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https://www.readbyqxmd.com/read/28089812/clinical-manifestations-and-outcomes-in-surgically-managed-gartner-duct-cysts-1
#1
Adela G Cope, Shannon Laughlin-Tommaso, Abimbola Famuyide, John B Gebhart, Matthew R Hopkins, Daniel M Breitkopf
STUDY OBJECTIVE: Gartner duct cysts (GDC) are rare embryological remnants of the mesonephric duct with the majority of cases discovered incidentally in asymptomatic patients. The largest prior published series evaluating surgical management of GDC included 4 patients. The present study aims to determine the manifestations and outcomes of surgically managed patients with GDC with important implications for surveillance, monitoring, and management of patients. DESIGN: Retrospective chart review DESIGN: Classification: Canadian Task Force Classification III SETTING: Tertiary care center PATIENTS: All women diagnosed with GDC from 1/1994-4/2014 at our institution were identified...
January 12, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28087185/the-filum-terminale-internum-and-externum-a-comprehensive-review
#2
REVIEW
Erfanul Saker, Brandon M Henry, Krzysztof A Tomaszewski, Marios Loukas, Joe Iwanaga, Rod J Oskouian, R Shane Tubbs
INTRODUCTION: The filum terminale has oven been overlooked in the literature probably due to its small size and historical lack of research on its true morphology. However, this structure's roll in the tethered cord syndrome has become more apparent. Therefore, the current comprehensive review seemed timely. METHODS: Using standard search engines, the history, embryology, anatomy, pathology and surgery of the filum terminale were reviewed. CONCLUSIONS: It is only recently that the true anatomy and pathological involvement of the filum terminale in the tethered cord syndrome have been elucidated...
January 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28081151/human-lacrimal-gland-gene-expression
#3
Vinay Kumar Aakalu, Sowmya Parameswaran, Mark Maienschein-Cline, Neil Bahroos, Dhara Shah, Marwan Ali, Subramanian Krishnakumar
BACKGROUND: The study of human lacrimal gland biology and development is limited. Lacrimal gland tissue is damaged or poorly functional in a number of disease states including dry eye disease. Development of cell based therapies for lacrimal gland diseases requires a better understanding of the gene expression and signaling pathways in lacrimal gland. Differential gene expression analysis between lacrimal gland and other embryologically similar tissues may be helpful in furthering our understanding of lacrimal gland development...
2017: PloS One
https://www.readbyqxmd.com/read/28078171/could-revision-of-the-embryology-influence-our-cesarean-delivery-technique-towards-an-optimized-cesarean-delivery-for-universal-use
#4
Michael Stark, Ospan Mynbaev, Yuri Vassilevski, Patrick Rozenberg
Until today, there is no standardized Cesarean Section method and many variations exist. The main variations concern the type of abdominal incision, usage of abdominal packs, suturing the uterus in one or two layers, and suturing the peritoneal layers or leaving them open. One of the questions is the optimal location of opening the uterus. Recently, omission of the bladder flap was recommended. The anatomy and histology as results from the embryological knowledge might help to solve this question. The working thesis is that the higher the incision is done, the more damage to muscle tissue can take place contrary to incision in the lower segment, where fibrous tissue prevails...
July 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28061351/new-insights-into-early-human-development-lessons-for-stem-cell-derivation-and-differentiation
#5
REVIEW
Janet Rossant, Patrick P L Tam
Pathways underlying mouse embryonic development have always informed efforts to derive, maintain, and drive differentiation of human pluripotent stem cells. However, direct application of mouse embryology to the human system has not always been successful because of fundamental developmental differences between species. The naive pluripotent state of mouse embryonic stem cells (ESCs), in particular, has been difficult to capture in human ESCs, and appears to be transitory in the human embryo itself. Further studies of human and non-human primate embryo development are needed to untangle the complexities of pluripotency networks across mammalian species...
January 5, 2017: Cell Stem Cell
https://www.readbyqxmd.com/read/28059604/valentin-haecker-1864-1927-as-a-pioneer-of-phenogenetics-building-the-bridge-between-genotype-and-phenotype
#6
Uwe Hoßfeld, Elizabeth Watts, Georgy S Levit
Valentin Haecker is one of the forerunners of experimental biology, genetics, and developmental physiology. Haecker introduced the term Phänogenetik (phenogenetics) in 1918 in Entwicklungsgeschichtliche Eigenschaftsanalyse (Evolutionary Analysis of Characters), in which he described the earliest stages in the development of the phenotype. (1) His major objective in this publication was to integrate the two most important concepts of Mendelian genetics-phenotype and genotype-within a well-articulated theory...
