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https://www.readbyqxmd.com/read/28815633/the-gas-that-fuels-the-engine-individuals-motivations-for-medicalisation
#1
Ann V Bell
It is well established that the drivers of medicalisation have shifted alongside changes in the institution of medicine. The process of medicalisation is no longer incited by macro processes of institutional prestige or control; rather, individual patients/consumers are pushing the process forward. The present study complicates this neat transition and examines the relationship between structure and agency using the case of assisted reproductive technology (ART), specifically the medicalisation of lesbian reproduction in the US...
August 16, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28813239/how-should-clinicians-counsel-a-woman-with-a-strong-family-history-of-early-onset-alzheimer-s-disease-about-her-pregnancy
#2
Marianna V Mapes, Barbara M O'Brien, Louise P King
Counseling patients regarding the benefits, harms, and dilemmas of genetic testing is one of the greatest ethical challenges facing reproductive medicine today. With or without test results, clinicians grapple with how to communicate potential genetic risks as patients weigh their reproductive options. Here, we consider a case of a woman with a strong family history of early-onset Alzheimer's disease (EOAD). She is early in her pregnancy and unsure about learning her own genetic status. We address the ethical ramifications of each of her options, which include genetic testing, genetic counseling, and termination versus continuation of the pregnancy...
July 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28811221/is-the-hype-around-the-reproductive-health-claims-of-maca-lepidium-meyenii-walp-justified
#3
REVIEW
Shruti Beharry, Michael Heinrich
ETHNOPHARMACOLOGICAL RELEVANCE: Maca - Lepidium meyenii Walp has been cultivated and used by Andean people for over 1,300 to 2000 years in Peru as food and medicine. Starting in the late 1990's it has developed into an important herbal medicine in China and is now cultivated there widely, too. AIM OF STUDY: This study aims to provide an insight into the emergence of maca on the global market as an alternative remedy to treat reproductive health related problems in both men and women and to critically assess these health claims...
August 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28807164/effect-of-chinese-herbal-medicine-on-male-infertility
#4
Dan Jiang, Alberto Coscione, Lily Li, Bai-Yun Zeng
Male infertility normally refers a male's inability to cause pregnancy in a fertile female partner after 1 year of unprotected intercourse. Male infertility in recent years has been attracting increasing interest from public due to the evidence in decline in semen quality. There are many factors contributing to the male infertility including abnormal spermatogenesis; reproductive tract anomalies or obstruction; inadequate sexual and ejaculatory functions; and impaired sperm motility, imbalance in hormone levels, and immune system dysfunction...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28807160/treatment-of-chinese-herbal-medicine-for-female-infertility
#5
Dan Jiang, Lily Li, Bai-Yun Zeng
Female infertility is when a woman of reproductive age and sexual active, without contraception, cannot get pregnant after a year and more or keeps having miscarriages. Although conventional treatments for infertility such as hormone therapy, in vitro fertilization and many more, helped many female patients with infertility get pregnant during past a few decades, it is far from satisfactory with prolonging treatment time frames and emotional and financial burden. In recent years, more patients with infertile problems are seeking to alternative and complementary medicines to achieve a better outcome...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28803364/volatile-terpenoids-multiple-functions-biosynthesis-modulation-and-manipulation-by-genetic-engineering
#6
REVIEW
Farhat Abbas, Yanguo Ke, Rangcai Yu, Yuechong Yue, Sikandar Amanullah, Muhammad Muzammil Jahangir, Yanping Fan
Terpenoids play several physiological and ecological functions in plant life through direct and indirect plant defenses and also in human society because of their enormous applications in the pharmaceutical, food and cosmetics industries. Through the aid of genetic engineering its role can by magnified to broad spectrum by improving genetic ability of crop plants, enhancing the aroma quality of fruits and flowers and the production of pharmaceutical terpenoids contents in medicinal plants. Terpenoids are structurally diverse and the most abundant plant secondary metabolites, playing an important role in plant life through direct and indirect plant defenses, by attracting pollinators and through different interactions between the plants and their environment...
August 12, 2017: Planta
https://www.readbyqxmd.com/read/28799235/dipeptidyl-peptidase-4-serum-activity-and-concentration-are-increased-in-women-with-polycystic-ovary-syndrome
#7
Sindy Blauschmidt, Thomas Greither, Katharina Lampe, Solveig Köller, Petra Kaltwaßer, Hermann M Behre
OBJECTIVE: Polycystic ovary syndrome (PCOS) is a complex disease, the etiology of which is not well understood. Alterations in potential candidate genes involved in the biosynthesis and metabolism of androgens, folliculogenesis, and insulin and glucose metabolism have been suggested as possible etiologies. Dipeptidyl peptidase-4 (DPP4) plays a key role in glucose homeostasis and, thus, in the regulation of insulin secretion. The aim of our study was to analyze the DPP4 activity and concentrations in the serum of PCOS and non-PCOS patients and, additionally, study the activation of the DPP4 promoter by androgens in vitro...
