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https://www.readbyqxmd.com/read/28103873/masquelier-s-grape-seed-extract-from-basic-flavonoid-research-to-a-well-characterized-food-supplement-with-health-benefits
#1
REVIEW
Antje R Weseler, Aalt Bast
Careful characterization and standardization of the composition of plant-derived food supplements is essential to establish a cause-effect relationship between the intake of that product and its health effect. In this review we follow a specific grape seed extract containing monomeric and oligomeric flavan-3-ols from its creation by Jack Masquelier in 1947 towards a botanical remedy and nutraceutical with proven health benefits. The preparation's research history parallels the advancing insights in the fields of molecular biology, medicine, plant and nutritional sciences during the last 70 years...
January 19, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28103799/comparative-rna-seq-based-transcriptomic-analysis-of-bud-dormancy-in-grape
#2
Muhammad Khalil-Ur-Rehman, Long Sun, Chun-Xia Li, Muhammad Faheem, Wu Wang, Jian-Min Tao
BACKGROUND: Bud dormancy is an important biological phenomenon of perennial plants that enables them to survive under harsh environmental circumstances. Grape (Vitis vinifera) is one of the most grown fruit crop worldwide; however, underlying mechanisms involved in grape bud dormancy are not yet clear. This work was aimed to explore the underlying molecular mechanism regulating bud dormancy in grape. RESULTS: We have performed transcriptome and differential transcript expression analyses of "Shine Muscat" grape buds using the Illumina RNA-seq system...
January 19, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28103406/evaluation-of-the-ability-of-polyphenol-extracts-of-cocoa-and-red-grape-to-promote-the-antioxidant-response-in-yeast-using-a-rapid-multiwell-assay
#3
Ana Peláez-Soto, María Teresa Fernández-Espinar, Patricia Roig, José Vicente Gil
Saccharomyces cerevisiae has been used as a model organism to study the capacity of cocoa and red grape extracts to trigger an antioxidant response. A methodology adapted to microtiter plates has been developed to monitor yeast growth after culture preincubation with food ingredients and exposure to oxidative stress by hydrogen peroxide and menadione. This methodology proved effective in measuring the ability of cocoa and red grape extracts to promote an antioxidant response in yeast, and also the prospect of conducting dose-response studies...
January 19, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28101667/impact-of-an-arbuscular-mycorrhizal-fungus-versus-a-mixed-microbial-inoculum-on-the-transcriptome-reprogramming-of-grapevine-roots
#4
Raffaella Balestrini, Alessandra Salvioli, Alessandra Dal Molin, Mara Novero, Giovanni Gabelli, Eleonora Paparelli, Fabio Marroni, Paola Bonfante
Grapevine, cultivated for both fruit and beverage production, represents one of the most economically important fruit crops worldwide. With the aim of better understanding how grape roots respond to beneficial microbes, a transcriptome sequencing experiment has been performed to evaluate the impact of a single arbuscular mycorrhizal (AM) fungal species (Funneliformis mosseae) versus a mixed inoculum containing a bacterial and fungal consortium, including different AM species, on Richter 110 rootstock. Results showed that the impact of a single AM fungus and of a complex microbial inoculum on the grapevine transcriptome differed...
December 27, 2016: Mycorrhiza
https://www.readbyqxmd.com/read/28100511/higher-dietary-flavonoid-intakes-are-associated-with-lower-objectively-measured-body-composition-in-women-evidence-from-discordant-monozygotic-twins
#5
Amy Jennings, Alex MacGregor, Tim Spector, Aedín Cassidy
BACKGROUND: Although dietary flavonoid intake has been associated with less weight gain, there are limited data on its impact on fat mass, and to our knowledge, the contribution of genetic factors to this relation has not previously been assessed. OBJECTIVE: We examined the associations between flavonoid intakes and fat mass. DESIGN: In a study of 2734 healthy, female twins aged 18-83 y from the TwinsUK registry, intakes of total flavonoids and 7 subclasses (flavanones, anthocyanins, flavan-3-ols, flavonols, flavones, polymers, and proanthocyanidins) were calculated with the use of food-frequency questionnaires...
