keyword
https://read.qxmd.com/read/38457574/sodium-citrate-versus-sodium-bicarbonate-for-metabolic-acidosis-in-patients-with-chronic-kidney-disease-a-randomized-controlled-trial
#21
RANDOMIZED CONTROLLED TRIAL
Bogdan Marian Sorohan, Bogdan Obrișcă, Roxana Jurubiță, Gabriela Lupușoru, Camelia Achim, Andreea Andronesi, Georgiana Frățilă, Andreea Berechet, Georgia Micu, Gener Ismail
BACKGROUND: Metabolic acidosis (MA) is frequently associated with chronic kidney disease (CKD) progression. Our aim was to compare the effect of oral sodium citrate (SC) with that of oral sodium bicarbonate (SB) on renal function and serum bicarbonate correction, as well as to evaluate their safety profile in patients with MA of CKD. METHODS: We conducted a prospective, single-center, randomized 1:1, parallel, controlled, unblinded clinical trial of 124 patients with MA and CKD stages 3b and 4...
March 8, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38454211/destructive-disasters-trauma-crush-syndrome-and-beyond
#22
JOURNAL ARTICLE
Mehmet Şükrü Sever, Yusuf Alper Katı, Ufuk Özkaya
Orthopedic injuries, especially fractures of long bones as well as multiple fractures and comminuted fractures, are very common after destructive disasters (e.g., earthquakes, wars, and hurricanes). Another frequent problem is traumatic rhabdomyolysis, which may result in crush syndrome, the second most frequent cause of death after direct traumatic impact following earthquakes. To improve outcomes, interventions should be initiated even before extrication of the victims, which include maintenance of airway patency and spine stabilization, stopping traumatic bleeding by any means, and initiating fluid resuscitation...
November 2023: Acta Orthopaedica et Traumatologica Turcica
https://read.qxmd.com/read/38451476/off-the-shelf-synthetic-biodegradable-grafts-transform-in-situ-into-a-living-arteriovenous-fistula-in-a-large-animal-model
#23
JOURNAL ARTICLE
Paul J Besseling, Wojciech Szymczyk, Martin Teraa, Raechel J Toorop, Dan Jing Wu, Rob C H Driessen, Arturo M Lichauco, Henk M Janssen, Melanie van de Kaa, Krista den Ouden, Petra M de Bree, Joost O Fledderus, Carlijn V C Bouten, Gert J de Borst, Patricia Y W Dankers, Marianne C Verhaar
Current vascular access options require frequent interventions. In situ tissue engineering may overcome these limitations by combining the initial success of synthetic grafts with the long-term advantages of autologous vessels by using biodegradable grafts that transform into autologous vascular tissue at the site of implantation. Scaffolds(6mm-Ø) made of supramolecular polycarbonate-bisurea(PC-BU), with a polycaprolactone(PCL) anti-kinking-coil, were implanted between the carotid artery and jugular vein in goats...
March 7, 2024: Advanced Healthcare Materials
https://read.qxmd.com/read/38444170/obinutuzumab-is-effective-for-the-treatment-of-frequently-relapsing-steroid-dependent-minimal-change-disease-in-adults
#24
JOURNAL ARTICLE
Li Jin, Xueying Liu, Huixian Li, Xiangyun Dang, Zhigang Wang, Dan Niu, Xiaotian Zhang, Jiping Sun, Dapeng Hao, Wanhong Lu
No abstract text is available yet for this article.
March 5, 2024: Nephrology, Dialysis, Transplantation
https://read.qxmd.com/read/38443857/the-association-between-new-inflammation-markers-and-frequent-peritoneal-dialysis-associated-peritonitis
#25
JOURNAL ARTICLE
Jing Tang, Dongxue Wang, Yun Chen, Jinhong Feng
OBJECTIVE: To validate an association between new inflammation and frequent peritoneal dialysis-associated peritonitis (PDAP). MATERIALS AND METHODS: In China, retrospective clinical data were collected on 208 patients who received continuous ambulatory peritoneal dialysis (CAPD) between 2010 and 2021. The patients were divided into two groups: non-frequent PDAP (the interval between two peritonitis episodes of more than one year) and frequent PDAP (the interval between two peritonitis episodes of less than one year)...