August 11, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28792412/evolutionary-public-health-introducing-the-concept
#8
REVIEW
Jonathan C K Wells, Randolph M Nesse, Rebecca Sear, Rufus A Johnstone, Stephen C Stearns
The emerging discipline of evolutionary medicine is breaking new ground in understanding why people become ill. However, the value of evolutionary analyses of human physiology and behaviour is only beginning to be recognised in the field of public health. Core principles come from life history theory, which analyses the allocation of finite amounts of energy between four competing functions-maintenance, growth, reproduction, and defence. A central tenet of evolutionary theory is that organisms are selected to allocate energy and time to maximise reproductive success, rather than health or longevity...
July 29, 2017: Lancet
https://www.readbyqxmd.com/read/28791461/expression-of-h19-imprinted-gene-in-patients-with-repeated-implantation-failure-during-the-window-of-implantation
#9
Hong Zeng, Xiuli Fan, Nenghui Liu
PURPOSE: To detect the expression level of imprinted gene H19 in the endometrium of patients with repeated implantation failure (RIF) who were undergoing in vitro fertilization and embryo transfer (IVF-ET) or frozen embryo transfer (FET). METHODS: Patients who underwent IVF/FET in Reproductive Medicine Center of Xiangya Hospital during April 1, 2015 to October 31, 2015 were chosen. The endometrium was collected from patients with repeated implantation failure during mid-luteal phase...
August 8, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28791440/therapeutic-potentials-of-short-interfering-rnas
#10
REVIEW
Chit Tam, Jack Ho Wong, Randy Chi Fai Cheung, Tao Zuo, Tzi Bun Ng
Short interfering RNA (siRNA) is one of the members of the family of RNA interference (RNAi). Coupled with the RNA-induced silencing complex (RISC), siRNA is able to trigger the cleavage of target RNAs which serve as a defensive system against pathogens. Meanwhile, siRNA in gene silencing opens a new avenue for the treatment of various diseases. SiRNA can effectively inhibit viral infection and replication and suppress tumorigenesis and various inflammation-associated diseases and cardiovascular diseases by inactivation of viral genes and downregulation of oncogene expression...
August 8, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28780659/preconception-counseling-for-women-with-cardiac-disease
#11
REVIEW
Mark A Clapp, Sarah N Bernstein
All providers who care for reproductive-aged women with cardiac disease should assess these patients' desires and plans for pregnancy at every encounter. For those considering pregnancy, preconception counseling, often performed by a maternal-fetal medicine specialist, can help patients understand the potential implications of pregnancy on their health and estimate the risks of an adverse cardiac event prior to conceiving. There are cardiac conditions, such as pulmonary hypertension and aortic stenosis, in which pregnancy may be contraindicated given the high morbidity and mortality; there are tools available to help quantify a patient's risk...
September 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28777929/human-germline-genome-editing
#12
REVIEW
Kelly E Ormond, Douglas P Mortlock, Derek T Scholes, Yvonne Bombard, Lawrence C Brody, W Andrew Faucett, Nanibaa' A Garrison, Laura Hercher, Rosario Isasi, Anna Middleton, Kiran Musunuru, Daniel Shriner, Alice Virani, Caroline E Young
With CRISPR/Cas9 and other genome-editing technologies, successful somatic and germline genome editing are becoming feasible. To respond, an American Society of Human Genetics (ASHG) workgroup developed this position statement, which was approved by the ASHG Board in March 2017. The workgroup included representatives from the UK Association of Genetic Nurses and Counsellors, Canadian Association of Genetic Counsellors, International Genetic Epidemiology Society, and US National Society of Genetic Counselors...
August 3, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28777294/common-genetic-variants-alter-metabolism-and-influence-dietary-choline-requirements
#13
REVIEW
Ariel B Ganz, Kevin C Klatt, Marie A Caudill
Nutrient needs, including those of the essential nutrient choline, are a population wide distribution. Adequate Intake (AI) recommendations for dietary choline (put forth by the National Academies of Medicine to aid individuals and groups in dietary assessment and planning) are grouped to account for the recognized unique needs associated with age, biological sex, and reproductive status (i.e., pregnancy or lactation). Established and emerging evidence supports the notion that common genetic variants are additional factors that substantially influence nutrient requirements...
August 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28777193/endometriosis-in-adolescents
#14
Tazim Dowlut-McElroy, Julie L Strickland
PURPOSE OF REVIEW: The current article addresses recent literature regarding the diagnosis and management of endometriosis in adolescents. RECENT FINDINGS: An increasing body of literature suggests that advanced-stage endometriosis (revised scoring system of the American Society for Reproductive Medicine Stage III or IV) and deeply invasive endometriosis are relatively common in adolescents. There remains limited data on the efficacy of postoperative hormonal management of endometriosis in the adolescent population...
