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rhinosinusitis antibiotics

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https://www.readbyqxmd.com/read/29775027/-clinical-research-of-different-characteristics-of-fungal-ball-sinusitis
#1
M J Wang, B Zhou, Y C Li, S J Cui, Q Huang
Objective: The aim of this study is to investigate the clinical features of different subtypes of fungal ball sinusitis. Method: Four hundred and forty-nine cases with fungal ball rhinosinusitis (FBS) were involved in this retrospective analysis. The clinical features including symptoms, signs, and imaging scans, pathological results were all collected for each patient and the patients were classified into different subtypes according to these clinical features and the follow-up treatment. Result: In this retrospective study, 449 patients who diagnosed with fungal ball sinusitis were involved...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29771095/-a-progress-of-macrolides-therapy-for-chronic-rhinosinusitis
#2
REVIEW
S Shen, C S Wang
Macrolides are a type of antibiotics with macrocyclic lactone ring, which have been commonly used in the treatment of diffuse panbronchiolitis, chronic obstructive pulmonary disease, bronchial asthma, cystic fibrosis and other diseases. Macrolides not only have effect on antibacterial, but also effect on anti-inflammatory and immunoregulation. Chronic rhinosinusitis (CRS) is a common disease entity of infectious and inflammatory diseases that involved in nasal cavity and nasal sinuses, with various clinical phenotypes...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29759028/reciprocal-predictive-accuracy-of-sinonasal-symptom-severity-nasal-endoscopy-and-frequency-of-past-chronic-rhinosinusitis-exacerbations
#3
Marlene M Speth, Robert A Gaudin, Lloyd P Hoehle, Katie M Phillips, David S Caradonna, Stacey T Gray, Ahmad R Sedaghat
Objective We sought to determine whether chronic rhinosinusitis (CRS) symptom severity, endoscopic exam findings, and acute exacerbation of CRS (AECRS) frequency-all important and distinct clinical manifestations of CRS-would be predictive of each other and, therefore, inform when further assessment of each other metric should be pursued. Study Design Cross-sectional cohort study. Setting Tertiary academic rhinology clinic. Subjects and Methods In total, 241 patients with CRS were prospectively recruited and completed the 22-item Sinonasal Outcome Test (SNOT-22) to reflect CRS symptom severity...
May 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29731100/endotype-driven-care-pathways-in-patients-with-chronic-rhinosinusitis
#4
REVIEW
Claus Bachert, Nan Zhang, Peter W Hellings, Jean Bousquet
Chronic rhinosinusitis (CRS) has been differentiated clinically into CRS without nasal polyps and CRS with nasal polyps, with both forms subjected to glucocorticosteroid and antibiotic treatments and, if not successful, to nasal and sinus surgery tailored to endoscopic and computed tomographic scan findings. The elaboration of endotypes based on pathomechanisms involving different immune responses offers new possibilities in terms of prediction of prognosis and risks and sophisticated guidance in personalized pharmacotherapy, surgical approaches, and innovative treatment approaches in the CRS field with various biologics...
May 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29719129/adult-acute-rhinosinusitis-guidelines-worldwide-similarities-and-disparities
#5
Ofer Gluck, Tal Marom, Shay Shemesh, Sharon Ovnat Tamir
BACKGROUND: Acute rhinosinusitis (ARS) is a common respiratory infection that poses a major public healthcare burden with respect to antibiotic consumption and related morbidity. Position statements and national ARS guidelines have been published worldwide, aiming to define diagnostic criteria and outline treatment options. Our objective was to analyze the similarities and disparities between such guidelines. METHODS: We conducted an electronic database search for ARS guidelines using relevant keywords between January 1, 1989, through December 31, 2017...
