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https://www.readbyqxmd.com/read/28342926/causes-and-clinical-features-of-infertile-men-with-non-obstructive-azoospermia-and-histopathological-diagnosis-of-hypospermatogenesis
#1
Yu-Sheng Cheng, Chun-Wun Lu, Tsung-Yen Lin, Pei-Yu Lin, Yung-Ming Lin
OBJECTIVE: To analyze the causes and the clinical features of infertile men with non-obstructive azoospermia (NOA) and hypospermatogenesis (HS). METHODS: This retrospective cohort study included 100 patients with NOA and HS and eight patients with obstructive azoospermia and normal spermatogenesis. The severity of HS was subdivided into three groups (mild, moderate, and severe) based on spermatogenic score. Data of history, physical findings, serum hormone profiles, genetic studies and sperm retrieval rate (SRR) were collected...
March 22, 2017: Urology
https://www.readbyqxmd.com/read/28327434/-99m-tc-3prgd2-scintigraphy-to-stage-liver-fibrosis-and-evaluate-reversal-after-fibrotic-stimulus-withdrawn
#2
Xin Zhang, Qiyong Guo, Yu Shi, Weina Xu, Shupeng Yu, Zhiguang Yang, Li Cao, Changping Liu, Zhoushe Zhao, Jun Xin
OBJECTIVE: Scintigraphy using 99mTc-3PRGD2 targeting integrin αvβ3 could assess activation of hepatic stellate cells (HSCs). Liver fibrogenesis is intimately associated with activation of HSCs, and the fibrolytic process is accompanied by the reduction of the activated HSCs. In this study, we aimed to evaluate the feasibility of this method to assess the severity of liver fibrosis and the reversal after the fibrotic stimulus withdrawal. METHODS: Liver fibrosis of different stages was induced by thioacetamide (TAA) injection for 2, 4 and 6 weeks (n = 6 for each time point)...
March 7, 2017: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/28321651/effects-of-strontium-ranelate-treatment-on-osteoblasts-cultivated-onto-scaffolds-of-trabeculae-bovine-bone
#3
Gerluza Aparecida Borges Silva, Bruno Machado Bertassoli, Cristiane Aparecida Sousa, Juliano Douglas Albergaria, Rayan Silva de Paula, Erika Cristina Jorge
Blocks of Bovine bone have shown promising results as implantable scaffolds to promote bone regeneration. Strontium ranelate (SrR) is both an antiresorptive and an anabolic drug that has been indicated for oral administration to treat osteoporosis. Few studies, however, have investigated the local effects of SrR and its use in association with biomaterials thus far. In this work, we investigated SrR effects in cultures of primary osteoblasts (PO, from Wistar rats calvaria) and immortalized osteoblasts (IO, from MC3T3-E1 cell line) cultivated as a monolayer or in association with scaffolds of bovine bone in mineralized (MBB) and demineralized (DBB) forms...
March 20, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28317347/-effects-of-strontium-ranelate-on-the-rats-palatal-suture-after-rapid-maxillary-expansion
#4
Kong Chao, Wang Xuxia, Wang Qianqian, Han Yuanyuan, Zhao Shuya, Zhang Jun
OBJECTIVE: This study investigated the effects of strontium ranelate (SrR) on the rats' palatal suture after rapid maxillary expansion (RME). METHODS: Thirty-six male 6-week-old Wistar rats were randomly divided into three groups: control group (A), expansion only group (B), and expansion plus SrR group (C). Each group comprised 12 rats. Neither expansion nor SrR was given to group A. Each rat in groups B and C was set an orthodontic appliance with an initial expansive force of 1 N...
