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https://www.readbyqxmd.com/read/29758121/the-perspectives-of-former-recipients-and-experts-on-stigmatization-related-to-electroconvulsive-therapy-in-denmark-a-focus-group-study
#1
Iben Sylvia Kring, Maria Daniella Bergholt, Julie Midtgaard
INTRODUCTION: Electroconvulsive therapy (ECT) has existed worldwide for nearly 80 years. Although fast working and potentially life-saving, ECT is regarded as a strongly controversial treatment and stigmatization is frequently mentioned in relation to it. However, no systematic research in this area has taken place so far. AIM: The aim of this qualitative study was to explore the experiences and attitudes of former recipients of ECT and of experts professionally involved with ECT in order to identify potential stigmatization...
May 14, 2018: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/29757318/use-of-protective-behavioral-strategies-among-young-adult-veteran-marijuana-users
#2
Eric R Pedersen, Margo C Villarosa-Hurlocker, Mark A Prince
Young adult veterans are at risk for problematic marijuana use and associated consequences, which is partially due to their high rates of Posttraumatic Stress Disorder (PTSD), depression, and problematic substance use. Veterans tend to endorse more severe and chronic mental health symptoms compared to their civilian counterparts and they identify marijuana use as a method to cope with their symptoms. Given the prevalence of marijuana use among veterans in the community and in clinical settings, it is important to explore the factors that may help minimize harm associated with use for those that choose to use the drug...
January 2018: Cannabis
https://www.readbyqxmd.com/read/29756519/adipose-derived-stem-cells-stimulated-with-n-butylidenephthalide-exhibit-therapeutic-effects-in-a-mouse-model-of-parkinson-s-disease
#3
Kang Chi, Ru-Huei Fu, Yu-Chuen Huang, Shih-Yin Chen, Ching-Ju Hsu, Shinn-Zong Lin, Chi-Tang Tu, Li-Hsun Chang, Ping-An Wu, Shih-Ping Liu
Parkinson's disease (PD) causes motor dysfunction and dopaminergic cell death. Drug treatments can effectively reduce symptoms but often cause unwanted side effects. Stem cell therapies using cell replacement or indirect beneficial secretomes have recently emerged as potential therapeutic strategies. Although various types of stem cells have been proposed as possible candidates, adipose-derived stem cells (ADSCs) are easily obtainable, more abundant, less ethically disputed, and able to differentiate into multiple cell lineages...
January 1, 2018: Cell Transplantation
https://www.readbyqxmd.com/read/29755339/therapeutic-potential-of-a-prolyl-hydroxylase-inhibitor-fg-4592-for-parkinson-s-diseases-in-vitro-and-in-vivo-regulation-of-redox-biology-and-mitochondrial-function
#4
Xuan Li, Xin-Xin Cui, Ya-Jing Chen, Ting-Ting Wu, Huaxi Xu, Huiyong Yin, Yun-Cheng Wu
As the main transcription factor that regulates the cellular responses to hypoxia, Hypoxia-inducible factor-1α (HIF-1α) plays an important role in the pathogenesis of Parkinson's disease (PD). HIF-1α is normally degraded through ubiquitination after hydroxylation by prolyl hydroxylases (PHD). Emerging evidence has suggested that HIF PHD inhibitors (HIF-PHI) may have neuroprotective effects on PD through increasing HIF-1α levels. However, the therapeutic benefit of HIF-PHI for PD remains poorly explored due to the lack of proper clinical compounds and understanding of the underlying molecular mechanisms...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29755054/cervical-cancer-screening-among-underscreened-and-unscreened-brazilian-women-training-community-health-workers-to-be-agents-of-change
#5
Nádia Kienen, Lorna Bittencourt, Sandra M Pelloso, Marcia E Consolaro, Philip E Castle, Edward E Partridge, Nia R Silva, Isabel C Scarinci
BACKGROUND: Despite the availability of cervical cancer screening programs in Brazil, some women do not participate in these programs owing to structural and/or interpersonal/intrapersonal barriers, resulting in high cervical cancer incidence and mortality. Integrating community health workers (CHWs) into the delivery of cervical cancer screening interventions is potentially a feasible strategy to address these barriers. OBJECTIVES: This study aimed to implement and evaluate a CHW training to deliver a brief intervention to promote cervical cancer screening among underscreened and unscreened women in Brazil...
