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https://www.readbyqxmd.com/read/28688825/three-dimensional-bio-printed-scaffold-sleeves-with-mesenchymal-stem-cells-for-enhancement-of-tendon-to-bone-healing-in-anterior-cruciate-ligament-reconstruction-using-soft-tissue-tendon-graft
#1
Sin Hyung Park, Yeong-Jin Choi, Sang Won Moon, Byung Hoon Lee, Jin-Hyung Shim, Dong-Woo Cho, Joon Ho Wang
PURPOSE: To investigate the efficacy of the insertion of 3-dimensional (3D) bio-printed scaffold sleeves seeded with mesenchymal stem cells (MSCs) to enhance osteointegration between the tendon and tunnel bone in anterior cruciate ligament (ACL) reconstruction in a rabbit model. METHODS: Scaffold sleeves were fabricated by 3D bio-printing. Before ACL reconstruction, MSCs were seeded into the scaffold sleeves. ACL reconstruction with hamstring tendon was performed on both legs of 15 adult rabbits (aged 12 weeks)...
July 5, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28677765/expression-and-antimicrobial-character-of-cells-transfected-with-human-%C3%AE-%C3%A2-defensin%C3%A2-3-against-periodontitis%C3%A2-associated-microbiota-in-vitro
#2
Minwen Zhu, Bo Miao, Jianhua Zhu, Haiyan Wang, Zengtong Zhou
Periodontitis is an oral chronic inflammatory disease induced by microorganisms that can destroy tooth‑supporting structures. Human β‑defensin‑3 (HBD‑3) is a type of endogenous antimicrobial peptide that inhibits a broad spectrum of microorganisms. The objectives of the present study were to transfect human periodontal ligament cells (HPDLCs) and human bone marrow stromal cells (HBMSCs) with lentivirus containing the HBD‑3 gene, determine the transfection efficiency, and investigate the antimicrobial activity of the experimental cells against periodontal pathogens...
July 4, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28618175/the-ominous-association-between-severe-endometriosis-in-vitro-fertilisation-and-placenta-praevia-raising-awareness-limiting-risks-informing-women
#3
Paolo Vercellini, Maria Pina Frattaruolo, Giussy Barbara, Laura Buggio, Edgardo Somigliana
Endometriosis is associated with several adverse pregnancy outcomes.(1) The most severe maternal complications are spontaneous haemoperitoneum in the second half of pregnancy and placenta praevia.(1) Spontaneous haemoperitoneum, mostly associated with endometriosis infiltrating the broad and uterosacral ligaments and the Douglas pouch, is a potentially fatal but rare event. Placenta praevia is more common,(1-3) and it is important to define its incidence, the association with different lesion types, the impact of additional risk factors, the potential obstetrical consequences, and the information that women should receive...
June 15, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28610433/reoperation-rates-after-combined-anterior-cruciate-ligament-and-anterolateral-ligament-reconstruction-a-series-of-548-patients-from-the-santi-study-group-with-a-minimum-follow-up-of-2-years
#4
Mathieu Thaunat, Gilles Clowez, Adnan Saithna, Maxime Cavalier, Eric Choudja, Thais D Vieira, Jean-Marie Fayard, Bertrand Sonnery-Cottet
BACKGROUND: Early clinical results of anterolateral ligament (ALL) reconstruction are promising, but concerns exist due to high rates of complications after other types of lateral extra-articular tenodesis. The rate of surgery after combined anterior cruciate ligament (ACL) and ALL reconstruction is not known. PURPOSE: To determine the rate of reoperation after combined ACL and ALL reconstruction. STUDY DESIGN: Case series; Level of evidence, 4...
June 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28599883/uterine-sparing-laparoscopic-resection-of-accessory-cavitated-uterine-masses
#5
Ann Peters, Noah B Rindos, Richard S Guido, Nicole M Donnellan
To demonstrate surgical techniques utilized during uterine-sparing laparoscopic resections of accessory cavitated uterine masses (ACUM) BACKGROUND: ACUM represent a rare uterine entity observed in premenopausal women suffering from dysmenorrhea and recurrent pelvic pain. The diagnosis is made when an isolated extra-cavitated uterine mass is resected from an otherwise normal appearing uterus with unremarkable endometrial lumen and adnexal structures. Pathologic confirmation requires an accessory cavity lined with endometrial epithelium (and corresponding glands and stroma) filled with chocolate-brown fluid...
