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https://www.readbyqxmd.com/read/29046817/fertility-with-early-reduction-of-ovarian-reserve-the-last-straw-that-breaks-the-camel-s-back
#1
REVIEW
Sabahat Rasool, Duru Shah
Diminished fertility and poor ovarian response pose a conundrum to the experts in the field of reproductive medicine. There is limited knowledge about the risk factors of diminished ovarian reserve other than the iatrogenic ones. One of the leading causes of infertility in women today is diminished ovarian reserve (DOR). DOR is characterized by a low number of eggs in a woman's ovaries and/or with poor quality of the remaining eggs, which boils down to impaired development of the existing eggs, even with assisted reproductive techniques...
2017: Fertility Research and Practice
https://www.readbyqxmd.com/read/29045988/postgraduate-experiences-with-an-advanced-reproductive-health-and-abortion-training-and-leadership-program
#2
Alison Block, Christine Dehlendorf, M Antonia Biggs, Sarah McNeil, Suzan Goodman
BACKGROUND AND OBJECTIVES: Family physicians are critical to reproductive health service provision including miscarriage management and abortion care, but many graduates report barriers in integrating these services into practice. We designed and implemented CREATE (Continuing Reproductive Education for Advanced Training Efficacy), an elective advanced training and leadership program for senior residents aimed to help new graduates integrate miscarriage and abortion care into practice...
October 2017: Family Medicine
https://www.readbyqxmd.com/read/29043701/royal-jelly-promotes-ovarian-follicles-growth-and-increases-steroid-hormones-in-immature-rats
#3
Elham Ghanbari, Mohammad Rasool Khazaei, Mozafar Khazaei, Vahid Nejati
Background: Royal jelly (RJ) is a complementary diet widely prescribed by traditional medicine specialists for treatment of infertility. The aim of present study was to evaluate the effects of RJ on a set of reproductive parameters in immature female rats. MATERIALS AND METHODS: In this experimental study, thirty two immature female rats (30-35 g) were divided into four groups (n=8/group): three experimental groups and one control. The experimental groups received 100, 200 and 400 mg/kg/body weight doses of RJ daily for 14 days, and the control group received 0...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29040606/pinopode-score-around-the-time-of-implantation-is-predictive-of-successful-implantation-following-frozen-embryo-transfer-in-hormone-replacement-cycles
#4
X Y Jin, L J Zhao, D H Luo, L Liu, Y D Dai, X X Hu, Y Y Wang, X Lin, F Hong, T C Li, S Y Zhang
STUDY QUESTION: Is pinopode measurement of any prognostic value? SUMMARY ANSWER: Pinopode expression was significantly associated with the occurrence of pregnancy after frozen embryo transfer. WHAT IS KNOWN ALREADY: Pinopodes are expressed in the endometrium during the implantation period. Pinopode measurement has been proposed as a marker of endometrial receptivity. STUDY DESIGN, SIZE, DURATION: A prospective cohort study was conducted at the Center of Reproductive Medicine, Sir Run Run Shaw Hospital, between 2014 and 2016, recruiting 172 women with infertility and undergoing frozen embryo transfer following IVF treatment...
October 13, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29034509/3d-diffusion-weighted-129-xe-mri-for-whole-lung-morphometry
#5
Ho-Fung Chan, Neil J Stewart, Graham Norquay, Guilhem J Collier, Jim M Wild
PURPOSE: To obtain whole lung morphometry measurements from (129) Xe in a single breath-hold with 3D multiple b-value (129) Xe diffusion-weighted MRI (DW-MRI) with an empirically optimized diffusion time and compressed sensing for scan acceleration. METHODS: Prospective three-fold undersampled 3D multiple b-value hyperpolarized (129) Xe DW-MRI datasets were acquired, and the diffusion time (Δ) was iterated so as to provide diffusive length scale (LmD ) estimates from the stretched exponential model (SEM) that are comparable to those from (3) He...
