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https://www.readbyqxmd.com/read/28544658/the-evolution-of-stories-from-mimesis-to-language-from-fact-to-fiction
#1
REVIEW
Brian Boyd
Why a species as successful as Homo sapiens should spend so much time in fiction, in telling one another stories that neither side believes, at first seems an evolutionary riddle. Because of the advantages of tracking and recombining true information, capacities for event comprehension, memory, imagination, and communication evolved in a range of animal species-yet even chimpanzees cannot communicate beyond the here and now. By Homo erectus, our forebears had reached an increasing dependence on one another, not least in sharing information in mimetic, prelinguistic ways...
May 24, 2017: Wiley Interdisciplinary Reviews. Cognitive Science
https://www.readbyqxmd.com/read/28537815/anticancer-treatments-and-female-fertility-clinical-concerns-and-role-of-oncologists-in-oncofertility-practice
#2
Mahmoud Salama, Teresa K Woodruff
Anticancer treatments such as aggressive chemotherapy and radiotherapy have deleterious gonadotoxic side effects and are considered the most common causes of pathological and iatrogenic fertility loss in women. Areas Covered: In order to preserve fertility of young women and girls with cancer, several established, experimental, and debatable options can be offered in the emerging field of oncofertility. This article reviews the effects of anticancer treatments on female fertility and discusses the current challenges and future directions of fertility preservation options that can be offered to the female patients with cancer...
May 24, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28536956/improving-functional-language-and-social-motivation-with-a-parent-mediated-intervention-for-toddlers-with-autism-spectrum-disorder
#3
Jessica Bradshaw, Lynn Kern Koegel, Robert L Koegel
Recent research suggests that children with autism spectrum disorder (ASD) may now be reliably identified in later infancy, highlighting the need for empirically-validated interventions for infants and toddlers with early symptoms of ASD. Using a multiple baseline design across 15- to 21-month-old toddlers, this study implemented a brief, parent-mediated, Pivotal Response Treatment program, focusing on improving expressive communication. The results indicated that verbal communication improved as a consequence of the intervention, with concomitant improvements in untreated areas for all participants...
May 23, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28535842/general-practitioners-clinical-expertise-in-managing-suicidal-young-people-implications-for-continued-education
#4
Maria Michail, Lynda Tait, Dick Churchill
Aim To examine general practitioners' (GPs) clinical expertise in assessing, communicating with, and managing suicidal young people aged 14-25 to inform the development of an educational intervention for GPs on youth suicide prevention. BACKGROUND: Suicide is the second leading cause of death for young people worldwide. GPs are ideally suited to facilitate early identification and assessment of suicide risk. However, GPs' levels of competence, knowledge, and attitudes towards suicidal young people have not yet been explored...
May 24, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28533516/asd-restricted-and-repetitive-behaviors-associated-at-17q21-33-genes-prioritized-by-expression-in-fetal-brains
#5
R M Cantor, L Navarro, H Won, R L Walker, J K Lowe, D H Geschwind
Autism spectrum disorder (ASD) is a behaviorally defined condition that manifests in infancy or early childhood as deficits in communication skills and social interactions. Often, restricted and repetitive behaviors (RRBs) accompany this disorder. ASD is polygenic and genetically complex, so we hypothesized that focusing analyses on intermediate core component phenotypes, such as RRBs, can reduce genetic heterogeneity and improve statistical power. Applying this approach, we mined Caucasian genome-wide association studies (GWAS) data from two of the largest ASD family cohorts, the Autism Genetics Resource Exchange and Autism Genome Project (AGP)...
