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https://www.readbyqxmd.com/read/28744072/multimodality-imaging-spectrum-of-complications-of-horseshoe-kidney
#1
Hardik U Shah, Vijayanadh Ojili
Horseshoe kidney is the most common congenital renal fusion anomaly with an incidence of 1 in 400-600 individuals. The most common type is fusion at the lower poles seen in greater than 90% of the cases, with the rest depicting fusion at the upper poles, resulting in an inverted horseshoe kidney. Embryologically, there are two theories hypothesizing the genesis of horseshoe kidney - mechanical fusion theory and teratogenic event theory. As an entity, horseshoe kidney is an association of two anatomic anomalies, namely, ectopia and malrotation...
April 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28743528/contrast-enhanced-ultrasound-as-a-radiation-free-alternative-to-fluoroscopic-nephrostogram-for-evaluating-ureteral-patency
#2
Thomas Chi, Manint Usawachintachit, Stefanie Weinstein, Maureen P Kohi, Andrew Taylor, David T Tzou, Helena C Chang, Marshall Stoller, John Mongan
PURPOSE: To compare contrast-enhanced ultrasound and fluoroscopic nephrostography in the evaluation of ureteral patency following percutaneous nephrolithotomy. MATERIALS AND METHODS: This was a prospective cohort non-inferiority study conducted after obtaining institutional review board approval. We enrolled eligible patients with kidney and proximal ureteral stones who underwent percutaneous nephrolithotomy at our center. On postoperative day 1, patients received both contrast-enhanced ultrasounds and fluoroscopic nephrostograms within 2 hours of each other to evaluate ureteral patency, the primary outcome for this study...
July 22, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28743527/effectiveness-and-complications-of-augmentation-cystoplasty-with-or-without-non-refluxing-ureteral-reimplantation-in-adult-patients-with-long-standing-bladder-dysfunction-a-single-center-11-year-experience-in-173-cases
#3
Zhaoxia Wang, Limin Liao
PURPOSE: To review our experience for effectiveness and complications of augmentation cystoplasty (AC) with or without non-refluxing ureteral reimplantation in adult patients with long-standing bladder dysfunction MATERIAL AND METHODS: We retrospectively reviewed 173 patients who underwent AC with or without ureteral re-implantation (UR) at our center from July 2005 to July 2016. Clinical data, magnetic resonance urography (MRU), and video-urodynamics (VUD) parameters were collected. The upper urinary tract dilation (UUTD) and vesicoureteral reflux (VUR) grading systems were used to evaluate upper urinary tract function...
July 22, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28743217/identifying-content-for-simulation-based-curricula-in-urology-a-national-needs-assessment
#4
Leizl Joy Nayahangan, Rikke Bølling Hansen, Karen Gilboe Lindorff-Larsen, Charlotte Paltved, Bjørn Ulrik Nielsen, Lars Konge
OBJECTIVE: Simulation-based training is well recognized in the transforming field of urological surgery; however, integration into the curriculum is often unstructured. Development of simulation-based curricula should follow a stepwise approach starting with a needs assessment. This study aimed to identify technical procedures in urology that should be included in a simulation-based curriculum for residency training. MATERIALS AND METHODS: A national needs assessment was performed using the Delphi method involving 56 experts with significant roles in the education of urologists...
July 26, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28740925/characterization-of-efficacy-and-toxicity-after-high-dose-pelvic-reirradiation-with-palliative-intent-for-genitourinary-second-malignant-neoplasms-or-local-recurrences-after-full-dose-radiation-therapy-in-the-pelvis-a-high-volume-cancer-center-experience
#5
Sophia C Kamran, Lauren C Harshman, Mandar S Bhagwat, Vinayak Muralidhar, Paul L Nguyen, Neil E Martin, Stephanie La Follette, Sarah Faso, Akila N Viswanathan, Jason A Efstathiou, Clair J Beard
PURPOSE: The use of large-field external beam reirradiation (re-RT) after pelvic radiation therapy (RT) for genitourinary (GU) cancers has not been reported. We report the results of such treatment in patients with either symptomatic GU second malignant neoplasms or locally recurrent pelvic tumors after initial RT for whom surgery or further systemic therapy was not an option. METHODS AND MATERIALS: The records of 28 consecutive patients with advanced, bulky GU malignancies treated with high-dose, large-field re-RT with palliative intent between 2008 and 2014 were retrospectively reviewed...
