keyword
Keywords ECMO, ECLS, Pediatric ECMO, Pe...

ECMO, ECLS, Pediatric ECMO, Pediatric intensive care

https://read.qxmd.com/read/36571494/single-center-experience-using-the-cardiohelp-system-for-neonatal-and-pediatric-extracorporeal-membrane-oxygenation
#21
JOURNAL ARTICLE
Nisha Agasthya, Curtis D Froehlich, Michael Golecki, Marisa Meyer, Mark T Ogino, Kendra Froehlich, Christopher Beaty, Sharon McCants, Timothy M Maul, Daniel R Dirnberger
OBJECTIVES: Extracorporeal membrane oxygenation (ECMO) systems have continued to evolve and improve with the development of smaller and portable systems. The Cardiohelp (Maquet Getinge Cardiopulmonary AG, Rastatt, Germany) portable life support device is a compact ECMO system used widely in adults and for ECMO transport. Reports of its use in neonatal and pediatric centers remain limited. In this single-center retrospective review, we describe our institutional experience with the Cardiohelp...
December 26, 2022: Pediatric Critical Care Medicine
https://read.qxmd.com/read/36516335/trends-in-neonatal-extracorporeal-membrane-oxygenation-during-a-venovenous-cannula-shortage
#22
JOURNAL ARTICLE
L Dupree Hatch, Brian C Bridges, Rachel L Chapman, Melissa E Danko, Robert E Schumacher, Stephen W Patrick
OBJECTIVES: To report temporal trends in venovenous extracorporeal membrane oxygenation (ECMO) use for neonatal respiratory failure in U.S. centers before and after functional venovenous cannula shortage due to withdrawal of one dual lumen venovenous cannula from the market in 2018. DESIGN: Retrospective cohort study. SETTING: ECMO registry of the Extracorporeal Life Support Organization. PATIENTS: Infants who received neonatal (cannulated prior to 29 d of age) respiratory ECMO at a U...
November 17, 2022: Pediatric Critical Care Medicine
https://read.qxmd.com/read/36453783/emergency-application-of-extracorporeal-membrane-oxygenation-in-a-pediatric-case-of-sudden-airway-collapse-due-to-anterior-mediastinal-mass-a-case-report-and-review-of-literature
#23
REVIEW
Muhterem Duyu, Zeynep Karakaya
Mediastinal masses can compress the respiratory or cardiovascular system, especially when anteriorly located. Obtaining histological material for diagnosis poses a challenge due to the major risk of cardiorespiratory collapse following anesthetic procedure. Our case shows the utility of rescue with venovenous extracorporeal membrane oxygenation (VV-ECMO) after occurrence of such an event and demonstrates the feasibility of administering chemotherapy during VV-ECMO. A 4-year-old boy was referred to the pediatric oncology clinic of our hospital after a large mediastinal mass was observed on chest radiography ordered due to persistent cough...
December 2022: Turkish Journal of Trauma & Emergency Surgery: TJTES
https://read.qxmd.com/read/36328821/associations-of-cephalad-drainage-in-neonatal-veno-venous-ecmo-a-mixed-effects-propensity-score-adjusted-retrospective-analysis-of-20-years-of-elso-data
#24
JOURNAL ARTICLE
Numa P Perez, Emily E Witt, Peter T Masiakos, Ilan Layman, Joseph E Tonna, Gezzer Ortega, Faisal G Qureshi
BACKGROUND: Neurologic complications can occur during neonatal Veno-Venous (VV) ECMO. The addition of a cephalad drainage cannula (i.e., VVDL+V) to dual lumen cannulation (i.e., VVDL) has been advocated to reduce such complications, but previous studies have presented mixed results. METHODS: Data from the ECMO Registry of the Extracorporeal Life Support Organization was used to extract all neonates (≤28 days old) who underwent VV ECMO for respiratory support between 2000 and 2019...