March 5, 2024: BMC Nephrology
https://read.qxmd.com/read/38436294/rotational-thrombectomy-versus-balloon-maceration-in-dialysis-access-salvage
#26
JOURNAL ARTICLE
Jee Hyuk Byun, Andrew Rennie, Junjian Huang, Junaid Raja
BACKGROUND: Although end stage renal disease patients who undergo hemodialysis frequently experience dialysis-associated thrombotic complications, there remains a paucity of literature comparing the efficacy of different endovascular salvage techniques for grafts and fistulas. This study aims to compare primary patency in dialysis access following salvage mechanical thrombolysis/thrombectomy with a rotational thrombolysis device versus balloon maceration. METHODS: Using a database of patient records at a tertiary medical center, all patients who underwent rotational thrombectomy with the Cleaner XT™ Rotational Thrombectomy System for endovascular salvage of arteriovenous fistula or arteriovenous graft from August 2016 to July 2022 were included in the population...
March 4, 2024: Journal of Vascular Access
https://read.qxmd.com/read/38433228/the-error-of-estimated-gfr-in-predialysis-care
#27
JOURNAL ARTICLE
Beatriz Escamilla-Cabrera, Sergio Luis-Lima, Eduardo Gallego-Valcarce, Nuria Victoria Sánchez-Dorta, Natalia Negrín-Mena, Laura Díaz-Martín, Coriolano Cruz-Perera, Ana Monserrat Hernández-Valles, Federico González-Rinne, María José Rodríguez-Gamboa, Sara Estupiñán-Torres, Rosa Miquel-Rodríguez, María Ángeles Cobo-Caso, Patricia Delgado-Mallén, Gema Fernández-Suárez, Ana González-Rinne, Grimanesa Hernández-Barroso, Alejandra González-Delgado, Armando Torres-Ramírez, Alejandro Jiménez-Sosa, Alberto Ortiz, Flavio Gaspari, Domingo Hernández-Marrero, Esteban Luis Porrini
The error of estimated glomerular filtration rate (eGFR) and its consequences in predialysis are unknown. In this prospective multicentre study, 315 predialysis patients underwent measured GFR (mGFR) by the clearance of iohexol and eGFR by 52 formulas. Agreement between eGFR and mGFR was evaluated by concordance correlation coefficient (CCC), total deviation index (TDI) and coverage probability (CP). In a sub-analysis we assessed the impact of eGFR error on decision-making as (i) initiating dialysis, (ii) preparation for renal replacement therapy (RRT) and (iii) continuing clinical follow-up...
March 3, 2024: Scientific Reports
https://read.qxmd.com/read/38431802/healthcare-associated-infections-after-neurosurgical-procedures-in-ukraine-a-multicentre-study-2020-2022
#28
JOURNAL ARTICLE
Aidyn G Salmanov, Dmytro V Shchehlov, Maryna Mamonova, Ihor M Bortnik, Nadiia B Chabanovych, Yaroslav E Kudelskyi, Daria Chekhunova
OBJECTIVE: Aim: To investigate the epidemiology, microbiology, and risk factors for healthcare-associated infections (HAIs) after a neurosurgical procedure in Ukraine. PATIENTS AND METHODS: Materials and Methods: Prospective multicentre surveillance was conducted from January 2020 to December 2022 in 10 regional hospitals of Ukraine. Definitions of HAIs were adapted from the Centers for Disease Control and Prevention's National Healthcare Safety Network. RESULTS: Results: Of 8,623 neurosurgical patients, 1,579 (18...
