keyword
MENU ▼
Read by QxMD icon Read
search

neuropsychiatric manifestation

keyword
https://www.readbyqxmd.com/read/30642853/fulminant-guillain-barr%C3%A3-syndrome-in-a-patient-with-systemic-lupus-erythematosus
#1
Eric Anthony Coomes, Hourmazd Haghbayan, Jenna Spring, Sangeeta Mehta
A 45-year-old man with a history of systemic lupus erythematosus presented with progressive weakness and areflexia. Electromyogram revealed reduced motor and sensory amplitudes without demyelinating features. He was clinically diagnosed with the acute motor and sensory axonal neuropathy variant of Guillain-Barré syndrome. Despite intravenous immunoglobulin therapy, he deteriorated with loss of all voluntary motor function and cranial nerve reflexes. Concomitant investigations revealed class V lupus nephritis...
January 14, 2019: BMJ Case Reports
https://www.readbyqxmd.com/read/30633946/the-psychomotor-vigilance-task-role-in-the-diagnosis-of-hepatic-encephalopathy-and-relationship-with-driving-ability
#2
Chiara Formentin, Michele De Rui, Mirko Zoncapè, Silvia Ceccato, Lisa Zarantonello, Marco Senzolo, Patrizia Burra, Paolo Angeli, Piero Amodio, Sara Montagnese
BACKGROUND & AIMS: Hepatic Encephalopathy (HE) is a syndrome of decreased vigilance, and has been associated with impaired driving ability. The aim of this study was to evaluate the Psychomotor Vigilance Task (PVT), which is used to assess both vigilance and driving ability, in a group of patients with cirrhosis and varying degree of HE. METHODS: 145 patients (120 males, 59±10 years, MELD 13±5) underwent the PVT; a subgroup of 117 completed a driving questionnaire; a subgroup of 106 underwent the Psychometric Hepatic Encephalopathy Score (PHES) and the electroencephalogram (EEG), based on which, plus a clinical evaluation, they were classed as unimpaired (n=51), minimal (n=35) or mild overt HE (n=20)...
January 8, 2019: Journal of Hepatology
https://www.readbyqxmd.com/read/30632405/epidemiology-characterization-and-diagnosis-of-neuropsychiatric-events-in-systemic-lupus-erythematosus
#3
Jaqueline Cristina de Amorim, Renan Bazuco Frittoli, Danilo Pereira, Mariana Postal, Sergio San Juan Dertkigil, Fabiano Reis, Lilian Tl Costallat, Simone Appenzeller
Neuropsychiatric systemic lupus erythematosus (NPSLE) is characterized by a heterogeneity of clinical manifestations. The absence of diagnostic criteria and the lack of clinical trials is a challenge in clinical practice. Areas covered: A literature review was performed to describe epidemiology, characterization (clinical, immunological and imaging), diagnosis and treatment of NPSLE. Classification criteria have been the first step towards a uniform definition. More recently, different attribution models have been developed to help to determine if the NP event is due to SLE...
January 11, 2019: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/30632019/psychiatric-and-cognitive-symptoms-associated-with-niemann-pick-type-c-disease-neurobiology-and-management
#4
REVIEW
Thomas Rego, Sarah Farrand, Anita M Y Goh, Dhamidhu Eratne, Wendy Kelso, Simone Mangelsdorf, Dennis Velakoulis, Mark Walterfang
Niemann-Pick disease type C (NPC) is a lysosomal storage disorder that presents with a spectrum of clinical manifestations from infancy and childhood or in early or mid-adulthood. Progressive neurological symptoms including ataxia, dystonia and vertical gaze palsy are a hallmark of the disease, and psychiatric symptoms such as psychosis and mood disorders are common. These latter symptoms often present early in the course of NPC and thus these patients are often diagnosed with a major psychotic or affective disorder before neurological and cognitive signs present and the diagnosis is revised...
January 10, 2019: CNS Drugs
https://www.readbyqxmd.com/read/30631338/neuropsychiatric-manifestations-of-cognitively-advanced-idiopathic-normal-pressure-hydrocephalus
#5
Robert Mathew, Sauda Pavithran, P Byju
Background: Neuropsychiatric manifestations of patients with idiopathic normal pressure hydrocephalus (iNPH) have not been studied in a systematic way. Aim: To study the spectrum of neuropsychiatric abnormalities in patients with iNPH. Patient Selection and Evaluation: Patients attending 3 different tertiary care centers during three consecutive time periods spanning from 2010 to 2015 were analyzed for neuropsychiatric manifestations. Patients diagnosed as having probable or possible iNPH as per the consensus criteria were included in the study...