January 6, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/28057875/perceived-challenges-of-working-in-a-fertility-clinic-a-qualitative-analysis-of-work-stressors-and-difficulties-working-with-patients
#7
Jacky Boivin, Laura Bunting, Emily Koert, Chin Ieng U, Christianne Verhaak
STUDY QUESTION: What are some of the challenges of working in a fertility clinic? SUMMARY ANSWER: The most frequently mentioned challenges were workload (e.g. high time pressure) and patient-related sources (e.g. unrealistic expectations). WHAT IS KNOWN ALREADY: One study showed a too high workload, worry about handling human material and low success rates were main stressors in fertility clinics. STUDY DESIGN, SIZE, DURATION: An online open-ended survey inviting participants to respond to seven questions was distributed to 5902 members of the European Society for Human Reproduction and Embryology (ESHRE, October 2010)...
January 5, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28057562/imaging-retina-to-study-dementia-and-stroke
#8
REVIEW
Carol Yim-Lui Cheung, M Kamran Ikram, Christopher Chen, Tien Yin Wong
With increase in life expectancy, the number of persons suffering from common age-related brain diseases, including neurodegenerative (e.g., dementia) and cerebrovascular (e.g., stroke) disease is expected to rise substantially. As current neuro-imaging modalities such as magnetic resonance imaging may not be able to detect subtle subclinical changes (resolution <100-500 μm) in dementia and stroke, there is an urgent need for other complementary techniques to probe the pathophysiology of these diseases...
January 2, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28050077/retrocaval-ureter-or-preureteral-vena-cava-lest-we-forget-this-rare-cause-of-hydronephrosis
#9
Saikat Bhattacharjee, Sunil Sanga, Pooja Gupta, R A George
Retrocaval ureter or circumcaval ureter is a rare congenital abnormality arising from dysgenesis of the inferior vena cava (IVC) that results in the right ureter coursing behind and medial to the IVC. The ideal nomenclature for the anomaly is preureteral vena cava, keeping in mind the aberrant embryology. It can result in hydronephrosis and is a rare cause of long-standing cyclical pain abdomen. Ultrasound, intravenous urography, nuclear scintigraphy, computed tomography urography (CTU) and magnetic resonance urography (MRU) have been used in the diagnosis of this abnormality but CTU, with its ability to depict the abnormality in three dimensions gives the most "wholesome" solution to its diagnosis...
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28050065/mapping-the-milestones-in-tooth-regeneration-current-trends-and-future-research
#10
REVIEW
Atanu Bhanja, D S J D'Souza
Research into finding the perfect replacement for lost dentition is an ever-evolving and rapidly advancing subject involving many scientific disciplines. The present consensus appears to be that regeneration of tooth in morphological and functional form is the ideal answer to lost tooth replacement. This article traces the milestones in this elusive search for the ultimate tooth replacement. The various research developments are highlighted that are aimed at the final goal of being able to "re-grow a natural tooth"...
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28049837/dinosaur-incubation-periods-directly-determined-from-growth-line-counts-in-embryonic-teeth-show-reptilian-grade-development
#11
Gregory M Erickson, Darla K Zelenitsky, David Ian Kay, Mark A Norell
Birds stand out from other egg-laying amniotes by producing relatively small numbers of large eggs with very short incubation periods (average 11-85 d). This aspect promotes high survivorship by limiting exposure to predation and environmental perturbation, allows for larger more fit young, and facilitates rapid attainment of adult size. Birds are living dinosaurs; their rapid development has been considered to reflect the primitive dinosaurian condition. Here, nonavian dinosaurian incubation periods in both small and large ornithischian taxa are empirically determined through growth-line counts in embryonic teeth...
January 3, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28049688/from-stem-cells-to-human-development-a-distinctly-human-perspective-on-early-embryology-cellular-differentiation-and-translational-research
#12
REVIEW
April M Craft, Matthew Johnson
Over 100 scientists with common interests in human development, disease and regeneration gathered in late September 2016 for The Company of Biologists' second 'From Stem Cells to Human Development' meeting held in historic Southbridge. In this Meeting Review, we highlight some of the exciting new findings that were presented, and discuss emerging themes and convergences in human development and disease that arose during these discussions.
January 1, 2017: Development
https://www.readbyqxmd.com/read/28031973/life-as-an-early-career-researcher-interview-with-heloisa-helena-milioli
#13
Heloisa Helena Milioli
Heloisa Helena Milioli speaks to Francesca Lake, Managing Editor: Heloisa received a BSc degree in Biological Sciences (2008) from the Universidade Federal de Santa Catarina (Brazil) and obtained a MSc degree in Genetics (2011) from Universidade Federal do Paraná (Brazil). In 2011 and 2012, she worked as a lecturer and tutor in the Department of Cell Biology, Embryology and Genetics (Universidade Federal de Santa Catarina). She moved to Australia in 2012 to obtain her PhD in Biological Sciences, with emphasis on Bioinformatics, from The University of Newcastle...