October 6, 2022: Journal of Pediatric Surgery
https://read.qxmd.com/read/36314958/interhospital-aircraft-ground-extracorporeal-membrane-oxygenation-transportation-by-a-mobile-extracorporeal-membrane-oxygenation-team-first-turkish-pediatric-case-series
#25
JOURNAL ARTICLE
Tanıl Kendirli, Fevzi Kahveci, Serhan Özcan, Edin Botan, Cahit Sarıcaoğlu, Ali İhsan Hasde, Mehmet Çakıcı, Tayfun Uçar, Zeynep Eyileten, Ercan Tutar, Ahmet Rüçhan Akar
OBJECTIVE: Extracorporeal membrane oxygenation is a life-saving treatment for patients with circulatory and respiratory failure refractory to standard therapy. However, safe and timely patient transport to the referral extracorporeal membrane oxygenation center is critical for better patient outcomes in patients with acute cardiogenic shock. This study aimed to describe children's features who were transferred to our center under extracorporeal membrane oxygenation by aircraft/ground vehicle and demonstrated the importance of extracorporeal cardiopulmonary resuscitation for transported children...
November 2022: Turkish archives of pediatrics
https://read.qxmd.com/read/36128776/prevalence-and-impact-of-infection-during-extracorporeal-membrane-oxygenation-in-oncologic-patients-a-retrospective-analysis-of-the-extracorporeal-life-support-organization-elso-registry
#26
JOURNAL ARTICLE
Yota Suzuki, Rui-Min D Mao, Nikhil R Shah, Lawrence Schaeffer, Abe Deanda, Ravi S Radhakrishnan
Background: Extracorporeal membrane oxygenation (ECMO) is widely utilized for severe cardiopulmonary insufficiency, but its application to the oncologic population has been debated given concern for increased risk of infection. This study aims to analyze the implications of infections acquired during ECMO runs in patients with malignancy. Methods: The Extracorporeal Life Support Organization (ELSO) database was queried for patients with an International Classification of Diseases code of neoplasms over the last two decades (2000-2019)...
September 21, 2022: Journal of Intensive Care Medicine
https://read.qxmd.com/read/36000833/extracorporeal-membrane-oxygenation-outcomes-in-children-with-preexisting-neurologic-disorders-or-neurofunctional-disability
#27
MULTICENTER STUDY
Siddhartha A Dante, Megan K Carroll, Derek K Ng, Ankur Patel, Philip C Spinella, Marie E Steiner, Laura L Loftis, Melania M Bembea
OBJECTIVE: Patient selection for pediatric extracorporeal membrane oxygenation (ECMO) support has broadened over the years to include children with pre-existing neurologic morbidities. We aimed to determine the prevalence and nature of pre-ECMO neurologic disorders or disability and investigate the association between pre-ECMO neurologic disorders or disability and mortality and unfavorable neurologic outcome. DESIGN: Multicenter retrospective observational cohort study...
November 1, 2022: Pediatric Critical Care Medicine
https://read.qxmd.com/read/35928331/eliminate-unnecessary-laboratory-work-to-mitigate-iatrogenic-anemia-and-reduce-cost-for-patients-on-extracorporeal-membrane-oxygenation
#28
JOURNAL ARTICLE
Maureen Welty, Beth Nachtsheim Bolick
Laboratory testing is a helpful tool for clinicians, but can be costly and harmful to patients. A quality improvement project was initiated to reduce laboratory testing for patients receiving extracorporeal membrane oxygenation (ECMO) in a pediatric intensive care unit (PICU) at a tertiary care center. Preliminary data was gathered to demonstrate preimplementation practice, cost, and patient need for packed red blood cell (pRBC) transfusions. A new protocol was created by an interprofessional team based on best practice and benchmarking with high-performing organizations...
June 2022: Journal of Extra-corporeal Technology
https://read.qxmd.com/read/35752606/spanish-society-of-intensive-and-critical-care-medicine-and-coronary-units-semicyuc-and-the-spanish-society-of-pediatric-intensive-care-secip-consensus-recommendations-for-ecmo-transport
#29
E Argudo, A Hernández-Tejedor, S Belda Hofheinz, M P Fuset, A Sanchez Galindo, P Burgueño, J Ballcels, J Duerto, A Morales Martínez, M Martínez-Martínez, E Morteruel Arizcuren, F Pérez, A Díaz Vico, J A Rubio Mateo-Sidrón
The evolution of extracorporeal membrane oxygenation treatment and the transport of patients receiving this treatment has changed dramatically in the last decade unevenly in different regions. The creation of specialized referral centers has been shown to improve outcomes. For all these reasons, it has been necessary to create networks of specialized teams and the number of secondary transports of patients with this treatment is increasing. In order to improve the quality of treatment and offer a guide to the services involved in these transports, the critical transport working groups of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) and the Spanish Society of Pediatric Intensive Care (SECIP) have carried out a joint effort to prepare these recommendations, focused on the following aspects: indications, reference center systems, means of transport, characteristics and equipment, human teams, training and clinical safety...
