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https://www.readbyqxmd.com/read/28241090/plasma-exchange-for-guillain-barr%C3%A3-syndrome
#1
REVIEW
Sylvie Chevret, Richard Ac Hughes, Djillali Annane
BACKGROUND: Guillain-Barré syndrome (GBS) is an acute paralysing disease caused by peripheral nerve inflammation. This is an update of a review first published in 2001 and last updated in 2012. OBJECTIVES: To assess the effects of plasma exchange for treating GBS. SEARCH METHODS: On 18 January 2016 we searched the Cochrane Neuromuscular Specialised Register, CENTRAL, MEDLINE, and Embase. We also searched clinical trials registries. SELECTION CRITERIA: Randomised and quasi-randomised trials of plasma exchange versus sham exchange or supportive treatment, or comparing different regimens or techniques of plasma exchange...
February 27, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28239560/risk-factors-for-hearing-impairment-among-adults-with-diabetes-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#2
Kathleen E Bainbridge, Catherine C Cowie, Franklyn Gonzalez, Howard J Hoffman, Elizabeth Dinces, Jeremiah Stamler, Karen J Cruickshanks
AIM: The aim was to examine risk factors for hearing impairment among Hispanic/Latino adults with diabetes. METHODS: Findings are based on 3384 participants aged 18-76 years with diagnosed or previously undetected diabetes who completed audiometric testing as part of the Hispanic Community Health Study/Study of Latinos. We defined hearing impairment as the pure-tone average (PTA) >25 decibels hearing level [dB HL] of pure-tone thresholds at high frequencies (3000, 4000, 6000, and 8000 Hz) in the worse ear and defined a second hearing impairment outcome with the additional requirement of PTA >25 dB HL of low/mid-frequency (500, 1000, and 2000 Hz) thresholds in the worse ear...
December 2016: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/28239474/predictive-value-of-sperm-deoxyribonucleic-acid-dna-fragmentation-index-in-male-infertility
#3
Budi Wiweko, Pramety Utami
BACKGROUND: Recently, damage to the sperm DNA has been studied as it is associated with reduced fertilization rates, embryo quality, and pregnancy rates, also higher rates of spontaneous miscarriage. OBJECTIVE: To develop a diagnostic method in predicting male infertility. MATERIAL AND METHODS: The design of this study is cross-sectional. Data were retrieved from medical records of Yasmin IVF Clinic Dr. Cipto Mangunkusumo General Hospital and Daya Medika Infertility Clinic from January to December 2015...
2017: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/28238629/apolipoprotein-a1-rs5070-a-g-polymorphism-with-stroke-subtypes-in-taiwan
#4
Li-Chi Hsu, Tsong-Hai Lee
BACKGROUND: Apolipoprotein A1 (ApoA1) is a structural protein of high-density lipoprotein cholesterol; ApoA1 is involved in lipid and cholesterol metabolism. This study evaluated the association of ApoA1 polymorphism (rs5070) with different stroke subtypes in Taiwanese individuals. METHODS: A total of 2139 cases, including 614 controls and 708 large artery atherosclerosis (LAA), 377 small-vessel occlusion, and 440 hypertensive intracranial hemorrhage cases, were enrolled in this study...
February 23, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28238515/factors-influencing-hospital-stay-for-pulmonary-embolism-a-cohort-study
#5
Nuria Rodríguez-Núñez, Alberto Ruano-Raviña, Romina Abelleira, Lucía Ferreiro, Adriana Lama, Francisco J González-Barcala, Antonio Golpe, María E Toubes, José M Álvarez-Dobaño, Luis Valdés
INTRODUCTION: The aim of this study was to identify factors influencing hospital stay due to pulmonary embolism. METHODS: We performed a retrospective cohort study of patients hospitalized between 2010 and 2015. Patients were identified using information recorded in hospital discharge reports (ICD-9-CM codes 415.11 and 415.19). RESULTS: We included 965 patients with a median stay of 8 days (IQR 6-13 days). Higher scores on the simplified Pulmonary Embolism Severity Index (sPESI) were associated with increased probability of longer hospital stay...
