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https://www.readbyqxmd.com/read/29785898/accuracy-and-application-of-milk-fatty-acid-estimation-with-diffuse-reflectance-near-infrared-spectroscopy
#1
Andreas Melfsen, Max Holstermann, Angelika Haeussermann, Joachim Molkentin, Andreas Susenbeth, Eberhard Hartung
Near infrared spectroscopy (NIRS) has the potential to estimate contents of fatty acids (FA) in milk frequently at-farm or during daily milking routine. In this study, a total of 738 raw milk spectra collected from 33 Holstein cows over a period of 30 weeks were recorded. Reference data on FA composition in milk and in milk fat were analysed in laboratory. Calibration models were calculated for single FA and groups of FA in milk and in milk fat. Validation resulted in sufficient Ratio of Prediction to Deviation (RPD) values for some single FA and in higher RPD values for groups of FA when concentrations of FA in milk were predicted...
May 2018: Journal of Dairy Research
https://www.readbyqxmd.com/read/29783751/targeting-protein-quality-control-mechanisms-by-natural-products-to-promote-healthy-ageing
#2
REVIEW
Sophia Wedel, Maria Manola, Maria Cavinato, Ioannis P Trougakos, Pidder Jansen-Dürr
Organismal ageing is associated with increased chance of morbidity or mortality and it is driven by diverse molecular pathways that are affected by both environmental and genetic factors. The progression of ageing correlates with the gradual accumulation of stressors and damaged biomolecules due to the time-dependent decline of stress resistance and functional capacity, which eventually compromise cellular homeodynamics. As protein machines carry out the majority of cellular functions, proteome quality control is critical for cellular functionality and is carried out through the curating activity of the proteostasis network (PN)...
May 19, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29780699/moving-beyond-normative-philosophies-and-policy-concerns-a-sociological-account-of-place-based-solidarities-in-diversity
#3
Stijn Oosterlynck
In this commentary, I think with and beyond the normative philosophies and policy-oriented frameworks on how to deal with diversity in contemporary societies formulated by Zapata-Barrero and Modood. I propose to integrate elements of both perspectives in a empirically grounded sociological account of how place-based solidarities in diversity are nurtured in everyday life. Although there is much to be recommended about the arguments of Modood and Zapata-Barrero, I argue that what is needed is an analytical framework that does not a priori privilege specific sources of solidarity on normative-philosophical or policy grounds...
2018: Comparative Migration Studies
https://www.readbyqxmd.com/read/29777454/improved-outcomes-in-394-pancreatic-cancer-resections-the-impact-of-enhanced-recovery-pathway
#4
Vandana Agarwal, Martin Jose Thomas, Riddhi Joshi, Vikram Chaudhari, Manish Bhandare, Abhishek Mitra, Ashwin deSouza, Reshma Ambulkar, Shailesh V Shrikhande
BACKGROUND: Enhanced recovery (ER) pathway reduces morbidity and accelerates recovery. It is associated with reduced postoperative stay, morbidity, and costs. Feasibility and safety of ER programme has not been studied in developing countries. The objectives were to assess compliance with Enhanced Recovery After Surgery (ERAS) elements and to assess outcomes in pancreatic surgery. METHODS: Prospective study conducted from February 2014 to December 2016, following elective pancreatic cancer surgery...
May 18, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29770560/how-nurses-restore-and-maintain-mobility-in-hospitalised-older-people-an-integrative-literature-review
#5
Stephanie Constantin, Sherry Dahlke
AIM: The aim of this integrative review of the literature was to evaluate and summarise current research about how nurses maintain and improve hospitalised older peoples' mobility levels. BACKGROUND: Older persons make up the majority of healthcare recipients, and they are at risk to experience significant decline in their mobility once hospitalised. This can result in longer hospitalisations or nursing home admissions. Currently, it is not well understood how nurses maintain and restore mobility of hospitalised older persons...