September 2018: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/30612913/cm-pf-deep-brain-stimulation-and-the-long-term-management-of-motor-and-psychiatric-symptoms-in-a-case-of-tourette-syndrome
#6
Massimo Marano, Simone Migliore, Ferdinando Squitieri, Angelo Insola, Eugenio Scarnati, Paolo Mazzone
Tourette syndrome is a rare neuropsychiatric disorder affecting the cortico-striato-thalamo-cortical system. The disease manifests in childhood with tics and various psychiatric comorbidities. Cases of refractory Tourette syndrome are valuable candidates for functional neurosurgery. The thalamic centromedian-parafascicular complex is an experimental target that shows a promising role in Tourette syndrome deep brain stimulation, due to pathophysiologic evidences. We have shown on a long term follow-up, that thalamic deep brain stimulation, targeted on the centromedian-parafascicular complex, could modulate motor (i...
January 3, 2019: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/30599666/rapid-rate-on-quasi-speech-tasks-in-the-semantic-variant-of-primary-progressive-aphasia-a-non-motor-phenomenon
#7
Rene L Utianski, Hugo Botha, Joseph R Duffy, Heather M Clark, Peter R Martin, Alissa M Butts, Mary M Machulda, Jennifer L Whitwell, Keith A Josephs
This study examined the rate of producing alternating motion rates, sequential motion rates (SMRs), and repeated words in 27 individuals with the semantic variant of Primary Progressive Aphasia (svPPA). Only the rate of producing SMRs was significantly elevated in svPPA compared to controls. This may be associated with concomitant neuropsychiatric symptoms in svPPA, as correlation analysis showed a relationship between increased SMR rate and the Neuropsychiatric Inventory Questionnaire, which documented anxiety and disinhibition...
December 2018: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/30584474/identification-of-levels-of-serum-amyloid-a-and-apolipoprotein-a1-in-serum-proteomic-analysis-of-neuropsychiatric-systemic-lupus-erythematosus-patients
#8
Nancy P Duarte-Delgado, Tania P Lujan, Álvaro Arbeláez-Cortés, Jenny García-Valencia, Adriana Zapata, Mauricio Rojas, Mauricio Restrepo-Escobar, Gloria Vásquez, Blanca L Ortiz-Reyes
Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) has multiple pathogenic mechanisms that cause diverse manifestations and whose diagnosis is challenging because of the absence of appropriate diagnostic tests. In the present study the application of proteomics using two-dimensional electrophoresis (2D) and mass spectrometry (MS) allowed the comparison of the protein profile of the serum low and high abundance protein fractions of NPSLE patients (NPSLE group) and SLE without neuropsychiatric syndromes (SLE group), Neuropsychiatric syndromes not associated with SLE (NPnoSLE groups), and healthy controls (CTRL group)...
2018: Autoimmune Diseases
https://www.readbyqxmd.com/read/30581397/a-conscious-resting-state-fmri-study-in-sle-patients-without-major-neuropsychiatric-manifestations
#9
Shuang Liu, Yuqi Cheng, Zhongqi Xie, Aiyun Lai, Zhaoping Lv, Yueyin Zhao, Xiufeng Xu, Chunrong Luo, Hongjun Yu, Baoci Shan, Lin Xu, Jian Xu
Neuropsychiatric systemic lupus erythematosus (NPSLE) is one of the main causes of death in patients with systemic lupus erythematosus (SLE). Signs and symptoms of NPSLE are heterogeneous, and it is hard to diagnose, and treat NPSLE patients in the early stage. We conducted this study to explore the possible brain activity changes using resting state functional magnetic resonance imaging (rs-fMRI) in SLE patients without major neuropsychiatric manifestations (non-NPSLE patients). We also tried to investigate the possible associations among brain activity, disease activity, depression, and anxiety...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/30572142/an-evolving-redefinition-of-autoimmune-encephalitis
#10
REVIEW
Susanna Esposito, Nicola Principi, Paolo Calabresi, Donato Rigante
Autoimmune encephalitis encompasses a wide variety of protean pathologic processes associated with the presence of antibodies against neuronal intracellular proteins, synaptic receptors, ion channels and/or neuronal surface proteins. This type of encephalitis can also involve children with complex patterns of seizures and unexpected behavioural changes, which jeopardize their prompt recognition and treatment. Many epidemiological studies have shown that numerous immune-based forms of encephalitis can be encountered, almost surpassing the rate of postinfectious encephalitides...
