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https://www.readbyqxmd.com/read/28733191/ethnomedicobotanical-study-of-indigenous-knowledge-on-medicinal-plants-used-for-the-treatment-of-reproductive-problems-in-nalbari-district-assam-india
#1
Simi Talukdar, Partha Pradip Adhikari, Ananta Borah
ETHNOPHARMACOLOGICAL RELEVANCE: Reproductive problems are evolving as most predominant health care problems in many countries, furthermore, WHO, 2012 exemplified maternal illnesses, birth asphyxia and post birth difficulties, are rising at an alarming rate.Not all abnormalities of the human reproductive system have the same origin; the effects on reproductive problems would likely be affected by both male and female. For easy accessibility and affordability medicinal plants play a key role in primary healthcare care services in India and their use is an integral part of the cultural heritage...
July 18, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28732324/anti-m%C3%A3-llerian-hormone-amh-levels-in-premenopausal-breast-cancer-patients-treated-with-taxane-based-adjuvant-chemotherapy-a-translational-research-project-of-the-success-a-study
#2
E K Trapp, J Steidl, B Rack, M S Kupka, U Andergassen, J Jückstock, A Kurt, T Vilsmaier, A de Gregorio, N de Gregorio, M Tzschaschel, C Lato, A Polasik, H Tesch, A Schneeweiss, M W Beckmann, P A Fasching, W Janni, V Müller
BACKGROUND: Premenopausal women undergoing chemotherapy are at high risk for premature ovarian failure and its long-term consequences. Data on potential markers to evaluate ovarian reserve pre- and posttreatment are limited. Anti-Müllerian hormone (AMH) known for ovarian reserve in reproductive medicine could be a surrogate marker and was assessed in premenopausal breast cancer patients of the SUCCESS A study (EUDRA-CT no. 2005-000490-21). METHODS: We identified 170 premenopausal patients, age ≤ 40 years at trial entry, who received FEC-Doc as taxane-anthracylince based chemotherapy...
July 18, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28722201/susceptibility-induced-distortion-correction-in-hyperpolarized-echo-planar-imaging
#3
Jack J Miller, Angus Z Lau, Damian J Tyler
PURPOSE: Echo planar imaging is an attractive rapid imaging readout that can image hyperpolarized compounds in vivo. By alternating the sign of the phase encoding gradient waveform, spatial offsets arising from uncertain frequency shifts can be determined. We show here that blip-reversed echo planar imaging can also be used to correct for susceptibility and B0 inhomogeneity effects that would otherwise produce image-domain distortion in the heart. METHODS: Previously acquired blip-reversed cardiac 3D-Spectral-Spatial echo planar imaging volumetric timecourses of hyperpolarized [1-(13) C]pyruvate were distortion corrected by a deformation field estimated by reconstructing signal-to-noise ratio (SNR)-weighted progressively subsampled temporally summed images of each metabolite...
July 19, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28721186/factors-driving-the-global-decline-of-cycad-diversity
#4
Ledile T Mankga, Kowiyou Yessoufou
Mounting evidence indicates that we are witnessing the sixth mass extinction period. Given the important goods and services biodiversity delivers to humans, there is a need for a continued commitment to investigate what pre-disposes some taxa to greater risk of extinction. Here, we investigate this question using a phylogenetic comparative method and fitting a cumulative link mixed effect model on biological, ecological and evolutionary data of cycads, the most threatened lineage in the plant kingdom. We identified nine groups of threats to cycads, with habitat loss, over-collection, fire and reproduction failure being the most prominent, but only four of these threats (habitat loss, over-collection, medicinal uses and reproduction failure) clustered on the cycad tree of life...
July 2017: AoB Plants
https://www.readbyqxmd.com/read/28711704/detection-of-zikv-rna-in-semen-of-asymptomatic-blood-donors
#5
Didier Musso, Vaea Richard, Anita Teissier, Mars Stone, Marion C Lanteri, Geraldo Latoni, Jose Alsina, Rita Reik, Michael P Busch
OBJECTIVES: Zika virus (ZIKV) transmission through semen donation has never been reported but the risk is supported by the detection of ZIKV in semen and the demonstration of ZIKV sexual transmission. The potential impact of ZIKV on assisted reproductive procedures should be evaluated. METHODS: We tested longitudinally collected semen samples provided by asymptomatic blood donors who tested positive for ZIKV RNA in plasma during ZIKV outbreaks in Puerto Rico and Florida in 2016...