May 17, 2018: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/29764257/collaboration-in-the-design-and-delivery-of-a-mental-health-recovery-college-course-experiences-of-students-and-tutors
#6
Josh Cameron, Angie Hart, Saff Brooker, Paul Neale, Mair Reardon
BACKGROUND: Recovery Colleges address mental health challenges using an educative approach underpinned by a collaborative recovery orientated philosophy. Research has been limited with no studies identified reporting research on the design and delivery of a specific course. AIMS: To understand how Recovery College students and tutors experience the design and delivery of a mental health Recovery College course, specifically the "'Building Resilience" course...
May 15, 2018: Journal of Mental Health
https://www.readbyqxmd.com/read/29763678/acute-aerobic-exercise-induces-a-preferential-mobilisation-of-plasmacytoid-dendritic-cells-into-the-peripheral-blood-in-man
#7
Frankie F Brown, John P Campbell, Alex J Wadley, James P Fisher, Sarah Aldred, James E Turner
Dendritic cells (DCs) are important sentinel cells of the immune system responsible for presenting antigen to T cells. Exercise is known to cause an acute and transient increase in the frequency of DCs in the bloodstream in humans, yet there are contradictory findings in the literature regarding the phenotypic composition of DCs mobilised during exercise, which may have implications for immune regulation and health. Accordingly, we sought to investigate the composition of DC sub-populations mobilised in response to acute aerobic exercise...
May 12, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29760878/chiropractic-treatment-including-instrument-assisted-manipulation-for-non-specific-dizziness-and-neck-pain-in-community-dwelling-older-people-a-feasibility-randomised-sham-controlled-trial
#8
Julie C Kendall, Simon D French, Jan Hartvigsen, Michael F Azari
Background: Dizziness in older people is a risk factor for falls. Neck pain is associated with dizziness and responds favourably to neck manipulation. However, it is unknown if chiropractic intervention including instrument-assisted manipulation of the neck in older people with neck pain can also improve dizziness. Methods: This parallel two-arm pilot trial was conducted in Melbourne, Australia over nine months (October 2015 to June 2016). Participants aged 65-85 years, with self-reported chronic neck pain and dizziness, were recruited from the general public through advertisements in local community newspapers and via Facebook...
2018: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/29758071/the-long-term-impact-of-community-mobilisation-through-participatory-women-s-groups-on-women-s-agency-in-the-household-a-follow-up-study-to-the-makwanpur-trial
#9
Lu Gram, Jolene Skordis-Worrall, Dharma S Manandhar, Daniel Strachan, Joanna Morrison, Naomi Saville, David Osrin, Kirti M Tumbahangphe, Anthony Costello, Michelle Heys
Women's groups practicing participatory learning and action (PLA) in rural areas have been shown to improve maternal and newborn survival in low-income countries, but the pathways from intervention to impact remain unclear. We assessed the long-term impact of a PLA intervention in rural Nepal on women's agency in the household. In 2014, we conducted a follow-up study to a cluster randomised controlled trial on the impact of PLA women's groups from 2001-2003. Agency was measured using the Relative Autonomy Index (RAI) and its subdomains...
2018: PloS One
https://www.readbyqxmd.com/read/29751754/examining-diffusion-to-understand-the-how-of-sasa-a-violence-against-women-and-hiv-prevention-intervention-in-uganda
#10
Elizabeth Starmann, Lori Heise, Nambusi Kyegombe, Karen Devries, Tanya Abramsky, Lori Michau, Tina Musuya, Charlotte Watts, Martine Collumbien
BACKGROUND: A growing number of complex public health interventions combine mass media with community-based "change agents" and/or mobilisation efforts acting at multiple levels. While impact evaluations are important, there is a paucity of research into the more nuanced roles intervention and social network factors may play in achieving intervention outcomes, making it difficult to understand how different aspects of the intervention worked (or did not). This study applied aspects of diffusion of innovations theory to explore how SASA!, a community mobilisation approach for preventing HIV and violence against women, diffused within intervention communities and the factors that influenced the uptake of new ideas and behaviours around intimate partner relationships and violence...