May 2, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29696011/topical-colloidal-silver-for-the-treatment-of-recalcitrant-chronic-rhinosinusitis
#6
Mian L Ooi, Katharina Richter, Catherine Bennett, Luis Macias-Valle, Sarah Vreugde, Alkis J Psaltis, Peter-John Wormald
Background: The management of recalcitrant chronic rhinosinusitis (CRS) is challenged by difficult-to-treat polymicrobial biofilms and multidrug resistant bacteria. This has led to the search for broad-spectrum non-antibiotic antimicrobial therapies. Colloidal silver (CS) has significant antibiofilm activity in vitro and in vivo against S. aureus, MRSA , and P. aeruginosa . However, due to the lack of scientific efficacy, it is only currently used as an alternative medicine. This is the first study looking at the safety and efficacy of CS in recalcitrant CRS...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29605347/diagnosis-and-management-of-pediatric-sinusitis-a-survey-of-primary-care-otolaryngology-and-urgent-care-providers
#7
Laurie Newton, Amanda Kotowski, Melissa Grinker, Robert Chun
OBJECTIVES: The aims of this project were two-fold: 1) To assess pediatric primary care (PCP), pediatric otolaryngology (ENT) and pediatric urgent care (UC) providers' perception of their adherence to the 2013 American Academy of Pediatrics (AAP) established guidelines for the diagnosis and management of acute bacterial rhinosinusitis (ABRS) in children 1-18 years old and 2) to assess the same providers' practice patterns in the diagnosis and management of pediatric chronic rhinosinusitis (PCRS)...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29588108/how-to-avoid-the-inappropriate-use-of-antibiotics-in-upper-respiratory-tract-infections-a-position-statement-from-an-expert-panel
#8
Otávio Bejzman Piltcher, Eduardo Macoto Kosugi, Eulalia Sakano, Olavo Mion, José Ricardo Gurgel Testa, Fabrizio Ricci Romano, Marco Cesar Jorge Santos, Renata Cantisani Di Francesco, Edson Ibrahim Mitre, Thiago Freire Pinto Bezerra, Renato Roithmann, Francini Greco Padua, Fabiana Cardoso Pereira Valera, José Faibes Lubianca Neto, Leonardo Conrado Barbosa Sá, Shirley Shizue Nagata Pignatari, Melissa Ameloti Gomes Avelino, Juliana Alves de Souza Caixeta, Wilma Terezinha Anselmo-Lima, Edwin Tamashiro
INTRODUCTION: Bacterial resistance burden has increased in the past years, mainly due to inappropriate antibiotic use. Recently it has become an urgent public health concern due to its impact on the prolongation of hospitalization, an increase of total cost of treatment and mortality associated with infectious disease. Almost half of the antimicrobial prescriptions in outpatient care visits are prescribed for acute upper respiratory infections, especially rhinosinusitis, otitis media, and pharyngotonsillitis...
February 25, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29573437/detection-of-bacteria-by-16s-rrna-pcr-and-sequencing-in-culture-negative-chronic-rhinosinusitis
#9
Abhilasha Karunasagar, Roshan Jalastagi, Ashok Naik, Praveen Rai
OBJECTIVE: Current studies on the association between bacteria and chronic rhinosinusitis (CRS) have relied solely on microbiological culture, which can sometimes be negative due to prior antibiotic therapy or lack of transport media. The objective of the study was to understand whether bacteria are associated with culture-negative cases. METHODS: We investigated 20 cases of CRS undergoing functional endoscopic sinus surgery by both culture and 16S rRNA gene polymerase chain reaction (PCR) followed by sequencing...
March 24, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29570529/surgical-treatment-of-rhinosinusitis-related-orbital-complications-factors-affecting-irreversible-blindness
#10
Onur Ismi, Yusuf Vayisoğlu, Kemal Koray Bal, Ilter Helvaci, Kemal Görür, Cengiz Ozcan
If left untreated, rhinosinusitis can rarely cause a devastating complication irreversible blindness (IB). Despite new technologies in endoscopic sinus surgery and use of new broad-spectrum antibiotics, IB outcome is still a problem for surgically treated orbital complication of paranasal sinus infection (OCPSI) patients, and factors leading to IB outcome are not actually known. The aim of this study was to assess the factors leading to the IB outcome for surgically treated OCPSI patients. Results of 25 surgically treated OCPSI patients in our clinic were combined with surgically treated OCPSI patients reported through the PubMed database search from the year 2007...