January 18, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28098345/effect-of-sequential-fermentations-and-grape-cultivars-on-volatile-compounds-and-sensory-profiles-of-danish-wines
#6
Jing Liu, Nils Arneborg, Torben B Toldam-Andersen, Mikael A Petersen, Wender L P Bredie
BACKGROUND: There has been increasing interest in the use of selected non-Saccharomyces yeasts in co-culture with Saccharomyces cerevisiae. In this work, three non-Saccharomyces yeast strains (Metschnikowia viticola, Metschnikowia fructicola and Hanseniaspora uvarum) indigenously isolated in Denmark, were used in sequential fermentations with S. cerevisiae on three cool-climate grape cultivars Bolero, Rondo and Regent. During the fermentations, the yeast growth was determined as well as key oenological parameters, volatile compounds and sensory properties of finished rosé wines...
January 18, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28098337/characterisation-of-the-enzymatic-properties-of-mpapr1-an-aspartic-protease-secreted-by-the-wine-yeast-metschnikowia-pulcherrima
#7
Louwrens Wiid Theron, Marina Bely, Benoit Divol
BACKGROUND: MpAPr1, encoding an acid protease from the wine yeast Metschnikowia pulcherrima IWBT Y1123, was previously isolated and shown to display potential activity against casein and grape proteins. However, its characterisation remained partial. RESULTS: MpAPr1 was cloned into the pGAPZαA vector and transformed into Komagataella pastoris X33 for heterologous expression. After verification of activity, the enzyme properties were characterised. Protease activity within the concentrated supernatant was retained over a pH range of 3...
January 18, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28094544/red-wine-and-pomegranate-extracts-suppress-cured-meat-promotion-of-colonic-mucin-depleted-foci-in-carcinogen-induced-rats
#8
Nadia M Bastide, Nathalie Naud, Gilles Nassy, Jean-Luc Vendeuvre, Sylviane Taché, Françoise Guéraud, Ditte A Hobbs, Gunter G Kuhnle, Denis E Corpet, Fabrice H F Pierre
Processed meat intake is carcinogenic to humans. We have shown that intake of a workshop-made cured meat with erythorbate promotes colon carcinogenesis in rats. We speculated that polyphenols could inhibit this effect by limitation of endogenous lipid peroxidation and nitrosation. Polyphenol-rich plant extracts were added to the workshop-made cured meat and given for 14 days to rats and 100 days to azoxymethane-induced rats to evaluate the inhibition of preneoplastic lesions. Colons of 100-d study were scored for precancerous lesions (mucin-depleted foci, MDF), and biochemical end points of peroxidation and nitrosation were measured in urinary and fecal samples...
January 17, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28094155/sustainable-options-for-the-utilization-of-solid-residues-from-wine-production
#9
Nansen Zhang, Andrew Hoadley, Jim Patel, Seng Lim, Chao'en Li
The efficient use of solid organic waste materials is an issue of particular importance for the wine industry. This paper focuses on the valorization of grape marc, the major component of winery organic waste (60-70%). Two methods were designed and compared: combustion to generate electricity, and the pyrolysis for the production of bio-char, bio-oil, and bio-gas. Each of these processes was analysed to determine their economic and environmental viability. The flow-sheeting software, ASPEN PLUS, was used to model the two cases...
January 13, 2017: Waste Management
https://www.readbyqxmd.com/read/28091574/an-inert-pesticide-adjuvant-synergizes-viral-pathogenicity-and-mortality-in-honey-bee-larvae
#10
Julia D Fine, Diana L Cox-Foster, Christopher A Mullin
Honey bees are highly valued for their pollination services in agricultural settings, and recent declines in managed populations have caused concern. Colony losses following a major pollination event in the United States, almond pollination, have been characterized by brood mortality with specific symptoms, followed by eventual colony loss weeks later. In this study, we demonstrate that these symptoms can be produced by chronically exposing brood to both an organosilicone surfactant adjuvant (OSS) commonly used on many agricultural crops including wine grapes, tree nuts and tree fruits and exogenous viral pathogens by simulating a horizontal transmission event...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28081154/sensitization-of-radioresistant-prostate-cancer-cells-by-resveratrol-isolated-from-arachis-hypogaea-stems
#11
Yu-An Chen, Hsiu-Man Lien, Min-Chuan Kao, U-Ging Lo, Li-Chiung Lin, Chun-Jung Lin, Sheau-Jiun Chang, Chia-Chang Chen, Jer-Tsong Hsieh, Ho Lin, Chih-Hsin Tang, Chih-Ho Lai
Resveratrol (RV, 3,4',5-trihydroxystilbene) is naturally produced by a wide variety of plants including grapes and peanuts (Arachis hypogaea). However, the yield of RV from peanut stem and its potential radiosensitizing effects in prostate cancer (PCa) have not been well investigated. In this study, we characterized RV in peanut stem extract (PSE) for the first time and showed that both RV and PSE dose-dependently induced cell death in DOC-2/DAB2 interactive protein (DAB2IP)-deficient PCa cells with the radioresistant phenotype...
