at 0°, 30° and 90° knee angles (0° full extension) through three pressure applications to the stimulation electrode: no pressure, pressure with manual application and pressure using adhesive tape...
April 26, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28444785/liquid-crystalline-elastomers-with-gold-nanoparticle-cross-linkers
#18
Michał Wójcik, Jaroslaw Wrobel, Zuzanna Janczuk, Jozef Mieczkowski, Ewa Gorecka, Joonmyung Choi, Maenghyo Cho, Damian Pociecha
Embedding nanoparticles in a responsive polymer matrix is a formidable way to fabricate hybrid materials with predesigned properties and prospective applications in actuators, mechanically tunable optical elements or electroclinic films. However, achieving chemical compatibility between nanoparticles and organic matter is not trivial and often results in disordered structures. Herein we show that using nanoparticles as exclusive cross-linkers in the preparation of liquid-crystalline polymers can yield long-range ordered liquid-crystalline elastomers with high loading of well dispersed nanoparticles, as confirmed with small angle XRD measurements...
April 26, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28444438/effect-and-safety-of-early-weight-bearing-on-the-outcome-after-open-wedge-high-tibial-osteotomy-a-systematic-review-and-meta-analysis
#19
O-Sung Lee, Soyeon Ahn, Yong Seuk Lee
INTRODUCTION: The purpose of this systematic review and meta-analysis was to evaluate the effectiveness and safety of early weight-bearing by comparing clinical and radiological outcomes between early and traditional delayed weight-bearing after OWHTO. MATERIALS AND METHODS: A rigorous and systematic approach was used. The methodological quality was also assessed. Results that are possible to be compared in two or more than two articles were presented as forest plots...
April 25, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28444433/boundaries-of-the-thoracic-paravertebral-space-potential-risks-and-benefits-of-the-thoracic-paravertebral-block-from-an-anatomical-perspective
#20
Esther A C Bouman, Judith M Sieben, Andrea J R Balthasar, Elbert A Joosten, Hans-Fritz Gramke, Maarten van Kleef, Arno Lataster
PURPOSE: Thoracic paravertebral block (TPVB) may be an alternative to thoracic epidural analgesia. A detailed knowledge of the anatomy of the TPV-space (TPVS), content and adnexa is essential in understanding the clinical consequences of TPVB. The exploration of the posterior TPVS accessibility in this study allows (1) determination of the anatomical boundaries, content and adnexa, (2) description of an ultrasound-guided spread of low and high viscous liquid. METHODS: In two formalin-fixed specimens, stratification of the several layers and the 3D-architecture of the TPVS were dissected, observed and photographed...
April 25, 2017: Surgical and Radiologic Anatomy: SRA
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