April 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28740917/phase-1-trial-of-preoperative-image-guided-intensity-modulated-proton-radiation-therapy-with-simultaneously-integrated-boost-to-the-high-risk-margin-for-retroperitoneal-sarcomas
#6
Thomas F DeLaney, Yen-Lin Chen, Elizabeth H Baldini, Dian Wang, Judith Adams, Shea B Hickey, Beow Y Yeap, Stephen M Hahn, Karen De Amorim Bernstein, G Petur Nielsen, Edwin Choy, John T Mullen, Sam S Yoon
PURPOSE: To conduct phase 1 and 2 trials with photon intensity modulated radiation therapy and intensity modulated proton therapy (IMPT) arms to selectively escalate the retroperitoneal sarcoma preoperative radiation dose to tumor volume (clinical target volume [CTV] 2) that is judged to be at a high risk for positive margins and aim to reduce local recurrence. We report on the IMPT study arm in phase 1. METHODS AND MATERIALS: Patients aged ≥18 years with primary or locally recurrent retroperitoneal sarcoma were treated with preoperative IMPT, 50...
January 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28739403/ileal-ureter-replacement-combined-with-boari-flap-psoas-hitch-to-treat-full-length-ureteral-defects-technique-and-initial-experience
#7
Wenlong Zhong, Yicong Du, Kunlin Yang, Steven Meng, Rongcheng Lin, Xuesong Li, Liyan Zhuang, Lin Cai, Haoran Cui, Zhisong He, Liqun Zhou
OBJECTIVES: To evaluate the feasibility of ileal ureter replacement combined with Boari flap-psoas hitch procedure for the management of full-length ureteral defects (>20 cm). METHODS: Three patients diagnosed with full-length ureteral defect were treated with our technique performed by a single surgeon between January 2015 to January 2016. All the patients had borderline renal function preoperatively. In each case, the ureteral reconstruction was performed by combining ileal ureter replacement with Boari flap-psoas hitch...
July 21, 2017: Urology
https://www.readbyqxmd.com/read/28739141/amp-activated-protein-kinase-myocardin-related-transcription-factor-a-signaling-regulates-fibroblast-activation-and-renal-fibrosis
#8
Yuguo Wang, Li Jia, Zhaoyong Hu, Mark L Entman, William E Mitch, Yanlin Wang
Chronic kidney disease is a major cause of death, and renal fibrosis is a common pathway leading to the progression of this disease. Although activated fibroblasts are responsible for the production of the extracellular matrix and the development of renal fibrosis, the molecular mechanisms underlying fibroblast activation are not fully defined. Here we examined the functional role of AMP-activated protein kinase (AMPK) in the activation of fibroblasts and the development of renal fibrosis. AMPKα1 was induced in the kidney during the development of renal fibrosis...
July 21, 2017: Kidney International
https://www.readbyqxmd.com/read/28739140/the-il-4-receptor-%C3%AE-has-a-critical-role-in-bone-marrow-derived-fibroblast-activation-and-renal-fibrosis
#9
Hua Liang, Zhengmao Zhang, Jingyin Yan, Yuguo Wang, Zhaoyong Hu, William E Mitch, Yanlin Wang
Renal fibrosis is a common pathway leading to the progression of chronic kidney disease, and bone marrow-derived fibroblasts contribute significantly to the development of renal fibrosis. However, the signaling mechanisms underlying the activation of these fibroblasts are not completely understood. Here, we examined the role of IL-4 receptor α (IL-4Rα) in the activation of myeloid fibroblasts in two experimental models of renal fibrosis. Compared with wild-type mice, IL-4Rα knockout mice accumulated fewer bone marrow-derived fibroblasts and myofibroblasts in their kidneys...
