Hendris Wongso, Ahmad Kurniawan, Yanuar Setiadi, Crhisterra E Kusumaningrum, Eva M Widyasari, Teguh H A Wibawa, Isa Mahendra, Muhamad B Febrian, Maula E Sriyani, Iim Halimah, Isti Daruwati, Rudi Gunawan, Arifudin Achmad, Dwianto H Nugraha, Ronny Lesmana, Ari S Nugraha
The translocator protein 18-kDa (TSPO) is a mitochondrial membrane protein that is previously identified as the peripheral benzodiazepine receptor (PBR). Furthermore, it plays a significant role in a diverse range of biochemical processes, including steroidogenesis, mitochondrial cholesterol transport, cell survival and death, cell proliferation, and carcinogenesis. Several investigations also reported its roles in various types of cancers, including colorectal, brain, breast, prostate, and lung cancers, as well as melanoma...
March 2024: Advanced Pharmaceutical Bulletin