October 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29034472/protective-effects-of-curcumin-against-aflatoxicosis-a-comprehensive-review
#6
REVIEW
Mohammad Mohajeri, Behzad Behnam, Arrigo F G Cicero, Amirhossein Sahebkar
Aflatoxicosis is a deleterious medical condition that results from aflatoxins (AFs) or ochratoxins (OTs). Contamination with these toxins exerts detrimental effects on the liver, kidneys, reproductive organs, and also on immunological and cardiovascular systems. Aflatoxicosis is closely associated with overproduction of reactive oxygen species (ROS) as key contributors to oxidative and nitrosative stress responses, and subsequent damages to lipids, proteins, RNA, and DNA. The main target organ for AF toxicity is the liver, where DNA adducts, degranulation of endoplasmic reticulum, increased hepatic lipid peroxide, GSH depletion, mitochondrial dysfunction, and reduction of enzymatic and non-enzymatic antioxidants are manifestations of aflatoxicosis...
October 16, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29032167/evaluation-of-embryotoxic-and-teratogenic-effects-of-the-oil-extracted-from-caryocar-brasiliense-cambess-pulp-in-rats
#7
Giseli Karenina Traesel, Fernando Freitas de Lima, Ariany Carvalho Dos Santos, Roosevelt Isaias Carvalho Souza, Daniela Torres Cantadori, Carlos Roberto Kretschmer, Vinicius João Navarini, Silvia Aparecida Oesterreich
The objective of this study was to evaluate the maternal, embryotoxic and teratogenic effects of Caryocar brasiliense pulp oil (OPCB), oil widely used in Brazilian cuisine and traditional medicine. Pregnant Wistar female rats were used in this study for three treatment groups (250, 500 and 1000 mg/kg/day) and a control group. The OPCB was administered orally throughout the period of organogenesis of females (6th until the 15th day of gestation). The pregnant females were gross necropsied on d20, followed by maternal and fetus examination, to evaluate the teratogenicity, reproductive and developmental performance of OPCB...
October 12, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29025019/differing-molecular-response-of-young-and-advanced-maternal-age-human-oocytes-to-ivm
#8
J M Reyes, E Silva, J L Chitwood, W B Schoolcraft, R L Krisher, P J Ross
STUDY QUESTION: What effect does maternal age have on the human oocyte's molecular response to in vitro oocyte maturation? SUMMARY ANSWER: Although polyadenylated transcript abundance is similar between young and advanced maternal age (AMA) germinal vesicle (GV) oocytes, metaphase II (MII) oocytes exhibit a divergent transcriptome resulting from a differential response to in vitro oocyte maturation. WHAT IS KNOWN ALREADY: Microarray studies considering maternal age or maturation stage have shown that either of these factors will affect oocyte polyadenylated transcript abundance in human oocytes...
September 15, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29024053/direct-effect-of-pholyphenol-rich-plants-rooibos-and-ginkgo-on-porcine-ovarian-cell-functions
#9
A Štochmaľová, A Kádasi, R Alexa, M Bauer, A H Harrath, A V Sirotkin
The polyphenol-rich plants rooibos and ginkgo are widely used in folk medicine and in preparation of foods and drinks, but their effect on reproduction has not been properly studied yet. The aim of our in vitro experiments was to examine the possible direct effect of rooibos and ginkgo on the basic ovarian cell functions-proliferation, apoptosis and release of hormones progesterone (P4) and leptin (L). Porcine ovarian granulosa cells were cultured in the presence of rooibos or ginkgo extract (0, 1, 10 and 100 μg/ml of medium)...
