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https://www.readbyqxmd.com/read/28644796/design-of-an-autonomous-social-orienting-training-system-asots-for-young-children-with-autism
#1
Zhi Zheng, Qiang Fu, Huan Zhao, Amy R Swanson, Amy S Weitlauf, Zachary E Warren, Nilanjan Sarkar
Social communication is among the core areas of impairment for children with Autism Spectrum Disorders (ASD). The training of social orientation is important for improving social communication of children with ASD. In recent years, technology-assisted ASD intervention had gained momentum due to its potential advantages in terms of precision, sustainability, flexibility and cost. In this paper, we propose a closed-loop autonomous computer system, named ASOTS, for training social orientation skills to young children with ASD...
June 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28642217/an-interactive-mobile-based-tool-for-personal-social-network-data-collection-and-visualization-among-a-geographically-isolated-and-socioeconomically-disadvantaged-population-early-stage-feasibility-study-with-qualitative-user-feedback
#2
Katherine S Eddens, Jesse M Fagan, Tom Collins
BACKGROUND: Personal social networks have a profound impact on our health, yet collecting personal network data for use in health communication, behavior change, or translation and dissemination interventions has proved challenging. Recent advances in social network data collection software have reduced the burden of network studies on researchers and respondents alike, yet little testing has occurred to discover whether these methods are: (1) acceptable to a variety of target populations, including those who may have limited experience with technology or limited literacy; and (2) practical in the field, specifically in areas that are geographically and technologically disconnected, such as rural Appalachian Kentucky...
June 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28630806/prevalence-and-barriers-to-lung-cancer-screening-in-karachi-pakistan-a-cross-sectional-survey-of-smokers-and-physicians
#3
Aleeza Abbasi, Rabbia Siddiqi, Aatika Owais, Tooba Laeeq, Sara N Ali, Zonaira Mushahid, Syed M Ahsan, Aliya S Jatoi, Aleena Abbasi, Ifrah Butt, Ruba Ali, Maham Abbasi, Syeda Naintara N Jaffri, Mariam Jabir, Hajra Khanani, Kaneez Fatima
BACKGROUND: Early detection of lung cancer using low-dose computed tomography (LDCT) can potentially reduce morbidity and mortality. However, LDCT for lung cancer screening, especially in low income countries, has been underutilized. The objective of this study was to evaluate the prevalence and the potential personal, social, and economic barriers of lung cancer screening using LDCT. METHODS: A total sample of 156 smokers and 200 general physicians was collected during December 2016-February 2017 from community settings in Karachi, Pakistan...
May 15, 2017: Curēus
https://www.readbyqxmd.com/read/28624322/assessing-pragmatic-communication-in-children-with-down-syndrome
#4
Elizabeth Smith, Kari-Anne B Næss, Christopher Jarrold
PURPOSE: Successful communication depends on language content, language form, and language use (pragmatics). Children with Down syndrome (DS) experience communication difficulties, however little is known about their pragmatic profile, particularly during early school years. The purpose of the present study was to explore the nature of pragmatic communication in children with DS. METHOD: Twenty-nine six-year-old children with DS were assessed, in the areas of 1) initiation, 2) scripted language, 3) understanding context and 4) nonverbal communication, as reported by children's parents via the Children's Communication Checklist-2 (Bishop, 2003)...
June 9, 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28621001/early-vocabulary-development-in-children-with-bilateral-cochlear-implants
#5
Taina Välimaa, Sari Kunnari, Päivi Laukkanen-Nevala, Eila Lonka
BACKGROUND: Children with unilateral cochlear implants (CIs) may have delayed vocabulary development for an extended period after implantation. Bilateral cochlear implantation is reported to be associated with improved sound localization and enhanced speech perception in noise. This study proposed that bilateral implantation might also promote early vocabulary development. Knowledge regarding vocabulary growth and composition in children with bilateral CIs and factors associated with it may lead to improvements in the content of early speech and language intervention and family counselling...
June 16, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28620286/audience-effects-in-territorial-defense-of-male-cichlid-fish-are-associated-with-differential-patterns-of-activation-of-the-brain-social-decision-making-network
#6
António Roleira, Gonçalo A Oliveira, João S Lopes, Rui F Oliveira
Animals communicate by exchanging signals frequently in the proximity of other conspecifics that may detect and intercept signals not directed to them. There is evidence that the presence of these bystanders modulates the signaling behavior of interacting individuals, a phenomenon that has been named audience effect. Research on the audience effect has predominantly focused on its function rather than on its proximate mechanisms. Here, we have investigated the physiological and neuromolecular correlates of the audience effect in a cichlid fish (Mozambique tilapia, Oreochromis mossambicus)...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28618040/optimising-implementation-of-a-patient-assessment-framework-for-emergency-nurses-a-mixed-method-study
#7
Belinda Munroe, Kate Curtis, Thomas Buckley, Melinda Lewis, Lou Atkins
AIMS AND OBJECTIVES: To determine potential facilitators and barriers and tailor interventions to optimise future implementation of a patient-assessment framework into emergency nursing practice. BACKGROUND: An evidence-informed patient-assessment framework HIRAID (History, Identify Red flags, Assessment, Interventions, Diagnostics, communication and reassessment) improves the quality of patient assessments performed by emergency nurses. Facilitators and barriers must be understood and tailored interventions selected to optimise implementation...
