Rosalba Hernandez, Ken Wilund, Killivalavan Solai, David Tamayo, Drew Fast, Prasakthi Venkatesan, James P Lash, Claudia M Lora, Lizet Martinez, Geovana Martin Alemañy, Angela Martinez, Soonhyung Kwon, Dana Romero, Matthew H E M Browning, Judith T Moskowitz
BACKGROUND: Depression is highly prevalent in individuals on hemodialysis, but it is infrequently identified and remains undertreated. In this paper, we present details of the methodology of a randomized controlled trial (RCT) aimed at testing the feasibility and preliminary efficacy of a 5-week positive psychological intervention in individuals on hemodialysis with comorbid depression delivered using immersive virtual reality (VR) technology. OBJECTIVE: We aim to describe the protocol and design of the Joviality trial whose main objectives are 2-fold: determine the feasibility of the Joviality VR software through metrics capturing rates of recruitment, refusal, retention, noncompliance, and adherence, as well as end-user feedback; and assess preliminary efficacy for outcomes measures of depressive symptoms, psychological well-being and distress, quality of life, treatment adherence, clinical biomarkers, and all-cause hospitalizations...
June 16, 2023: JMIR Research Protocols