2018: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/29753729/controlled-microenvironments-to-evaluate-chemotactic-properties-of-cultured-m%C3%A3-ller-glia
#6
Juan Pena, Nihan Dulger, Tanya Singh, Jing Zhou, Robert Majeska, Stephen Redenti, Maribel Vazquez
Emerging therapies have begun to evaluate the abilities of Müller glial cells (MGCs) to protect and/or regenerate neurons following retina injury. The migration of donor cells is central to many reparative strategies, where cells must achieve appropriate positioning to facilitate localized repair. Although chemical cues have been implicated in the MGC migratory responses of numerous retinopathies, MGC-based therapies have yet to explore the extent to which external biochemical stimuli can direct MGC behavior...
May 10, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29746177/exploration-of-effective-persuasive-strategies-used-in-resisting-product-advertising-a-case-study-of-adult-health-check-ups
#7
Han-Kuang Tien, Wen Chung
This research addressed adults' health check-ups through the lens of Role Transportation Theory. This theory is applied to narrative advertising that lures adults into seeking health check-ups by causing audiences to empathize with the advertisement's character. This study explored the persuasive mechanism behind narrative advertising and reinforced the Protection Motivation Theory model. We added two key perturbation variables: optimistic bias and truth avoidance. To complete the verification hypothesis, we performed two experiments...
May 10, 2018: Health Communication
https://www.readbyqxmd.com/read/29745418/setting-the-research-agenda-for-induced-abortion-in-africa-and-asia
#8
Rachel H Scott, Veronique Filippi, Ann M Moore, Rajib Acharya, Akinrinola Bankole, Clara Calvert, Kathryn Church, Jenny A Cresswell, Katharine Footman, Joanne Gleason, Kazuyo Machiyama, Cicely Marston, Mike Mbizvo, Maurice Musheke, Onikepe Owolabi, Jennifer Palmer, Christopher Smith, Katerini Storeng, Felicia Yeung
Provision of safe abortion is widely recognized as vital to addressing the health and wellbeing of populations. Research on abortion is essential to meet the UN Sustainable Development Goals. Researchers in population health from university, policy, and practitioner contexts working on two multidisciplinary projects on family planning and safe abortion in Africa and Asia were brought together for a workshop to discuss the future research agenda on induced abortion. Research on care-seeking behavior, supply of abortion care services, and the global and national policy context will help improve access to and experiences of safe abortion services...
May 10, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29740981/buzz-pollination-in-neotropical-bees-genus-dependent-frequencies-and-lack-of-optimal-frequency-for-pollen-release
#9
Conrado Augusto Rosi-Denadai, Priscila Cássia Souza Araújo, Lucio Antônio de Oliveira Campos, Lirio Cosme, Raul Narciso Carvalho Guedes
Over 50 genera of bees release pollen from flower anthers using thoracic vibrations, a phenomenon known as buzz-pollination. The efficiency of this process is directly affected by the mechanical properties of the buzzes, namely the duration, amplitude and frequency. Nonetheless, although the effects of the former two properties are well described, the role of buzz frequency on pollen release remains unclear. Furthermore, nearly all of the existing studies describing vibrational properties of natural buzz-pollination are limited to bumblebees (Bombus) and carpenter bees (Xylocopa) constraining our current understanding of this behavior and its evolution...
May 8, 2018: Insect Science
https://www.readbyqxmd.com/read/29740637/a-randomized-efficacy-trial-of-a-cognitive-behavioral-group-intervention-to-prevent-internet-use-disorder-onset-in-adolescents-the-protect-study-protocol
#10
Katajun Lindenberg, Katharina Halasy, Sophie Schoenmaekers
Background: The reduction of prevalence rates of Internet Use Disorder (IUD) and its effective treatment are at high priority in both public health and educational policies. School-based preventive interventions facilitate a low-threshold approach for individuals with IUD, who are typically characterized by high therapy avoidance. Moreover, indicated approaches which target adolescents at high-risk show larger effects than universal prevention programs. Simultaneously, they reduce unnecessary burden for the majority of high-school students that is not at-risk...