February 23, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28238482/effect-of-weight-loss-on-puberty-onset-in-overweight-children
#6
Thomas Reinehr, Christina Bosse, Nina Lass, Juliane Rothermel, Caroline Knop, Christian Ludwig Roth
OBJECTIVE: To assess the impact of weight changes on the onset of puberty in overweight children. STUDY DESIGN: We evaluated the timing of puberty onset in 160 prepubertal overweight children (aged 11.2 ± 1.0 years) depending on the changes of their weight status in a 1-year lifestyle intervention. We determined body mass index (BMI), pubertal stage, luteinizing hormone (LH), follicle-stimulating hormone, insulin-like growth factor (IGF)-1, insulin-like growth factor binding protein-3, insulin resistance index homeostatic model assessment, and serum gonadotropins at baseline and 1 year later...
February 24, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28238293/the-weighting-is-the-hardest-part-on-the-behavior-of-the-likelihood-ratio-test-and-the-score-test-under-a-data-driven-weighting-scheme-in-sequenced-samples
#7
Camelia C Minică, Giulio Genovese, Christina M Hultman, René Pool, Jacqueline M Vink, Michael C Neale, Conor V Dolan, Benjamin M Neale
Sequence-based association studies are at a critical inflexion point with the increasing availability of exome-sequencing data. A popular test of association is the sequence kernel association test (SKAT). Weights are embedded within SKAT to reflect the hypothesized contribution of the variants to the trait variance. Because the true weights are generally unknown, and so are subject to misspecification, we examined the efficiency of a data-driven weighting scheme. We propose the use of a set of theoretically defensible weighting schemes, of which, we assume, the one that gives the largest test statistic is likely to capture best the allele frequency-functional effect relationship...
February 27, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28237520/smoking-as-a-risk-factor-for-breast-reduction-an-analysis-of-13-503-cases
#8
Jeffery S Hillam, Emily A Borsting, Jimmy H Chim, Seth R Thaller
BACKGROUND: Reduction mammaplasty is one of the most common reconstructive procedures performed by plastic surgeons. Over 100,000 procedures are performed annually. Although important for relieving the painful symptoms associated with macromastia, complication rates of this procedure are not insignificant. They are reported in up to half the cases. Reported risk factors for adverse outcomes include obesity, preoperative wound infection, and advanced American Society of Anesthesiologists status...
January 16, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28237380/newborn-dried-blood-spot-polymerase-chain-reaction-to-identify-infants-with-congenital-cytomegalovirus-associated-sensorineural-hearing-loss
#9
Shannon A Ross, Amina Ahmed, April L Palmer, Marian G Michaels, Pablo J Sánchez, Audra Stewart, David I Bernstein, Kristina Feja, Karen B Fowler, Suresh B Boppana
OBJECTIVE: To determine the utility of dried blood spot (DBS) polymerase chain reaction (PCR) in identifying infants with cytomegalovirus (CMV) infection-associated sensorineural hearing loss (SNHL). STUDY DESIGN: Newborns at 7 US hospitals between March 2007 and March 2012 were screened for CMV by saliva rapid culture and/or PCR. Infected infants were monitored for SNHL during the first 4 years of life to determine sensitivity, specificity, and positive and negative likelihood ratios of DBS PCR for identifying CMV-associated SNHL...
February 22, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28236299/development-of-the-platelet-efficacy-score-pescore-to-predict-the-efficacy-of-platelet-transfusion-in-oncohematologic-patients
#10
Anna Quaglietta, Maura Di Saverio, Giuseppe Lucisano, Patrizia Accorsi, Antonio Nicolucci
BACKGROUND: Despite the prophylactic use of platelet transfusion, hemorrhagic complications still represent an important cause of morbidity and mortality in patients with hematologic malignancies. Patient-related factors and characteristics of the transfused product can affect transfusion efficacy. STUDY DESIGN AND METHODS: The aim of this study was to develop and validate the Platelet Efficacy Score (PEscore), based on patient and product characteristics, to predict the likelihood of a satisfactory platelet transfusion (absolute increment ≥10...