October 11, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29020788/-complete-molar-pregancy-with-development-of-non-metastatic-persistent-trophoblastic-diseasea-case-report-reflection-of-rules-of-care-and-decision-making-processes-forensic-responsibility-and-the-position-of-doctor-in-the-general-gynecologic-and-obstetric-outpatient
#10
S Zeman, P Trávník, K Dvořáková, J Zemanová
OBJECTIVE: To define the forensic responsibility and the position of doctor in the general gynecologic and obstetric outpatient practice in care of the complete molar pregancy. DESIGN: Case report and review article. SETTING: General gynecologic and obstetric outpatient practice Velké Meziříčí; Sanatorium REPROMEDA, Centre of reproductive medicine and preimplantation genetics, Brno; Histopatology department of Hospital Jihlava. CASE REPORT: The changing clinical presentation of complete molar pregnancy with development of non-metastatic gestational trophoblastic disease: management...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/29020785/-how-is-the-czech-oocyte-donor-the-analysis-of-their-profile
#11
T Rumpíková, I Oborná, S Bělašková, D Rumpík
OBJECTIVE: The aim of our study was to investigate (a) the basic socio-demographic characteristics of Czech oocytes donors, (b) their attitudes towards anonymous or nonanonymous donation and (c) their motivations to donate oocytes. DESIGN: Original article. SETTING: Clinic of Reproductive Medicine and Gynecology Zlin. METHODS: A total of 215 oocytes donors participated in this study, which was undertaken in years 2015-2016...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28993030/a-maternal-functional-module-in-the-mammalian-oocyte-to-embryo-transition
#12
REVIEW
Xukun Lu, Zheng Gao, Dandan Qin, Lei Li
Prior to zygotic genome activation, early mammalian development relies on maternal-effect genes to orchestrate the oocyte-to-embryo transition. Recently, a subcortical maternal complex (SCMC) was identified to be essential for mouse preimplantation development. The SCMC integrates multiple proteins encoded by maternal-effect genes and appears to be functionally conserved across mammalian species. In addition, mutations in human SCMC genes are associated with certain human reproductive disorders. Here, we highlight recent advances in the biology of the SCMC and propose that this complex may be a representative example of maternal functional modules in mammalian oocyte-to-embryo transition...
October 6, 2017: Trends in Molecular Medicine
https://www.readbyqxmd.com/read/28992620/potential-ameliorative-effects-of-qing-ye-dan-against-cadmium-induced-prostatic-deficits-via-regulating-nrf-2-ho-1-and-tgf-%C3%AE-1-smad-pathways
#13
Lifen Du, Yongfang Lei, Jinglou Chen, Hongping Song, Xinying Wu
BACKGROUND/AIMS: Cadmium (Cd) is an environmental pollutant with reproductive toxicity. Swertia mileensis is used in Chinese medicine for the treatment of prostatic deficits and named as Qing Ye Dan (QYD). This study was undertaken to investigate the potential protective effects of QYD against Cd-induced prostatic deficits. METHOD: Rat model of prostatic deficits was induced by 0.2 mg/kg/d CdCl2 subcutaneous injection for 15 days. The prostatic oxidative stress was evaluated by detecting the levels of malondialdehyde, nitric oxide, reduced/ oxidized glutathione, total sulfhydryl groups and enzymatic antioxidant status...
October 9, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28986302/activation-of-nrf2-might-reduce-oxidative-stress-in-human-granulosa-cells
#14
Nana Akino, Osamu Wada-Hiraike, Hiromi Terao, Harunori Honjoh, Wataru Isono, Houju Fu, Mana Hirano, Yuichiro Miyamoto, Michihiro Tanikawa, Miyuki Harada, Tetsuya Hirata, Yasushi Hirota, Kaori Koga, Katsutoshi Oda, Kei Kawana, Tomoyuki Fujii, Yutaka Osuga
Nuclear factor-E2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)-antioxidant response element (ARE) signaling pathway is one of the most important defense mechanisms against oxidative stress (OS). It is well documented that equilibration status of OS plays fundamental roles in human reproductive medicine, and the physiological role of Nrf2 in ovarian granulosa cells (GCs) has not been determined yet. Herein we aimed to study the function of Nrf2 in GCs. Human ovarian tissues were subjected to immunohistochemistry to localize Nrf2 and Keap1 and we detected the expression of Nrf2 and Keap1 in the human GCs...