June 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28612953/eye-movements-sensori-motor-adaptation-and-cerebellar-dependent-learning-in-autism-towards-potential-biomarkers-and-sub-phenotypes
#8
Edward G Freedman, John J Foxe
Because of the wide range of symptoms expressed in individuals with Autism Spectrum Disorder (ASD) and their idiosyncratic severity it is unlikely that a single remedial approach will be universally effective. Resolution of this dilemma requires identifying subgroups within the autism spectrum, based on symptom set and severity, on an underlying neuro-structural difference, and on specific behavioral dysfunction. This will provide critical insight into the disorder and may lead to better diagnoses, and more targeted remediation in these subphenotypes of people with ASD...
June 14, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28609458/dendritic-overgrowth-and-elevated-erk-signaling-during-neonatal-development-in-a-mouse-model-of-autism
#9
Ning Cheng, Fawaz Alshammari, Elizabeth Hughes, Maryam Khanbabaei, Jong M Rho
Autism spectrum disorder (hereafter referred to as "ASD") is a heterogeneous neurodevelopmental condition characterized by impaired social communication and interactions, and restricted, repetitive activities or interests. Alterations in network connectivity and memory function are frequently observed in autism patients, often involving the hippocampus. However, specific changes during early brain development leading to disrupted functioning remain largely unclear. Here, we investigated the development of dendritic arbor of hippocampal CA1 pyramidal neurons in the BTBR T+tf/J (BTBR) mouse model of autism...
2017: PloS One
https://www.readbyqxmd.com/read/28599002/social-orienting-and-joint-attention-in-preschoolers-with-autism-spectrum-disorders
#10
Martina Franchini, Bronwyn Glaser, Hilary Wood de Wilde, Edouard Gentaz, Stephan Eliez, Marie Schaer
Children with Autism Spectrum Disorders (ASD) orient less to socially salient stimuli, such as dynamic social images, than typically developing children. In turn, this lack of social orienting is thought to impair affected individuals' socio communicative development. Here, we aim to explore the relationship between time spent on dynamic social images and ASD behaviors, such as joint attention and communication, in preschoolers on the autism spectrum. In this study, social orienting is measured using eye-tracking during a task consisting of side-by-side presentations of dynamic social images and dynamic geometric images...
2017: PloS One
https://www.readbyqxmd.com/read/28598503/children-s-early-awareness-of-comprehension-as-evident-in-their-spontaneous-corrections-of-speech-errors
#11
Henry M Wellman, Ju-Hyun Song, Hope Peskin-Shepherd
A crucial human cognitive goal is to understand and to be understood. But understanding often takes active management. Two studies investigated early developmental processes of understanding management by focusing on young children's comprehension monitoring. We ask: When and how do young children actively monitor their comprehension of social-communicative interchanges and so seek to clarify and correct their own potential miscomprehension? Study 1 examined the parent-child conversations of 13 children studied longitudinally in everyday situations from the time the children were approximately 2 years through 3 years...
June 9, 2017: Child Development
https://www.readbyqxmd.com/read/28590057/behavioral-abnormalities-in-the-fmr1-ko2-mouse-model-of-fragile-x-syndrome-the-relevance-of-early-life-phases
#12
Julie Gaudissard, Melanie Ginger, Marika Premoli, Maurizio Memo, Andreas Frick, Susanna Pietropaolo
Fragile X syndrome (FXS) is a developmental disorder caused by a mutation in the X-linked FMR1 gene, coding for the FMRP protein which is largely involved in synaptic function. FXS patients present several behavioral abnormalities, including hyperactivity, anxiety, sensory hyper-responsiveness, and cognitive deficits. Autistic symptoms, e.g., altered social interaction and communication, are also often observed: FXS is indeed the most common monogenic cause of autism. Mouse models of FXS are therefore of great interest for research on both FXS and autistic pathologies...
June 7, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28581333/relations-of-early-motor-skills-on-age-and-socialization-communication-and-daily-living-in-young-children-with-developmental-disabilities
#13
Megan MacDonald, Samantha Ross, Laura Lee McIntyre, Amanda Tepfer
Young children with developmental disabilities experience known deficits in salient child behaviors, such as social behaviors, communication, and aspects of daily living, behaviors that generally improve with chronological age. The purpose of this study was to examine the mediating effects of motor skills on relations of age and salient child behaviors in a group of young children with developmental disabilities, thus tapping into the potential influences of motor skills in the development of salient child behaviors...
