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https://www.readbyqxmd.com/read/29336136/international-clinical-protocol-on-vestibular-disorders-dizziness
#1
Kostiantyn Trinus, Claus-Frenz Claussen
26-28 May at 43 Congress of Neurootological and Equilibriometric Society (Budapest, Hungary) International Clinical Protocol on Vestibular Disorders (Dizziness) being discussed and accepted as Consensus Document. Cochrane reports estimates that dizziness has prevalence of 22.9% in the last 12 months and an incidence of 3.1%. Only 1.8% of adults consulted a physician in the last 12 months. Cochrane reviews suggest that the evidence base for dizziness evaluation is weak, thus necessitates the creation of evidence-based document...
December 1, 2017: International Tinnitus Journal
https://www.readbyqxmd.com/read/29330601/assessment-of-vestibular-evoked-myogenic-potentials-and-video-head-impulse-test-in-type-2-diabetes-mellitus-patients-with-or-without-polyneuropathy
#2
Mehmet Kalkan, Ali Bayram, Ferhat Gökay, Hasan Selçuk Cura, Cemil Mutlu
This study aimed to compare cervical vestibular-evoked myogenic potentials (cVEMP), ocular vestibular-evoked myogenic potentials (oVEMP) and video head impulse test (vHIT) results between patients with type 2 diabetes mellitus (DM) or diabetic polyneuropathy (DPN) and healthy controls to determine vestibular end-organ pathologies. The participants in the present study consisted of three groups: the type 2 DM group (n = 33 patients), the DPN group (n = 33 patients), and the age- and sex-matched control group (n = 35)...
January 13, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29317498/identification-and-characterization-of-a-translation-arrest-motif-in-vemp-by-systematic-mutational-analysis
#3
Hiroyuki Mori, Sohei Sakashita, Jun Ito, Eiji Ishii, Yoshinori Akiyama
VemP (Vibrio protein export monitoring polypeptide) is a secretory protein comprising 159 amino acid residues, which functions as a secretion monitor in Vibrio and regulates expression of the downstream V.secDF2 genes. When VemP export is compromised, its translation specifically undergoes elongation arrest at the position where the Gln156 codon of vemP encounters the P-site in the translating ribosome, resulting in upregulation of V.SecDF2 production. Although our previous study suggests that many residues in a highly-conserved C-terminal 20-residue region of VemP contribute to its elongation arrest, the exact role of each residue remains unclear...
January 9, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29305208/vestibulo-cochlear-function-in-inflammatory-neuropathies
#4
Marisa Blanquet, Jens A Petersen, Antonella Palla, Dorothe Veraguth, Konrad P Weber, Dominik Straumann, Alexander A Tarnutzer, Hans H Jung
OBJECTIVE: We aimed to quantify peripheral-vestibular deficits that may contribute to imbalanced stance/gait in patients with inflammatory neuropathies. METHODS: Twenty-one patients (58 ± 15 y [mean age ± 1SD]; chronic-inflammatory-demyelinating-polyneuropathy = 10, Guillain-Barré Syndrome = 5, Anti-MAG peripheral neuropathy = 2, multifocal-motor-neuropathy = 4) were compared with 26 healthy controls. All subjects received video-head-impulse testing (vHIT), caloric irrigation and cervical/ocular vestibular-evoked myogenic-potentials (VEMPs)...
December 20, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29283093/anterior-cervical-disc-fusion-does-not-affect-the-presence-of-cervical-vestibular-evoked-myogenic-potential
#5
Ioannis Kastanioudakis, Panagiotis Saravakos, Andreas Zigouris, Vasileios Ragos, Oliver Reichel, Nafsika Ziavra
OBJECTIVE: Cervical spondylosis and cervical disk herniation are the most frequent forms of degenerative disease in the cervical spine. Surgical treatment mainly includes anterior cervical disk fusion. However, information concerning vestibular-evoked myogenic potential (VEMP) recording in patients undergoing cervical spine surgery is limited. The present prospective study aimed to investigate the effect of anterior disk fusion surgery on cervical VEMP (cVEMP) parameters. MATERIALS AND METHODS: Twenty-five patients were enrolled in this study, and 20 patients (10 men and 10 women) completed cVEMP testing...
December 14, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29282350/assessment-tools-for-use-in-patients-with-m%C3%A3-ni%C3%A3-re-disease-an-update
#6
Andrea Ciorba, Piotr Henryk Skarżyński, Virginia Corazzi, Chiara Bianchini, Claudia Aimoni, Stavros Hatzopoulos
A number of electrophysiological tests have been proposed for the initial diagnostic assessment or for the follow-up phase of patients affected by Ménière disease. The most common are: (i) vestibular evoked myogenic potentials (VEMPs); (ii) electrocochleography (ECochG); and (iii) otoacoustic emissions (OAEs). This paper presents the latest clinical developments with these 3 testing modalities. The PubMed, Embase, and Cinahl databases were searched from 2006 to December 2016. Full-text articles were obtained in cases where the title, abstract, or key words suggested that the study may be eligible for this review...