February 24, 2017: Transfusion
https://www.readbyqxmd.com/read/28236271/glucagon-like-peptide-1-receptor-agonist-treatment-attributes-important-to-injection-experienced-patients-with-type-2-diabetes-mellitus-a-preference-study-in-germany-and-the-united-kingdom
#11
Lei Qin, Stephanie Chen, Emuella Flood, Alka Shaunik, Beverly Romero, Marie de la Cruz, Cynthia Alvarez, Susan Grandy
INTRODUCTION: This study assessed the relative importance of treatment-related attributes in influencing patient preferences for glucagon-like peptide-1 receptor agonists (GLP-1RAs) among injection-experienced type 2 diabetes mellitus (T2DM) patients in Germany and the United Kingdom. METHODS: T2DM patients experienced with injecting once-weekly (QW) exenatide or once-daily (QD) liraglutide completed an online discrete-choice experiment (DCE) survey. Patients chose between hypothetical blinded treatment profiles reflecting attributes of GLP-1RAs...
February 24, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28236025/incremental-diagnostic-quality-gain-of-cta-over-v-q-scan-in-the-assessment-of-pulmonary-embolism-by-means-of-a-wells-score-bayesian-model-results-from-the-acdc-collaboration
#12
Laila Cochon, Kaitlin McIntyre, José M Nicolás, Amado Alejandro Baez
OBJECTIVE: Our objective was to evaluate the diagnostic value of computed tomography angiography (CTA) and ventilation perfusion (V/Q) scan in the assessment of pulmonary embolism (PE) by means of a Bayesian statistical model. METHODS: Wells criteria defined pretest probability. Sensitivity and specificity of CTA and V/Q scan for PE were derived from pooled meta-analysis data. Likelihood ratios calculated for CTA and V/Q were inserted in the nomogram. Absolute (ADG) and relative diagnostic gains (RDG) were analyzed comparing post- and pretest probability...
February 24, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28235980/galectin-3-as-a-marker-for-clinical-prognosis-and-cardiac-remodeling-in-acute-heart-failure
#13
R I Lala, D Lungeanu, D Darabantiu, L Pilat, M Puschita
BACKGROUND: Galectin-3 has been reported as a mediator of heart failure (HF) development and progression. Most studies, however, have been conducted on patients with chronic HF rather than acute HF (AHF). The aim of this study was to confirm galectin-3 as a prognostic marker in subjects with AHF and to investigate its possible relationship with left ventricular (LV) remodeling. METHODS: A total of 69 patients hospitalized with a primary diagnosis of AHF were followed up for 18 months...
February 24, 2017: Herz
https://www.readbyqxmd.com/read/28231348/association-between-bone-graft-volume-and-maxillary-sinus-membrane-elevation-height
#14
Tetsuya Sonoda, Takehiro Harada, Nobuyuki Yamamichi, Alberto Monje, Hom-Lay Wang
PURPOSE: Maxillary sinus augmentation via crestal approach has been advocated as an alternative approach for sinus membrane elevation. Presently, no study has examined the relationship between the amount of bone grafting material placed and the final sinus membrane elevation height. Therefore, the present study was aimed at investigating the extent of sinus membrane elevation height depending on the amount of bone grafting material inserted as well as three-dimensionally assessing the likelihood of membrane perforation during membrane elevation...
February 23, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28230661/predicting-progression-in-barrett-s-esophagus-development-and-validation-of-the-barrett-s-esophagus-assessment-of-risk-score-bear-score
#15
Craig S Brown, Brittany Lapin, Jay L Goldstein, John G Linn, Mark S Talamonti, Joann Carbray, Michael B Ujiki
OBJECTIVE: To develop and validate a scoring tool capable of accurately predicting which patients with Barrett's esophagus (BE) will progress to dysplasia and/or esophageal adenocarcinoma. BACKGROUND: Endoscopic therapies have emerged capable of eradicating BE with high efficacy and low complication rates, but which patients should receive treatment is still debated. Current knowledge of risk factors is insufficient to allow for the accurate prediction of which patients will progress to dysplasia or adenocarcinoma...