July 21, 2017: Kidney International
https://www.readbyqxmd.com/read/28736319/robotic-ureteroplasty-with-buccal-mucosa-graft-for-the-management-of-complex-ureteral-strictures
#10
Ziho Lee, Benjamin T Waldorf, Eric Y Cho, Jeffrey C Liu, Michael J Metro, Daniel D Eun
PURPOSE: Surgical management of proximal and mid ureteral strictures not amenable to primary excision and anastomosis is challenging. Although buccal mucosa graft is commonly utilized during substitution urethroplasty, its use in substitution ureteroplasty is limited. We describe our technique for robotic ureteroplasty with buccal mucosa graft for the management of complex ureteral strictures and report our outcomes. MATERIALS AND METHODS: We retrospectively reviewed 12 patients who underwent robotic ureteroplasty with buccal mucosa graft between September 2014 and June 2016...
July 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28735931/midterm-follow-up-of-ureteral-embolization-using-vascular-plugs-and-n-butyl-cyanoacrylate-glue
#11
Timothy Huber, Luke R Wilkins, Saher Sabri, Auh Whan Park, James R Stone, John F Angle, Wael E Saad, Alan H Matsumoto
This is a retrospective study of 9 consecutive female patients who underwent ureteral embolization via a "sandwich" technique with two vascular plugs and N-butyl cyanoacrylate glue for ureteral fistulae unresponsive to urinary diversion. Average age was 61 years (range, 39-77 y), average duration of diversion was 48 days (range, 2-120 d), and average follow-up was 11 months (range, 4-23 mo). Seven patients (78%) experienced immediate resolution of urinary leakage, and the other 2 (22%) required unilateral repeat treatment for resolution of leakage...
August 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28734524/endovascular-repair-of-an-arterial-pseudoaneurysm-due-to-ureteral-iliac-fistula
#12
Ana María Miguel-Sánchez, Ljubica Sarmiento-Marasovic, Jose Manuel Buisán-Bardají, Jorge Coghi-Granados, Ángel Duato Jané
No abstract text is available yet for this article.
July 19, 2017: Cirugía Española
https://www.readbyqxmd.com/read/28733910/a-review-study-to-evaluate-holmium-yag-laser-lithotripsy-with-flexible-ureteroscopy-in-patients-on-ongoing-oral-anticoagulant-therapy
#13
Bulent Altay, Bulent Erkurt, Selami Albayrak
The objective of this study was to evaluate the safety and efficacy of flexible ureteroscopy (FURS) and holmium:YAG laser lithotripsy for the treatment of upper urinary tract stones in patients on active oral anticoagulants. The records of 1081 patients who underwent flexible ureteroscopic holmium:YAG (Ho:YAG) laser lithotripsy for upper ureteral and renal calculi from 1999 to 2015 were retrospectively reviewed. A total of 84 patients on continuous oral anticoagulation or antiplatelet therapy (warfarin, aspirin, or clopidogrel) were identified...
July 22, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28733875/-management-for-unilateral-ureteric-pelvic-junction-obstruction-in-children-less-than-two-years-of-age
#14
REVIEW
Arkadiusz Miernik
No abstract text is available yet for this article.
July 21, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28733250/sphingosine-kinase-1-protects-renal-tubular-epithelial-cells-from-renal-fibrosis-via-induction-of-autophagy
#15
Chunyang Du, Yunzhuo Ren, Fang Yao, Jialiang Duan, Hui'er Zhao, Yunxia Du, Xia Xiao, Huijun Duan, Yonghong Shi
Autophagy is an important homoeostatic mechanism for the lysosomal degradation of protein aggregates and damaged cytoplasmic components. Recent studies suggest that autophagy which is induced by TGF-β1 suppresses kidney fibrosis in renal tubular epithelial cells (RTECs) of obstructed kidneys. Sphingosine kinase 1(SK1), converting sphingosine into endogenous sphingosine-1-phosphate (S1P), was shown to modulate autophagy and involved in the processes of fibrotic diseases. Since SK1 activity is also up-regulated by TGF-β1, we explored its effect on the induction of autophagy and development of renal fibrosis in this study...