May 23, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28532504/vineland-adaptive-behavior-scales-to-identify-neurodevelopmental-problems-in-children-with-congenital-hyperinsulinism-chi
#6
Maria Salomon-Estebanez, Zainab Mohamed, Maria Michaelidou, Hannah Collins, Lindsey Rigby, Mars Skae, Raja Padidela, Stewart Rust, Mark Dunne, Karen Cosgrove, Indraneel Banerjee, Jacqueline Nicholson
BACKGROUND: Congenital Hyperinsulinism (CHI) is a disease of severe hypoglycaemia caused by excess insulin secretion and associated with adverse neurodevelopment in a third of children. The Vineland Adaptive Behavior Scales Second Edition (VABS-II) is a parent report measure of adaptive functioning that could be used as a developmental screening tool in patients with CHI. We have investigated the performance of VABS-II as a screening tool to identify developmental delay in a relatively large cohort of children with CHI...
May 22, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28530514/public-understanding-of-the-purpose-of-cancer-screening-a-population-based-survey
#7
Amanda J Chorley, Yasemin Hirst, Charlotte Vrinten, Christian von Wagner, Jane Wardle, Jo Waller
Objectives In examining informed choice in cancer screening, we investigated public awareness that some screening programmes aim to prevent cancer, while others seek to detect cancer at an early stage. Methods A population-based survey of adults aged 50-70 in England (n = 1433), including data on demographic characteristics and screening experience. Participants were asked to select the main purpose of cervical, breast, and colorectal cancer screening (both faecal occult blood testing and flexible sigmoidoscopy)...
January 1, 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28524075/examining-the-overlap-between-autism-spectrum-disorder-and-22q11-2-deletion-syndrome
#8
Opal Ousley, A Nichole Evans, Samuel Fernandez-Carriba, Erica L Smearman, Kimberly Rockers, Michael J Morrier, David W Evans, Karlene Coleman, Joseph Cubells
22q11.2 deletion syndrome (22q11.2DS) is a genomic disorder reported to associate with autism spectrum disorders (ASDs) in 15-50% of cases; however, others suggest that individuals with 22q11.2DS present psychiatric or behavioral features associated with ASDs, but do not meet full criteria for ASD diagnoses. Such wide variability in findings may arise in part due to methodological differences across studies. Our study sought to determine whether individuals with 22q11.2DS meet strict ASD diagnostic criteria using research-based guidelines from the Collaborative Programs of Excellence in Autism (CPEA), which required a gathering of information from three sources: the Autism Diagnostic Interview-Revised (ADI-R), the Autism Diagnostic Observational Schedule (ADOS), and a clinician's best-estimate diagnosis...
May 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28523464/the-role-of-ontogeny-in-the-evolution-of-human-cooperation
#9
Michael Tomasello, Ivan Gonzalez-Cabrera
To explain the evolutionary emergence of uniquely human skills and motivations for cooperation, Tomasello et al. (2012, in Current Anthropology 53(6):673-92) proposed the interdependence hypothesis. The key adaptive context in this account was the obligate collaborative foraging of early human adults. Hawkes (2014, in Human Nature 25(1):28-48), following Hrdy (Mothers and Others, Harvard University Press, 2009), provided an alternative account for the emergence of uniquely human cooperative skills in which the key was early human infants' attempts to solicit care and attention from adults in a cooperative breeding context...
May 18, 2017: Human Nature: An Interdisciplinary Biosocial Perspective
https://www.readbyqxmd.com/read/28516347/uniting-the-pre-health-humanities-with-the-introductory-composition-course
#10
Amy Rubens
Drawing on my experiences at a teaching-focused university, I show how locating the health humanities in first-year or introductory composition courses improves learning and offers an economical, flexible, and far-reaching approach to bringing a health humanities education to all baccalaureate-level learners, regardless of whether they aspire to careers in the health professions. In terms of improving learning, health humanities composition courses support the disciplinary aims of both fields. Accessible, relevant issues in the health humanities, such as interventions in health debates or representations of illness and healthcare settings, nourish the cognitive and social conditions needed to develop college-level writing skills...