March 22, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29569338/gorilla-endoscopic-sinus-surgery-a-life-saving-collaboration-between-human-and-veterinary-medicine
#11
Greg E Davis, Fred M Baik, Robert M Liddell, Andrew G Ayars, Kelley R Branch, Paul S Pottinger, Allen D Hillel, Kelly Helmick, Darin Collins
BACKGROUND: Chronic rhinosinusitis is a common disease process in humans; however, in the primate population of gorillas, it has rarely been described. This case describes lifesaving sinus surgery on a critically ill gorilla performed by a human otolaryngology team in collaboration with the gorilla's veterinary medicine team. METHODS: The 35-year-old western silverback gorilla was treated for 3 months with aggressive medical therapy for a worsening sinus infection...
March 23, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29517429/treatment-of-mycotic-rhinosinusitis-in-a-bennett-s-wallaby-macropus-rufogriseus-using-topical-voriconazole-suspended-in-a-reverse-thermodynamic-pluronic-gel
#12
Josephine Bryk Rose, Sarah Davies, Kadie M Anderson, Graeme S Allan, Patricia M Dennis, Richard Malik
An approximately 4-yr-old female Bennett's wallaby ( Macropus rufogriseus) was evaluated for chronic left-sided facial swelling and nasal discharge. Computed tomography, endoscopy, biopsy, mycologic culture, and panfungal polymerase chain reaction were consistent with destructive mycotic rhinosinusitis. The patient's infection was treated with a long-term injectable antibiotic, oral antifungal therapy, and multiple intranasal infusions of voriconazole suspended in a reverse thermodynamic pluronic gel. This case represents the first documented case of mycotic rhinosinusitis in a macropod and underlines the importance of advanced cross-sectional imaging in the diagnosis, monitoring, and management of nasal cavity disease in zoo animals...
March 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29517178/the-effect-of-medical-treatments-on-the-bacterial-microbiome-in-patients-with-chronic-rhinosinusitis-a-pilot-study
#13
Ravi Jain, Michael Hoggard, Melissa Zoing, Yannan Jiang, Kristi Biswas, Michael W Taylor, Richard G Douglas
BACKGROUND: Antibiotics and corticosteroids are prescribed to patients with chronic rhinosinusitis (CRS) to reduce bacterial burden and mucosal inflammation. Unfortunately, clinical improvement is often short-lived and symptoms frequently recur following cessation of treatment. The impact of these systemic therapies on bacterial communities is not well understood. Improved knowledge of how medical therapies influence the intranasal ecosystem may allow for more effective prescribing and the development of more targeted treatments...
March 8, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29501308/prevalence-of-upper-respiratory-tract-infections-in-habitually-snoring-and-mouth-breathing-children
#14
Wojciech Kukwa, Christian Guilleminault, Magdalena Tomaszewska, Andrzej Kukwa, Antoni Krzeski, Ewa Migacz
OBJECTIVES: The aim of the study was to investigate the prevalence of upper respiratory tract infections (URI) - as indicated by rhinosinusitis (RS), ear infections (EI), and antibiotic consumption - in a general pediatric population and evaluate the relationship between these conditions and habitual snoring and mouth breathing during sleep. METHODS: A population-based cross-sectional study was performed in three medium-sized Polish cities from 2011 to 2015. RESULTS: 4837/6963 questionnaires (69...
April 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29490061/defining-the-appropriateness-and-inappropriateness-of-antibiotic-prescribing-in-primary-care
#15
David R M Smith, F Christiaan K Dolk, Koen B Pouwels, Morag Christie, Julie V Robotham, Timo Smieszek
Objectives: To assess the appropriateness of prescribing systemic antibiotics for different clinical conditions in primary care, and to quantify 'ideal' antibiotic prescribing proportions in conditions for which antibiotic treatment is sometimes but not always indicated. Methods: Prescribing guidelines were consulted to define the appropriateness of antibiotic therapy for the conditions that resulted in antibiotic prescriptions between 2013 and 2015 in The Health Improvement Network (THIN) primary care database...
