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Gynecologic cancer, minimally invasive surgery

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https://www.readbyqxmd.com/read/28515257/minimally-invasive-techniques-for-treating-gynecologic-malignancies
#1
Amanda N Fader
For many women with endometrial and cervical cancers, minimally invasive surgery represents an alternative standard of care to open abdominal procedures, with fewer complications, better postoperative quality of life, and overall lower cost. At the NCCN 22nd Annual Conference, Amanda N. Fader, MD, reviewed several minimally invasive strategies for treating gynecologic cancers, including conventional laparoscopy, robotic-assisted laparoscopy, sentinel lymph node technology, and single-port surgery; highlighted some of the contemporary literature on the role of these procedures; and explored some of the challenges and barriers to their successful performance...
May 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28479170/assessing-the-risk-of-occult-cancer-and-30-day-morbidity-in-women-undergoing-risk-reducing-surgery-a-prospective-experience
#2
Giorgio Bogani, Elena Tagliabue, Mauro Signorelli, Valentina Chiappa, Maria Luisa Carcangiu, Biagio Paolini, Jvan Casarin, Cono Scaffa, Massimiliano Gennaro, Fabio Martinelli, Chiara Borghi, Antonino Ditto, Domenica Lorusso, Francesco Raspagliesi
STUDY OBJECTIVE: To investigate the incidence and predictive factors of 30-day surgery-related morbidity and occult precancerous and cancerous conditions for women undergoing risk-reducing surgery. DESIGN: Prospective study (Canadian Task Force classification II-1). SETTING: Gynecologic oncology referral center. PATIENTS: Breast Related Cancer Antigen (BRCA) mutation carriers and BRCAx patients (those with significant family history of breast and ovarian cancer)...
May 4, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28382802/major-clinical-research-advances-in-gynecologic-cancer-in-2016-10-year-special-edition
#3
REVIEW
Dong Hoon Suh, Miseon Kim, Kidong Kim, Hak Jae Kim, Kyung Hun Lee, Jae Weon Kim
In 2016, 13 topics were selected as major research advances in gynecologic oncology. For ovarian cancer, study results supporting previous ones regarding surgical preventive strategies were reported. There were several targeted agents that showed comparable responses in phase III trials, including niraparib, cediranib, and nintedanib. On the contrary to our expectations, dose-dense weekly chemotherapy regimen failed to prove superior survival outcomes compared with conventional triweekly regimen. Single-agent non-platinum treatment to prolong platinum-free-interval in patients with recurrent, partially platinum-sensitive ovarian cancer did not improve and even worsened overall survival (OS)...
May 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28353387/recent-developments-in-surgical-pathology-of-the-uterine-corpus
#4
REVIEW
Krisztina Z Hanley, George G Birdsong, Marina B Mosunjac
There have been several updates recently on the classification of uterine tumors. Endometrial carcinomas have traditionally been divided into 2 types, but some are difficult to classify and do not fit readily into either of the currently recognized categories. The Cancer Genome Atlas Research Network has recently defined 4 new categories of endometrial cancer on the basis of mutational spectra, copy number alteration, and microsatellite instability, which might provide independent prognostic information beyond established risk factors...
April 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28336363/does-surgical-teaching-take-time-resident-participation-in-minimally-invasive-hysterectomy-for-endometrial-cancer
#5
Alexandra H Freeman, Allison Barrie, Liisa Lyon, Carol Conell, Christine Garcia, Ramey D Littell, C Bethan Powell
STUDY OBJECTIVE: To determine the association between resident involvement and operative time for minimally invasive surgery (MIS) for endometrial cancer. DESIGN: Retrospective cohort study DESIGN: Classification: II-2 SETTING: Integrated health care system in Northern California PATIENTS: A total of 1,433 women who underwent MIS for endometrial cancer and endometrial intraepithelial neoplasia from January 2009 to January 2014. INTERVENTIONS: Resident participation in 430/688 laparoscopic cases (62%) and 341/745 robotic cases (46%)...
March 21, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28187093/minimally-invasive-surgery-to-treat-gynecological-cancer-conventional-laparoscopy-and-or-robot-assisted-surgery
#6
Lucas Minig, María Teresa Achilarre, Annalisa Garbi, Vanna Zanagnolo
Robotic-assisted surgery is a technological advancement derived from conventional laparoscopy, which facilitates the application of minimally invasive techniques for complex operations in the field of gynecological oncology. However, its introduction in gynecological cancer has been scarce in most hospitals worldwide. Most publications on robotic surgery are still retrospective or descriptive in nature. Some studies compare robotic-assisted laparoscopy with open procedures, which is a questionable analysis, because the advantages of minimally invasive surgery have been already well established...
March 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28187092/incidence-of-venous-thromboembolism-by-type-of-gynecologic-malignancy-and-surgical-modality-in-the-national-surgical-quality-improvement-program
#7
Ashley Graul, Nawar Latif, Xiaochen Zhang, Lorraine T Dean, Mark Morgan, Robert Giuntoli, Robert Burger, Sarah Kim, Emily Ko
BACKGROUND: Women with gynecologic cancer are at higher risk of venous thromboembolism (VTE) due to malignancy, pelvic surgery, increased age, and frequently comorbidities. The rate of VTE among different gynecologic cancers and relative to benign gynecologic surgeries has not been reported in a nationally representative cohort. METHODS: Using the American College of Surgeons National Surgical Quality Improvement Program database, gynecologic surgeries were identified retrospectively from 2006 to 2012...