August 2022: Medicina intensiva
https://read.qxmd.com/read/35717646/life-threatening-complications-of-influenza-vs-coronavirus-disease-2019-covid-19-in-us-children
#30
JOURNAL ARTICLE
Natasha B Halasa, Andrew J Spieker, Cameron C Young, Samantha M Olson, Margaret M Newhams, Justin Z Amarin, Kristin L Moffitt, Mari M Nakamura, Emily R Levy, Vijaya L Soma, Rana Talj, Scott L Weiss, Julie C Fitzgerald, Elizabeth H Mack, Aline B Maddux, Jennifer E Schuster, Bria M Coates, Mark W Hall, Stephanie P Schwartz, Adam J Schwarz, Michele Kong, Philip C Spinella, Laura L Loftis, Gwenn E McLaughlin, Charlotte V Hobbs, Courtney M Rowan, Melania M Bembea, Ryan A Nofziger, Christopher J Babbitt, Cindy Bowens, Heidi R Flori, Shira J Gertz, Matt S Zinter, John S Giuliano, Janet R Hume, Natalie Z Cvijanovich, Aalok R Singh, Hillary A Crandall, Neal J Thomas, Melissa L Cullimore, Manish M Patel, Adrienne G Randolph
BACKGROUND: Clinical differences between critical illness from influenza infection vs coronavirus disease 2019 (COVID-19) have not been well characterized in pediatric patients. METHODS: We compared demographics, clinical characteristics, and outcomes of US children (aged 8 months to 17 years) admitted to the intensive care or high-acuity unit with influenza or COVID-19. Using mixed-effects models, we assessed the odds of death or requiring life support for influenza vs COVID-19 after adjustment for age, sex, race and Hispanic origin, and underlying conditions including obesity...
February 8, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/35664885/ethical-considerations-in-ever-expanding-utilization-of-ecls-a-research-agenda
#31
JOURNAL ARTICLE
Jonna D Clark, Harris P Baden, Emily R Berkman, Erica Bourget, Thomas V Brogan, Jane L Di Gennaro, Ardith Z Doorenbos, D Michael McMullan, Joan S Roberts, Jessica M Turnbull, Benjamin S Wilfond, Mithya Lewis-Newby
Technological advancements and rapid expansion in the clinical use of extracorporeal life support (ECLS) across all age ranges in the last decade, including during the COVID-19 pandemic, has led to important ethical considerations. As a costly and resource intensive therapy, ECLS is used emergently under high stakes circumstances where there is often prognostic uncertainty and risk for serious complications. To develop a research agenda to further characterize and address these ethical dilemmas, a working group of specialists in ECLS, critical care, cardiothoracic surgery, palliative care, and bioethics convened at a single pediatric academic institution over the course of 18 months...
2022: Frontiers in Pediatrics
https://read.qxmd.com/read/35330590/venovenous-extra-corporeal-life-support-in-an-infant-with-foreign-body-aspiration-a-case-report
#32
Ahmed S AlKhalifah, Nada A AlJassim
BACKGROUND: Foreign body aspiration (FBA) is a life-threatening emergency and a common cause of morbidity and morbidity in children. FBA can lead to rapidly progressive respiratory failure. Stabilizing patients after FBA for bronchoscopic removal of the aspirated object can be complex and may necessitate advanced support such as high-frequency oscillatory ventilation (HFOV) or extracorporeal membrane oxygenation (ECMO). This case report presents the feasibility of using ultrasound (US) in percutaneous catheterization in infants and the benefit of using venovenous ECMO (VV-ECMO) as rescue therapy in FBA...
2022: Respiratory Medicine Case Reports
https://read.qxmd.com/read/35321010/effect-of-platelet-transfusions-on-extracorporeal-life-support-oxygenator-s-function
#33
JOURNAL ARTICLE
Madhuradhar Chegondi, Niranjan Vijayakumar, Aditya Badheka, Oliver Karam
OBJECTIVE: Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO), leading to increased mortality. Since one of its main complications is bleeding, platelet transfusions are frequently prescribed for children on ECMO. However, there is currently very little information on the effect of platelet transfusions on the function of the ECMO oxygenator. Our objective was to describe the effect of platelet transfusions on oxygenator function. METHODS: In this retrospective study, we included all children (<18 years) who received ECMO support in our pediatric intensive care unit (PICU) between January 2017 and December 2019...