July 12, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28709873/deregulation-of-wnt2-fzd3-%C3%AE-catenin-pathway-compromises-the-estrogen-synthesis-in-cumulus-cells-from-patients-with-polycystic-ovary-syndrome
#6
Gu-Yuan Qiao, Bing-Wei Dong, Chao-Juan Zhu, Chang-You Yan, Bi-Liang Chen
Mechanistic insight into estrogen deficiency by polycystic ovary syndrome (PCOS) remains a longstanding challenge in reproductive medicine. Recent advance suggest that Wingless-type MMTV integration site family members (WNTs), in concert with its Frizzled (FZD) receptors, regulate normal folliculogenesis, luteogenesis and ovarian steroidogenesis. However, no studies have so far investigated any causality between WNT-FZDs interactions and disrupted estrogen synthesis under certain pathological conditions. Here, we show that (i) FZD3 expression was significantly up-regulated in the cumulus cells (CCs) from PCOS patients...
July 11, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28706397/assessment-of-sperm-deoxyribose-nucleic-acid-fragmentation-using-sperm-chromatin-dispersion-assay
#7
Harsha Pratap, Suma Yekappa Hottigoudar, Kubera Siddappa Nichanahalli, Parkash Chand
The integrity of sperm deoxyribose nucleic acid (DNA) is one of the determinants that ensure normal fertilization, implantation, pregnancy, and the generation of a healthy progeny. Assessment of sperm DNA fragmentation has gained importance as a tool to provide significant information regarding sperm quality, and it can independently predict sperm fertilizing potential. The sperm chromatin dispersion (SCD) assay is one of the available techniques to detect sperm DNA damage with results comparable to the gold standard - Sperm Chromatin Structure Assay...
April 2017: Journal of Pharmacology & Pharmacotherapeutics
https://www.readbyqxmd.com/read/28701210/follicular-fluid-redox-involvement-for-ovarian-follicle-growth
#8
REVIEW
Cláudia Freitas, Ana Catarina Neto, Liliana Matos, Elisabete Silva, Ângela Ribeiro, João Luís Silva-Carvalho, Henrique Almeida
As the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cells and the follicular fluid (FF).In contrast to the dynamic nature of cells, the fluid compartment appears as a reservoir rich in biomolecules. In some aspects, it is similar to the plasma, but it also exhibits differences that likely relate to its specific localization around the oocyte. The chemical composition indicates that the follicular fluid is able to detect and buffer excessive amounts of reactive oxygen species, employing a variety of antioxidants, some of them components of the intracellular milieu...
July 12, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28701045/investigating-chemical-composition-and-indications-of-hydrosol-soft-drinks-aromatic-waters-used-in-persian-folk-medicine-for-women-s-hormonal-and-reproductive-health-conditions
#9
Azadeh Hamedi, Mehdi Afifi, Hamed Etemadfard
Hydrosol soft drinks in Persian nutrition culture are produced as side products of the essential oil industry to be used as safe remedies for treatment of some ailments. This study investigated hydrosols for women's hormonal health conditions. Detailed information was gathered by questionnaires. Chemical constituents of these mono- or poly-herbal hydrosols were identified after liquid/liquid extraction and gas chromatography-mass spectrometry. Hierarchical cluster and K-means analysis (SPSS software) were used to find their relevance...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28699211/better-and-faster-velocity-pulsatility-assessment-in-cerebral-white-matter-perforating-arteries-with-7t-quantitative-flow-mri-through-improved-slice-profile-acquisition-scheme-and-postprocessing
#10
Lennart Geurts, Geert Jan Biessels, Peter Luijten, Jaco Zwanenburg
PURPOSE: A previously published cardiac-gated 2D Qflow protocol at 7 T in cerebral perforating arteries was optimized to reduce velocity underestimation and improve temporal resolution. METHODS: First, the signal-to-noise ratio (SNR) gain of the velocity measurement (SNRv ) was tested for two signal averages versus one. Second, the decrease in velocity underestimation with a tilted optimized nonsaturating excitation (TONE) pulse was tested. Third, the decrease in pulsatility index (PI) underestimation through improved temporal resolution was tested...