June 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29734674/a-cross-disciplinary-successful-aging-intervention-and-evaluation-comparison-of-person-to-person-and-digital-assisted-approaches
#11
Hui-Chuan Hsu, Tsuann Kuo, Ju-Ping Lin, Wei-Chung Hsu, Chia-Wen Yu, Yen-Cheng Chen, Wan-Zhen Xie, Wei-Chiang Hsu, Ya-Lan Hsu, Mu-Ting Yu
Background : Successful aging has been the paradigm of old-age life. The purpose of this study was to implement and evaluate a cross-disciplinary intervention program using two approaches for community-based older adults in Taichung, Taiwan. Methods : The content of the intervention included successful aging concepts and preparation, physical activity, chronic disease and health management, dietary and nutrition information, cognitive training, emotional awareness and coping skills, family relationship and resilience, legal concepts regarding financial protection, and Internet use...
May 4, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29729050/staff-members-ambivalence-on-caring-for-patients-with-multidrug-resistant-bacteria-at-their-end-of-life-a-qualitative-study
#12
Johanna M Tiedtke, Stephanie Stiel, Maria Heckel, Franziska A Herbst, Alexander Sturm, Cornel Sieber, Christoph Ostgathe, Frieder R Lang
AIMS AND OBJECTIVES: To explore healthcare professionals' personal experiences, feelings, and attitudes about caring for hospitalized patients with multidrug-resistant bacteria in palliative and geriatric care. BACKGROUND: Working in end-of-life care involves at times burdening demands that affect not only healthcare professionals personally but also their actions. It is suggested that multidrug-resistant bacteria and their consequences for colonized or infected patients in hospitals are among the challenges for all professionals in end-of-life care...
May 5, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29727637/personal-behavioral-and-environmental-predictors-of-healthy-weight-maintenance-during-the-transition-to-adulthood
#13
Nicole Larson, Ying Chen, Melanie Wall, Megan R Winkler, Andrea B Goldschmit, Dianne Neumark-Sztainer
There is a high prevalence of overweight among U.S. young adults and the intergenerational implications of excess weight gain at this life stage are great. We used Project EAT (Eating and Activity in Teens and Young Adults) study data to identify personal, behavioral, and environmental factors that predicted healthy weight maintenance during the transition from adolescence to adulthood and as individuals progressed from the third to fourth decade of life. The sample included 1120 young adults who were secondary school students in Minneapolis-St...
May 1, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29723908/-impact-of-emotion-regulation-and-emotional-arousal-on-quality-of-life-and-adherence-of-couples-after-kidney-transplantation
#14
Luisa Peters, Laura Franke, Daria Tkachenko, Mario Schiffer, Tanja Zimmermann
INTRODUCTION: Nonadherence to immunosuppressive medication increases the risk of graft failure. Maladaptive emotion regulation strategies (ERS) seem to be a risk factor for nonadherence, whereas for patients in relationships spousal support appears as a protective resource. Emotional arousal, objectively measured by the fundamental frequency (f0 ) during spousal supportive communication is associated with supportive behavior. MATERIALS & METHODS: This study examined the relationship between beliefs about immunosuppressive medication, quality of life, ERS, emotions and emotional arousal, assessed during social support interactions of both spouses of N=50 couples after kidney transplantation...
May 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29723547/hyperglycemia-elicits-anxiety-like-behaviors-in-zebrafish-protective-role-of-dietary-diphenyl-diselenide
#15
Matheus M Dos Santos, Gabriel T de Macedo, Alessandro S Prestes, Vânia L Loro, Graciela M Heidrich, Rochele S Picoloto, Denis B Rosemberg, Nilda V Barbosa
Diabetes mellitus (DM) is a chronic metabolic disease that may comorbid with various psychiatric disorders, such as anxiety and depression. The search for effective therapeutics to alleviate hyperglycemia and complications resulting from DM is continuous. Here we investigate the effects of diphenyl diselenide (DD), an organoselenium compound with several pharmacological properties, in a zebrafish model of hyperglycemia. Fish were fed for 74 days with a diet containing 3 mg/Kg DD, a concentration chosen after experiments based in a dose-response curve (DD 1, 2 and 3 mg/Kg) that did not cause overt toxicity (mortality, weight loss and neurobehavioral deficits)...
