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https://www.readbyqxmd.com/read/29239804/sex-determination-and-differentiation-genes-in-a-functional-hermaphrodite-scallop-nodipecten-subnodosus
#1
Pavel Galindo-Torres, Alejandra García-Gasca, Raúl Llera-Herrera, Cristina Escobedo-Fregoso, Cei Abreu-Goodger, Ana M Ibarra
The lion-paw, Nodipecten subnodosus is one of three scallop species commercially exploited on the west coast of the Peninsula of Baja California. Because nothing is known about sex determination and sexual differentiation in hermaphrodite scallops, in the present work, a global transcriptomic analysis was performed in two early developmental stages, settling eyed-larvae and spat, as well as in three tissues (undifferentiated gonad, digestive gland, and adductor muscle). Over 27 million Illumina paired-end reads were obtained through the MiSeq platform...
November 24, 2017: Marine Genomics
https://www.readbyqxmd.com/read/29234483/the-influence-of-emerging-markets-on-the-pharmaceutical-industry
#2
REVIEW
Maya Tannoury, Zouhair Attieh
Emerging markets represent an exceptional opportunity for the pharmaceutical industry. Although a precise definition is not yet available, economists define emerging markets as developing prosperous countries in which investment is expected to result in higher income despite high risks. Qualifying a market as emerging is not merely based on the economic status of the country, but also on several criteria that render the definition applicable to each country. Jim O'Neil, retired chairman of asset management at Goldman Sachs, identified leading economies of emerging markets: Brazil, Russia, India, and China (BRIC) and later Brazil, Russia, India, China, and South Africa (BRICS) and then Mexico, Indonesia, South Korea, and Turkey (MIST), which followed years later as the second tier of nations...
2017: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/29231058/efaverinz-and-nano-gold-loaded-mannosylated-niosomes-a-host-cell-targeted-topical-hiv-1-prophylaxis-via-thermogel-system
#3
Tanushree Malik, Gaurav Chauhan, Goutam Rath, Rohan N Kesarkar, Abhay S Chowdhary, Amit K Goyal
Sexual dissemination of Human Immunodeficiency Virus-1 (HIV-1) is the prime mode of its spread. Topical microbicidal approach has gained much attention, but no real success is observed till date, either due to toxicity or resistance of active moieties and the lack of efficient drug delivery approaches. In this research protocol, a unique combination approach of a standard drug moiety, that is, Efaverinz (EFV) and a nanometal, that is, gold nanoparticles (GNPs) was tried. Both these candidates were delivered through a mannosylated niosomal system, to exploit protein (lectins present on HIV host cells) - carbohydrate (oligosaccharides such as mannan present on HIV gp-120 receptor) interaction...
December 12, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29195171/commercially-sexually-exploited-youths-health-care-experiences-barriers-and-recommendations-a-qualitative-analysis
#4
Roya Ijadi-Maghsoodi, Eraka Bath, Mekeila Cook, Lauren Textor, Elizabeth Barnert
The current study sought to understand commercially sexually exploited (CSE) youths' health care experiences, barriers to care, and recommendations for improving health care services. We conducted focus groups (N=5) with 18 CSE youth from February 2015 through May 2016 at two group homes serving CSE youth in Southern California. We performed thematic content analysis to identify emergent themes about CSE youths' perspectives on health care. Youth described facilitators to care, including availability of services such as screening for sexually transmitted infections, knowledge about sexual health, and a strong motivation to stay healthy...
November 28, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29186618/semi-automatized-segmentation-method-using-image-based-flow-cytometry-to-study-sperm-physiology-the-case-of-capacitation-induced-tyrosine-phosphorylation
#5
Arturo Matamoros-Volante, Ayelen Moreno-Irusta, Paulina Torres-Rodriguez, Laura Giojalas, María G Gervasi, Pablo E Visconti, Claudia L Treviño
STUDY QUESTION: Is image-based flow cytometry a useful tool to study intracellular events in human sperm such as protein tyrosine phosphorylation or signaling processes? SUMMARY ANSWER: Image-based flow cytometry is a powerful tool to study intracellular events in a relevant number of sperm cells, which enables a robust statistical analysis providing spatial resolution in terms of the specific subcellular localization of the labeling. WHAT IS KNOWN ALREADY: Sperm capacitation is required for fertilization...
November 25, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29180462/global-human-trafficking-and-child-victimization
#6
Jordan Greenbaum, Nia Bodrick
Trafficking of children for labor and sexual exploitation violates basic human rights and constitutes a major global public health problem. Pediatricians and other health care professionals may encounter victims who present with infections, injuries, posttraumatic stress disorder, suicidality, or a variety of other physical or behavioral health conditions. Preventing child trafficking, recognizing victimization, and intervening appropriately require a public health approach that incorporates rigorous research on the risk factors, health impact, and effective treatment options for child exploitation as well as implementation and evaluation of primary prevention programs...
