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https://www.readbyqxmd.com/read/28230565/outcomes-of-transvaginal-high-uterosacral-ligaments-suspension-over-500-patient-single-center-study
#1
Rodolfo Milani, Matteo Frigerio, Alice Cola, Carlo Beretta, Federico Spelzini, Stefano Manodoro
BACKGROUND: Uterosacral ligament (USL) suspension is a safe and effective procedure in terms of anatomical, functional, and subjective outcomes for primary surgical treatment of prolapse. OBJECTIVES: There has been a renewed interest toward native tissue prolapse repair by vaginal route because of low cost and lack of mesh-related complications. Uterosacral ligaments are considered safe, effective, and durable as suspending structures for primary surgical repair of the apical compartment...
February 23, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28229196/the-impact-of-ureteral-stent-indwelling-time-on-the-treatment-of-acute-infection-caused-by-ureteral-calculi
#2
Yun-Feng Shi, Wen-Long Ju, Yi-Ping Zhu, Shu-Jie Xia, Xiao-Wen Sun
Ureteric stenting is an effective drainage method in patients with acute urinary tract infection caused by ureteral calculi; however, the optimal ureteral stent indwelling time has not been clearly defined. The aim of this study was to evaluate the effect of ureteric stent indwelling time on the treatment of acute infection secondary to urinary tract calculi. A total of 142 patients with acute infection caused by urinary tract calculi were identified retrospectively from January 2011 to August 2015 at our institution...
February 22, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28228880/crossed-nonfused-renal-ectopia-with-variant-blood-vessels-a-rare-congenital-renal-anomaly
#3
Nawal Ebrahim Al-Hamar, Khalid Khan
Crossed renal ectopia is a rare congenital anomaly, where one of the kidneys crosses the midline and lies opposite to the site of its normal ureteral insertion. Ninety percent of crossed ectopic kidneys are fused to their ipsilateral uncrossed kidney. Crossed renal ectopia without fusion is rare. We present the case of a 53-year-old male with an unusual incidental finding of crossed nonfused renal ectopia, with the left ectopic kidney lying anterior to the right kidney without fusion. The ectopic kidney had dual arterial supply: one from the aorta and another from the right renal artery...
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28225832/elevated-bilirubin-levels-are-associated-with-a-better-renal-prognosis-and-ameliorate-kidney-fibrosis
#4
Sehoon Park, Do Hyoung Kim, Jin Ho Hwang, Yong-Chul Kim, Jin Hyuk Kim, Chun Soo Lim, Yon Su Kim, Seung Hee Yang, Jung Pyo Lee
BACKGROUND: Bilirubin has been reported to protect against kidney injury. However, further studies highlighting the beneficial effects of bilirubin on renal fibrosis and chronic renal function decline are necessary. METHODS: We assessed a prospective cohort with a reference range of total bilirubin levels. The primary outcome was a 30% reduction in the estimated glomerular filtration rate (eGFR) from baseline, and the secondary outcome was a doubling of the serum creatinine levels, halving of the eGFR and the initiation of dialysis...
2017: PloS One
https://www.readbyqxmd.com/read/28224087/fragmentation-of-severely-encrusted-ureteral-stent-indwelled-for-4%C3%A2-years-in-a-boy
#5
Guangjing Tao, Guojun Wu, Lijun Yang, Fuli Wang, Chao Han, Fei Liu, Jianlin Yuan
Four years ago, a 9-year-old boy received percutaneous nephrolithotomy (PCNL) and a 5F DJS was placed thereafter. The DJS was neglected until it caused serious complications including encrustation involving the whole stent, a 5-cm-diameter vesical stone, fragmentation of DJS, and serious urinary tract infection. For this rare and complex case of pediatric lithotomy, we combined PCNL with the suprapubic cystolithotomy for complete removal of the encrusted stent and associated stones without any complications and the patient was rendered stone- and stent-free safely...