August 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28301790/human-papillomavirus-vaccination-and-genital-warts-in-young-indigenous-australians-national-sentinel-surveillance-data
#5
Hammad Ali, Hamish McManus, Catherine C O'Connor, Denton Callander, Marlene Kong, Simon Graham, Dina Saulo, Christopher K Fairley, David G Regan, Andrew Grulich, Nicola Low, Rebecca J Guy, Basil Donovan
OBJECTIVES: To examine the impact of the national human papillomavirus (HPV) vaccination program (available to girls and women [12-26 years] since 2007 and to boys [12-15 years] since 2013) on the number of diagnoses of genital warts in Australian Aboriginal and Torres Strait Islander (Indigenous) people. DESIGN, SETTING, PARTICIPANTS: Analysis of routinely collected data from patients attending 39 sexual health clinics (SHCs) in the Genital Warts Surveillance Network for the first time...
March 20, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28268346/theranostic-microwave-applicator-suitable-for-minimal-invasive-therapy-of-malignant-tissue
#6
Carolin Reimann, Margarita Puentes, Martin Schusler, Frank Hubner, Babak Bazrafshan, Thomas J Vogl, Rolf Jakoby
A microwave applicator is presented that realizes the theranostic approach by providing two operation modes to detect and treat tumor cells, exemplary in the liver. The tool is based on a planar sensor structure with Split Ring Resonators (SRR) as key elements. For the detection, changes in dielectric properties caused by tissue abnormalities are evaluated by analyzing shifts in the resonance frequency of the SRR. For the treatment mode, the input power is amplified to the specific resonance frequency and microwave ablation is performed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28252000/homodyne-detection-of-short-range-doppler-radar-using-a-forced-oscillator-model
#7
Kunanon Kittipute, Peerayudh Saratayon, Suthasin Srisook, Paramote Wardkein
This article presents the homodyne detection in a self-oscillation system, which represented by a short-range radar (SRR) circuit, that is analysed using a multi-time forced oscillator (MTFO) model. The MTFO model is based on a forced oscillation perspective with the signal and system theory, a second-order differential equation, and the multiple time variable technique. This model can also apply to analyse the homodyne phenomenon in a difference kind of the oscillation system under same method such as the self-oscillation system, and the natural oscillation system with external forced...
March 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28226507/theranostic-microwave-applicator-suitable-for-minimal-invasive-therapy-of-malignant-tissue
#8
Carolin Reimann, Margarita Puentes, Martin Schusler, Frank Hubner, Babak Bazrafshan, Thomas J Vogl, Rolf Jakoby, Carolin Reimann, Margarita Puentes, Martin Schusler, Frank Hubner, Babak Bazrafshan, Thomas J Vogl, Rolf Jakoby, Rolf Jakoby, Carolin Reimann, Babak Bazrafshan, Thomas J Vogl, Frank Hubner, Margarita Puentes
A microwave applicator is presented that realizes the theranostic approach by providing two operation modes to detect and treat tumor cells, exemplary in the liver. The tool is based on a planar sensor structure with Split Ring Resonators (SRR) as key elements. For the detection, changes in dielectric properties caused by tissue abnormalities are evaluated by analyzing shifts in the resonance frequency of the SRR. For the treatment mode, the input power is amplified to the specific resonance frequency and microwave ablation is performed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225328/srr-winter-2016-abstracts
#9
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28225327/srr-summer-2016-abstracts
#10
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28223125/different-doses-of-strontium-ranelate-and-mechanical-vibration-modulate-distinct-responses-in-the-articular-cartilage-of-ovariectomized-rats
#11
A G H Mierzwa, J F Campos, M F Jesus, H B Nader, M Lazaretti-Castro, R D Reginato
OBJECTIVE: To investigate the effects of different strontium ranelate (SrR) doses alone or in combination with low-intensity and high-frequency mechanical vibration (MV) on articular cartilage in ovariectomized rats. DESIGN: Fifty 6-month-old female Wistar rats underwent ovariectomy (OVX) and after 3 months were divided into: control group (Control); SrR 300 mg/kg/day (SrR300); SrR 625 mg/kg/day (SrR625); MV; SrR 625 mg/kg/day plus MV (SrR625 + MV). The vehicle and the SrR were administered by gavage 7 days/week and vibration (0...