2017: PloS One
https://www.readbyqxmd.com/read/28079008/walking-a-tightrope-a-perspective-of-resveratrol-effects-on-breast-cancer
#12
Caterina Bartolacci, Cristina Andreani, Augusto Amici, Cristina Marchini
It is an acknowledged fact that health benefits are derived from fruit- and vegetables-enriched diets. In particular, polyphenols, compounds bearing one or more hydroxyl groups attached to an aromatic ring, are ascribed for most of such beneficial effects. Among them, resveratrol, a phytoalexin found in numerous plant species, and more notably in grapes, has widely piqued the interest of the scientific community by virtue of its anti-aging, anti-inflammatory and anti-oxidant properties. Moreover, evidence claiming resveratrol ability to hinder processes underlying all the three steps of carcinogenesis (tumor initiation, progression and metastasization) has propelled an incredibly massive number of studies aimed at enquiring its eventual clinical potential in the fight against cancer...
January 11, 2017: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/28076832/dietary-supplementation-of-grape-seed-and-skin-flour-mitigates-brain-oxidative-damage-induced-by-a-high-fat-diet-in-rat-gender-dependency
#13
Kamel Charradi, Mohamed Mahmoudi, Takwa Bedhiafi, Safwen Kadri, Salem Elkahoui, Ferid Limam, Ezzedine Aouani
It is unknown whether gender has an impact on brain injury in obesity, and, if so, whether treatment with grape seed and skin flour could exert a protective effect. Both male and female rats were fed a standard diet (SD) or a high fat diet (HFD) during eight weeks and treated with high dosage grape seed and skin flour (GSSF). Fat-induced oxidative stress was evaluated into the brain with a special emphasis on transition metals determination. HFD induced male-cholesterol overload (+78.12%) and an oxidative stress status characterized by increased lipoperoxidation (+68...
January 8, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28074795/comparative-effect-of-grape-seed-extract-vitis-vinifera-and-ascorbic-acid-in-oxidative-stress-induced-by-on-pump-coronary-artery-bypass-surgery
#14
Naser Safaei, Hossein Babaei, Rasoul Azarfarin, Ahmad-Reza Jodati, Alireza Yaghoubi, Mohammad-Ali Sheikhalizadeh
BACKGROUND: This study aimed to test the beneficial effect of grape seed extract (GSE) (Vitis vinifera) and Vitamin C in oxidative stress and reperfusion injury induced by cardiopulmonary bypass (CPB) in coronary artery bypass surgery. PATIENTS AND METHODS: In this randomized trial, 87 patients undergoing elective and isolated coronary bypass surgery included. The patients were randomly assigned into three groups (n = 29 each): (1) Control group with no treatment, (2) GSE group who received the extract 24 h before operation, 100 mg every 6 h, orally, (3) Vitamin C group who received 25 mg/kg Vitamin C through CPB during surgery...
January 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28068488/side-streams-of-plant-food-processing-as-a-source-of-valuable-compounds-selected-examples
#15
Andreas Schieber
Industrial processing of plant-derived raw materials generates enormous amounts of by-products. On one hand, these by-products constitute a serious disposal issue because they often emerge seasonally and are prone to microbial decay. On the other hand, they are an abundant source of valuable compounds, in particular secondary plant metabolites and cell wall materials, which may be recovered and used to functionalize foods and replace synthetic additives with ingredients of natural origin. This review covers 150 references and presents select studies performed between 2001 and 2016 on the recovery, characterization, and application of valuable constituents from grape pomace, apple pomace, potato peels, tomato pomace, carrot pomace, onion peels, by-products of citrus, mango, banana, and pineapple processing, side streams of olive oil production, and cereal by-products...