February 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29490060/actual-versus-ideal-antibiotic-prescribing-for-common-conditions-in-english-primary-care
#16
Koen B Pouwels, F Christiaan K Dolk, David R M Smith, Julie V Robotham, Timo Smieszek
Objectives: Previous work based on guidelines and expert opinion identified 'ideal' prescribing proportions-the overall proportion of consultations that should result in an antibiotic prescription-for common infectious conditions. Here, actual condition-specific prescribing proportions in primary care in England were compared with ideal prescribing proportions identified by experts. Methods: All recorded consultations for common infectious conditions (cough, bronchitis, exacerbations of asthma or chronic obstructive pulmonary disease, sore throat, rhinosinusitis, otitis media, lower respiratory tract infection, upper respiratory tract infection, influenza-like illness, urinary tract infection, impetigo, acne, gastroenteritis) for 2013-15 were extracted from The Health Improvement Network (THIN) database...
February 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29476192/epos2012-has-better-specificity-compared-to-idsa2012-for-diagnosing-acute-bacterial-rhinosinusitis
#17
K Seresirikachorn, K Snidvongs, W Chitsuthipakorn, W Ruksakul, S Chusakul, J Kanjanaumporn, S Aeumjaturapat
BACKGROUND: Acute bacterial rhinosinusitis (ABRS) is a subtype of acute rhinosinusitis (ARS). To prevent excessive antibiotic prescribing, clinical criteria for diagnosing ABRS are presented in two major international guidelines from European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS2012) and the Infectious Diseases Society of America (IDSA2012). This study aims to assess accuracy of these criteria. METHODOLOGY: Patients with ARS were recruited. Clinical features were collected including discolored nasal discharge, facial pain, fever, double sickening, symptoms persisting longer than 10 days, and elevated serum C reactive protein (CRP) and erythrocyte sedimentation rate (ERS)...
February 24, 2018: Rhinology
https://www.readbyqxmd.com/read/29453018/-management-of-rhinosinusitis-in-primary-care
#18
N Gómez Gabaldón, C Manzanares Arnaiz, L Noguero Cánovas, J Juan Armas
Acute rhinosinusitis is an important health problem. Even though its frequency is not well documented in our country?, the economic burden it bears is not insignificant as it notably alters the quality of life of affected patients. Its diagnosis is generally clinical in nature, with further studies reserved only for the differential diagnoses of complications or tumour-like processes. The most frequent causes are viral infections, although Streptococcus pneumoniae and Haemophilus influenzae are the most commonly isolated bacterial agents...
February 13, 2018: Semergen
https://www.readbyqxmd.com/read/29450710/indicators-for-imaging-in-periorbital-cellulitis-secondary-to-rhinosinusitis
#19
Basel Jabarin, Ephraim Eviatar, Ofer Israel, Tal Marom, Haim Gavriel
PURPOSE: Our objective was to identify the clinical indicators for subperiosteal orbital abscess (SPOA) among patients who present with periorbital cellulitis secondary to rhinosinusitis, and to evaluate the need for performing a computerized tomography (CT) scan. METHODS: A retrospective cohort study of all patients admitted to our tertiary care emergency department between 2006 and 2014 was conducted. Included were healthy patients with acute periorbital cellulitis secondary to rhinosinusitis...
April 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29449345/antimicrobial-activity-of-a-novel-bioengineered-honey-against-non-typeable-haemophilus-influenzae-biofilms-an-in-vitro-study
#20
Rachel S Newby, Matthew Dryden, Raymond N Allan, Rami J Salib
The opportunistic pathogen non-typeable Haemophilus influenzae (NTHi) plays an important role in many chronic respiratory diseases including otitis media, chronic rhinosinusitis, cystic fibrosis and chronic obstructive pulmonary disease. Biofilm formation has been implicated in NTHi colonisation, persistence of infection and recalcitrance towards antimicrobials. There is therefore a pressing need for the development of novel treatment strategies that are effective against NTHi biofilm-associated diseases. SurgihoneyRO is a honey-based product that has been bioengineered to enable the slow release of H2 O2 , a reactive oxygen species to which H...
February 15, 2018: Journal of Clinical Pathology
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