December 28, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29242950/superior-canal-dehiscence-syndrome-diagnosis-with-vestibular-evoked-myogenic-potentials-and-fremitus-nystagmus
#7
R Gürkov, C Jerin, W Flatz, R Maxwell
BACKGROUND: Superior canal dehiscence syndrome (SCDS) is a relatively rare neurotological disorder that is characterized by a heterogeneous clinical picture. Recently, vestibular evoked myogenic potential (VEMP) measurement was established for the diagnosis of SCDS. In the present study, a case series of patients with SCDS were analyzed, with a focus on VEMP. METHODS: Four patients with SCDS were prospectively examined with ocular VEMP (oVEMP) and cervical VEMP (cVEMP)...
December 14, 2017: HNO
https://www.readbyqxmd.com/read/29227983/bone-conducted-vestibular-evoked-myogenic-potentials-before-and-after-stapes-surgery
#8
Kazuyuki Akazawa, Shigeto Ohta, Kenzo Tsuzuki, Masafumi Sakagami
OBJECTIVE: To identify whether stapes surgery causes otolith dysfunction using bone-conducted vestibular-evoked myogenic potentials (VEMPs). STUDY DESIGN: Prospective study. SETTING: Hyogo College of Medicine Hospital. PATIENTS: Twenty primary ears (19 otosclerosis, 1 congenital stapes fixation) in 17 patients (2 men, 15 women; mean age 51 yr, range 20-68 yr) who had normal cervical VEMP (cVEMP) and ocular VEMP (oVEMP) results with bone-conducted stimulation were included...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29224712/superior-semicircular-canal-dehiscence-diagnosis-and-management
#9
REVIEW
Christine Mau, Naveed Kamal, Saiaditya Badeti, Renuka Reddy, Yu-Lan Mary Ying, Robert W Jyung, James K Liu
The authors provide an update on the clinical manifestations, diagnosis and various approaches to the treatment of superior semicircular canal dehiscence (SSCD). SSCD is a rare condition where the bone overlying the superior semicircular canal thins or dehisces causing characteristic clinical findings. Since this was first reported in 1998 by Minor and colleagues, there has been much advancement made in terms of diagnosis and treatment. Signs and symptoms include a wide variation of both vestibular and auditory manifestations...
December 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29189298/laboratory-examinations-for-the-vestibular-system
#10
Raymond van de Berg, Sally Rosengren, Herman Kingma
PURPOSE OF REVIEW: In the last decades, researchers suggested that clinical assessment of labyrinthine function in detail became easy thanks to video head impulse tests (VHITs), vestibular evoked myogenic potential test (VEMP) and video-oculography (VOG). It has been argued that they can replace electronystagmography, the caloric and rotatory chair tests. This review addresses the latest evaluations of these tests and the opportunities they offer, but also the limitations in clinical practice...
February 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29142084/impaired-vestibular-responses-in-internuclear-ophthalmoplegia-association-and-dissociation
#11
Seo-Young Choi, Hyo-Jung Kim, Ji-Soo Kim
OBJECTIVE: To determine the role of the medial longitudinal fasciculus (MLF) in conveying vestibular signals. METHODS: In 10 patients with isolated acute unilateral internuclear ophthalmoplegia (INO) due to an acute stroke, we performed comprehensive vestibular evaluation using video-oculography, head impulse tests with a magnetic search coil technique, bithermal caloric tests, tests for the ocular tilt reaction, and measurements of subjective visual vertical and cervical and ocular vestibular evoked myogenic potentials (VEMPs)...
December 12, 2017: Neurology
https://www.readbyqxmd.com/read/29080887/evaluation-of-vestibular-functions-in-patients-with-vogt-koyanagi-harada-disease
#12
Keishi Fujiwara, Shinya Morita, Kimiko Hoshino, Atsushi Fukuda, Yuji Nakamaru, Akihiro Homma
Vogt-Koyanagi-Harada (VKH) disease is an idiopathic, multisystem autoimmune disorder characterized by bilateral, diffuse granulomatous uveitis associated with neurological, audiovestibular, and dermatological manifestations. The purpose of this study is to investigate vestibular functions in patients with VKH disease. A total of 43 patients with VKH disease in Hokkaido University Hospital were enrolled in this study. Subjective symptoms such as dizziness or vertigo and the results of various vestibular examinations including nystagmus testing, caloric testing, and vestibular-evoked myogenic potential (VEMP) testing were investigated...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29057523/aging-related-changes-in-the-cortical-processing-of-otolith-information-in-humans
#13
Peter Zu Eulenburg, Ria Maxine Ruehl, Pia Runge, Marianne Dieterich
Acoustic short tone bursts (STB) trigger ocular and cervical vestibular evoked myogenic potentials (oVEMPs/cVEMPs) by activating irregular otolith afferents. Simultaneously, STBs introduce an artificial net acceleration signal of otolith origin into the vestibular network. VEMP parameters as diagnostic otolith processing markers have been shown to decline after the age of thirty. To delineate the differential effects of healthy aging on the cortical vestibular subnetwork processing otolith information, we measured cVEMPs and the differential effects of unilateral STB in three age groups (20-40, 40-60, 60+; n=42) using functional neuroimaging...