March 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28179200/laparoscopic-management-of-abdomininal-pregnancy
#8
Francesco Cosentino, Cristiano Rossitto, Luigi Carlo Turco, Salvatore Gueli Alletti, Carmine Vascone, Lavinia Di Meglio, Giovanni Scambia, Mario Malzoni
CASE REPORT OBJECTIVE: To show the surgical management in laparoscopy of a particular localization of an extra-uterine pregnancy misunderstood until 12 week of EG complicated by hemoperitoneum and abortion. BACKGROUND: The prevalence of ectopic pregnancy among women who go to an emergency department with first trimester bleeding, pain, or both ranges from 1 to 16 percent [1]. The most common localization of ectopic pregnancy are the Fallopian tubes while abdominal pregnancy represent at least 1 percent of extra-uterine pregnancies...
February 4, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28147240/the-effect-of-a-uterine-manipulator-on-the-recurrence-and-mortality-of-endometrial-cancer-a-multi-centric-study-by-the-italian-society-of-gynecological-endoscopy
#9
Stefano Uccella, Matteo Bonzini, Mario Malzoni, Francesco Fanfani, Stefano Palomba, Giovanni Aletti, Giacomo Corrado, Marcello Ceccaroni, Renato Seracchioli, Fevzi Shakir, Annamaria Ferrero, Roberto Berretta, Raffaele Tinelli, Enrico Vizza, Giovanni Roviglione, Lucia Casarella, Eugenio Volpi, Ettore Cicinelli, Giovanni Scambia, Fabio Ghezzi
BACKGROUND: Although widely adopted, the use of a uterine manipulator during laparoscopic treatment of endometrial cancer represents a debated issue, and some authors hypothesize that it potentially may cause an increased risk of relapse, particularly at specific sites. OBJECTIVE: Our aim was to evaluate the risk and site of disease recurrence, overall survival, and disease-specific survival in women who had laparoscopic surgery with and without the use of a uterine manipulator...
January 29, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28104497/robot-assisted-surgery-in-gynecologic-cancers
#10
REVIEW
Vanna Zanagnolo, Annalisa Garbi, Maria Teresa Achilarre, Lucas Minig
Robotic-assisted surgery is a technological advancement that facilitates the application of minimally invasive techniques for complex operations in gynecologic oncology. The objective of this article was to review the literature regarding the role of robotic-assisted surgery to treat women with gynecologic cancers. The majority of publications on robotic surgery are still retrospective or descriptive in nature; however, the data for managing patients with a robotic-assisted approach show comparable, and at times improved, outcomes compared with both laparoscopy (2-dimensional) and laparotomy approaches...
March 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28062330/minimally-invasive-cancer-surgery-indications-and-outcomes
#11
REVIEW
Virginia Sun, Yuman Fong
OBJECTIVES: To review the current evidence on the impact of minimally invasive, robotic-assisted cancer surgery (thoracic, gastrointestinal, gynecologic, genitourinary) on surgical outcomes and quality of life. DATA SOURCES: Journal articles, research reports, state of the science papers, and clinical guidelines. CONCLUSION: Minimally invasive cancer surgery is an important and integral component of the comprehensive care of cancer patients...
February 2017: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/27789387/evaluation-of-the-american-college-of-surgeons-national-surgical-quality-improvement-program-surgical-risk-calculator-in-gynecologic-oncology-patients-undergoing-minimally-invasive-surgery
#12
Deanna Teoh, Rebi Nahum Halloway, Jennifer Heim, Rachel Isaksson Vogel, Colleen Rivard
STUDY OBJECTIVE: To evaluate the ability of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) surgical risk calculator to predict discharge to postacute care and perioperative complications in gynecologic oncology patients undergoing minimally invasive surgery (MIS). DESIGN: A retrospective chart review (Canadian Task Force classification II-1). SETTING: A university hospital. PATIENTS: All patients undergoing MIS on the gynecologic oncology service from January 1, 2009, to December 30, 2013...
January 1, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27590380/long-term-survival-outcomes-of-laparoscopic-staging-surgery-in-treating-endometrial-cancer-20-years-of-follow-up
#13
Chyi-Long Lee, Soshi Kusunoki, Kuan-Gen Huang, Kai-Yun Wu, Chen-Yin Huang, Chih-Feng Yen
OBJECTIVE: To assess the long-term outcomes of laparoscopic staging surgery (LSS) in treating patients with endometrial carcinoma. MATERIALS AND METHODS: Patients with endometrial cancer who underwent LSS between June 1995 and June 2014 were prospectively registered. Perioperative data, complications, disease recurrence, and long-term survival were measured. RESULTS: The study included 287 consecutive patients [mean age (± standard deviation), 53±10...