2024: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/38425707/actioning-the-findings-of-hard-endpoint-clinical-trials-as-they-emerge-in-the-realm-of-chronic-kidney-disease-care-a-review-and-a-call-to-action
#29
REVIEW
Giovanni F M Strippoli, Suetonia C Green
Fewer than half of patients treated with hemodialysis survive 5 years. Multiple therapeutics are used to address the complications of advanced chronic kidney disease but most have not been found to improve clinical outcomes. Clinical trials of treatment innovations for chronic kidney diseases and dialysis care have been suboptimal in number and quality. Recent trials are changing this trend. Practice and policy change when new evidence emerges remains frequently impeded by resource and organizational constraints and accordingly, clinical practice guidelines are updated years or decades after definitive evidence is produced...
February 2024: Clinical Kidney Journal
https://read.qxmd.com/read/38418259/a-cost-effective-approach-to-resistant-av-fistula-stenosis-successful-treatment-using-coronary-opn-nc%C3%A2-balloon-in-a-low-income-setting
#30
Kanhai Lalani, M Sudhakar Rao, M Harsha Sagar, Padmakumar R
Stenosis in the anastomotic site or venous limb of an arteriovenous fistula (AVF) is the most frequent cause of AVF failure. Percutaneous angioplasty with a standard or high-pressure balloon is the first-line treatment for AVF stenosis due to its higher technical success rate (90%) and lower complication rate (4%). Almost 20% of stenosis cases are resistant or undilatable by regular-pressure balloon angioplasty due to fibrosis, leading to technical failure or restenosis. Alternative therapies, such as atherectomy devices or cutting balloons, are expensive and difficult to obtain in low-income developing countries...
February 28, 2024: Seminars in Dialysis
https://read.qxmd.com/read/38413296/risk-factors-for-mortality-in-children-with-hemorrhagic-cystitis-after-hematopoietic-transplant
#31
JOURNAL ARTICLE
Daniel Salevitz, Lucia Mirea, Gwen M Grimsby
INTRODUCTION: Hemorrhagic cystitis (HC) is a devastating complication of bone marrow (BMT) and stem cell transplant (SCT). Much of the literature has focused on exclusively adult patient populations, with limited evidence regarding risk factors for mortality and morbidity among pediatric HC patients. OBJECTIVE: To examine factors associated with all-cause mortality in children with HC after BMT/SCT. METHODS: The Pediatric Health Information System database was queried for patients with ICD-9/10 codes for hematopoietic transplant and gross hematuria, hematuria unspecified, or cystitis with hematuria...
February 15, 2024: Journal of Pediatric Urology
https://read.qxmd.com/read/38413047/the-use-of-lung-ultrasound-in-evaluation-of-extravascular-lung-water-in-hemodialysis-patients-systematic-review-and-meta-analysis
#32
REVIEW
Anas Elgenidy, Mostafa Atef Amin, Ahmed K Awad, Abdullah Emad, Abdelrahman Nassar, Omar Alomari, Radwa Ibrahim, Faeq Husain-Syed, Mostafa G Aly
RATIONALE AND OBJECTIVES: Determining dry weight is crucial for optimizing hemodialysis, influencing efficacy, cardiovascular outcomes, and overall survival. Traditional clinical assessment methods for dry weight, relying on factors such as blood pressure and edema, frequently lack reliability. Lung ultrasound stands out as a promising tool for assessing volume status, given its non-invasiveness and reproducibility. This study aims to explore the role of Lung ultrasound in evaluating the impact of hemodialysis and ultrafiltration on extravascular lung water, with a specific focus on changes in B-lines post-hemodialysis compared to pre-hemodialysis...
February 27, 2024: Hemodialysis International
https://read.qxmd.com/read/38406109/etiological-factors-affecting-single-versus-multiple-tunneled-hemodialysis-catheter-cuff-extrusions-in-the-saudi-population
#33
JOURNAL ARTICLE
Hammad Raza, Muhammad Nauman Hashmi, Muhammad A Khan, Manuel Troncoso, Agamon Christallone, Jawad Alhammouri, Mohamed Hafez, Muhammad Shakeel Khan, Fayez Hejaili
OBJECTIVE: To identify underlying factors associated with single versus multiple expulsions of tunneled hemodialysis catheter cuffs and their associated complications. MATERIALS AND METHODS: A multicenter, five-year retrospective data analysis was conducted on hemodialysis patients with tunneled catheters. Patient data included age, gender, BMI, and associated comorbidities. The type of procedure (new tunnel insertion vs. exchange), exit site infection, and catheter-related bloodstream infection (CRBSI) were also included...