May 17, 2017: Journal of Medical Humanities
https://www.readbyqxmd.com/read/28511484/efficacy-of-structured-yoga-intervention-for-sleep-gastrointestinal-and-behaviour-problems-of-asd-children-an-exploratory-study
#11
Kumar Narasingharao, Balaram Pradhan, Janardhana Navaneetham
INTRODUCTION: Autism Spectrum Disorder (ASD) is a neuro developmental disorder which appears at early childhood age between 18 and 36 months. Apart from behaviour problems ASD children also suffer from sleep and Gastrointestinal (GI) problems. Major behaviour problems of ASD children are lack of social communication and interaction, less attention span, repetitive and restrictive behaviour, lack of eye to eye contact, aggressive and self-injurious behaviours, sensory integration problems, motor problems, deficiency in academic activities, anxiety and depression etc...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28507523/autism-spectrum-disorders-and-schizophrenia-spectrum-disorders-excitation-inhibition-imbalance-and-developmental-trajectories
#12
Roberto Canitano, Mauro Pallagrosi
Autism spectrum disorders (ASD) and schizophrenia spectrum disorders (SSD) share clinical and genetic components that have long been recognized. The two disorders co-occur more frequently than would be predicted by their respective prevalence, suggesting that a complex, multifactor association is involved. However, DSM-5 maintains the distinction between ASD, with core social and communication impairments, and SSD, including schizophrenia (SCZ), with hallucinations, delusions, and thought disorder as essential features...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28486934/progression-of-the-epidemiological-transition-in-a-rural-south-african-setting-findings-from-population-surveillance-in-agincourt-1993-2013
#13
Chodziwadziwa W Kabudula, Brian Houle, Mark A Collinson, Kathleen Kahn, Francesc Xavier Gómez-Olivé, Samuel J Clark, Stephen Tollman
BACKGROUND: Virtually all low- and middle-income countries are undergoing an epidemiological transition whose progression is more varied than experienced in high-income countries. Observed changes in mortality and disease patterns reveal that the transition in most low- and middle-income countries is characterized by reversals, partial changes and the simultaneous occurrence of different types of diseases of varying magnitude. Localized characterization of this shifting burden, frequently lacking, is essential to guide decentralised health and social systems on the effective targeting of limited resources...
May 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28480176/undiagnosed-diabetes-mellitus-and-related-factors-in-east-gojjam-nw-ethiopia-in-2016-a-community-based-study
#14
Amsalu Taye Wondemagegn, Habtamu Mellie Bizuayehu, Dagninet Derebe Abie, Getachew Mengistu Ayalneh, Tenaw Yimer Tiruye, Mequanint Taddele Tessema
INTRODUCTION: Currently, diabetes is the second most common non-communicable disease (NCD) in Ethiopia. Its burden is 4.8% in this country, even though three quarter of its population live with undiagnosed diabetes mellitus (DM), which causes complications like heart failure, blood vessels, eyes, kidneys and nerves damages. Early detection of DM is vital for a timely intervention to prevent these life threatening complications. The aim of this study was to assess the prevalence of undiagnosed DM and related factors in East Gojjam, North West Ethiopia, in 2016...
April 13, 2017: Journal of Public Health Research
https://www.readbyqxmd.com/read/28479121/ethical-considerations-and-palliative-care-in-patients-with-amyotrophic-lateral-sclerosis-a-review
#15
REVIEW
V Danel-Brunaud, L Touzet, L Chevalier, C Moreau, D Devos, S Vandolaeghe, L Defebvre
Amyotrophic lateral sclerosis (ALS) is not a curable disease, but it is treatable. By definition, much of the care provided to ALS patients is palliative, even though active life-sustaining strategies are available to prolong survival. Healthcare professionals must develop communication skills that help patients cope with the inexorable progression of the disease and the inevitability of death. Symptomatic treatments as well as respiratory insufficiency and nutritional life-sustaining therapies must be regularly evaluated as the disease progresses, without losing sight of the burden placed on the patient's non-professional caregivers...