January 4, 2017: Annual Review of Food Science and Technology
https://www.readbyqxmd.com/read/28067267/polydatin-protects-the-respiratory-system-from-pm2-5-exposure
#16
Xiao-Dan Yan, Qi-Ming Wang, Cai Tie, Hong-Tao Jin, Yan-Xing Han, Jin-Lan Zhang, Xiao-Ming Yu, Qi Hou, Piao-Piao Zhang, Ai-Ping Wang, Pei-Cheng Zhang, Zhonggao Gao, Jian-Dong Jiang
Atmospheric particle is one of the risk factors for respiratory disease; however, their injury mechanisms are poorly understood, and prevention methods are highly desirable. We constructed artificial PM2.5 (aPM2.5) particles according to the size and composition of actual PM2.5 collected in Beijing. Using these artificial particles, we created an inhalation-injury animal model. These aPM2.5 particles simulate the physical and chemical characteristics of the actual PM2.5, and inhalation of the aPM2.5 in rat results in a time-dependent change in lung suggesting a declined lung function, injury from oxidative stress and inflammation in lung...
January 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28064492/influence-of-winemaking-processing-steps-on-the-amounts-of-e-2-decenal-and-tridecane-as-off-odorants-caused-by-brown-marmorated-stink-bug-halyomorpha-halys
#17
Pallavi Mohekar, James Osborne, Nik G Wiman, Vaughn Walton, Elizabeth Tomasino
Brown marmorated stink bugs (BMSB) release stress compounds, tridecane and (E)-2-decenal, that effect final wine quality. This study focuses on determining the effect of wine processing on (E)-2-decenal and tridecane release in both red and white wines. Wines were produced by adding live BMSB to grape clusters at densities of 0, 0.3, 1 and 3 bugs per cluster. Compound concentrations were measured using HS-SPME-MDGC-MS. For red wines, the highest levels of stress compounds were found using 3 BMSB/cluster (tridecane, 614 µg/L and (E)-2-decenal, 2...
January 8, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28064119/identification-and-expression-analysis-of-the-nac-transcription-factor-family-in-durum-wheat-triticum-turgidum-l-ssp-durum
#18
Mohammed Najib Saidi, Dhawya Mergby, Faiçal Brini
The NAC (NAM, ATAF and CUC) proteins belong to one of the largest plant-specific transcription factor (TF) families and play important roles in plant development processes, response to biotic and abiotic cues and hormone signaling. Our analysis led to the identification of 168 NAC genes in durum wheat, including nine putative membrane-bound TFs and 48 homeologous genes pairs. Phylogenetic analyses of TtNACs along with their Arabidopsis, grape, barley and rice counterparts divided these proteins into 8 phylogenetic groups and allowed the identification of TtNAC-A7, TtNAC-B35, TtNAC-A68, TtNAC-B69 and TtNAC-A43 as homologs of OsNAC1, OsNAC8, OsNTL2, OsNTL5 and ANAC025/NTL14, respectively...
January 2, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28064013/changes-in-liver-proteins-of-rats-fed-standard-and-high-fat-and-sucrose-diets-induced-by-fish-omega-3-pufas-and-their-combination-with-grape-polyphenols-according-to-quantitative-proteomics
#19
Lucía Méndez, Sergio Ciordia, María Soledad Fernández, Silvia Juárez, Antonio Ramos, Manuel Pazos, José M Gallardo, Josep Lluís Torres, M Rosa Nogués, Isabel Medina
This study considered the physiological modulation of liver proteins due to the supplementation with fish oils under two dietary backgrounds: standard or high in fat and sucrose (HFHS), and their combination with grape polyphenols. By using a quantitative proteomics approach, we showed that the capacity of the supplements for regulating proteins depended on the diet; namely, 10 different proteins changed into standard diets, while 45 changed into the HFHS diets and only scarcely proteins were found altered in common...
December 21, 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28060498/1-8-cineole-in-french-red-wines-evidence-for-a-contribution-related-to-its-various-origins
#20
Xavier Poitou, Cécile Thibon, Philippe Darriet
The aromatic descriptor "green", reflecting grape unripeness in French red wines, is frequently associated with the levels of 3-alkyl-2-methoxypyrazines, particularly 3-isobutyl-2-methoxypyrazine (IBMP), which has bell pepper nuances. Nevertheless, not all green aromatic expressions in red wines correlate with 3-alkyl-2-methoxypyrazine concentrations. This study considered sensory and chemical approaches using Cabernet Sauvignon wines obtained from grapes harvested at one-month intervals during the 2014 and 2015 vintages to investigate other volatile odoriferous compounds...
January 18, 2017: Journal of Agricultural and Food Chemistry
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