July 18, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/28732671/psoas-hitch-ureteral-reimplantation-after-surgery-for-locally-advanced-and-locally-recurrent-colorectal-cancer-complications-and-oncological-outcome
#16
F van den Heijkant, T A Vermeer, E J E J Vrijhof, G A P Nieuwenhuijzen, E L Koldewijn, H J T Rutten
INTRODUCTION: The most important prognostic factor for oncological outcome of rectal cancer is radical surgical resection. In patients with locally advanced T4 rectal cancer (LARC) or locally recurrent rectal cancer (LRRC) (partial) resection of the urinary tract is frequently required to achieve radical resection. The psoas bladder hitch (PBH) technique is the first choice for reconstruction of the ureter after partial resection and this bladder-preserving technique should not influence the oncological outcome...
May 26, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28731777/induction-and-maintenance-adjuvant-mitomycin-c-topical-therapy-for-upper-tract-urothelial-carcinoma-tolerability-and-intermediate-term-outcomes
#17
Michael Metcalfe, Gavin Wagenheim, Lianchun Xiao, John Papadopoulos, Neema Navai, John W Davis, Jose A Karam, Ashish M Kamat, Christopher G Wood, Colin P Dinney, Surena F Matin
PURPOSE: Endoscopic management of upper tract urothelial carcinoma (UTUC) is associated with higher recurrences, which could be reduced by application of topical therapy. Adjuvant induction Bacillus Calmette-Guerin has shown inferior outcomes for UTUC compared to bladder cancer, and maintenance regimens for UTUC are unexplored. We report on the efficacy, safety, and tolerability of Mitomycin C (MMC) induction and maintenance adjuvant topical therapy for UTUC. MATERIALS AND METHODS: Patients with UTUC who received adjuvant topical therapy after complete endoscopic control of Ta/T1 tumors were retrospectively reviewed...
July 21, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28730297/trauma-to-the-bladder-and-ureter-a-review-of-diagnosis-management-and-prognosis
#18
REVIEW
B Phillips, S Holzmer, L Turco, M Mirzaie, E Mause, A Mause, A Person, S W Leslie, D L Cornell, M Wagner, R Bertellotti, J A Asensio
BACKGROUND: Injuries to the ureter or bladder are relatively rare. Therefore, a high level of clinical suspicion and knowledge of operative anatomy is of utmost importance for their management. Herein, a review of the literature related to the modern diagnosis, management, and prognosis for bladder and ureteral injuries is presented. METHODS: A literature search was conducted through PubMed. A thorough search of the world's literature published in English was completed...
July 20, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28729014/evaluating-ureteral-patency-in-the-post-indigo-carmine-era-a-randomized-controlled-trial
#19
Cara Grimes, Sonali Patankar, Timothy Ryntz, Nisha Philip, Khara Simpson, Mireille Truong, Connie Young, Arnold Advincula, Obianuju S Madueke-Laveaux, Ryan Walters, Cande V Ananth, Jin Hee Kim
BACKGROUND: Many gynecologic, urologic and pelvic reconstructive surgeries require accurate intra-operative evaluation of ureteral patency. OBJECTIVE: We performed a randomized controlled trial to compare surgeon satisfaction with four methods of evaluating ureteral patency during cystoscopy at the time of benign gynecologic or pelvic reconstructive surgery: oral phenazopyridine, intravenous sodium fluorescein, mannitol bladder distention and normal saline bladder distention...
July 17, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28728505/in-vitro-comparison-of-stone-fragmentation-when-using-various-settings-with-modern-variable-pulse-holmium-lasers
#20
John Roger Bell, Kristina L Penniston, Stephen Y Nakada
INTRODUCTION AND OBJECTIVE There is limited data regarding optimal laser and energy settings during stone fragmentation. We assessed effects on fragmentation using a variety of energy and frequency settings with two laser systems. METHODS Artificial stones were created using BegoStone (Streeper et al 2016). A clear PVC tube with an inner diameter of 13mm was closed at one end with a removable plug to create the in vitro ureteral and calyceal environments. The Lumenis Pulse 120H and the Cook Rhapsody H-30 holmium lasers were studied in the calyceal and ureteral models...
July 20, 2017: Journal of Endourology
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