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https://www.readbyqxmd.com/read/29352760/endothelial-function-estimated-by-digital-reactive-hyperemia-in-patients-with-atherosclerotic-risk-factors-or-coronary-artery-disease
#1
Jeehoon Kang, Hack-Lyoung Kim, Jae-Bin Seo, Jin-Yong Lee, Min-Kyong Moon, Woo-Young Chung
Due to the complex profile of atherosclerotic risk factors, an integrated analysis of a specific individual is difficult. Endothelial function reflects a composite of various risk factors, and may be used as an optimal tool to estimate the overall atherosclerotic risk. In this study, we investigated the value of digital Reactive Hyperemia Index (RHI) in an actual population with multiple atherosclerotic risk factors or coronary artery disease (CAD). A total of 417 patients from the Seoul National University Boramae Medical Center RHI registry were enrolled in this study...
January 19, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29352700/high-sensitivity-troponin-in-the-management-of-tachyarrhythmias
#2
Mark Mariathas, Cameron Gemmell, Bartosz Olechowski, Zoe Nicholas, Michael Mahmoudi, Nick Curzen
BACKGROUND: The introduction of the highly sensitive troponin (hs-trop) assays into clinical practice has allowed for the more rapid diagnosis or exclusion of type 1 myocardial infarctions (T1MI) by clinicians, in addition type 2 myocardial infarctions (T2MI) are now more frequently detected. Tachyarrhythmias are one of the common causes of T2MI, the medium and long term outcome for this cohort of T2MI is yet to be clarified. METHODS: Retrospective review of consecutive patients admitted with a diagnosis of either (a) non ST-elevation myocardial infarction (NSTEMI) or (b) tachyarrhythmia was performed...
November 28, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29352602/a-rare-cause-of-pyogenic-flexor-tenosynovitis-nocardia-nova
#3
Andrew Wilhelm, Nicholas Romeo, Richard Trevino
Infection complicates approximately 5% of open trigger digit releases. Both superficial and deep infections may occur. We present a unique case of a cactus farmer who underwent an uneventful thumb trigger finger release and subsequently developed pyogenic flexor tenosynovitis and acute carpal tunnel syndrome resulting from Nocardia nova infection.
January 15, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29352495/ultrasonographic-based-predictive-factors-influencing-successful-return-to-racing-after-superficial-digital-flexor-tendon-injuries-in-flat-racehorses-a-retrospective-cohort-study-in-469-thoroughbred-racehorses-in-hong-kong
#4
R Alzola, C Easter, C M Riggs, D S Gardner, S L Freeman
BACKGROUND: Superficial digital flexor tendon (SDFT) injury is an important health and welfare concern in racehorses. It is generally diagnosed with ultrasonography, predictive ultrasonographic features have not been reported. OBJECTIVES: To determine ultrasonographic features of forelimb SDFT injury at initial presentation in Thoroughbred racehorses, that could predict a successful return to racing (completing ≥5 races). STUDY DESIGN: Retrospective cohort study...
January 20, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29352460/pelvic-floor-muscle-function-and-quality-of-life-in-post-menopausal-women-with-and-without-pelvic-floor-dysfunction
#5
Isabella Parente Ribeiro Frota, Adriana Bombonato Oliveira Rocha, José Ananias Vasconcelos Neto, Camila Teixeira Moreira Vasconcelos, Thais Fontes De Magalhaes, Sara Arcanjo Lino Karbage, Kathiane Lustosa Augusto, Simony Lira Do Nascimento, Jorge Millem Haddad, Leonardo Robson Pinheiro Sobreira Bezerra
This study aims to compare pelvic floor muscle (PFM) function in post-menopause women with and without pelvic floor dysfunction (PFD) and the relationship between PFM function and quality of life MATERIAL AND METHODS: a case-control study with 216 post-menopause women with (n=126) and without PFD (n=90). PFM function was assessed by digital vaginal palpation using PERFECT scale. Specific quality of life was evaluated by King's Health Questionnaire for women with urinary incontinence and Prolapse Quality-of-Life Questionnaire for women with pelvic organ prolapse...