June 6, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28585844/-abdominal-pregnancy-at-a-patient-after-cesarean-section-bilateral-salpingectomy-and-embryotransfer
#6
E Suchánková, J Pavlásek, I Bydžovská, M Lubušký
OBJECTIVE: Presentation of rare complication following the assisted reproduction at a patient after cesarean section and bilateral salpingectomy. DESIGN: Case report. SETTINGS: Department of Obstetrics and Gynaecology, Regional Hospital Liberec, a. s.; Department of Obstetrics and Gynaecology, Palacky University Hospital, Olomouc. OBSERVATION: Pregnant woman, 26-years old, primiparous, with history of cesarean section and bilateral salpingectomy, was referred from the assisted reproduction centre to solve suspicion of molar intrauterine pregnancy...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28580267/fatigue-behavior-of-nitinol-anterior-cruciate-ligament-graft-and-inappropriate-femoral-tunnel-placement-single-stage-revision-anterior-cruciate-ligament-reconstruction-surgery
#7
Fatih Karaaslan, Sinan Karaoğlu
Anterior cruciate ligament (ACL) injury is the most common ligament injury in the knee, and progressive instability and disability may develop in a significant number of patients. The incidence of ACL reconstruction is rapidly increasing, as is the number of failures. Although ACL reconstruction is a common procedure, less than satisfactory outcomes have been reported to occur in up to 25% of patients. The reasons for clinical failure after ACL reconstruction are numerous but can be broadly separated into 3 categories: technical, biological, and mechanical failures...
April 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28577089/effects-of-bone-marrow-multipotent-mesenchymal-stromal-cells-and-their-secretory-products-on-microcirculation-in-the-broad-ligament-of-the-uterus-of-wistar-rats-during-experimental-chronic-genital-inflammation
#8
V I Konenkov, Yu I Borodin, T I Dergacheva, A V Shurlygina, M V Tenditnik, E V Starkova, O V Poveshchenko, A P Lykov
Effects of bone marrow multipotent mesenchymal stromal cells and their secretory products released into the conditioned medium on microcirculatory bed in the broad ligament of the uterus were studied in Wistar rats with chronic genital inflammation. Opposite changes in the parameters of microcirculation and lymphatic drainage in the broad ligament of the uterus were observed after administration of cells and conditioned medium via different routes, which should be taken into account during the treatment of inflammatory and degenerative processes in the pelvic organs...
June 3, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28559005/tibial-insertions-of-the-anterior-cruciate-ligament-and-the-anterior-horn-of-the-lateral-meniscus-a-histological-and-computed-tomographic-study
#9
Masashi Kusano, Yasukazu Yonetani, Tatsuo Mae, Ken Nakata, Hideki Yoshikawa, Konsei Shino
BACKGROUND: A positional relationship between the anterior cruciate ligament (ACL) and the anterior horn of the lateral meniscus (AHLM) has not previously been a topic of interest in the literature because the AHLM is already known to be obviously adjacent to the ACL and is assumed as a lateral border. The objective of this study was to investigate the positional anatomic relationship between the ACL and AHLM by histological evaluation of sequential slices and computed tomography (CT) of the tibial insertion sites...
