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https://www.readbyqxmd.com/read/28799491/exercise-programmes-for-osteoarthritis-with-different-localization
#1
Sevdalina Lambova
Therapeutic exercises in osteoarthritis (OA) are therapeutic approach with proven efficacy. On the other hand, the different disease form, the lack of established consensus and system for patient education limit the widespread use of therapeutic exercises in clinical practice. The mechanisms of action of therapeutic exercise in OA include the following components e. g., neuromuscular (improvement of proprioception, muscle strength and joint stability), intra-articular (prevention of cartilage degeneration, antiinflammatory effect, improvement of the quality of the joint fluid), periarticular, general health with reduction of cardiovascular risk and psychological components...
August 10, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28782498/results-of-arthroscopic-treatment-of-chondral-delamination-in-femoroacetabular-impingement-with-bone-marrow-stimulation-and-bst-cargel-%C3%A2
#2
Mahmoud Tahoun, Tamer Aly Shehata, Inmaculada Ormazabal, Jesús Mas, Javier Sanz, Marc Tey Pons
OBJECTIVES: The purpose of this study is to show the preliminary results of using chitosan-based scaffold (BST-CarGel(®)) with microfracture for treatment of acetabular chondral delamination associated with femoroacetabular impingement. METHODS: A prospective study was performed on 13 hips. Patients were selected in the age group between 18 and 50 years. Patients with delamination of acetabular cartilage associated with femoroacetabular impingement received arthroscopic debridement and microfracture technique...
2017: SICOT-J
https://www.readbyqxmd.com/read/28766055/non-synonymous-wnt16-polymorphisms-alleles-are-associated-with-different-osteoarthritis-phenotypes
#3
Carmen García-Ibarbia, Sara Neila, Carlos Garcés, Maria A Alonso, María T Zarrabeitia, Carmen Valero, Fernando Ortiz, José A Riancho
Hereditary factors have a strong influence on osteoarthritis (OA). The Wnt pathway is involved in bone and cartilage homeostasis. Hence, we hypothesized that allelic variations of WNT16 could influence the OA phenotype. We studied 509 Caucasian patients undergoing joint replacement due to severe primary OA. Radiographs were used to classify the OA as atrophic or hypertrophic. Two nonsynonymous polymorphisms of WNT16 (rs2707466 and rs2908004) were analyzed. The association between the genotypes and the OA phenotype was analyzed by logistic regression and adjusted for age and body mass index...
August 1, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28764769/anabolic-role-of-lysyl-oxidase-like-2-in-cartilage-of-knee-and-temporomandibular-joints-with-osteoarthritis
#4
Weam Alshenibr, Mustafa M Tashkandi, Saqer F Alsaqer, Yazeed Alkheriji, Amelia Wise, Sadanand Fulzele, Pushkar Mehra, Mary B Goldring, Louis C Gerstenfeld, Manish V Bais
BACKGROUND: Lysyl oxidase like-2 (LOXL2) is a copper-dependent amine oxidase. Our previous studies showed that LOXL2 is elevated during mouse fracture healing. The goal of this study was to evaluate the potential of LOXL2 to act as an anabolic agent in cartilage affected by osteoarthritis (OA). METHODS: LOXL2 was visualized in tissues from human knee and hip joints and temporomandibular joints (TMJ) by immunofluorescence. The activity of LOXL2 in human articular and TMJ chondrocytes was assessed by cell-based assays, microarray analysis, and RT-qPCR, and LOXL2-mediated activation of NF-κB and extracellular signal-related kinase (ERK) signaling pathways was measured by western blotting...
August 2, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28762649/associations-between-systemic-bone-mineral-density-knee-cartilage-defects-and-bone-marrow-lesions-in-patients-with-knee-osteoarthritis
#5
Qicui Zhu, Jianhua Xu, Kang Wang, Jingyu Cai, Juan Wu, Jiale Ren, Shuang Zheng, Changhai Ding
AIM: The relationship between bone mineral density (BMD) and osteoarthritis (OA) remains controversial. This study aimed to explore the cross-sectional associations between BMD at the total body, hip and spine and joint structural abnormalities including cartilage defects and bone marrow lesions (BMLs) in patients with knee OA. METHOD: One hundred and eight-five subjects with symptomatic knee OA were included in this study. T2-weighted fast spin echo magnetic resonance imaging was used to assess knee cartilage defects and BMLs...