May 4, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/28476685/association-study-of-the-vesicular-monoamine-transporter-1-vmat1-gene-with-autism-in-an-iranian-population
#16
Rezvan Noroozi, Soudeh Ghafouri-Fard, Mir Davood Omrani, Mohsen Habibi, Arezou Sayad, Mohammad Taheri
Autism Spectrum Disorders (ASD) (MIM 209850) are a group of neurodevelopmental disorders distinguished by destructed social interaction and communication abilities along with peculiar repetitive behavior. Several genetic loci have been linked to this disorder. Vesicular monoamine transporter 1 (VMAT1/SLC18A1) is an attractive candidate gene for psychiatric disorders because of its participation in regulation monoamines. In the present case-control study, we evaluated the link between three non-synonymous single nucleotide polymorphisms (SNPs) (rs2270641 [Pro4Thr], rs2270637 [Thr98Ser] and rs1390938 [Thr136Ile]) and one intronic SNP (rs2279709) across the VMAT1 gene and ASD in a group of Iranian patients...
May 2, 2017: Gene
https://www.readbyqxmd.com/read/28473308/sa%C3%A3%C2%BAde-na-copa-the-world-s-first-application-of-participatory-surveillance-for-a-mass-gathering-at-fifa-world-cup-2014-brazil
#17
Onicio Leal Neto, George Santiago Dimech, Marlo Libel, Wayner Vieira de Souza, Eduarda Cesse, Mark Smolinski, Wanderson Oliveira, Jones Albuquerque
BACKGROUND: The 2005 International Health Regulations (IHRs) established parameters for event assessments and notifications that may constitute public health emergencies of international concern. These requirements and parameters opened up space for the use of nonofficial mechanisms (such as websites, blogs, and social networks) and technological improvements of communication that can streamline the detection, monitoring, and response to health problems, and thus reduce damage caused by these problems...
May 4, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28471764/palliative-care-in-surgery-defining-the-research-priorities
#18
Elizabeth J Lilley, Zara Cooper, Margaret L Schwarze, Anne C Mosenthal
OBJECTIVE: To describe the existing science of palliative care in surgery within three priority areas and expose specific gaps within the field. BACKGROUND: Given the acute and often life-limiting nature of surgical illness, as well as the potential for treatment to induce further suffering, surgical patients have considerable palliative care needs. Yet these patients are less likely to receive palliative care than their medical counterparts and palliative care consultations often occur when death is imminent, reflecting poor quality end-of-life care...
May 3, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28464352/maternal-experience-raising-girls-with-autism-spectrum-disorder-a-qualitative-study
#19
N Navot, A G Jorgenson, S J Webb
BACKGROUND: A growing line of research has sought to characterize the different presentations of autism spectrum disorder (ASD) among boys and girls. Much less is known about maternal experience and mother-child relationship in children with ASD based on child gender. The present qualitative study aimed to investigate the mother-daughter relationship from the perspective of mothers who are raising girls with ASD with normal intelligence and functional verbal communication. METHODS: Eleven in-depth interviews were conducted with mothers of girls with ASD, ages 10-19 years...
May 2, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28457745/sensory-hypersensitivity-predicts-enhanced-attention-capture-by-faces-in-the-early-development-of-asd
#20
E J H Jones, G Dawson, S J Webb
Sensory sensitivity is prevalent among young children with ASD, but its relation to social communication impairment is unclear. Recently, increased sensory hypersensitivity has been linked to greater activity of the neural salience network (Green et al., 2016). Increased neural sensitivity to stimuli, especially social stimuli, could provide greater opportunity for social learning and improved outcomes. Consistent with this framework, in Experiment 1 we found that parent report of greater sensory hypersensitivity at 2 years in toddlers with ASD (N=27) was predictive of increased neural responsiveness to social stimuli (larger amplitude event-related potential/ERP responses to faces at P1, P400 and Nc) at 4 years, and this in turn was related to parent report of increased social approach at 4 years...
April 12, 2017: Developmental Cognitive Neuroscience
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