October 23, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28980586/-the-importance-of-vestibular-evoked-myogenic-potentials-for-the-assessment-of-the-otolith-function-in-the-patients-presenting-with-benign-paroxysmal-positional-vertigo
#14
N L Kunel'skaya, E V Baybakova, A L Guseva, M A Chugunova, E A Manaenkova
The objective of the present study was to evaluate the otolith function in the patients presenting with idiopathic benign paroxysmal positional vertigo (pBPPV) attributable to the occlusion of the posterior semicircular canal (PSCC) of the inner ear with the use of vestibular evoked myogenic potentials (VEMP). Cervical (cVEMP) and ocular VEMP (oVEMP) were measured in 34 patients with idiopathic pBPPV before and 7 days after the treatment by means of reposition maneuvers. The results of the repeated Dix-Hallpike test performed 7 days after the repositioning maneuver were negative in 27 patients and positive in 7 patients...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28928714/abnormal-cervical-vestibular-evoked-myogenic-potentials-predict-evolution-of-isolated-recurrent-vertigo-into-meniere-s-disease
#15
Sun-Uk Lee, Hyo-Jung Kim, Jeong-Yoon Choi, Ja-Won Koo, Ji-Soo Kim
INTRODUCTION: Vestibular-evoked myogenic potentials (VEMPs) can be abnormal in patients with idiopathic recurrent spontaneous vertigo. We aimed to determine whether abnormal cervical vestibular-evoked myogenic potentials (cVEMPs) can predict evolution of isolated recurrent vertigo into Meniere's disease (MD). METHODS: We had followed up 146 patients with isolated recurrent vertigo and an evaluation of cVEMPs for 0-142 months [median = 6, interquartile range (IQR) = 0-29] at the Dizziness Clinic of Seoul National University Bundang Hospital from June 2003 to May 2014...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28906242/safe-use-of-acoustic-vestibular-evoked-myogenic-potential-stimuli-protocol-and-patient-specific-considerations
#16
Cory D F Portnuff, Samantha Kleindienst, Jamie M Bogle
BACKGROUND: Vestibular-evoked myogenic potentials (VEMPs) are commonly used clinical assessments for patients with complaints of dizziness. However, relatively high air-conducted stimuli are required to elicit the VEMP, and ultimately may compromise safe noise exposure limits. Recently, research has reported the potential for noise-induced hearing loss (NIHL) from VEMP stimulus exposure through studies of reduced otoacoustic emission levels after VEMP testing, as well as a recent case study showing permanent sensorineural hearing loss associated with VEMP exposure...
September 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28906238/safe-stimulus-intensities-for-vemp-testing
#17
EDITORIAL
Gary P Jacobson
No abstract text is available yet for this article.
September 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28861037/the-clinical-utility-of-vestibular-evoked-myogenic-potentials-in-the-diagnosis-of-m%C3%A3-ni%C3%A3-re-s-disease
#18
REVIEW
Maxime Maheu, Jenny Marylin Alvarado-Umanzor, Audrey Delcenserie, François Champoux
Ménière's disease (MD) is a condition that has been proposed over 150 years ago, which involves audiological and vestibular manifestations, such as aural fullness, tinnitus, vertigo, and fluctuating hearing thresholds. Over the past few years, many researchers have assessed different techniques to help diagnose this pathology. Vestibular-evoked myogenic potential (VEMP) is an electrophysiological method assessing the saccule (cVEMP) and the utricule (oVEMP). Its clinical utility in the diagnosis of multiple pathologies, such as superior canal dehiscence, has made this tool a common method used in otologic clinics...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28777976/otoliths-accelerometer-and-seismometer-implications-in-vestibular-evoked-myogenic-potential-vemp
#19
Wally Grant, Ian Curthoys
Vestibular otolithic organs are recognized as transducers of head acceleration and they function as such up to their corner frequency or undamped natural frequency. It is well recognized that these organs respond to frequencies above their corner frequency up to the 2-3 kHz range (Curthoys et al., 2016). A mechanics model for the transduction of these organs is developed that predicts the response below the undamped natural frequency as an accelerometer and above that frequency as a seismometer. The model is converted to a transfer function using hair cell bundle deflection...
July 27, 2017: Hearing Research
https://www.readbyqxmd.com/read/28749204/revision-of-a-furosemide-loading-vestibular-evoked-myogenic-potential-protocol-for-detecting-endolymphatic-hydrops
#20
Toru Seo, Ko Shiraishi, Takaaki Kobayashi, Kitano Mutsukazu, Takeshi Fujita, Kazuya Saito, Katsumi Doi
OBJECTIVE: The presence of endolymphatic hydrops can be suggested by improving the amplitude of vestibular-evoked myogenic potential (VEMP) after furosemide administration (furosemide loading VEMP [FVEMP]). The authors aimed to determine a stimulation frequency and judgment criteria to ascertain whether a revised FVEMP protocol can be applied to clinical settings. METHODS: The study included 25 individuals with unilateral Meniere's disease (MD) and 11 normal healthy volunteers...
July 27, 2017: Acta Oto-laryngologica
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