November 27, 2017: Pediatrics
https://www.readbyqxmd.com/read/29166401/sexual-exploitation-of-unaccompanied-migrant-and-refugee-boys-in-greece-approaches-to-prevention
#7
Julie Freccero, Dan Biswas, Audrey Whiting, Khaled Alrabe, Kim Thuy Seelinger
In this essay, Julie Freccero and colleagues discuss resources to prevent the sexual exploitation of unaccompanied and separated refugee boys in Greece.
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29166394/maternity-care-for-trafficked-women-survivor-experiences-and-clinicians-perspectives-in-the-united-kingdom-s-national-health-service
#8
Debra Bick, Louise M Howard, Sian Oram, Cathy Zimmerman
BACKGROUND: Although trafficked women and adolescents are at risk of unprotected or forced sex, there is little research on maternity care among trafficking survivors. We explored health care needs, service use and challenges among women who became pregnant while in the trafficking situation in the United Kingdom (UK) and clinicians' perspectives of maternity care for trafficked persons. METHODS: Cross-sectional survey and qualitative interviews with trafficking survivors recruited from statutory and voluntary sector organisations in England and qualitative interviews with maternity clinicians and family doctors undertaken to offer further insight into experiences reported by these women...
2017: PloS One
https://www.readbyqxmd.com/read/29164180/you-can-t-burn-the-house-down-because-of-one-bedbug-a-qualitative-study-of-changing-gender-norms-in-the-prevention-of-violence-against-women-and-girls-in-an-urban-informal-settlement-in-india
#9
Nayreen Daruwalla, Ketaki Hate, Preethi Pinto, Gauri Ambavkar, Bhaskar Kakad, David Osrin
Background: The contribution of structural inequalities and societal legitimisation to violence against women, which 30% of women in India survive each year, is widely accepted. There is a consensus that interventions should aim to change gender norms, particularly through community mobilisation. How this should be done is less clear. Methods: We did a qualitative study in a large informal settlement in Mumbai, an environment that characterises 41% of households. After reviewing the anonymised records of consultations with 1653 survivors of violence, we conducted 5 focus group discussions and 13 individual interviews with 71 women and men representing a range of age groups and communities...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/29161219/a-case-study-perspective-the-experiences-of-young-persons-testifying-to-child-sexual-exploitation-in-british-criminal-court
#10
Elizabeth Ahern, Marlene Kowalski, Michael E Lamb
Three young persons who gave evidence about child sexual exploitation in criminal court using various testimonial supports were interviewed about their testimony experiences. The witnesses reported that they felt extreme pressure to remember events accurately and cared greatly about being believed. None reported their own coping strategies to alleviate stress and took comfort breaks only after they cried on the stand. Defense attorney questions were reportedly repetitive, rapid, confusing, and focused on secondary content rather than the central criminal acts...
November 21, 2017: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/29157504/domestic-minor-sex-trafficking
#11
REVIEW
Amy Goldberg, Jessica Moore
Commercial sexual exploitation of children and child sex trafficking is a major public health issue globally. Domestic minor sex trafficking has become increasingly recognized within the United States. Sexually exploited minors are commonly identified as having psychosocial risk factors, including histories of abuse or neglect, running away, substance use or abuse, and involvement with child protective services. Youth also suffer a variety of physical and mental health consequences, including posttraumatic stress disorder, depression, anxiety, and suicidality...
January 2018: Child and Adolescent Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/29149683/online-sexual-solicitation-by-adults-and-peers-results-from-a-population-based-german-sample
#12
Halina Sklenarova, Anja Schulz, Petya Schuhmann, Michael Osterheider, Janina Neutze
Prevalence of Internet use among adolescents is high, but little is known about the online sexual activities of German adolescents. This study aimed to describe the 12-month prevalence of German adolescents' online sexual experiences with a focus on Online Sexual Solicitation (OSS, subjectively negative online sexual experiences with a peer or any sexual online experience, positive or negative, with an adult). A sample of male and female adolescents aged 14-17 (N=2238) was recruited using online survey panel...
November 14, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29146584/microrna-tissue-atlas-of-the-malaria-mosquito-anopheles-gambiae
#13
Lena Lampe, Elena A Levashina
Anopheles gambiae mosquitoes transmit the human malaria parasite Plasmodium falciparum, which causes the majority of fatal malaria cases worldwide. The hematophagous life style defines the mosquito reproductive biology and is exploited by P. falciparum for its own sexual reproduction and transmission. The two main phases of the mosquito reproductive cycle, pre-vitellogenic (PV) and post-blood meal (PBM) shape its capacity to transmit malaria. Transition between these phases is tightly coordinated to ensure homeostasis between mosquito tissues and successful reproduction...