January 2024: Curēus
https://read.qxmd.com/read/38403649/prevalence-of-chronic-kidney-disease-in-tunisian-diabetics-the-tun-ckdd-survey
#34
JOURNAL ARTICLE
Jannet Labidi, Amel Harzallah, Badereddine Ben Kaab, Ikram Mami, Sahar Agrebi, Awatef Azzabi, Soumaya Chargui, Mayssa Hadj-Brahim, Mouna Hammouda, Saifeddine Azaiez, Syrine Tlili, Olfa Lajili, Hela Antit, Yosra Hasni, Sarra Chenik, Farhat Chelbi, Lamia Rais, Habib Skhiri
BACKGROUND: In Tunisia, the prevalence of diabetes mellitus increased from 15.5% on 2016 to 23% by 2023. While Chronic Kidney Disease (CKD) stills the most dreaded complications of diabetes, studies on the prevalence of chronic kidney disease non-dialysis diet are scarce. The aim of this study was to assess the prevalence of chronic kidney disease among the Tunisian diabetic population based on investigators' specialty, demographic criteria (gender, age, duration of diabetes and geographic distribution) and diagnosis criteria (albuminuria and/or eGFR)...
February 25, 2024: BMC Nephrology
https://read.qxmd.com/read/38402859/the-effect-of-positive-pressure-ventilation-on-acute-kidney-injury-in-covid-19-patients-with-acute-respiratory-distress-syndrome-an-observational-study
#35
JOURNAL ARTICLE
Lucia Zacchetti, Matteo Brivio, Mario Mezzapesa, Alessandra Martinelli, Veronica Punzi, Martina Monti, Federica Marchesi, Laura Scarpa, Rosalia Zangari, Luca Longhi, Federico Raimondi, Luca Novelli, Paolo Gritti, Lorenzo Grazioli, Gianluca Villa, Luca Lorini
INTRODUCTION: Acute kidney injury (AKI) is frequent in critically ill COVID-19 patients and is associated with a higher mortality risk. By increasing intrathoracic pressure, positive pressure ventilation (PPV) may reduce renal perfusion pressure by reducing venous return to the heart or by increasing renal venous congestion. This study's aim was to evaluate the association between AKI and hemodynamic and ventilatory parameters in COVID-19 patients with ARDS. METHODS: this is a single-centre retrospective observational study...
February 25, 2024: Blood Purification
https://read.qxmd.com/read/38400119/the-importance-of-natural-and-acquired-immunity-to-sars-cov-2-infection-in-patients-on-peritoneal-dialysis
#36
JOURNAL ARTICLE
Marko Baralić, Mirjana Laušević, Danica Ćujić, Ana Bontić, Jelena Pavlović, Voin Brković, Aleksandra Kezić, Kristina Mihajlovski, Lara Hadži Tanović, Iman Assi Milošević, Jovana Lukić, Marija Gnjatović, Aleksandra Todorović, Nikola M Stojanović, Dijana Jovanović, Milan Radović
The pandemic caused by the SARS-CoV-2 virus had a great impact on the population of patients treated with peritoneal dialysis (PD). This study demonstrates the impact of infection and vaccination in 66 patients treated with PD and their outcomes during a 6-month follow-up. This is the first research that has studied the dynamics of anti-SARS-CoV-2 IgG in serum and effluent. In our research, 57.6% of PD patients were vaccinated, predominantly with Sinopharm (81.6%), which was also the most frequently administered vaccine in the Republic of Serbia at the beginning of immunization...