January 20, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29352400/project-date-smart-a-dating-violence-dv-and-sexual-risk-prevention-program-for-adolescent-girls-with-prior-dv-exposure
#6
Christie J Rizzo, Meredith Joppa, David Barker, Charlene Collibee, Caron Zlotnick, Larry K Brown
This study assessed the initial feasibility, acceptability, and efficacy of an intervention aimed at reducing dating violence and sexual risk behavior in a sample of adolescent girls (ages 14-17) with prior exposure to physical dating violence (DV). One hundred and nine girls were randomly assigned to Date SMART (Skills to Manage Aggression in Relationships for Teens) or a Knowledge-only (KO) comparison group. Both intervention arms consisted of six, weekly 2-h sessions and one "booster" session 6 weeks later...
January 20, 2018: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29352322/qportal-a-platform-for-data-driven-biomedical-research
#7
Christopher Mohr, Andreas Friedrich, David Wojnar, Erhan Kenar, Aydin Can Polatkan, Marius Cosmin Codrea, Stefan Czemmel, Oliver Kohlbacher, Sven Nahnsen
Modern biomedical research aims at drawing biological conclusions from large, highly complex biological datasets. It has become common practice to make extensive use of high-throughput technologies that produce big amounts of heterogeneous data. In addition to the ever-improving accuracy, methods are getting faster and cheaper, resulting in a steadily increasing need for scalable data management and easily accessible means of analysis. We present qPortal, a platform providing users with an intuitive way to manage and analyze quantitative biological data...
2018: PloS One
https://www.readbyqxmd.com/read/29352274/compliance-free-digital-set-and-analog-reset-synaptic-characteristics-of-sub-tantalum-oxide-based-neuromorphic-device
#8
Yawar Abbas, Yu-Rim Jeon, Andrey Sergeevich Sokolov, Sohyeon Kim, Boncheol Ku, Changhwan Choi
A two terminal semiconducting device like a memristor is indispensable to emulate the function of synapse in the working memory. The analog switching characteristics of memristor play a vital role in the emulation of biological synapses. The application of consecutive voltage sweeps or pulses (action potentials) changes the conductivity of the memristor which is considered as the fundamental cause of the synaptic plasticity. In this study, a neuromorphic device using an in-situ growth of sub-tantalum oxide switching layer is fabricated, which exhibits the digital SET and analog RESET switching with an electroforming process without any compliance current (compliance free)...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29352126/role-of-subcortical-structures-on-cognitive-and-social-function-in-schizophrenia
#9
Daisuke Koshiyama, Masaki Fukunaga, Naohiro Okada, Fumio Yamashita, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Kazutaka Ohi, Haruo Fujino, Yoshiyuki Watanabe, Kiyoto Kasai, Ryota Hashimoto
Subcortical regions have a pivotal role in cognitive, affective, and social functions in humans, and the structural and functional abnormalities of the regions have been associated with various psychiatric disorders. Although previous studies focused on the neurocognitive and socio-functional consequences of prefrontal and tempolo-limbic abnormalities in psychiatric disorders, those of subcortical structures remain largely unknown. Recently, MRI volume alterations in subcortical structures in patients with schizophrenia have been replicated in large-scale meta-analytic studies...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29352043/prognostic-implications-of-multiplex-detection-of-kras-mutations-in-cell-free-dna-from-patients-with-pancreatic-ductal-adenocarcinoma
#10
Min Kyeong Kim, Sang Myung Woo, Boram Park, Kyong-Ah Yoon, Yun-Hee Kim, Jungnam Joo, Woo Jin Lee, Sung-Sik Han, Sang-Jae Park, Sun-Young Kong
BACKGROUND: Cell-free DNA (cfDNA) is known to provide potential biomarkers for predicting clinical outcome, but its value in pancreatic ductal adenocarcinoma (PDAC) has not been fully evaluated. The aim of this study was to evaluate the clinical applicability of quantitative analysis of multiplex KRAS mutations in cell-free DNA from patients with PDAC. METHODS: A total of 106 patients with PDAC were enrolled in this prospective study. The concentration and fraction of KRAS mutations were determined through multiplex detection of KRAS mutations in plasma samples by use of a droplet digital PCR kit (Bio-Rad)...