November 16, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29121905/the-trafficking-of-women-and-girls-in-taiwan-characteristics-of-victims-perpetrators-and-forms-of-exploitation
#14
Lanying Huang
BACKGROUND: Prior to the passing of 2009 Human Trafficking Prevention Act (HTPA), human trafficking was underestimated in Taiwan. In the past, domestic trafficking in women and girls often targeted vulnerable groups such as young girls from poor families or minority groups. Since the 1990s, an increasing flow of immigrant women, mainly from Vietnam and Indonesia and some from China, into Taiwan has created a new group of Human Trafficking victims. The current study intends to identify, describe, and categorize reported and prosecuted human trafficking cases involving women and girls according to the HTPA in Taiwan...
November 9, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29121553/stewards-of-children-education-increasing-undergraduate-nursing-student-knowledge-of-child-sexual-abuse
#15
L Elaine Taylor, Heather S Harris
BACKGROUND: Child sexual abuse and exploitation are an increasing public health problem. In spite of the fact that nurses are in a unique position to identify and intervene in the lives of children suffering from abuse due to their role in providing health care in a variety of settings, nursing curricula does not routinely include this focus. OBJECTIVES: The goal was to document the effectiveness of the Stewards of Children child sexual abuse training as an effective educational intervention to increase the knowledge level of undergraduate nursing students on how to prevent, recognize, and react responsibly to child sexual abuse and trafficking...
October 24, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29120276/personality-disorder-features-and-paraphilic-interests-among-undergraduates-differential-relations-and-potential-antecedents
#16
Ashley L Watts, Madeline G Nagel, Robert D Latzman, Scott O Lilienfeld
We examined the relations between: (1) narcissism, psychopathy, DSM-5 personality disorder symptom counts; and (2) paraphilic interests among undergraduates (N = 608). Base rates of paraphilic interests were appreciable. The disinhibition and meanness features of psychopathy and the entitlement and exploitativeness features of narcissism were robustly associated with paraphilic interests, particularly sexual sadism, whereas the boldness features of narcissism and psychopathy were essentially unrelated to these interests...
November 9, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29114350/indira-s-story
#17
Russell Dawe
Indira is an independent woman who does not live a traditional Nepali life. She rescues abandoned and abused young women from sexual exploitation and provides them with love, support, and education. Her story highlights the key role of the social determinants of health in caring for marginalized populations. Challenges and benefits of attempting to learn from another's personal narrative are also considered.
April 2017: Canadian Medical Education Journal
https://www.readbyqxmd.com/read/29103001/contraception-for-adolescents-with-disabilities-taking-control-of-periods-cycles-and-conditions
#18
REVIEW
Jane Dickson, Annette Thwaites, Lesley Bacon
The onset of puberty, periods and sexual relationships can be difficult for adolescents and parents. Adolescents with disabilities face a wide range of additional challenges (physical, mental, social and intellectual), which may impact the quality of their lives and those of their families and carers. Research on the use of contraception in young women with disabilities is limited, and clinicians have little practical guidance for best practice. This review article aims to summarise and assess the evidence and guidance for the use of contraception in this group, particularly with regard to management of menstrual and cyclical problems...
November 4, 2017: Journal of Family Planning and Reproductive Health Care
https://www.readbyqxmd.com/read/29095040/prevalence-and-risk-factors-among-minors-for-online-sexual-solicitations-and-interactions-with-adults
#19
Patricia de Santisteban, Manuel Gámez-Guadix
The research on online child sexual victimization has mainly focused on the sexual solicitation of minors (i.e., sexual requests by an adult), with scarce information available on sexual interactions (e.g., cybersex or meeting in person) in which a minor is exploited by an adult. In the present study, we analyzed the prevalence and risk factors associated with both sexual solicitations and interactions of minors with adults. The sample included 2,731 minors between 12 and 15 years old (50.6% female). The minors completed several self-report questionnaires about sexual solicitations and interactions with adults, including possible risk factors (e...
November 2, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29073793/infertility-and-surrogacy-first-mentioned-on-a-4000-year-old-assyrian-clay-tablet-of-marriage-contract-in-turkey
#20
Ahmet Berkiz Turp, Ismail Guler, Nuray Bozkurt, Aysel Uysal, Bulent Yilmaz, Mustafa Demir, Onur Karabacak
Mankind has been expressing the breeding topic for thousands of years. Reproduction is the primary instinct of human beings and it is a social, cultural, medical issue. Demographic infertility is one of them, which is defined infertility as the inability to become pregnant with a live birth, within five years of regular sexual contact based upon a consistent union status in marriage maintaining a desire for a child with the lack of contraceptive use and non-lactating. A first mentions about infertility and surrogacy is discovered on a 4000-year-old clay tablet of marriage contract belonging to the Assyrian period exhibited at Istanbul Archeology Museum in Turkey...
October 26, 2017: Gynecological Endocrinology
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