October 4, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28986178/neuropharmacological-and-acute-toxicological-evaluation-of-ethanolic-extract-of-allamanda-cathartica-l-flowers-and-plumieride
#15
Tiago J Bonomini, Iandra Holzmann, Liliani Carolini Thiesen, Eduarda Fratoni, Ana Flavia Fischer Muller, Ruth M Lucinda-Silva, Rosendo Augusto Yunes, Angela Malheiros, Ana Elisa Gonçalves, Ana Paula Dalmagro, Kathryn Ana Bortolini Simão da Silva, Márcia Maria de Souza, José Roberto Santin
Psychiatric diseases affect more than 350 million people all over the world, and medicinal plants have been considered the basis for pharmacological research. The study investigates the anticonvulsant and antidepressant-like activities and acute toxicological effects of ethanolic extract of Allamanda cathartica flowers, and plumieride. The extract was analyzed by HPLC and plumieride was isolated. Toxicity studies were carried out on females Wistar rats (2000 mg/kg). Toxicity was evaluated by measuring biochemical parameters and conducting histopathological analysis...
October 4, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28985293/qualitative-research-on-infertile-chinese-couples-understanding-of-sexuality
#16
Wang Zhuoran, Liu Wanpeng, Peng Tao, Rosemary Coates
Background: Family physicians play an important role in the initial counselling and evaluation of infertility. Despite infertility regarded as a stressor and a life crisis for individuals or couples, little is known about the psychosexual aspects of infertility. On the basis that sexuality is a crucial part of quality of life, it is worthwhile to give more attention to sexuality of infertile couples during their time of experiencing infertility. Objective: This study aimed to gain insight into the dynamic features of the sexuality of infertile couples and to provide meaningful evidence for improving their quality of life...
July 23, 2017: Family Practice
https://www.readbyqxmd.com/read/28985183/the-effect-of-celery-apium-graveolens-l-on-fertility-a-systematic-review
#17
Wesam Kooti, Maryam Moradi, Khadijeh Peyro, Maedeh Sharghi, Fatima Alamiri, Milad Azami, Mohammad Firoozbakht, Mehri Ghafourian
Background Fertility and infertility problems are among the complex issues in medicine. The use of herbal products in the treatment of fertility has been considered as an alternative to synthetic drugs. Celery containing known compounds can have an impact on the fertility rate. The aim of this study was to do a systematic review on conducted studies in conjunction with the celery and reproduction. Methods Required papers were searched from databases like Science direct, PubMed, Scopus, and Springer. Keywords used in this study were "Apium graveolens L...
October 6, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28975776/menopause-and-hormone-replacement-therapy-the-2017-recommendations-of-the-italian-menopause-society
#18
Marco Gambacciani, Nicoletta Biglia, Angelo Cagnacci, Costantino DI Carlo, Salvatore Caruso, Ettore Cicinelli, Vincenzo DE Leo, Manuela Farris, Alessandro Gambera, Secondo Guaschino, Antonio Lanzone, Anna M Paoletti, Novella Russo, Franco Vicariotto, Paola Villa, Annibale Volpe
In the last decade the risk benefits ratio of HRT has been reevaluated mainly in tens of cardiovascular risk. Present Consensus Statement is largely inspired by the Global Consensus on Menopausel Hormone Therapy in 2013 and 2016 by leading global menopause societies (The American Society for Reproductive Medicine, The Asia Pacific Menopause Federation, The Endocrine Society, The European Menopause and Andropause Society, The International Menopause Society, The International Osteoporosis Foundation and The North American Menopause Society)...
October 3, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28973720/a-proteomic-approach-to-guarana-seed-and-pericarp-maturation
#19
A L Souza, J L Lopez-Losano, P C S Angelo, J N Souza-Neto, I B Cordeiro, S Astolfi-Filho, E V Andrade
Paullinia cupana Kunth var. sorbilis (Mart.) Ducke, the cultivated guarana plant, is native to the Amazon and has been valued for its medicinal, stimulant and energetic properties for centuries. The seeds are the main commercial product of the plant and the source of high amounts of purine alkaloids (caffeine and theobromine) and polyphenols (flavonoids, catechins, and tannins). Proteins involved in the development and maturation of guarana fruits in its native habitat are interesting issues for proteomics...
September 21, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28971380/abstracts-for-2017-foundation-for-reproductive-medicine-translational-reproductive-biology-and-clinical-reproductive-endocrinology-conference
#20
(no author information available yet)
No abstract text is available yet for this article.
October 3, 2017: Journal of Assisted Reproduction and Genetics
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