January 19, 2018: Clinical Chemistry
https://www.readbyqxmd.com/read/29351931/stent-assisted-coil-embolization-on-down-the-barrel-view-with-spring-shaped-microcatheter-in-patient-with-m1-ultrawide-necked-circumferential-aneurysm
#11
Hyo Sung Kwak, Jung Soo Park, Eun Jeong Koh
Herein, we describe a technique for stent-assisted coil embolization with a spring-shaped microcatheter in a patient with an M1 ultrawide-necked circumferential aneurysm in the middle cerebral artery (MCA). A 49-year-old man was referred for treatment of an incidentally detected M1 large-circumference aneurysm on magnetic resonance angiography. Subsequent digital subtraction angiography revealed an 18.2×16.5 mm ultrawide-necked circumferential aneurysm on the distal M1 portion of the left MCA, and we planned stent-assisted coil embolization using a spring-shaped microcatheter...
January 18, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29351900/employees-perspectives-on-the-facilitators-and-barriers-to-engaging-with-digital-mental-health-interventions-in-the-workplace-qualitative-study
#12
Stephany Carolan, Richard O de Visser
BACKGROUND: Prevalence rates of work-related stress, depression, and anxiety are high, resulting in reduced productivity and increased absenteeism. There is evidence that these conditions can be successfully treated in the workplace, but take-up of psychological treatments among workers is low. Digital mental health interventions delivered in the workplace may be one way to address this imbalance, but although there is evidence that digital mental health is effective at treating stress, depression, and anxiety in the workplace, uptake of and engagement with these interventions remains a concern...
January 19, 2018: JMIR Mental Health
https://www.readbyqxmd.com/read/29351896/internet-exposure-associated-with-canadian-parents-perception-of-risk-on-childhood-immunization-cross-sectional-study
#13
Jordan Lee Tustin, Natasha Sarah Crowcroft, Dionne Gesink, Ian Johnson, Jennifer Keelan
BACKGROUND: There is a large presence of provaccination and antivaccination content on the Internet. The Internet has been identified as an important source for parents to seek and share vaccine information. There are concerns that parental fears or hesitancy on childhood immunizations are increasing due to the popularity of social media and exposure to online antivaccination sentiment. No other studies have investigated the association between seeking vaccine information online and Canadian parents' perception of risk on childhood immunization...
January 19, 2018: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29351863/size-congruity-influences-visual-search-via-the-target-template
#14
Kenith V Sobel, Amrita M Puri
In numerical comparison experiments, participants are presented with two digits that vary in numerical and physical size, and they select the numerically (or physically) larger (or smaller) of the two digits. Response times are typically faster when numerical and physical size are congruent than when they are incongruent, which is called the size congruity effect (SCE). Although numerical size is unlikely to be a guiding feature in visual search, recent studies have nevertheless observed the SCE in the visual search paradigm...
January 16, 2018: Acta Psychologica
https://www.readbyqxmd.com/read/29351821/reliability-of-the-american-academy-of-sleep-medicine-rules-for-assessing-sleep-depth-in-clinical-practice
#15
Magdy Younes, Samuel T Kuna, Allan I Pack, James K Walsh, Clete A Kushida, Bethany Staley, Grace W Pien
STUDY OBJECTIVES: The American Academy of Sleep Medicine has published manuals for scoring polysomnograms that recommend time spent in non-rapid eye movement sleep stages (stage N1, N2, and N3 sleep) be reported. Given the well-established large interrater variability in scoring stage N1 and N3 sleep, we determined the range of time in stage N1 and N3 sleep scored by a large number of technologists when compared to reasonably estimated true values. METHODS: Polysomnograms of 70 females were scored by 10 highly trained sleep technologists, two each from five different academic sleep laboratories...