May 27, 2017: Knee
https://www.readbyqxmd.com/read/28529572/recurrent-female-adnexal-tumor-of-probable-wolffian-origin-treated-with-debulking-surgery-imatinib-and-paclitaxel-carboplatin-combination-chemotherapy-a-case-report
#10
Akihiko Wakayama, Hirofumi Matsumoto, Hajime Aoyama, Masanao Saio, Ayumi Kumagai, Takuma Ooyama, Morihiko Inamine, Yoichi Aoki
In view of the small number of recurrent and metastatic cases of female adnexal tumors of probable Wolffian origin (FATWO), there is a distinct lack of evidence to support recommendations regarding treatment. In the present study, a 37-year-old female was diagnosed with a left adnexal tumor and underwent a left salpingo-oophorectomy (SO). The tumor was found to arise from the left tubal fimbria and extend to the posterior leaf of the broad ligament. Pathological examination identified a number of solid, tubular and cystic architectures, with areas of hyalinization, hemorrhage and necrosis...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28524158/sequencing-of-dicer1-in-sarcomas-identifies-biallelic-somatic-dicer1-mutations-in-an-adult-onset-embryonal-rhabdomyosarcoma
#11
Leanne de Kock, Barbara Rivera, Timothée Revil, Paul Thorner, Catherine Goudie, Dorothée Bouron-Dal Soglio, Catherine S Choong, John R Priest, Paul J van Diest, Jantima Tanboon, Anja Wagner, Jiannis Ragoussis, Peter Fm Choong, William D Foulkes
BACKGROUND: Sarcomas are rare and heterogeneous cancers. We assessed the contribution of DICER1 mutations to sarcoma development. METHODS: The coding region of DICER1 was sequenced in 67 sarcomas using a custom Fluidigm Access Array. The RNase III domains were Sanger sequenced in six additional sarcomas to identify hotspot DICER1 variants. RESULTS: The median age of sarcoma diagnosis was 45.7 years (range: 3 months to 87.4 years). A recurrent embryonal rhabdomyosarcoma (ERMS) of the broad ligament, first diagnosed at age 23 years, harboured biallelic pathogenic somatic DICER1 variants (1 truncating and 1 RNase IIIb missense)...
June 6, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28476360/editorial-commentary-do-we-need-to-look-for-isometry-in-anterolateral-ligament-reconstruction
#12
EDITORIAL
Bertrand Sonnery-Cottet
In a recent computer simulation study, authors attempted to calculate the optimal femoral and tibial insertion points for an almost isometric anterolateral ligament (ALL) reconstruction. However, it is important to note that the tibial insertion of the ALL is broad and cannot be defined by a single point. Furthermore, previous studies have demonstrated that the ALL shows a nonisometric behavior during flexion-extension, tight close to extension to control the rotation (and the pivot shift), and slack in flexion to allow physiological internal rotation...
May 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28459372/laparoscopic-subperitoneal-injection-of-chemo-loaded-particles-lowers-tumor-growth-on-a-rabbit-model-of-peritoneal-carcinomatosis
#13
Florentina Pascale, Afshin Fazel, Julien Namur, Saida-Homayra Ghegediban, Hadrian D'Inca, Michel Wassef, Laurence Moine, Alexandre Laurent
The purpose of our study was to assess the effect of controlled-release chemotherapy on the growth and viability of peritoneal carcinomatosis treated by subperitoneal injection in a rabbit VX2 model. A model of peritoneal carcinomatosis was created by laparoscopic injection of VX2 tumor in the left and right broad ligaments of 12 White New Zealand rabbits. At day 12, each tumor was randomly treated with a peritumoral injection of 0.5 mL microspheres loaded with doxorubicin (DEM-DOX) or unloaded (DEM-BLAND)...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28450099/topographical-anatomy-of-the-distal-ulna-attachment-of-the-radioulnar-ligament
#14
Won-Jeong Shin, Jong-Pil Kim, Hun-Mu Yang, Eun-Young Lee, Jai-Hyang Go, Kang Heo
PURPOSE: The deep component of the distal radioulnar ligament provides translational stability and rotational guidance to the forearm. However, controversy exists regarding the importance of this structure as well as the nature of its attachment to the distal ulna. We aimed to evaluate the topographic anatomy of the distal ulna attachment of both the superficial and the deep components of the radioulnar ligament and to assess the relationship between its internal and its external morphometry...