May 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28222442/transvesical-suprapubic-externalization-of-ureteral-stents-introduction-of-a-surgical-innovation-at-the-development-stage
#6
Holger Gerullis, Klaus Schwartmann, Thorsten H Ecke, Evangelos Georgas, Philip Herberg, Alexander Winter, Friedhelm Wawroschek, Dimitri Barski, Thomas Otto
BACKGROUND AND OBJECTIVES: In this study, we describe our first experiences with the new method of transvesical suprapubic externalization of ureteral stents. This method is assessed in patients with incurable ureteral obstruction and concomitant bladder dysfunction, and is classified according to the Idea, Development, Exploration, Assessment, Long-Term Study (IDEAL) recommendations. PATIENTS AND METHODS: From 2009 to 2015, transvesical suprapubic externalization of ureteral stents was applied in 14 (8 males, 6 females) patients with incurable ureteral obstruction of malignant (n = 9, 64%) or benign (n = 5; 36%) etiology...
February 22, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28222205/complex-cystine-kidney-stones-treated-with-combined-robot-assisted-laparoscopic-pyelolithotomy-and-intraoperative-renoscopy
#7
Luca Meggiato, Francesco Cattaneo, Fabio Zattoni, Fabrizio Dal Moro, Paolo Beltrami, Filiberto Zattoni
INTRODUCTION: Cystinuria, a rare autosomal recessive disease characterized by a defect in cystine renal reabsorption, can often determine complex cystine renal calculi, leading to important complications such as urinary obstruction, urinary infections, and impaired kidney function. Complex kidney stones can have a difficult management and can be very arduous to treat. CASE DESCRIPTION: We present the case of a 20-year-old Jeowah's witness woman with complex cystine renal stones treated with combined robot-assisted laparoscopic pyelolithotomy and intraoperative renoscopy...
February 18, 2017: Urologia
https://www.readbyqxmd.com/read/28221147/-update-in-the-management-of-ureteral-lithiasis-semirigid-and-flexible-ureterorenoscopy
#8
Carlos Torrecilla Ortiz, Sergi Colom Feixas
OBJECTIVE: The contribution of therapeutic ureteroscopy done by Perez Castro in 1980 varied the management algorithm for ureteral lithiasis worldwide. The techniques of Retrograde Ureteroscopy and transrenal antegrade ureteroscopy led to the abandonment of open surgery for the treatment of ureteral lithiasis. Only Shock wave lithotripsy has maintained similar success rates in selected cases. METHODS: Descriptive analysis of the semirigid and flexible ureteroscopy techniques performed in our department over the last 10 years giving detail on the technique and safety tips to increase the efficacy and efficiency of ureteroscopy...
January 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28220579/long-term-results-of-ileal-ureteric-replacement-a-25-years-single-centre-experience
#9
Arkadius Kocot, Charis Kalogirou, Daniel Vergho, Hubertus Riedmiller
OBJECTIVES: To report the long-term outcome of ileal ureteric replacement (IUR) in complex reconstruction of the urinary tract. PATIENTS AND METHODS: From 1991 to 2016, IUR was performed in 157 patients with structural or functional ureteric loss. In 52 patients, bilateral IUR became necessary. Implantation sites where either the native urinary bladder (n=79) or intestinal reservoirs (n=78). In the latter group, the technique was used at the time of primary urinary diversion (n=34), in a secondary approach (n=29) and in undiversion or conversion procedures (n=15)...
February 20, 2017: BJU International
https://www.readbyqxmd.com/read/28220189/simple-and-practical-nomograms-for-predicting-the-stone-free-rate-after-shock-wave-lithotripsy-in-patients-with-a-solitary-upper-ureteral-stone
#10
Naoya Niwa, Kazuhiro Matsumoto, Makoto Miyahara, Minami Omura, Hiroaki Kobayashi, Eiji Kikuchi, Akira Miyajima, Kazutoyo Miyata, Mototsugu Oya
PURPOSE: To develop practical nomograms for predicting the stone-free rate after shock wave lithotripsy (SWL) in patients with a solitary stone in the proximal ureter. METHODS: Between July 2006 and June 2015, 319 patients with a proximal ureteral stone who underwent preoperative non-contrast enhanced computed tomography (NCCT) and subsequently received SWL were identified. Patients' age, gender, laterality, stone size, mean and maximum Hounsfield Unit (HU) of the stone, and skin-to-stone distance (SSD) were assessed...