February 20, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28196329/breastfeeding-mode-and-risk-of-breast-cancer
#12
Mishel Unar-Munguía, Gabriela Torres-Mejía, M Arantxa Colchero, Teresita González de Cosío
BACKGROUND: Breastfeeding reduces women's risk of breast cancer. Since exclusive breastfeeding has a stronger hormonal effect, it could theoretically result in a greater reduction in breast cancer risk than any breastfeeding mode. No meta-analysis has examined breast cancer risk by breastfeeding mode. Research aim: The authors conducted a meta-analysis for breast cancer risk in parous women who breastfed exclusively or in any mode versus parous women who formula fed their infants, and they estimated the summary dose-response association by the accumulated duration of any breastfeeding mode...
February 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28187786/low-renal-replacement-therapy-incidence-among-slowly-progressing-elderly-chronic-kidney-disease-patients-referred-to-nephrology-care-an-observational-study
#13
Ulrika Hahn Lundström, Alessandro Gasparini, Rino Bellocco, Abdul Rashid Qureshi, Juan-Jesus Carrero, Marie Evans
BACKGROUND: Elderly patients with advanced chronic kidney disease (CKD) have a high risk of death before reaching end-stage kidney disease. In order to allocate resources, such as advanced care nephrology where it is most needed, it is essential to know which patients have the highest absolute risk of advancing to renal replacement therapy (RRT). METHODS: We included all nephrology-referred CKD stage 3b-5 patients in Sweden 2005-2011 included in the Swedish renal registry (SRR-CKD) who had at least two serum creatinine measurements one year apart (+/- 6 months)...
February 10, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28094052/the-association-of-cancer-risks-with-pentachlorophenol-exposure-focusing-on-community-population-in-the-areas-along-certain-section-of-yangtze-river-in-china
#14
Yanjie Cui, Ling Liang, Qi Zhong, Qian He, Xiaomei Shan, Keyang Chen, Fen Huang
Pentachlorophenol (PCP) was used in large quantities, and mainly for killing the intermediate host snails of schistosome in China, thereby resulting in ubiquitous PCP residue in the environment. However, studies considering the carcinogenicity of PCP for humans mainly focused on occupational workers, and the actual carcinogenicity of PCP for general population is uncertain. To investigate the association between cancer risks and PCP exposure in a community population, an ecological study was conducted in three contaminated areas along the Yangtze River...
January 13, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28092725/strontium-ranelate-a-promising-disease-modifying-osteoarthritis-drug
#15
REVIEW
Weiyu Han, Shicai Fan, Xiaochun Bai, Changhai Ding
The articular cartilage and subchondral bone may have potential crosstalk in the development and progression of osteoarthritis (OA). Strontium ranelate (SrR) has the ability to dissociate the bone remodeling process and to change the balance between bone resorption and bone formation. Its effect on subchondral bone makes it a potential disease- modifying osteoarthritis drug (DMOAD) in the treatment of OA. The aim of the current review is to summarize up-to-date pharmacological and clinical data of SrR for OA treatment...
March 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/28078921/regional-differences-in-mortality-hospital-discharges-and-primary-care-contacts-for-cardiovascular-disease
#16
Sigridur Haraldsdottir, Sigurdur Gudmundsson, Guđmundur Thorgeirsson, Sigrun H Lund, Unnur A Valdimarsdottir
AIMS: Surveillance of geographical variations in cardiovascular health is important in order to achieve the objectives of reducing regional health disparities. We aimed to explore differences in cardiovascular disease (CVD) mortality and prevalence of CVD diagnoses made in primary and in-patient care, as well as risk factor distribution by geographic regions (urban/rural) in Iceland. METHODS: From nationwide health registers, we obtained data on CVD mortalities ( N = 7113), primary healthcare CVD contacts ( N = 58,246) and hospital CVD discharges ( N = 14,039), as well as data on CVD risk factors from a national health survey ( N = 5909; response rate 60...