April 30, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29721626/-individual-prevention-of-occupational-contact-dermatitis-protective-gloves-and-skin-protection-recommendations-as-part-of-the-patient-management-scheme-by-the-public-statutory-employers-liability-insurance
#16
REVIEW
A Wilke, C Skudlik, F K Sonsmann
The dermatologist's procedure is a pivotal tool for early recognition of occupational contact dermatitis (OCD), for reporting OCD cases to the statutory accident insurance and for treating the diseases. The employer is in charge of implementing skin protection measures at the workplace. However, in terms of an individual prevention approach it may be necessary to propose targeted skin protection recommendations in specific patient cases. The patient's own skin protection behavior significantly contributes to regenerating and maintaining healthy skin...
May 2, 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29719246/scaling-up-cortical-control-inhibits-pain
#17
Jahrane Dale, Haocheng Zhou, Qiaosheng Zhang, Erik Martinez, Sile Hu, Kevin Liu, Louise Urien, Zhe Chen, Jing Wang
Acute pain evokes protective neural and behavioral responses. Chronic pain, however, disrupts normal nociceptive processing. The prefrontal cortex (PFC) is known to exert top-down regulation of sensory inputs; unfortunately, how individual PFC neurons respond to an acute pain signal is not well characterized. We found that neurons in the prelimbic region of the PFC increased firing rates of the neurons after noxious stimulations in free-moving rats. Chronic pain, however, suppressed both basal spontaneous and pain-evoked firing rates...
May 1, 2018: Cell Reports
https://www.readbyqxmd.com/read/29717391/parental-restriction-of-movie-viewing-prospectively-predicts-adolescent-alcohol-and-marijuana-initiation-implications-for-media-literacy-programs
#18
Melissa J Cox, Joy Gabrielli, Tim Janssen, Kristina M Jackson
Youth are heavy consumers of media, and exposure to mature media content is associated with initiation and progression of substance use. Parental restriction of such content has been shown to be an effective mechanism to reduce negative consequences attributed to exposure to mature media content. This study assessed the influence of parental restriction of movie watching across Motion Picture Association of America rating categories on subsequent alcohol and marijuana initiation at 1- and 2-year follow-up. Using data from a longitudinal study of adolescent substance use (N = 1023), we used logistic regression analyses to determine the odds of alcohol and marijuana initiation across movie rating categories, within R-rated restriction categories in particular, and based on changes in parental restriction of movies over time...
May 2, 2018: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29716586/access-to-health-care-for-uninsured-latina-immigrants-in-south-carolina
#19
John S Luque, Grace Soulen, Caroline B Davila, Kathleen Cartmell
BACKGROUND: South Carolina is considered a "new destination" state for Latino immigrants. Language barriers, transportation difficulties, low socioeconomic status, inflexible work schedules, different cultural norms, and anxiety and fear related to the current anti-immigrant political climate all negatively impact Latino immigrants' frequency of contact with the health care system, and consequently they suffer poor health outcomes. The study objective was to explore uninsured Latina immigrant women's access to health care and alternative treatment strategies in coastal South Carolina...
May 2, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29708460/weighing-the-pros-and-cons-of-using-alcohol-protective-behavioral-strategies-a-qualitative-examination-among-college-students
#20
Adrian J Bravo, Matthew R Pearson, Leah E Stevens, James M Henson
BACKGROUND: Alcohol protective behavioral strategies (PBS) are behaviors engaged in immediately prior to, during, after, or instead of drinking with the explicit goal of reducing alcohol use, intoxication, and/or alcohol-related harms. Despite the quantitative support for alcohol PBS as a protective factor among college student drinkers, we know of no qualitative research aimed at determining college student drinkers' perceptions regarding the advantages and disadvantages of using PBS...
April 30, 2018: Substance Use & Misuse
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