August 1, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28762536/a-novel-mr-based-method-for-detection-of-cartilage-delamination-in-femoroacetabular-impingement-patients
#6
Michael A Samaan, Valentina Pedoia, Alan L Zhang, Matthew C Gallo, Thomas M Link, Richard B Souza, Sharmila Majumdar
In this study, quantitative magnetic resonance based measurements were used to evaluate T1ρ and T2 mapping and heterogeneity in femoroacetabular impingement (FAI) patients with acetabular cartilage delamination and to determine the ability of these quantitative MR-based measurements in detecting delamination. Unilateral hip joint MR-scans of 36 FAI patients with arthroscopically-confirmed acetabular cartilage delamination and 36 age, gender and BMI matched controls were obtained. T1ρ and T2 mapping and heterogeneity of the hip joint articular cartilage were assessed in both groups using voxel-based relaxometry (VBR)...
August 1, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28762158/the-validity-and-accuracy-of-mri-arthrogram-in-the-assessment-of-painful-articular-disorders-of-the-hip
#7
Aysha Rajeev, Wim Tuinebreijer, Abdalla Mohamed, Mike Newby
The assessment of a patient with chronic hip pain can be challenging. The differential diagnosis of intra-articular pathology causing hip pain can be diverse. These includes conditions such as osteoarthritis, fracture, and avascular necrosis, synovitis, loose bodies, labral tears, articular pathology and, femoro-acetabular impingement. Magnetic resonance imaging (MRI) arthrography of the hip has been widely used now for diagnosis of articular pathology of the hip. A retrospective analysis of 113 patients who had MRI arthrogram and who underwent hip arthroscopy was included in the study...
July 31, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28752488/wnt-%C3%AE-catenin-signaling-in-osteoarthritis-and-in-other-forms-of-arthritis
#8
REVIEW
Yachuan Zhou, Tingyu Wang, John L Hamilton, Di Chen
PURPOSE OF REVIEW: Arthritis defines a large group of diseases primarily affecting the joint. It is the leading cause of pain and disability in adults. Osteoarthritis (OA) affecting the knee or hip is the most common form among over 100 types of arthritis. Other types of arthritis include erosive hand OA, temporomandibular joint (TMJ) OA, facet joint OA, diffuse idiopathic skeletal hyperostosis (DISH), and spondyloarthritis (SpA). However, the specific molecular signals involved in the development and progression of OA and related forms of arthritis remain largely unknown...
September 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28748363/type-ii-sciatic-nerve-variant-an-unexpected-interventional-hazard
#9
Graeme Thompson, Ruan Visagie
A 12-year-old girl presented with a 1-week history of right hip pain. MRI revealed a lesion in the incompletely fused posterior triradiate cartilage of the right acetabulum with imaging characteristics of an osteoid osteoma. The surgeon requested guidewire placement under CT guidance for lesion drilling. The CT approach was planned to avoid the usual course of the sciatic nerve, and the lesion was successfully removed and confirmed at histology to be an osteoid osteoma. At a follow-up visit, MRI showed no recurrence but demonstrated an abnormal common peroneal nerve from the sciatic notch to the popliteal fossa with denervation oedema in the tibias anterior and peroneal musculature...
July 26, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28741137/protection-of-the-proximal-articular-cartilage-during-percutaneous-thermal-ablation-of-acetabular-metastasis-using-temperature-monitoring
#10
Salem Bauones, Julien Garnon, Basavaraj Chari, Roberto L Cazzato, Georgia Tsoumakidou, Jean Caudrelier, Guillaume Koch, Afshin Gangi
OBJECTIVE: To review our initial experience in acetabular cartilage protection from thermal injury with temperature monitoring during percutaneous image-guided tumor thermal ablation. MATERIALS AND METHODS: Between June 2015 and December 2016, three consecutive oncologic patients (mean age 58 years; range 48-67 years) with acetabular bone metastasis underwent percutaneous image-guided thermal ablation procedures along with hip joint cartilage thermal monitoring...