April 2017: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/28577609/the-early-origins-of-autism
#14
REVIEW
John N Constantino, Natasha Marrus
Autism spectrum disorders (ASDs) are neurodevelopmental disorders whose core features of impaired social communication and atypical repetitive behaviors and/or restrictions in range of interests emerge in toddlerhood and carry significant implications at successive stages of development. The ability to reliably identify most cases of the condition far earlier than the average age of diagnosis presents a novel opportunity for early intervention, but the availability of such an intervention is disparate across US communities, and its impact is imperfectly understood...
July 2017: Child and Adolescent Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/28575768/early-life-status-epilepticus-acutely-impacts-select-quantitative-and-qualitative-features-of-neonatal-vocalization-behavior-spectrographic-and-temporal-characterizations-in-c57bl-6-mice
#15
Conner D Reynolds, Suzanne O Nolan, Jessica L Huebschman, Samantha L Hodges, Joaquin N Lugo
Early-life seizures are known to cause long-term deficits in social behavior, learning, and memory, however little is known regarding their acute impact. Ultrasonic vocalization (USV) recordings have been developed as a tool for investigating early communicative deficits in mice. Previous investigation from our lab found that postnatal day (PD) 10 seizures cause male-specific suppression of 50-kHz USVs on PD12 in 129 SvEvTac mouse pups. The present study extends these findings by spectrographic characterization of USVs following neonatal seizures...
May 30, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28574442/electrophysiological-indices-of-audiovisual-speech-perception-in-the-broader-autism-phenotype
#16
Julia Irwin, Trey Avery, Jacqueline Turcios, Lawrence Brancazio, Barbara Cook, Nicole Landi
When a speaker talks, the consequences of this can both be heard (audio) and seen (visual). A novel visual phonemic restoration task was used to assess behavioral discrimination and neural signatures (event-related potentials, or ERP) of audiovisual processing in typically developing children with a range of social and communicative skills assessed using the social responsiveness scale, a measure of traits associated with autism. An auditory oddball design presented two types of stimuli to the listener, a clear exemplar of an auditory consonant-vowel syllable /ba/ (the more frequently occurring standard stimulus), and a syllable in which the auditory cues for the consonant were substantially weakened, creating a stimulus which is more like /a/ (the infrequently presented deviant stimulus)...
June 2, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28566999/communication-impairment-in-ultrasonic-vocal-repertoire-during-the-suckling-period-of-cd157-knockout-mice-transient-improvement-by-oxytocin
#17
Olga L Lopatina, Kazumi Furuhara, Katsuhiko Ishihara, Alla B Salmina, Haruhiro Higashida
Communication consists of social interaction, recognition, and information transmission. Communication ability is the most affected component in children with autism spectrum disorder (ASD). Recently, we reported that the CD157/BST1 gene is associated with ASD, and that CD157 knockout (Cd157(-/-)) mice display severe impairments in social behavior that are improved by oxytocin (OXT) treatment. Here, we sought to determine whether Cd157(-/-) mice can be used as a suitable model for communication deficits by measuring ultrasonic vocalizations (USVs), especially in the early developmental stage...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28544658/the-evolution-of-stories-from-mimesis-to-language-from-fact-to-fiction
#18
REVIEW
Brian Boyd
Why a species as successful as Homo sapiens should spend so much time in fiction, in telling one another stories that neither side believes, at first seems an evolutionary riddle. Because of the advantages of tracking and recombining true information, capacities for event comprehension, memory, imagination, and communication evolved in a range of animal species-yet even chimpanzees cannot communicate beyond the here and now. By Homo erectus, our forebears had reached an increasing dependence on one another, not least in sharing information in mimetic, prelinguistic ways...
May 24, 2017: Wiley Interdisciplinary Reviews. Cognitive Science
https://www.readbyqxmd.com/read/28537815/anticancer-treatments-and-female-fertility-clinical-concerns-and-role-of-oncologists-in-oncofertility-practice
#19
Mahmoud Salama, Teresa K Woodruff
Anticancer treatments such as aggressive chemotherapy and radiotherapy have deleterious gonadotoxic side effects and are considered the most common causes of pathological and iatrogenic fertility loss in women. Areas covered: In order to preserve fertility of young women and girls with cancer, several established, experimental, and debatable options can be offered in the emerging field of oncofertility. This article reviews the effects of anticancer treatments on female fertility and discusses the current challenges and future directions of fertility preservation options that can be offered to the female patients with cancer...
June 5, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28536956/improving-functional-language-and-social-motivation-with-a-parent-mediated-intervention-for-toddlers-with-autism-spectrum-disorder
#20
Jessica Bradshaw, Lynn Kern Koegel, Robert L Koegel
Recent research suggests that children with autism spectrum disorder (ASD) may now be reliably identified in later infancy, highlighting the need for empirically-validated interventions for infants and toddlers with early symptoms of ASD. Using a multiple baseline design across 15- to 21-month-old toddlers, this study implemented a brief, parent-mediated, Pivotal Response Treatment program, focusing on improving expressive communication. The results indicated that verbal communication improved as a consequence of the intervention, with concomitant improvements in untreated areas for all participants...
May 23, 2017: Journal of Autism and Developmental Disorders
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