July 11, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28697916/treatments-for-opioid-use-disorder-among-pregnant-and-reproductive-aged-women
#11
REVIEW
Dennis J Hand, Vanessa L Short, Diane J Abatemarco
The increased prevalence of opioid use disorder and access to medical insurance is subsequently increasing the likelihood that medical professionals will encounter individuals with opioid use disorder. Sharp increases in opioid use disorder among women mean that obstetricians, gynecologists, and other reproductive medicine providers may be especially likely to encounter such patients. Medical professionals' understanding of treatment for opioid use disorder and their roles in their patients' treatment may increase referrals to treatment, reduce stigma, and improve the quality of medical care...
July 8, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28697914/introduction-the-specter-of-opiate-addiction-in-reproductive-medicine
#12
William D Schlaff
The alarming trend in opiate misuse in developed countries is prompting an increasingly strident public call for action. Although many in our field have assumed that this building crisis does not really affect us or our patients, data show that the emerging demographic at highest risk for misusing opiates clearly includes patients who seek care in our practices. The goals of this Views and Reviews are to provide a clear understanding of emerging trends in opiate misuse, to review the impact of opiates on the reproductive axis, and to suggest practical recommendations aimed at both mitigating iatrogenic influences on promoting misuse and developing treatment frameworks when misuse is suspected or identified...
July 8, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28697118/finding-middle-ground-in-constructing-a-clinically-useful-expanded-carrier-screening-panel
#13
Blair Stevens, Nevena Krstic, Malorie Jones, Lauren Murphy, Jennifer Hoskovec
Expanded carrier screening for autosomal-recessive conditions effectively identifies more carrier couples than traditional guideline-based carrier screening. However, clinically available expanded carrier screening panels include numerous conditions, some of which have questionable clinical utility as a result of very low carrier frequency, low or unknown testing sensitivity, and mild or incompletely penetrant phenotypes. Using the 2013 American College of Medical Genetics and Genomics Position Statement on Prenatal and Preconception Expanded Carrier Screening and the 2017 American College of Obstetricians and Gynecologists' Committee Opinion on Carrier Screening in the Age of Genomic Medicine as guidance, we propose specific criteria for the development of expanded carrier screening panels that will maximize clinical utility and minimize patient stress, unnecessary cost of follow-up testing, and clinician time spent facilitating and performing follow-up counseling and testing...
July 7, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28695774/regulatory-risk-assessments-is-there-a-need-to-reduce-uncertainty-and-enhance-robustness-update-on-propylparaben-in-relation-to-its-eu-regulatory-status
#14
D Snodin
Over 10 years ago, propylparaben (propyl- p-hydroxybenzoate; PP) was withdrawn as a permitted food preservative in the EU based entirely on findings reported in a single dietary study in juvenile rats claiming to show adverse effects on male reproductive parameters [Oishi S. Effects of propyl paraben on the male reproductive system. Food Chem Toxicol 2002; 40(12): 1807 -1813]. Subsequent data reviews have cast serious doubt on the validity of the Oishi results, mainly in relation to aberrant concurrent-control values, and in two further comprehensive studies using neonatal and juvenile rats there were no adverse effects in males at oral doses up to 1000 mg/kg/day...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28692354/potential-protective-effects-of-polysaccharide-extracted-from-ulva-lactuca-against-male-reprotoxicity-induced-by-thiacloprid
#15
Intissar Kammoun, Intidhar Bkhairia, Fatma Ben Abdallah, Imen Jaballi, Naourez Ktari, Ons Boudawara, Moncef Nasri, Neji Gharsallah, Ahmed Hakim, Ibtissem Ben Amara
CONTEXT: Polysaccharides (PSs) from seaweeds have been reported to possess biological activity of potential medicinal values. OBJECTIVE: The current study was conducted to establish the protective effects of PS extracted from Ulva lactuca against oxidative stress induced by Thiacloprid (THC) in the rat reproductive system. MATERIALS AND METHODS: Rats were exposed either to THC, THC + PS (100 mg/kg), or THC + PS (200 mg/kg). RESULTS: Our study showed that THC induced severe disorders in the functional sperm parameters...