February 22, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28230640/disparities-in-waitlist-and-posttransplantation-outcomes-in-liver-transplant-registrants-and-recipients-18-24-years-old-analysis-of-the-unos-database
#16
Noelle H Ebel, Evelyn K Hsu, Kristin Berry, Simon P Horslen, George N Ioannou
BACKGROUND: We evaluated liver transplantation waitlist and posttransplantation outcomes in 18-24 year olds compared to both younger (0-17 year old) and older (25-34 year old) registrants and recipients. METHODS: Utilizing national data from the United Network for Organ Sharing, competing risk, Cox regression and Kaplan-Meier analyses were performed on first-time liver transplant registrants (n=13,979) and recipients (n=8,718) ages 0-34 years old between 2002 to 2015...
February 22, 2017: Transplantation
https://www.readbyqxmd.com/read/28230457/comparative-effectiveness-of-rapid-acting-insulins-in-adults-with-diabetes
#17
Patrick N Racsa, Yunus Meah, Jeffrey J Ellis, Kimberly R Saverno
BACKGROUND: Although there are a variety of insulin products and new delivery modalities available, the absence of direct clinical and economic comparisons can make treatment planning and formulary decision making difficult. Direct comparisons between insulin aspart and insulin lispro from a large heterogeneous population are not available. OBJECTIVE: To assess differences in clinical outcomes, medication adherence, utilization, and total health care costs between aspart and lispro and vial versus pen modalities for administering these short-acting insulin analogs...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230044/a-meta-analysis-to-evaluate-the-diagnostic-value-of-dual-time-point-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-for-diagnosis-of-pulmonary-nodules
#18
Ming Zhao, Yongfu Ma, Bo Yang, Yuqi Wang
OBJECTIVES: This meta-analysis aimed at evaluating the efficacy of dual-time-point (DTP) F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) in diagnosing pulmonary nodules. METHODS: Using computer and manual search, the current research about the efficacy of DTP F-FDG PET/CT in diagnosing pulmonary nodules was collected. According to the evaluation criteria of Quality Assessment of Diagnostic Accuracy Studies Scale, the data from 13 studies were analyzed by Meta-DiSc software, and the sensitivity (Sen), specificity (Spe), diagnostic odds ratios (DOR), positive likelihood ratios (LR+), and negative likelihood ratios (LR-) were summarized...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230035/a-meta-analysis-of-contrast-enhanced-ultrasound-for-small-hepatocellular-carcinoma-diagnosis
#19
Huadong Deng, Hongwei Shi, Jianming Lei, Yan Hu, Gang Li, Chaojun Wang
OBJECTIVE: To discuss the efficacy of contrast-enhanced ultrasound (CEUS) for diagnosis of small hepatocellular carcinoma (HCC) by pooling the open published data. METHODS: A comprehensive publication electronic search was performed by reviewers in the databases of PubMed, Embase, Web of Science, and China National Knowledge Infrastructure. The open published studies about CEUS for small HCC diagnosis were collected. The sensitivity, specificity, positive likelihood ratio (+LR), negative likelihood ratio (-LR), and diagnostic odds ratio (DOR) were pooled by stata 12...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230031/serum-pro-gastrin-releasing-peptide-in-diagnosis-of-small-cell-lung-cancer-a-meta-analysis
#20
Hongyuan Wang, Junfeng Qian
OBJECTIVE: The purpose of this study was to assess the diagnostic sensitivity and specificity for serum pro-gastrin-releasing peptide (Pro-GRP) in diagnosis of small cell lung cancer (SCLC) through pooling all the open published data. MATERIALS AND METHODS: Databases of PubMed, Cochrane, ISI Web of Knowledge, and CNKI were electronic, searched by two reviewers to find the diagnostic study serum Pro-GRP in diagnosis of SCLC. The diagnostic sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the receiver operating characteristic (ROC) were calculated by Med DiSc1...
December 2016: Journal of Cancer Research and Therapeutics
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