July 24, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28719561/arterial-topographic-anatomy-near-the-femoral-head-neck-perforation-with-surgical-relevance
#11
Paulo Rego, Vasco Mascarenhas, Diego Collado, Ana Coelho, Luis Barbosa, Reinhold Ganz
BACKGROUND: Knowledge of the vascular supply of the femoral head is crucial for hip-preserving surgical procedures. The critical area for reshaping cam deformity is at the retinacular vessel penetration, an area with ill-defined topographic anatomy. We performed a cadaver study of the extension of the lateral retinaculum near the head-neck junction, distribution of the arterial vascular foramina, and initial intracapital course of these vessels. METHODS: In 16 fresh proximal parts of the femur without head-neck deformities, the deep branch of the medial femoral circumflex artery was injected with gadolinium for magnetic resonance imaging (MRI) sequences to identify arterial structures...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28715906/t2-mapping-provides-information-that-is-statistically-comparable-to-an-arthroscopic-evaluation-of-acetabular-cartilage
#12
Patrick Morgan, Mikko J Nissi, John Hughes, Shabnam Mortazavi, Jutta Ellerman
Objectives The purpose of this study was to validate T2* mapping as an objective, noninvasive method for the prediction of acetabular cartilage damage. Methods This is the second step in the validation of T2*. In a previous study, we established a quantitative predictive model for identifying and grading acetabular cartilage damage. In this study, the model was applied to a second cohort of 27 consecutive hips to validate the model. A clinical 3.0-T imaging protocol with T2* mapping was used. Acetabular regions of interest (ROI) were identified on magnetic resonance and graded using the previously established model...
July 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28706807/labral-gracilis-tendon-allograft-reconstruction-and-cartilage-regeneration-scaffold-for-an-uncontained-acetabular-cartilage-defect-of-the-hip
#13
Laurel E MacInnis, Ahmed Al Hussain, Catherine Coady, Ivan H Wong
Hip cartilage injuries are very common, with rates as high as 50% having been reported in some series; abnormal femoral acetabular contact can result in a full-thickness cartilage defect or labral lesion. The prevalence of labral lesions can be as high as 55%. This Technical Note describes an arthroscopic technique to reconstruct an uncontained, full-thickness, focal cartilage defect of the acetabulum, with reconstruction of the missing labrum using a gracilis allograft and use of a biological liquid scaffold for cartilage reconstruction...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28688198/study-of-the-interactions-between-proximal-femur-3d-bone-shape-cartilage-health-and-biomechanics-in-patients-with-hip-osteoarthritis
#14
Valentina Pedoia, Michael A Samaan, Gaurav Inamdar, Matthew C Gallo, Richard B Souza, Sharmila Majumdar
In this study quantitative MRI and gait analysis were used to investigate the relationships between proximal femur 3D bone shape, cartilage morphology, cartilage biochemical composition, and joint biomechanics in subject with hip Osteoarthritis (OA). Eighty subjects underwent unilateral hip MR-imaging: T1ρ and T2 relaxation times were extracted through voxel based relaxometry and bone shape was assessed with 3D MRI-based statistical shape modeling. In addition, 3D gait analysis was performed in seventy-six of the studied subjects...
July 8, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28673601/femoroacetabular-impingement-causes-osteoarthritis-of-the-hip-by-migration-and-micro-instability-of-the-femoral-head
#15
Henk Eijer, Tom Hogervorst
Femoroacetabular impingement is the condition whereby parts of the proximal femur mechanically collide with the acetabular rim leading to adjacent and contrecoup acetabular damage. Evidence is growing that at least for cam impingement, and perhaps less so for pincer impingement, there is a relation to the development of osteoarthritis. It has been demonstrated that surgery for impingement can improve function and decrease pain. Intuitively, it would then make sense that surgical intervention would prevent further degeneration...