January 29, 2024: Vaccines
https://read.qxmd.com/read/38396685/hyperparathyroidism-serum-phosphorus-and-dietary-intake-in-hemodialysis-patients-is-there-a-novel-relationship
#37
MULTICENTER STUDY
Cristina Garagarza, Ana Valente, Cátia Queirós, Inês Pastor Neto, Joana Sebastião, Melanie Gomes, Aníbal Ferreira
The management of hyperparathyroidism (intact parathyroid hormone (iPTH) serum levels > 585 pg/mL), frequently focuses on the appropriate control of mineral and bone markers, with the decrease in serum and dietary phosphorus as two of the targets. We aimed to investigate the association between iPTH, serum phosphorus levels and dietary intake. This was a cross-sectional, multicenter, observational study with 561 patients on hemodialysis treatment. Clinical parameters, body composition and dietary intake were assessed...
February 7, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38395340/outcome-of-open-repair-of-thoracoabdominal-aortic-aneurysm-in-takayasu-arteritis-a-retrospective-analysis
#38
JOURNAL ARTICLE
Neelamjingbha Sun, Ashutosh Kumar Pandey, Sriram Manchikanti, Aditya Gupta, Akash Rajeev, Sandeep Muniswamy, Prashant Jain, Prasanta Kuamr Dash, SreeKumar Ramachandran, Unnikrishnan Madathipat, Shivanesan Pitchai
OBJECTIVES: Takayasu Arteritis (TA) is an immune mediated arteritis causing inflammation of the aorta and its branches, which can result in aortic aneurysms. Our aim is to describe the outcome of surgical management in these patients who presented with Thoracoabdominal aortic aneurysm. METHODS: Between 2003 - 2023, 40 TA patients with thoracoabdominal aortic aneurysm (TAAA) underwent operative repair. RESULTS: There were 24 females and 16 males, in the age group of 19-53 years, with hypertension in 20 patients...
February 21, 2024: Annals of Vascular Surgery
https://read.qxmd.com/read/38390389/a-retrospective-cohort-study-of-clinical-characteristics-and-outcomes-of-type-2-diabetic-patients-with-kidney-disease
#39
JOURNAL ARTICLE
Xi He, Yuanjun Deng, Beichen Tian, Yixuan Zhao, Min Han, Yang Cai
BACKGROUND: Type 2 diabetes mellitus (T2DM) with chronic kidney disease (CKD) poses a serious health threat and becomes a new challenge. T2DM patients with CKD fall into three categories, diabetic nephropathy (DN), non-diabetic kidney disease (NDKD), and diabetic nephropathy plus non-diabetic kidney disease (DN + NDKD), according to kidney biopsy. The purpose of our study was to compare the clinical characteristics and kidney outcomes of DN, NDKD, and DN + NDKD patients. METHODS: Data on clinical characteristics, pathological findings, and prognosis were collected from June 2016 to July 2022 in patients with previously diagnosed T2DM and confirmed DN and or NDKD by kidney biopsy at Tongji Hospital in Wuhan, China...
2024: PeerJ
https://read.qxmd.com/read/38374615/lymphocele-outcomes-after-renal-transplantations-performed-by-an-experienced-surgeon-is-meticulously-performed-surgery-and%C3%A2-experience-adequate-to-prevent-lymphocele
#40
JOURNAL ARTICLE
Nurettin Ay, Vahhac Alp, Recai Duymuş, Sedat Çetin
BACKGROUND The purpose of the present study was to analyze the rate of lymphoceles in kidney transplant operations meticulously performed by the same senior surgeon. MATERIAL AND METHODS The present study included 315 patients who were operated on in our organ transplantation center and followed up in the polyclinic after July 2013. The patients were retrospectively divided into 2 groups: patients with and without lymphocele. Symptomatic lymphocele (SL) has been defined as symptomatic fluid collection around the graft that necessitates an intervention for the graft or patient...
February 20, 2024: Annals of Transplantation: Quarterly of the Polish Transplantation Society
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