June 2016: Future Science OA
https://www.readbyqxmd.com/read/28031647/are-congenital-arteriovenous-malformations-of-proximal-upper-extremity-more-on-the-right-case-report-and-literature-review
#14
Satyen Parida, Sumanlata Gupta, B V Sai Chandran
This is a case of a 9-year-old boy with a congenital arteriovenous malformation (AVM) of the right upper extremity arising from the right subclavian artery. He underwent open surgical excision of the vascular tumor. Upon reviewing the literature, a high incidence of right-sided congenital AVM of the proximal upper extremity was identified. It has been suggested that this high incidence may be related to the complexity of the embryologic development of the right subclavian artery.
December 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28031323/inter-observer-and-intra-observer-agreement-between-embryologists-during-selection-of-a-single-day-5-embryo-for-transfer-a-multicenter-study
#15
Ashleigh Storr, Christos A Venetis, Simon Cooke, Suha Kilani, William Ledger
STUDY QUESTION: What is the inter-observer and intra-observer agreement between embryologists when selecting a single Day 5 embryo for transfer? SUMMARY ANSWER: The inter-observer and intra-observer agreement between embryologists when selecting a single Day 5 embryo for transfer was generally good, although not optimal, even among experienced embryologists. WHAT IS KNOWN ALREADY: Previous research on the morphological assessment of early stage (two pronuclei to Day 3) embryos has shown varying levels of inter-observer and intra-observer agreement...
December 28, 2016: Human Reproduction
https://www.readbyqxmd.com/read/28027612/nonobliteration-of-the-processus-vaginalis-sonography-of-related-abnormalities-in-children
#16
Vasileios Rafailidis, Sotirios Varelas, Foteini Apostolopoulou, Dimitrios Rafailidis
The objective of this pictorial essay is to systematically classify processus vaginalis-related disorders in the light of embryology and present illustrative sonograms with corresponding diagrams. Failure of the processus vaginalis to obliterate during gestation results in a wide spectrum of anomalies, including communicating and noncommunicating hydroceles and inguinal and inguinoscrotal hernias, along with other related disorders of the genital system. There are varying classifications in the literature regarding the aforementioned entities...
April 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28024878/congenital-anomalies-of-the-pulmonary-arteries-spectrum-of-findings-on-computed-tomography
#17
J Bueno, L Flors, M Mejía
OBJECTIVE: Congenital anomalies of the pulmonary arteries are uncommon. They can occur in isolation or in association with congenital heart defects. Isolated congenital anomalies remain undiscovered until they are reported as incidental findings on imaging tests, usually not until adolescence. We review the embryological development and normal anatomy of the pulmonary arteries as well as the spectrum of computed tomography findings for various congenital anomalies: unilateral interruption of the pulmonary artery, anomalous origin of the left pulmonary artery (pulmonary artery sling), idiopathic aneurysm of the pulmonary artery, and other anomalies associated with congenital heart defects...
December 23, 2016: Radiología
https://www.readbyqxmd.com/read/28012595/orbital-autoimmune-inflammatory-disorders-protein-regional-variability-might-explain-specific-lesion-location
#18
Margo S Clarke, Alexandre Plouznikoff, Jean Deschenes
In ophthalmology, inflammatory diseases target different highly specific regions within the small confine of the orbit. Some entities even prefer a particular location or depth within the same tissue (ex. anterior, intermediate or posterior uveitides, chorioretinitides with unique topographic presentations). Though the location of a lesion strongly influences and helps us in our differential diagnosis, we still don't understand why specific anatomic sites are susceptible to a disease while other areas are spared...
January 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28010951/utility-of-ward-based-retinal-photography-in-stroke-patients
#19
Shaun Frost, Michael Brown, Verity Stirling, Janardhan Vignarajan, David Prentice, Yogesan Kanagasingam
BACKGROUND: Improvements in acute care of stroke patients have decreased mortality, but survivors are still at increased risk of future vascular events and mitigation of this risk requires thorough assessment of the underlying factors leading to the stroke. The brain and eye share a common embryological origin and numerous similarities exist between the small vessels of the retina and brain. Recent population-based studies have demonstrated a close link between retinal vascular changes and stroke, suggesting that retinal photography could have utility in assessing underlying stroke risk factors and prognosis after stroke...
December 20, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28009801/classification-of-cruciate-ligament-dysplasia-and-the-severity-of-congenital-fibular-deficiency
#20
Janet L Walker, Todd A Milbrandt, Henry J Iwinski, Vishwas R Talwalkar
BACKGROUND: Dysplasia of the cruciate ligaments has been found in many patients with congenital fibular deficiency. A recent classification system has shown that radiographic tibial spine changes can predict the hypoplasia and aplasia of the cruciate ligaments. We used this radiographic classification to determine the frequency of these abnormalities and how they correlate with the severity of fibular deficiency and lateral femoral condylar hypoplasia. METHODS: Using a hospital database search for fibular deficiency, 99 patients ≥6 years with unilateral fibular deficiency were identified...
December 22, 2016: Journal of Pediatric Orthopedics
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