January 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28067550/association-between-consumption-of-soy-and-risk-of-cardiovascular-disease-a-meta-analysis-of-observational-studies
#17
Zhaoli Yan, Xinyue Zhang, Chunlin Li, Shouchun Jiao, Wenyao Dong
Background The relationships between dietary intake of soy foods and risk of cardiovascular disease are uncertain. The aims of this study were to evaluate and summarize the evidence on the association between consumption of soy and risk of cardiovascular disease (including stroke and coronary heart disease). Methods We systematically searched the MEDLINE and EMBASE databases from their inception up to 22 February 2016. We included only observational studies, and used random-effects models to calculate summary relative risks (SRRs) and 95% confidence intervals (CIs)...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28059401/single-sideband-photonic-microwave-generation-with-an-optically-injected-quantum-dot-semiconductor-laser
#18
Chih-Ying Chen, Chih-Hao Cheng, Fan-Yi Lin
We studied single-sideband (SSB) photonic microwave generation with a high sideband rejection ratio (SRR) based on the period-one dynamical states of an optically injected quantum-dot (QD) semiconductor laser and demonstrated that the SSB signals have SRRs of approximately 15 dB higher than those generated with a conventional quantum-well semiconductor laser under conditions of optimal microwave power. The enhancement of SRR in the QD laser, which is important in mitigating the power penalty effect in applications such as radio-over-fiber optical communications, could be primarily attributed to a lower carrier decay rate in the dots, smaller linewidth enhancement factor, and reduced photon decay rate...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28059143/influence-of-coronary-artery-disease-and-subclinical-atherosclerosis-related-polymorphisms-on-the-risk-of-atherosclerosis-in-rheumatoid-arthritis
#19
Raquel López-Mejías, Alfonso Corrales, Esther Vicente, Montserrat Robustillo-Villarino, Carlos González-Juanatey, Javier Llorca, Fernanda Genre, Sara Remuzgo-Martínez, Trinidad Dierssen-Sotos, José A Miranda-Filloy, Marco A Ramírez Huaranga, Trinitario Pina, Ricardo Blanco, Juan J Alegre-Sancho, Enrique Raya, Verónica Mijares, Begoña Ubilla, Iván Ferraz-Amaro, Carmen Gómez-Vaquero, Alejandro Balsa, Francisco J López-Longo, Patricia Carreira, Isidoro González-Álvaro, J Gonzalo Ocejo-Vinyals, Luis Rodríguez-Rodríguez, Benjamín Fernández-Gutiérrez, Santos Castañeda, Javier Martín, Miguel A González-Gay
A genetic component influences the development of atherosclerosis in the general population and also in rheumatoid arthritis (RA). However, genetic polymorphisms associated with atherosclerosis in the general population are not always involved in the development of cardiovascular disease (CVD) in RA. Accordingly, a study in North-American RA patients did not show the association reported in the general population of coronary artery disease with a series of relevant polymorphisms (TCF21, LPA, HHIPL1, RASD1-PEMT, MRPS6, CYP17A1-CNNM2-NT5C2, SMG6-SRR, PHACTR1, WDR12 and COL4A1-COL4A2)...
January 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28052066/effects-of-strontium-ranelate-on-spinal-interbody-fusion-surgery-in-an-osteoporotic-rat-model
#20
Tsung-Ting Tsai, Ching-Lung Tai, Natalie Yi-Ju Ho, Po-Liang Lai, Tsai-Sheng Fu, Chi-Chien Niu, Lih-Huei Chen, Wen-Jer Chen
Osteoporosis is a bone disease that afflicts millions of people around the world, and a variety of spinal integrity issues, such as degenerative spinal stenosis and spondylolisthesis, are frequently concomitant with osteoporosis and are sometimes treated with spinal interbody fusion surgery. Previous studies have demonstrated the efficacy of strontium ranelate (SrR) treatment of osteoporosis in improving bone strength, promoting bone remodeling, and reducing the risk of fractures, but its effects on interbody fusion surgery have not been adequately investigated...
2017: PloS One
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