2022: Frontiers in Pediatrics
https://read.qxmd.com/read/35081085/tracheostomy-practices-and-outcomes-in-children-during-respiratory-extracorporeal-membrane-oxygenation
#34
JOURNAL ARTICLE
Joseph G Kohne, Graeme MacLaren, Erica Rider, Benjamin D Carr, Palen Mallory, Acham Gebremariam, Matthew L Friedman, Ryan P Barbaro
OBJECTIVES: Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however, the procedure carries risks, especially hemorrhagic complications. Knowledge of tracheostomy practices and outcomes of ECMO-supported children who undergo tracheostomy on ECMO may inform decision-making. DESIGN: Retrospective cohort study. SETTING: ECMO centers contributing to the Extracorporeal Life Support Organization registry...
April 1, 2022: Pediatric Critical Care Medicine
https://read.qxmd.com/read/35021004/effectiveness-of-bnt162b2-vaccine-against-critical-covid-19-in-adolescents
#35
MULTICENTER STUDY
Samantha M Olson, Margaret M Newhams, Natasha B Halasa, Ashley M Price, Julie A Boom, Leila C Sahni, Pia S Pannaraj, Katherine Irby, Tracie C Walker, Stephanie P Schwartz, Aline B Maddux, Elizabeth H Mack, Tamara T Bradford, Jennifer E Schuster, Ryan A Nofziger, Melissa A Cameron, Kathleen Chiotos, Melissa L Cullimore, Shira J Gertz, Emily R Levy, Michele Kong, Natalie Z Cvijanovich, Mary A Staat, Satoshi Kamidani, Brandon M Chatani, Samina S Bhumbra, Katherine E Bline, Mary G Gaspers, Charlotte V Hobbs, Sabrina M Heidemann, Mia Maamari, Heidi R Flori, Janet R Hume, Matt S Zinter, Kelly N Michelson, Laura D Zambrano, Angela P Campbell, Manish M Patel, Adrienne G Randolph
BACKGROUND: The increasing incidence of pediatric hospitalizations associated with coronavirus disease 2019 (Covid-19) caused by the B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States has offered an opportunity to assess the real-world effectiveness of the BNT162b2 messenger RNA vaccine in adolescents between 12 and 18 years of age. METHODS: We used a case-control, test-negative design to assess vaccine effectiveness against Covid-19 resulting in hospitalization, admission to an intensive care unit (ICU), the use of life-supporting interventions (mechanical ventilation, vasopressors, and extracorporeal membrane oxygenation), or death...
February 24, 2022: New England Journal of Medicine
https://read.qxmd.com/read/34995213/use-of-extracorporeal-membrane-oxygenation-in-acutely-poisoned-pediatric-patients-in-united-states-a-retrospective-analysis-of-the-extracorporeal-life-support-registry-from-2003-to-2019
#36
JOURNAL ARTICLE
Matteo Di Nardo, Danilo Alunni Fegatelli, Marco Marano, Jacob Danoff, Hong K Kim
OBJECTIVES: To describe the use of extracorporeal membrane oxygenation (ECMO) in the management of pediatric poisoning in the United States and to identify predictors of mortality. DESIGN: Retrospective cohort study. SETTING: Data reported to the Extracorporeal Life Support Organization by 76 U.S. ECMO centers from 2003 to 2019. PATIENTS: Pediatric patients (0-18 yr) receiving ECMO for poisoning. INTERVENTIONS: None...