April 25, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28434748/predicting-stage-2-of-calving-in-holstein-friesian-heifers
#15
K Lange, C Fischer-Tenhagen, W Heuwieser
The objective of this study was to predict stage 2 of calving in Holstein-Friesian heifers. Interobserver reliability and predictive values of relevant signs of imminent parturition (i.e., tail raising, stepping, clear and bloody vaginal discharge, turning the head toward the abdomen, and lying lateral with abdominal contractions) were determined. In the first experiment 32 heifers were included. Three investigators participated as observers in the study. They walked through the precalving pen in pairs and observed pregnant heifers (≥267 d pregnant)...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28400880/arthroscopic-findings-in-anterior-shoulder-instability
#16
REVIEW
Michael Hantes, Vasilios Raoulis
BACKGROUND: In the last years, basic research and arthroscopic surgery, have improved our understanding of shoulder anatomy and pathology. It is a fact that arthroscopic treatment of shoulder instability has evolved considerably over the past decades. The aim of this paper is to present the variety of pathologies that should be identified and treated during shoulder arthroscopy when dealing with anterior shoulder instability cases. METHODS: A review of the current literature regarding arthroscopic shoulder anatomy, anatomic variants, and arthroscopic findings in anterior shoulder instability, is presented...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28384972/comparison-of-cone-beam-computed-tomography-and-multi-slice-computed-tomography-image-quality-of-human-dried-mandible-using-10-anatomical-landmarks
#17
Samira Saati, Fatemeh Kaveh, Shiva Yarmohammadi
INTRODUCTION: Cone Beam Computed Tomography (CBCT) has gained a broad acceptance in dentomaxillofacial imaging. Computed Tomography (CT) is another imaging modality for diagnosis and preoperative assessments of the head and neck region. AIM: Considering the increased radiation exposure and high cost of CT, this study sought to subjectively assess the image quality of CBCT and Multi Slice CT (MSCT). MATERIALS AND METHODS: A dry human mandible was scanned by five CBCT systems (New Tom 3G, Scanora, CRANEX 3D, Promax and Galileos) and one MSCT system...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28351194/extraovarian-fibroma-with-minor-sex-cord-elements
#18
Makiko Omori, Tetsuo Kondo, Jiro Fukushima, Megumi Oi, Yumika Watanabe, Tadao Nakazawa, Akihiko Hashi, Shuji Hirata
Extraovarian sex cord-stromal tumor is an exceedingly uncommon entity that may cause a diagnostic dilemma clinically. We report a case of extraovarian fibroma with minor sex cord elements arising in the left broad ligament. The patient was a 66-year-old woman presenting with an intra-abdominal solid mass near the left ovary on magnetic resonance imaging. The tumor was located in the left broad ligament in contact with the left ovary and fallopian tube based on laparotomy findings. Histological examination revealed that the tumor was a fibroma that contained cell nests with aggregates resembling the Call-Exner bodies of granulosa cell tumors and irregularly shaped cell nests composed of undifferentiated sex cord-type cells...
March 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28348779/unusual-case-of-pelvic-hydatid-cyst-of-broad-ligament-mimicking-an-ovarian-tumour
#19
Alaa Abdullah, Reema Alsafi, Jamshaid Iqbal, Vincent Rotimi
INTRODUCTION: The diagnosis of hydatid cyst in female genital tract is rare and difficult. A high degree of clinical suspicion is needed for pre-operative investigations to exclude hydatid cyst of female pelvis. The objective of this presentation is to highlight a pelvic hydatid cyst that presented as an ovarian tumour. CASE PRESENTATION: A 22-year-old female, presented with constipation and haematuria with acute urinary retention. On examination, a mass measuring 15×13 cm was palpable in the left iliac region reaching up to the umbilicus...
August 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28348178/craniofacial-tissue-engineering
#20
Weibo Zhang, Pamela Crotty Yelick
The craniofacial complex is composed of fundamental components such as blood vessels and nerves, and also a variety of specialized tissues such as craniofacial bones, cartilages, muscles, ligaments, and the highly specialized and unique organs, the teeth. Together, these structures provide many functions including speech, mastication, and aesthetics of the craniofacial complex. Craniofacial defects not only influence the structure and function of the jaws and face, but may also result in deleterious psychosocial issues, emphasizing the need for rapid and effective, precise, and aesthetic reconstruction of craniofacial tissues...
March 27, 2017: Cold Spring Harbor Perspectives in Medicine
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