August 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27528387/oncologic-and-obstetric-outcomes-of-early-stage-cervical-cancer-with-abdominal-radical-trachelectomy-single-institution-experience
#14
Satoshi Tamauchi, Hiroaki Kajiyama, Jun Sakata, Ryuichiro Sekiya, Shiro Suzuki, Mika Mizuno, Fumi Utsumi, Kaoru Niimi, Tomomi Kotani, Kiyosumi Shibata, Fumitaka Kikkawa
AIM: Radical trachelectomy (RT) is a widely used fertility-sparing treatment for patients with early cervical cancer (CCA). RT, however, is an investigational treatment, and its gynecological and obstetric efficacy are being investigated. We retrospectively assessed the efficacy of abdominal RT (ART) as a fertility-sparing surgery. METHODS: From 2010 to 2014, patients with stage IA2-IB1 CCA (tumor ≤2 cm) who wished to preserve their fertility underwent ART. The major outcomes were mortality, recurrence, pregnancy complications, and obstetric outcome...
December 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27477495/the-role-of-minimally-invasive-interval-debulking-surgery-in-advanced-epithelial-ovarian-cancer
#15
Gulden Menderes, Jonathan D Black, Masoud Azodi
No abstract text is available yet for this article.
September 2016: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/27403808/robotic-surgery-for-upper-gastrointestinal-cancer-current-status-and-future-perspectives
#16
REVIEW
Koichi Suda, Masaya Nakauchi, Kazuki Inaba, Yoshinori Ishida, Ichiro Uyama
Robotic surgery with the da Vinci Surgical System has been increasingly applied in a wide range of surgical specialties, especially in urology and gynecology. However, in the field of upper gastrointestinal (GI) tract, the da Vinci Surgical System has yet to be standard as a result of a lack of clear benefits in comparison with conventional minimally invasive surgery. We have been carrying out robotic gastrectomy and esophagectomy for operable patients with resectable upper GI malignancies since 2009, and have demonstrated the potential advantages of the use of the robot in possibly reducing postoperative local complications including pancreatic fistula following gastrectomy and recurrent laryngeal nerve palsy after esophagectomy, even though there have been a couple of problems to be solved including longer duration of operation and higher cost...
November 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27334223/complications-of-robotic-gynecologic-surgery-in-the-severely-morbidly-obese
#17
Jonathan A Cosin, Michelle A Brett Sutherland, Candace T Westgate, Hongbin Fang
BACKGROUND: Surgeons are increasingly faced with the challenge of caring for obese patients. Advanced laparoscopic procedures have been shown to be safe in women with high BMI, but conversion rates remain high. Because robotics holds many potential advantages over traditional laparoscopic surgery, we sought to evaluate the outcome of robotic-assisted gynecologic surgery in obese patients. METHODS: A retrospective chart review of obese female patients undergoing robotic gynecologic surgery between January 2008 and August 2010 was done...
June 22, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27175680/effect-of-dexmedetomidine-alone-for-intravenous-patient-controlled-analgesia-after-gynecological-laparoscopic-surgery-a-consort-prospective-randomized-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Xiuqin Wang, Wenjuan Liu, Zan Xu, Fumei Wang, Chuanfeng Zhang, Baosheng Wang, Kaiguo Wang, Jingui Yu
Gynecological laparoscopic surgery is minimally invasive compared with open surgical approaches, but postoperative pain is generally undermanaged. Pain management strategies related to the procedure-specific efficacy are needed. Many studies have shown that dexmedetomidine (DEX) has opioid-sparing properties. It is not clear whether DEX used alone for intravenous patient-controlled analgesia (PCA) could reduce postoperative pain after an invasive procedure. We hypothesized that DEX alone would reduce postoperative pain in women patients undergoing an elective gynecological laparoscopic procedure...
May 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27131589/the-impact-of-surgical-complications-on-health-related-quality-of-life-in%C3%A2-women-undergoing-gynecologic-and-gynecologic-oncology-procedures-a-prospective-longitudinal-cohort-study
#19
Kemi M Doll, Emma L Barber, Jeannette T Bensen, Matthew C Revilla, Anna C Snavely, Antonia V Bennett, Bryce B Reeve, Paola A Gehrig
BACKGROUND: There are currently no assessments of the impact of surgical complications on health-related quality of life in gynecology and gynecologic oncology. This is despite complications being a central focus of surgical outcome measurement, and an increasing awareness of the need for patient-reported data when measuring surgical quality. OBJECTIVE: We sought to measure the impact of surgical complications on health-related quality of life at 1 month postoperatively, in women undergoing gynecologic and gynecologic oncology procedures...
October 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27066936/complications-in-gynecological-minimal-access-oncosurgery
#20
REVIEW
Sven Becker, Rudy Leon De Wilde
Complications are the limiting factors of all surgeries. More than performing the actual surgery, learning how to avoid complications before, during, and after surgery is the most important task of every surgeon. Severe complications can lead to patient death. Complications such as ureterovaginal fistulas, resulting from <2 s of inattentive preparation, can lead to years of hardship, suffering, accusation, and litigation. Excellent surgery is about performing the right surgery for the right patient without any complications...
August 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
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