July 10, 2017: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28691729/in-vitro-differentiation-of-primordial-germ-cells-and-oocyte-like-cells-from-stem-cells
#16
REVIEW
José J N Costa, Glaucinete B Souza, Maria A A Soares, Regislane P Ribeiro, Robert van den Hurk, José R V Silva
Infertility is the result of failure due to an organic disorder of the reproductive organs, especially their gametes. Recently, much progress has been made on generating germ cells, including oocytes, from various types of stem cells. This review focuses on advances in female germ cell differentiation from different kinds of stem cells, with emphasis on embryonic stem cells, adult stem cells, and induced pluripotent stem cells. The advantages and disadvantages of the derivation of female germ cells from several types of stem cells are also highlighted, as well as the ability of stem cells to generate mature and functional female gametes...
July 10, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/28686785/liquid-crystal-phantom-for-validation-of-microscopic-diffusion-anisotropy-measurements-on-clinical-mri-systems
#17
Markus Nilsson, Johan Larsson, Dan Lundberg, Filip Szczepankiewicz, Thomas Witzel, Carl-Fredrik Westin, Karin Bryskhe, Daniel Topgaard
PURPOSE: To develop a phantom for validating MRI pulse sequences and data processing methods to quantify microscopic diffusion anisotropy in the human brain. METHODS: Using a liquid crystal consisting of water, detergent, and hydrocarbon, we designed a 0.5-L spherical phantom showing the theoretically highest possible degree of microscopic anisotropy. Data were acquired on the Connectome scanner using echo-planar imaging signal readout and diffusion encoding with axisymmetric b-tensors of varying magnitude, anisotropy, and orientation...
July 7, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28685911/combined-lifestyle-and-herbal-medicine-in-overweight-women-with-polycystic-ovary-syndrome-pcos-a-randomized-controlled-trial
#18
Susan Arentz, Caroline A Smith, Jason Abbott, Paul Fahey, Birinder S Cheema, Alan Bensoussan
Polycystic ovary syndrome (PCOS) is a common, complex reproductive endocrinopathy characterized by menstrual irregularities, hyperandrogenism and polycystic ovaries. Lifestyle modification is a first-line intervention; however, there are barriers to success for this form of self-care, and women often seek adjunct therapies including herbal medicines. This pragmatic, randomized controlled trial, delivered in communities of Australia in overweight women with PCOS, compared the effectiveness and safety of a lifestyle intervention plus herbal medicine against lifestyle alone...
July 7, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28681949/age-stratified-thresholds-of-anti-m%C3%A3-llerian-hormone-improve-prediction-of-polycystic-ovary-syndrome-over-a-population-based-threshold
#19
Molly M Quinn, Chia-Ning Kao, Asima K Ahmad, Daniel J Haisenleder, Nanette Santoro, Esther Eisenberg, Richard S Legro, Marcelle I Cedars, Heather G Huddleston
OBJECTIVE: Due to its consistent elevation in polycystic ovary syndrome (PCOS) and correlation with polycystic ovarian morphology (PCOM), anti-Mullerian hormone (AMH) has been proposed as a marker of the syndrome. However, prior studies reporting thresholds of AMH for a PCOS diagnosis have been limited by small sample size, inappropriate controls, and heterogeneous AMH assays. We sought to evaluate the suitability of a standardized AMH assay as a biomarker of PCOS. DESIGN: Cross-sectional study at academic medical centers across the United States...
July 6, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28668647/toxicological-evaluation-of-the-aqueous-whole-plant-extract-of-aerva-lanata-l-juss-ex-schult-amaranthaceae
#20
Kayode S Omotoso, Flora R Aigbe, Olanrewaju A Salako, Micah C Chijioke, Oluwafunmilayo O Adeyemi
ETHNOPHARMACOLOGICAL RELEVANCE: Aerva lanata (L.) of the family Amaranthaceae is a Nigerian medicinal plant used traditionally for the management of lithiasis, headache, renal disorder, haematemesis, bronchitis, nasal bleeding, cough, scorpion stings, fractures and spermatorrhoea. Studies that show the pharmacological basis for some of such uses have been reported. There is, however, no scientific report on its toxicity profile to the best of our knowledge. AIM OF THE STUDY: This study was therefore aimed at investigating the toxicity profile of the aqueous extract of Aerva lanata...
June 28, 2017: Journal of Ethnopharmacology
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