February 20, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28220032/pharmacologic-blockade-of-%C3%AE-v%C3%AE-1-integrin-ameliorates-renal-failure-and-fibrosis-in-vivo
#11
Yongen Chang, Wei Ling Lau, Hyunil Jo, Kazuyuki Tsujino, Leslie Gewin, Nilgun Isik Reed, Amha Atakilit, Ane Claudia Fernandes Nunes, William F DeGrado, Dean Sheppard
Activated fibroblasts are deemed the main executors of organ fibrosis. However, regulation of the pathologic functions of these cells in vivo is poorly understood. PDGF receptor β (PDGFRβ) is highly expressed in activated pericytes, a main source of fibroblasts. Studies using a PDGFRβ promoter-driven Cre system to delete αv integrins in activated fibroblasts identified these integrins as core regulators of fibroblast activity across solid organs, including the kidneys. Here, we used the same PDGFRβ-Cre line to isolate and study renal fibroblasts ex vivo We found that renal fibroblasts express three αv integrins, namely αvβ1, αvβ3, and αvβ5...
February 20, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28220029/a-novel-inhibitor-of-homeodomain-interacting-protein-kinase-2-mitigates-kidney-fibrosis-through-inhibition-of-the-tgf-%C3%AE-1-smad3-pathway
#12
Ruijie Liu, Bhaskar Das, Wenzhen Xiao, Zhengzhe Li, Huilin Li, Kyung Lee, John Cijiang He
Homeodomain interacting protein kinase 2 (HIPK2) is a critical regulator of multiple profibrotic pathways, including that of TGF-β1/Smad3. Genetic ablation of HIPK2 was shown previously to significantly reduce renal fibrosis in the experimental unilateral ureteral obstruction model and Tg26 mice, a model of HIV-associated nephropathy. To develop specific pharmacologic inhibitors of HIPK2 for antifibrotic therapy, we designed and synthesized small molecule inhibitor compounds on the basis of the predicted structure of HIPK2...
February 20, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28219588/early-removal-of-double-j-stents-decreases-urinary-tract-infections-in-living-donor-renal-transplantation-a-prospective-randomized-clinical-trial
#13
S Liu, G Luo, B Sun, J Lu, Q Zu, S Yang, X Zhang, J Dong
BACKGROUND: The optimal timing for stent removal after renal transplantation remains controversial. This article describes an interim analysis of a randomized, prospective, double-blind trial aimed at detecting differences in urological complications between early ureteral stent removal at 1 week and routine ureteral stent removal at 4 weeks. METHODS: Between October 2010 and March 2015, 103 patients who underwent living donor renal transplantation at a single center were pre-operatively randomly assigned to the early ureteral stent removal (at 1 week) group or the routine ureteral stent removal (at 4 weeks) group...
March 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28216944/ureteric-erosion-and-obstruction-a-rare-but-dreaded-complication-of-intrauterine-contraceptive-device
#14
Vinod Priyadarshi, Nidhi Sehgal, Dipanwita Sen
Though intrauterine contraceptive device (IUCD) is a safe and most frequently used long-term contraceptive method, it has some complications. Uterine perforation and intra-abdominal migration have been reported often, but a retroperitoneal migration is exceptional. Here, we are reporting an IUCD which perforated the uterus and migrated to the retroperitoneum; impinging into and obstructing left ureter causing severe hydroureteronephrosis due to the development of the left lower ureteric stricture.