December 18, 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/30567600/primary-respiratory-disease-in-patients-with-systemic-lupus-erythematosus-data-from-the-spanish-rheumatology-society-lupus-registry-relesser-cohort
#11
Javier Narváez, Helena Borrell, Fernando Sánchez-Alonso, Iñigo Rúa-Figueroa, Francisco Javier López-Longo, María Galindo-Izquierdo, Jaime Calvo-Alén, Antonio Fernández-Nebro, Alejandro Olivé, José Luis Andreu, Víctor Martínez-Taboada, Joan Miquel Nolla, José María Pego-Reigosa
BACKGROUND: The purpose of this study was to assess the prevalence, associated factors, and impact on mortality of primary respiratory disease in a large systemic lupus erythematosus (SLE) retrospective cohort. METHODS: All adult patients in the RELESSER-TRANS (Registry of Systemic Lupus Erythematosus Patients of the Spanish Society of Rheumatology [SER], cross-sectional phase) registry were retrospectively investigated for the presence of primary pleuropulmonary manifestations...
December 19, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/30564579/laboratory-and-neuroimaging-biomarkers-in-neuropsychiatric-systemic-lupus-erythematosus-where-do-we-stand-where-to-go
#12
REVIEW
César Magro-Checa, Gerda M Steup-Beekman, Tom W Huizinga, Mark A van Buchem, Itamar Ronen
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multi-systemic involvement. Nervous system involvement in SLE leads to a series of uncommon and heterogeneous neuropsychiatric (NP) manifestations. Current knowledge on the underlying pathogenic processes and their subsequent pathophysiological changes leading to NP-SLE manifestations is incomplete. Several putative laboratory biomarkers have been proposed as contributors to the genesis of SLE-related nervous system damage. Alongside the laboratory biomarkers, several neuroimaging tools have shown to reflect the nature of tissue microstructural damage associated with SLE, and thus were suggested to contribute to the understanding of the pathophysiological changes and subsequently help in clinical decision making...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/30564454/systemic-lupus-erythematosus-state-of-the-art-on-clinical-practice-guidelines
#13
REVIEW
Farah Tamirou, Laurent Arnaud, Rosaria Talarico, Carlo Alberto Scirè, Tobias Alexander, Zahir Amoura, Tadej Avcin, Alessandra Bortoluzzi, Ricard Cervera, Fabrizio Conti, Alain Cornet, Hervé Devilliers, Andrea Doria, Micol Frassi, Micaela Fredi, Marcello Govoni, Frederic Houssiau, Ana Lladò, Carla Macieira, Thierry Martin, Laura Massaro, Maria Francisca Moraes-Fontes, Cristina Pamfil, Sabrina Paolino, Chiara Tani, Sander W Tas, Maria Tektonidou, Angela Tincani, Ronald F Van Vollenhoven, Stefano Bombardieri, Gerd Burmester, Fonseca João Eurico, Ilaria Galetti, Eric Hachulla, Ulf Mueller-Ladner, Matthias Schneider, Vanessa Smith, Maurizio Cutolo, Marta Mosca, Nathalie Costedoat-Chalumeau
Systemic lupus erythematosus (SLE) is the paradigm of systemic autoimmune diseases characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing-remitting course. The aim of the present work was to identify current available clinical practice guidelines (CPGs) for SLE, to provide their review and to identify physicians' and patients' unmet needs. Twenty-three original guidelines published between 2004 and 2017 were identified. Many aspects of disease management are covered, including global disease management, lupus nephritis and neuropsychiatric involvement, management of pregnancies, vaccinations and comorbidities monitoring...
2018: RMD Open
https://www.readbyqxmd.com/read/30562773/-multidisciplinary-classification-of-magnetic-resonance-imaging-features-of-neuropsychiatric-lupus
#14
J Y Chang, M Zheng, Y Liu, R Liu, J F Zhang, X L Deng
OBJECTIVE: To investigate the clinical correlation between the manifestations of neuropsychiatric lupus (NPSLE) and brain magnetic resonance imaging (MRI). METHODS: Retrospective analysis of 65 neuropsychiatric lupus patients with brain MRI and clinical data from Peking University Third Hospital from January 2006 to October 2016, which was classified by rheumatologist, neurologists, and radiologists based on their brain MRI findings. The correlation between brain MRI findings and clinical manifestations was analyzed...
December 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/30562772/-clinical-and-immunological-characteristics-of-patients-with-systemic-lupus-erythematosus-in-tibet-plateau-china
#15
J Yang, H H Yao, X D Mo, Z Luo, Yangjin Baima
OBJECTIVE: To describe the clinical, immunological characteristics and organ involvement of patients with systemic lupus erythematosus (SLE) in Tibet plateau, China. METHODS: We retrospectively investigated 70 patients admitted in the Tibet Autonomous Region People's Hospital between May 2014 and April 2016. In the study, 120 hospitalized patients with SLE from the Department of Rheumatology and Immunology of the Peking University People's Hospital were randomly selected as the control (plain) group...