May 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29748138/defining-new-barriers-to-mobilisation-in-a-highly-active-intensive-care-unit-have-we-found-the-ceiling-an-observational-study
#11
Christopher Brock, Vince Marzano, Margot Green, Jiali Wang, Teresa Neeman, Imogen Mitchell, Bernie Bissett
BACKGROUND: Mobilisation of intensive care (ICU) patients attenuates ICU-acquired weakness, but the prevalence is low (12-54%). Better understanding of barriers and enablers may inform practice. OBJECTIVES: To identify barriers to mobilisation and factors associated with successful mobilisation in our medical /surgical /trauma ICU where mobilisation is well-established. METHODS: 4-week prospective study of frequency and intensity of mobilisation, clinical factors and barriers (extracted from electronic database)...
May 7, 2018: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/29744945/understanding-the-development-of-a-regulated-market-approach-to-new-psychoactive-substances-nps-in-new-zealand-using-punctuated-equilibrium-theory
#12
Marta Rychert, Chris Wilkins
BACKGROUND AND AIMS: The short-lived regulated legal market for new psychoactive substances (NPS) in New Zealand marked a radical departure from the traditional prohibition-based approach. This paper aimed to enhance understanding of this policy change using Punctuated Equilibrium Theory (PET). METHODS: The analysis draws on three years of evaluative research, including interviews with key stakeholders, analysis of legislation and policy documents and academic and grey literature...
May 9, 2018: Addiction
https://www.readbyqxmd.com/read/29739369/increasing-advance-personal-planning-the-need-for-action-at-the-community-level
#13
Amy Waller, Rob Sanson-Fisher, Nola Ries, Jamie Bryant
BACKGROUND: Advance personal planning is the process by which people consider, document and communicate their preferences for personal, financial and health matters in case they lose the ability to make decisions or express their wishes in the future. DISCUSSION: Advance personal planning is most often undertaken by individuals who are seriously ill, often in the context of a medical crisis and/or at the time of admission to hospital. However, the clinical utility and legal validity of the planning process may be compromised in these circumstances...
May 9, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29736141/isolation-and-sequence-analysis-of-pcs36-4cpa-a-small-plasmid-from-citrobacter-sp-36-4cpa
#14
Natalia V Zharikova, Timur R Iasakov, Boris K Bumazhkin, Ekaterina O Patutina, Evgeniia I Zhurenko, Vladislav V Korobov, Alina I Sagitova, Boris B Kuznetsov, Tatiana V Markusheva
A small plasmid designated pCS36-4CPA with a size of 5217 base pairs and G-C content of 50.74% was isolated from Citrobacter sp. 36-4CPA. The origin of replication ( ori ) of the plasmid was identified as a region of about 800 bp in length with an identity of 67.1% to the ColE1 plasmid at the nucleotide level. The replication region contained typical elements of ColE1-like plasmids: RNA I and RNA II with their corresponding -10 and -35 boxes, a single-strand initiation site ( ssi ), and a lagging-strand termination site ( terH )...
May 2018: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/29728139/bottlenecks-concerns-and-needs-in-malaria-operational-research-the-perspectives-of-key-stakeholders-in-nigeria
#15
Pamela Onyiah, Al-Mukhtar Y Adamu, Rotimi F Afolabi, Olufemi Ajumobi, Maduka D Ughasoro, Oluwaseun Odeyinka, Patrick Nguku, IkeOluwapo O Ajayi
OBJECTIVE: We conducted a study to determine stakeholders' perspective of the bottlenecks, concerns and needs to malaria operational research (MOR) agenda setting in Nigeria. RESULTS: Eighty-five (37.9%) stakeholders identified lack of positive behavioural change as the major bottleneck to MOR across the malaria thematic areas comprising of malaria prevention 58.8% (50), case management 34.8% (39), advocacy communication and social mobilisation 4.7% (4) while procurement and supply chain management (PSM) and programme management experts had the least response of 1...