July 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28666512/obturator-internus-abscess-with-ipsilateral-septic-hip-arthritis
#16
Sang Hyun Park, Joo Yong Kim, Gyu Min Kong, Sang Myung Roh
Obturator internus muscle (OIM) abscess is an uncommon condition often mistaken for bacterial infection of the hip joint. If the OIM abscess is accompanied by a septic hip, it becomes more difficult to make a diagnosis. Surgical drainage of OIM abscess is difficult because it is located at a deep part of the pelvic cavity. Therefore, intravenous antibiotic therapy or image-guided aspiration were used as a treatment method instead of surgical drainage. When drainage of the abscess was inadequate, prolonged antibiotic treatment was necessary...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28652829/patellofemoral-pain-in-athletes
#17
REVIEW
Wolf Petersen, Ingo Rembitzki, Christian Liebau
Patellofemoral pain (PFP) is a frequent cause of anterior knee pain in athletes, which affects patients with and without structural patellofemoral joint (PFJ) damage. Most younger patients do not have any structural changes to the PFJ, such as an increased Q angle and a cartilage damage. This clinical entity is known as patellofemoral pain syndrome (PFPS). Older patients usually present with signs of patellofemoral osteoarthritis (PFOA). A key factor in PFPS development is dynamic valgus of the lower extremity, which leads to lateral patellar maltracking...
2017: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/28650110/reproducibility-of-in-vivo-magnetic-resonance-imaging-t1-rho-and-t2-relaxation-time-measurements-of-hip-cartilage-at-3-0t-in-healthy-volunteers
#18
Angeline Nemeth, Lucy Di Marco, Florent Boutitie, Michael Sdika, Denis Grenier, Muriel Rabilloud, Olivier Beuf, Jean-Baptiste Pialat
PURPOSE: To assess the T1 ρ and T2 values in the hip cartilage of healthy volunteers and to evaluate the reproducibility of these measurements. MATERIALS AND METHODS: The right hip joint of 30 asymptomatic volunteers was explored with 3T magnetic resonance imaging (MRI). Quantitative 3D T1 ρ- and T2 -maps sequences were repeated twice with a 30-minute delay (immediate reproducibility). The same protocol was repeated 14 days later (short-term reproducibility). Immediate and short-term reproducibility were estimated using coefficients of variation and correlation concordance coefficients (CCC)...
June 26, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28630737/mesenchymal-stem-cell-therapy-in-the-treatment-of-hip-osteoarthritis
#19
Rodrigo Mardones, Claudio M Jofré, L Tobar, José J Minguell
This study was performed to investigate the safety and efficacy of the intra-articular infusion of ex vivo expanded autologous bone marrow-derived mesenchymal stem cells (BM-MSC) to a cohort of patients with articular cartilage defects in the hip. The above rationale is sustained by the notion that MSCs express a chondrocyte differential potential and produce extracellular matrix molecules as well as regulatory signals, that may well contribute to cure the function of the damaged hip joint. A cohort of 10 patients with functional and radiological evidences of hip osteoarthritis, either in one or both legs, was included in the study...
July 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/28630723/outcome-after-arthroscopic-labral-surgery-in-patients-previously-treated-with-periacetabular-osteotomy-a-follow-up-study-of-43-patients
#20
Charlotte Hartig-Andreasen, Torsten G Nielsen, Bent Lund, Kjeld Søballe, Martin Lind
To identify factors predicting failure after hip arthroscopy in patients with previous periacetabular osteotomy (PAO) defined as a conversion to total hip replacement (THR) and to evaluate the patient reported outcome scores. Of 55 hips treated with hip arthroscopy after PAO from Aug 2008 to 2012 at Aarhus University Hospital, 43 hips were included (median age: 36.1 yrs, range 16.3-56.9 yrs). Indications were unacceptable pain, a positive FABER and impingement test and signs of labral damage on MR-arthrography...
January 2017: Journal of Hip Preservation Surgery
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