December 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/30558047/anti-n-methyl-d-aspartate-receptor-encephalitis-a-case-report
#16
Hua Li, Yan-Ke Guo, Ying-Lin Cui, Tao Peng
RATIONALE: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an auto-immune and paraneoplastic encephalitis with prominent neuropsychiatric manifestations. The N-methyl-D-aspartate receptor is located in the forebrain and hippocampus and plays a role in learning and memory. PATIENT CONCERNS: A 29-year-old female patient with anti-NMDAR encephalitis, was reported and we also reviewed the literature and summarised the characteristics of the cases. DIAGNOSES: In the present study, we reported 1 patient with anti-NMDAR encephalitis diagnosed by the detection of anti-NMDAR antibodies in serum and cerebrospinal fluid (CSF)...
December 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30546250/investigating-the-influence-of-ubiquinone-blood-level-on-the-abilities-of-children-with-specific-learning-disorder
#17
Ehab Ragaa Abdelraouf, Ayman Kilany, Adel F Hashish, Ola Hosny Gebril, Suzette Ibrahim Helal, Haytham Mohamad Hasan, Neveen Hassan Nashaat
Background: Ubiquinone has antioxidant properties and has been linked to cognitive performance in some neuropsychiatric disorders. Its role in specific learning disorder manifestations has not been previously investigated. Therefore, the aim of this study was to measure the blood levels of ubiquinone in a group of children with specific learning disorder in comparison to typically developing children and to investigate the correlation between ubiquinone levels in children with specific learning disorder and some of their intellectual capabilities, reading, spelling and writing performance...
2018: The Egyptian journal of neurology, psychiatry and neurosurgery
https://www.readbyqxmd.com/read/30537912/deficits-in-emotion-recognition-as-markers-of-frontal-behavioral-dysfunction-in-amyotrophic-lateral-sclerosis
#18
Aldrin Pedroza Martins, Laura de Godoy Rousseff Prado, Patricia Lillo, Eneida Mioshi, Antônio Lúcio Teixeira, Leonardo Cruz de Souza
OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with prominent motor symptoms. Patients with ALS may also manifest frontal behavior symptoms and cognitive decline, including impairment in facial emotion recognition. The authors aimed to investigate whether deficits in emotion recognition were associated with frontal behavior symptoms in ALS. METHODS: Participants were patients with probable or definite sporadic ALS (N=21; male:female ratio, 11:10; median age, 62 years; median disease duration, 3 years) and age-matched and education-matched healthy control subjects (N=25; male:female ratio, 14:11; median age, 61 years)...
December 12, 2018: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/30527288/the-impact-of-psychiatric-symptoms-on-tuberous-sclerosis-complex-and-utilization-of-mental-health-treatment
#19
Kate E Mowrey, Myla Ashfaq, Deborah A Pearson, Syed S Hashmi, Steven L Roberds, Laura S Farach, Hope Northrup
BACKGROUND: Tuberous sclerosis complex (TSC) is a multisystem, neurocutaneous disorder with a spectrum of TSC-associated neuropsychiatric disorders. The most common neuropsychiatric manifestations in the pediatric and adult populations are cognitive concerns, depression, and anxiety. Previous research suggests that while 90% of individuals with TSC have some TSC-associated neuropsychiatric disorders features, only 20% receive treatment, leading to a 70% treatment gap. METHODS: This web-based study used validated measures in conjunction with researcher-designed questions to evaluate perception of disease severity, presence of anxiety and depression, and the utilization and barriers toward mental health services among adults with TSC...
November 3, 2018: Pediatric Neurology
https://www.readbyqxmd.com/read/30522973/structural-white-matter-networks-in-myotonic-dystrophy-type-1
#20
Maud van Dorst, Kees Okkersen, Roy P C Kessels, Frederick J A Meijer, Darren G Monckton, Baziel G M van Engelen, Anil M Tuladhar, Joost Raaphorst
The myriad of neuropsychiatric manifestations reported in myotonic dystrophy type 1 may have its origin in alterations of complex brain network interactions at the structural level. In this study, we tested the hypothesis that altered white matter microstructural integrity and network organisation were present in a cohort of individuals with DM1 compared to unaffected controls, which was expected to be associated with CNS related disease manifestations of DM1. We performed a cross-sectional neuropsychological assessment and brain MRI in 25 myotonic dystrophy type 1 (DM1) patients and 26 age, sex and educational level matched unaffected controls...
November 28, 2018: NeuroImage: Clinical
keyword
keyword
49492
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"