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28216938/endogenous-endophthalmitis-as-a-septic-complication-postureteroscope-candiduria
#15
Fam Xeng Inn, Umi Kalthum Md Noh, Mohd Hafidzul Jasman
Ureteroscopy (URS) is commonly used by urologists to treat ureteral stones. It is a relatively low-risk procedure. Both urinary tract obstruction and contamination of instrument can cause candiduria post-URS, and this infection can be treated with an antifungal medication. Candidemia is known as hematogenous dissemination, and ocular tissue is a common invasion. However, endogenous endophthalmitis, due to postureteroscope candiduria, has not been reported up to date. This is a devastating complication that may lead to visual loss...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28216934/adrenal-myelolipoma-with-osseous-metaplasia-and-hypercortisolism
#16
Ujwal Kumar, Shivam Priyadarshi, Vinay Tomar, Rishi Raj Vohra
Adrenal myelolipomas are rare adrenal tumors generally diagnosed incidentally. A 42-year-old female reported to us with complaints of left flank pain attributable to her left ureteric calculi. On evaluation, a large adrenal mass was diagnosed along with hypercortisolism. After adrenalectomy, the histopathology revealed adrenal myelolipoma along with osseous metaplasia not reported in English literature, to the best of our knowledge till date.
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28216928/spontaneous-forniceal-rupture-can-it-be-treated-conservatively
#17
Ahmed Gaber Al-Mujalhem, Mohammed Sayed Ahmed Aziz, Mohammed Farag Sultan, Ahmed Mohammed Al-Maghraby, Mohammed Abdelmonem Al-Shazly
CONTEXT: Spontaneous forniceal rupture is one of the possible complications of urolithiasis. The mechanism of forniceal rupture is not well explained in the literature. Most of the cases presented with sudden onset of acute renal colic and diagnosed by noncontrast CT (NCCT). Until now there is no solid consensus about the ideal management of such a condition. AIM: To study indications and validity of conservative management of spontaneous caliceal rupture. SETTINGS AND DESIGN: This is an observational prospective study...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28216920/posthysterectomy-ureteric-injuries-presentation-and-outcome-of-management
#18
S B Patil, Nilesh Guru, V S Kundargi, B S Patil, Nikhil Patil, Kshitiz Ranka
PURPOSE: The purpose of the study was to evaluate the presentation and management of posthysterectomy ureteral injuries. PATIENTS AND METHODS: Fourteen patients with ureteric injuries after hysterectomy for benign diseases were evaluated. The diagnosis was done based on clinical presentation, intravenous urogram, computed tomography, cystoscopy, and retrograde pyelogram (RGP) depending on the clinical situation. RESULTS: Sixteen iatrogenic ureteric injuries in 14 patients over a 2-year period were evaluated...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28216502/-treatment-of-ureteral-fistula-and-stricture-following-renal-transplantation-with-boari-flap
#19
Peng Jin, Jinliang Xie, Jingeng Dun, Xiang Ding, Cheng Zhou, Xiangrong Zhu, Lielin Wu, Bo Yang, Gang Zhang
To estimate the incidence rate of ureteral fistula and stricture after kidney transplantation, and to evaluate the effect of bladder flap (Boari flap) on ureteral complication of the transplanted kidney. 
 Methods: The clinical data and risk factors from 270 recipients of renal transplantation, who came from the Centre of Organ Transplantation, Xiangya Hospital, Central South University from January 2010 to January 2015, were retrospectively analyzed. The surgical management included Boari flap for ureteral reconstruction, neoureterocystostomy and endoscopic therapy with double-J (DJ) stent placement...
January 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28216451/ureteric-obstruction-from-malignant-melanoma-in-both-right-double-moiety-and-left-single-moiety-ureters
#20
Brayden March, Ross John Spero Calopedos, Edward Latif, Rupert Ouyang
We report the first documented case of malignant melanoma obstructing ureters of both moieties of a duplex kidney and contralateral single moiety ureter in a 51-year-old male. The patient presented with fever, coryzal symptoms and liver function test derangement several years after two superficial spreading melanomas were excised with clear margins. Ultrasonography demonstrated hydronephroureter in both moieties of a complete right-sided duplex kidney. Retrograde pyelograms showed bilateral hydronephroureter and filling defects in all three ureters...
February 16, 2017: Urology
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