January 16, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29351351/comparing-performance-on-the-mnread-ipad-application-with-the-mnread-acuity-chart
#16
Aurélie Calabrèse, Long To, Yingchen He, Elizabeth Berkholtz, Paymon Rafian, Gordon E Legge
Our purpose was to compare reading performance measured with the MNREAD Acuity Chart and an iPad application (app) version of the same test for both normally sighted and low-vision participants. Our methods included 165 participants with normal vision and 43 participants with low vision tested on the standard printed MNREAD and on the iPad app version of the test. Maximum Reading Speed, Critical Print Size, Reading Acuity, and Reading Accessibility Index were compared using linear mixed-effects models to identify any potential differences in test performance between the printed chart and the iPad app...
January 1, 2018: Journal of Vision
https://www.readbyqxmd.com/read/29351349/survey-research-with-a-random-digit-dial-national-mobile-phone-sample-in-ghana-methods-and-sample-quality
#17
Kelly L'Engle, Eunice Sefa, Edward Akolgo Adimazoya, Emmanuel Yartey, Rachel Lenzi, Cindy Tarpo, Nii Lante Heward-Mills, Katherine Lew, Yvonne Ampeh
INTRODUCTION: Generating a nationally representative sample in low and middle income countries typically requires resource-intensive household level sampling with door-to-door data collection. High mobile phone penetration rates in developing countries provide new opportunities for alternative sampling and data collection methods, but there is limited information about response rates and sample biases in coverage and nonresponse using these methods. We utilized data from an interactive voice response, random-digit dial, national mobile phone survey in Ghana to calculate standardized response rates and assess representativeness of the obtained sample...
2018: PloS One
https://www.readbyqxmd.com/read/29351325/impact-of-educational-interventions-on-adolescent-attitudes-and-knowledge-regarding-vaccination-a-pilot-study
#18
Kate Carolan, Joanna Verran, Matthew Crossley, James Redfern, Nicola Whitton, Martyn Amos
BACKGROUND: Current immunisation levels in England currently fall slightly below the threshold recommended by the World Health Organization, and the three-year trend for vaccination uptake is downwards. Attitudes towards vaccination can affect future decisions on whether or not to vaccinate, and this can have significant public health implications. Interventions can impact future vaccination decisions, and these interventions can take several forms. Relatively little work has been reported on the use of vaccination interventions in young people, who form the next generation of individuals likely to make vaccination decisions...
2018: PloS One
https://www.readbyqxmd.com/read/29351293/fibroblast-growth-factor-receptor-1-amplification-in-laryngeal-squamous-cell-carcinoma
#19
Jesus Monico, Brandon Miller, Luminita Rezeanu, Warren May, Donna C Sullivan
Fibroblast growth factor receptor 1 (FGFR1) has been noted to be amplified in a variety of squamous cell carcinomas (SCCa) of the head, neck, and lung and increased copy number (CN) is a predictor of poor outcomes. FGFR1 is a therapeutic target for lung SCCa and inhibition therapy is currently in clinical trials. Absolute quantification of FGFR1 from formalin fixed paraffin embedded (FFPE) tissue of laryngeal SCCa was examined in this retrospective study. A droplet digital polymerase chain reaction (ddPCR) was used for absolute quantitation of the FGFR1 gene CN...
2018: PloS One
https://www.readbyqxmd.com/read/29351218/transparent-fingerprint-sensor-system-for-large-flat-panel-display
#20
Wonkuk Seo, Jae-Eun Pi, Sung Haeung Cho, Seung-Youl Kang, Seong-Deok Ahn, Chi-Sun Hwang, Ho-Sik Jeon, Jong-Uk Kim, Myunghee Lee
In this paper, we introduce a transparent fingerprint sensing system using a thin film transistor (TFT) sensor panel, based on a self-capacitive sensing scheme. An armorphousindium gallium zinc oxide (a-IGZO) TFT sensor array and associated custom Read-Out IC (ROIC) are implemented for the system. The sensor panel has a 200 × 200 pixel array and each pixel size is as small as 50 μm × 50 μm. The ROIC uses only eight analog front-end (AFE) amplifier stages along with a successive approximation analog-to-digital converter (SAR ADC)...
January 19, 2018: Sensors
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