April 1, 2022: Critical Care Medicine
https://read.qxmd.com/read/34895512/extracorporeal-membrane-oxygenation-in-children-receiving-haematopoietic-cell-transplantation-and-immune-effector-cell-therapy-an-international-and-multidisciplinary-consensus-statement
#37
REVIEW
Matteo Di Nardo, Ali H Ahmad, Pietro Merli, Matthew S Zinter, Leslie E Lehman, Courtney M Rowan, Marie E Steiner, Sangeeta Hingorani, Joseph R Angelo, Hisham Abdel-Azim, Sajad J Khazal, Basirat Shoberu, Jennifer McArthur, Rajinder Bajwa, Saad Ghafoor, Samir H Shah, Hitesh Sandhu, Karen Moody, Brandon D Brown, Maria E Mireles, Diana Steppan, Taylor Olson, Lakshmi Raman, Brian Bridges, Christine N Duncan, Sung Won Choi, Rita Swinford, Matt Paden, James D Fortenberry, Giles Peek, Pierre Tissieres, Daniele De Luca, Franco Locatelli, Selim Corbacioglu, Martin Kneyber, Alessio Franceschini, Simon Nadel, Matthias Kumpf, Alessandra Loreti, Roelie Wösten-Van Asperen, Orsola Gawronski, Joe Brierley, Graeme MacLaren, Kris M Mahadeo
Use of extracorporeal membrane oxygenation (ECMO) in children receiving haematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable advancements in HCT and immune effector cell therapies have changed expectations around reversibility of organ dysfunction and survival for affected patients. Herein, members of the Extracorporeal Life Support Organization (ELSO), Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network (HCT and cancer immunotherapy subgroup), the Pediatric Diseases Working Party of the European Society for Blood and Marrow Transplantation (EBMT), the supportive care committee of the Pediatric Transplantation and Cellular Therapy Consortium (PTCTC), and the Pediatric Intensive Care Oncology Kids in Europe Research (POKER) group of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) provide consensus recommendations on the use of ECMO in children receiving HCT and immune effector cell therapy...
February 2022: Lancet Child & Adolescent Health
https://read.qxmd.com/read/34715951/extracorporeal-membrane-oxygenation-the-first-10-years-experience-of-a-portuguese-pediatric-intensive-care-unit
#38
JOURNAL ARTICLE
Daniel Meireles, Francisco Abecasis, Leonor Boto, Cristina Camilo, Miguel Abecasis, José Pedro Neves, Zélia Cristo Soares, Marisa Vieira
INTRODUCTION: In Portugal, extracorporeal membrane oxygenation (ECMO) is used in pediatric patients since 2010. The aim of this study was to describe the clinical characteristics of patients, indications, complications and mortality associated with the use of ECMO during the first 10-years of experience in the Pediatric Intensive Care Unit located in Centro Hospitalar Universitário Lisboa Norte. MATERIAL AND METHODS: Retrospective observational cohort study of all patients supported with ECMO in a Pediatric Intensive Care Unit, from the 1st of May 2010 up to 31st December 2019...
June 1, 2021: Acta Médica Portuguesa
https://read.qxmd.com/read/34504424/optimized-dosing-regimens-of-meropenem-in-septic-children-receiving-extracorporeal-life-support
#39
JOURNAL ARTICLE
Yixue Wang, Weiming Chen, Yidie Huang, Guangfei Wang, Zhiping Li, Gangfeng Yan, Chao Chen, Guoping Lu
Objectives: To develop a population pharmacokinetic model of meropenem in children with sepsis receiving extracorporeal life support (ECLS) and optimize the dosage regimen based on investigating the probability of target attainment (PTA). Methods: The children with sepsis were prospectively enrolled in a pediatric intensive care unit from January 2018 to December 2019. The concentration-time data were fitted using nonlinear mixed effect model approach by NONMEM program. The stochastic simulation considering various scenarios based on proposed population pharmacokinetics model were conducted, and the PTAs were calculated to optimize the dosage regimens...
2021: Frontiers in Pharmacology
https://read.qxmd.com/read/34472993/outcomes-of-extracorporeal-membrane-oxygenation-and-cardiopulmonary-bypass-in-children-after-drowning-related-resuscitation
#40
JOURNAL ARTICLE
Urda Gottschalk, Maria Köhne, Theresa Holst, Ida Hüners, Maria von Stumm, Götz Müller, Veronika Stark, Victoria van Rüth, Rainer Kozlik-Feldmann, Dominique Singer, Jörg S Sachweh, Daniel Biermann
Drowning is one of the leading causes of accidental deaths in children worldwide. However, the use of long-term extracorporeal life support (ECLS) in this setting is not widely established, and rewarming is often achieved by short-term cardiopulmonary bypass (CPB) treatment. Thus, we sought to add our experience with this means of support as a bridge-to-recovery or to-decision. This retrospective single-center study analyzes the outcome of 11 children (median 23 months, minimum-maximum 3 months-6.5 years) who experienced drowning and subsequent cardiopulmonary resuscitation (CPR) between 2005 and 2016 and who were supported by veno-arterial extracorporeal membrane oxygenation (ECMO), CPB, or first CPB then ECMO...
September 2, 2021: Perfusion
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