May 4, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29726286/risk-of-subsidence-and-peri-prosthetic-fractures-using-collared-hydroxyapatite-coated-stem-for-hip-arthroplasty-in-the-elderly
#16
Farhan Syed, Amr Hussein, Krishnaiah Katam, Paul Saunders, Stephen K Young, Mohammad Faisal
INTRODUCTION: Subsidence has been noted with both cemented and uncemented stems in hip arthroplasty. On most occasions, it's minimal (i.e. less than 2 mm) and stabilises at 1 year. However, when its progressive and significant, it causes loss of length and horizontal offset, and when symptomatic warrants a revision. Patients/Materials & Methods: A retrospective radiological review of the patient database was carried out to identify all patients with age ≥ 70 years who underwent elective hip arthroplasty using uncemented HA coated collared stem and had radiographs at 1 year follow up...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29725986/efficacy-and-safety-of-analgesic-treatment-for-depression-in-people-with-advanced-dementia-randomised-multicentre-double-blind-placebo-controlled-trial-dep-pain-dem
#17
Ane Erdal, Elisabeth Flo, Dag Aarsland, Clive Ballard, Dagrun D Slettebo, Bettina S Husebo
BACKGROUND: Chronic pain and depression often co-occur, and pain may exacerbate depression in people with dementia. OBJECTIVE: The objective of this study was to assess the efficacy and safety of analgesic treatment for depression in nursing home patients with advanced dementia and clinically significant depressive symptoms. METHODS: We conducted a multicentre, parallel-group, double-blind, placebo-controlled trial in 47 nursing homes, including 162 nursing home patients aged ≥ 60 years with dementia (Mini-Mental State Examination ≤ 20) and depression (Cornell Scale for Depression in Dementia ≥ 8)...
May 3, 2018: Drugs & Aging
https://www.readbyqxmd.com/read/29725511/outcome-of-primary-cemented-bipolar-hemiarthroplasty-compared-with-dynamic-hip-screw-in-elderly-patients-with-unstable-intertrochanteric-fracture
#18
Y N Gashi, A S Elhadi, I M Elbushra
Introduction: Although the treatment of choice for unstable intertrochanteric fractures in elderly patients has been internal fixation for a long time, several studies have shown mechanical and technical failures. Primary cemented bipolar (PCB) hemiarthroplasty has been proposed as an alternative with some advantages concerning earlier mobilization and minimal postoperative complications. Materials and Methods: This is a prospective cohort hospital-based study conducted at three tertiary hospitals over a period of two years...
March 2018: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29721607/hydrogen-sulphide-facilitates-exocytosis-by-regulating-the-handling-of-intracellular-calcium-by-chromaffin-cells
#19
Ricardo de Pascual, Andrés M Baraibar, Iago Méndez-López, Martín Pérez-Ciria, Ignacio Polo-Vaquero, Luis Gandía, Sunny E Ohia, Antonio G García, Antonio M G de Diego
Gasotransmitter hydrogen sulphide (H2 S) has emerged as a regulator of multiple physiological and pathophysiological processes throughout. Here, we have investigated the effects of NaHS (fast donor of H2 S) and GYY4137 (GYY, slow donor of H2 S) on the exocytotic release of catecholamines from fast-perifused bovine adrenal chromaffin cells (BCCs) challenged with sequential intermittent pulses of a K+ -depolarizing solution. Both donors caused a concentration-dependent facilitation of secretion. This was not due to an augmentation of Ca2+ entry through voltage-activated Ca2+ channels (VACCs) because, in fact, NaHS and GYY caused a mild inhibition of whole-cell Ca2+ currents...
May 2, 2018: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/29720616/author-correction-endogenous-annexin-a1-regulates-haematopoietic-stem-cell-mobilisation-and-inflammatory-response-post-myocardial-infarction-in-mice-in-vivo
#20
Cheng Xue Qin, Siobhan B Finlayson, Annas Al-Sharea, Mitchel Tate, Miles J De Blasio, Minh Deo, Sarah Rosli, Darnel Prakoso, Colleen J Thomas, Helen Kiriazis, Eleanor Gould, Yuan H Yang, Eric F Morand, Mauro Perretti, Andrew J Murphy, Xiao-Jun Du, Xiao-Ming Gao, Rebecca H Ritchie
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
May 2, 2018: Scientific Reports
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