August 1, 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28772093/metabolic-state-can-define-the-ovarian-response-to-environmental-contaminants-and-medicinal-plants
#15
Alexander V Sirotkin, Dušan Fabian, Janka Babeľová Kubandová, Radoslava Vlčková, Saleh Alwasel, Abdel Halim Harrath
Environmental contaminants and medicinal plants can affect reproductive processes. The aim of this study was to investigate the effect of maternal metabolic status on the response of mouse ovaries to the environmental contaminants benzene and xylene, as well as to extracts of the medicinal yucca plant. Ovaries isolated from normal-lean and slightly obese mice were cultured with or without 0.1% benzene or xylene for 24 h. Similarly, ovaries isolated from normal-lean, slightly obese, and significantly obese mice were cultured for 24 h with or without an extract of Yucca shildegera (YS, 10 µg/mL)...
August 3, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28770218/grand-challenge-animal-reproduction-theriogenology-from-the-bench-to-application-to-animal-production-and-reproductive-medicine
#16
EDITORIAL
Ahmed Tibary
No abstract text is available yet for this article.
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28768534/the-use-of-traditional-medicine-in-maternity-care-among-african-women-in-africa-and-the-diaspora-a-systematic-review
#17
Zewdneh Shewamene, Tinashe Dune, Caroline A Smith
BACKGROUND: There is a paucity of literature describing traditional health practices and beliefs of African women. The purpose of this study was to undertake a systematic review of the use of traditional medicine (TM) to address maternal and reproductive health complaints and wellbeing by African women in Africa and the diaspora. METHOD: A literature search of published articles, grey literature and unpublished studies was conducted using eight medical and social science databases (CINAHL, EMBASE, Infomit, Ovid Medline, ProQuest, PsychINFO, PubMed and SCOPUS) from the inception of each database until 31 December 2016...
August 2, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28762666/developmental-toxicity-evaluation-of-pimenta-pseudocaryophyllus-gomes-landrum-e-methyl-isoeugenol-chemotype-in-wistar-rats
#18
Bruce Soares Cardoso, Katia Borges Machado, José Realino de Paula, Joelma Abadia Marciano de Paula, Wilson de Melo Cuvinel, Vanessa Cristiane Santana Amaral
BACKGROUND: Pimenta pseudocaryophyllus (Gomes) Landrum (Myrtaceae) has been traditionally used in Brazilian folk medicine. Studies have established the botanical characterization, phytochemistry profile, and pharmacological potential of this species, including antibiotic, anxiolytic, antidepressant, antioxidant, antinociceptive, and anti-inflammatory properties. Despite its widespread use, no previous study has been conducted regarding its toxicological profile, especially during pregnancy...
August 1, 2017: Birth defects research
https://www.readbyqxmd.com/read/28760517/the-international-glossary-on-infertility-and-fertility-care-2017
#19
Fernando Zegers-Hochschild, G David Adamson, Silke Dyer, Catherine Racowsky, Jacques de Mouzon, Rebecca Sokol, Laura Rienzi, Arne Sunde, Lone Schmidt, Ian D Cooke, Joe Leigh Simpson, Sheryl van der Poel
STUDY QUESTION: Can a consensus and evidence-driven set of terms and definitions be generated to be used globally in order to ensure consistency when reporting on infertility issues and fertility care interventions, as well as to harmonize communication among the medical and scientific communities, policy-makers, and lay public including individuals and couples experiencing fertility problems? SUMMARY ANSWER: A set of 283 consensus-based and evidence-driven terminologies used in infertility and fertility care has been generated through an inclusive consensus-based process with multiple stakeholders...
July 28, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28757310/recommendations-for-harmonization-of-data-collection-and-analysis-of-developmental-neurotoxicity-endpoints-in-regulatory-guideline-studies-proceedings-of-workshops-presented-at-society-of-toxicology-and-joint-teratology-society-and-neurobehavioral-teratology
#20
REVIEW
Abby A Li, Larry P Sheets, Kathleen Raffaele, Virginia Moser, Angela Hofstra, Alan Hoberman, Susan L Makris, Robert Garman, Brad Bolon, Wolfgang Kaufmann, Roland Auer, Edmund Lau, Thomas Vidmar, Wayne J Bowers
The potential for developmental neurotoxicity (DNT) of environmental chemicals may be evaluated using specific test guidelines from the US Environmental Protection Agency or the Organisation for Economic Cooperation and Development (OECD). These guidelines generate neurobehavioral, neuropathological, and morphometric data that are evaluated by regulatory agencies globally. Data from these DNT guideline studies, or the more recent OECD extended one-generation reproductive toxicity guideline, play a pivotal role in children's health risk assessment in different world areas...
July 27, 2017: Neurotoxicology and Teratology
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