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https://www.readbyqxmd.com/read/28346134/five-key-recommendations-for-the-implementation-of-hospital-electronic-prescribing-and-medicines-administration-systems-in-scotland
#1
Kathrin Cresswell, Ann Slee, Aziz Sheikh
NHS Scotland is about to embark on the implementation of Hospital Electronic Prescribing and Medicines Administration (HEPMA) systems. There are a number of risks associated with such ventures, thus drawing on existing experiences from other settings is crucial in informing deployment.Drawing on our previous and ongoing work in English settings as well as the international literature, we reflect on key lessons that NHS Scotland may wish to consider in going forward. These deliberations include recommendations surrounding key aspects of deployment strategy surrounding: 1) the way central coordination should be conceptualised, 2) how flexibility in can be ensured, 3) paying attention to optimising systems from the outset, 4) how expertise should be developed and centrally shared, and 5) ways in which learning from experience can be maximised...
January 24, 2017: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28345872/intrinsically-stretchable-and-conductive-textile-by-a-scalable-process-for-elastic-wearable-electronics
#2
Chunya Wang, Mingchao Zhang, Kailun Xia, Xueqin Gong, Huimin Wang, Zhe Yin, Baolu Guan, Yingying Zhang
The prosperous development of stretchable electronics poses great demand in stretchable conductive materials which could maintain their electrical conductivity under tensile strain. Previously reported strategies to obtain stretchable conductors usually involve complex structure-fabricating processes or utilization of high-cost nanomaterials. It remains a great challenge to produce stretchable and conductive materials via a scalable and cost-effective process. A large-scalable pyrolysis strategy is developed for the fabrication of intrinsically stretchable and conductive textile utilizing low-cost and mass-produced weft-knitted textiles as raw materials...
March 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28345584/terahertz-and-mid-infrared-plasmons-in-three-dimensional-nanoporous-graphene
#3
Fausto D'Apuzzo, Alba R Piacenti, Flavio Giorgianni, Marta Autore, Mariangela Cestelli Guidi, Augusto Marcelli, Ulrich Schade, Yoshikazu Ito, Mingwei Chen, Stefano Lupi
Two-dimensional (2D) graphene emerged as an outstanding material for plasmonic and photonic applications due to its charge-density tunability, high electron mobility, optical transparency and mechanical flexibility. Recently, novel fabrication processes have realised a three-dimensional (3D) nanoporous configuration of high-quality monolayer graphene which provides a third dimension to this material. In this work, we investigate the optical behaviour of nanoporous graphene by means of terahertz and infrared spectroscopy...
March 27, 2017: Nature Communications
https://www.readbyqxmd.com/read/28345340/excluded-volume-approach-for-ultrathin-carbon-nanotube-network-stabilization-a-mesoscopic-distinct-element-method-study
#4
Yuezhou Wang, Grigorii Drozdov, Erik K Hobbie, Traian Dumitrica
Ultrathin carbon nanotube films have gathered attention for flexible electronics applications. Unfortunately, their network structure changes significantly even under small applied strains. We perform mesoscopic distinct element method simulations and develop an atomic scale picture of the network stress relaxation. On this basis, we put forward the concept of mesoscale design by the addition of excluded-volume interactions. We integrate silicon nanoparticles into our model and show that the nanoparticle-filled networks present superior stability and mechanical response relative to pure films...
March 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28345045/bend-stretch-and-touch-locating-a-finger-on-an-actively-deformed-transparent-sensor-array
#5
Mirza Saquib Sarwar, Yuta Dobashi, Claire Preston, Justin K M Wyss, Shahriar Mirabbasi, John David Wyndham Madden
The development of bendable, stretchable, and transparent touch sensors is an emerging technological goal in a variety of fields, including electronic skin, wearables, and flexible handheld devices. Although transparent tactile sensors based on metal mesh, carbon nanotubes, and silver nanowires demonstrate operation in bent configurations, we present a technology that extends the operation modes to the sensing of finger proximity including light touch during active bending and even stretching. This is accomplished using stretchable and ionically conductive hydrogel electrodes, which project electric field above the sensor to couple with and sense a finger...
March 2017: Science Advances
https://www.readbyqxmd.com/read/28343389/mechanical-properties-of-organic-semiconductors-for-stretchable-highly-flexible-and-mechanically-robust-electronics
#6
Samuel E Root, Suchol Savagatrup, Adam D Printz, Daniel Rodriquez, Darren J Lipomi
Mechanical deformability underpins many of the advantages of organic semiconductors. The mechanical properties of these materials are, however, diverse, and the molecular characteristics that permit charge transport can render the materials stiff and brittle. This review is a comprehensive description of the molecular and morphological parameters that govern the mechanical properties of organic semiconductors. Particular attention is paid to ways in which mechanical deformability and electronic performance can coexist...
March 25, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28342396/high-resolution-cryo-em-the-nuts-and-bolts
#7
REVIEW
Dominika Elmlund, Sarah N Le, Hans Elmlund
Cryogenic electron microscopy (cryo-EM) and single-particle analysis now enables the determination of high-resolution structures of macromolecular assemblies that have resisted X-ray crystallography and other approaches. Successful high-resolution structure determination by cryo-EM always depends on the quality of the protein sample. While structural heterogeneity remains a key challenge for cryo-EM, it also represents a rare opportunity to study the intrinsic conformational flexibility of macromolecular assemblies...
March 22, 2017: Current Opinion in Structural Biology
https://www.readbyqxmd.com/read/28340521/stable-and-controllable-synthesis-of-silver-nanowires-for-transparent-conducting-film
#8
Bitao Liu, Hengqing Yan, Shanyong Chen, Youwei Guan, Guoguo Wu, Rong Jin, Lu Li
Silver nanowires without particles are synthesized by a solvothermal method at temperature 150 °C. Silver nanowires are prepared via a reducing agent of glycerol and a capping agent of polyvinylpyrrolidone (M w  ≈ 1,300,000). Both of them can improve the purity of the as-prepared silver nanowires. With controllable shapes and sizes, silver nanowires are grown continuously up to 10-20 μm in length with 40-50 nm in diameter. To improve the yield of silver nanowires, the different concentrations of AgNO3 synthesis silver nanowires are discussed...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28340512/activation-mechanisms-of-%C3%AE-v%C3%AE-3-integrin-by-binding-to-fibronectin-a-computational-study
#9
Lingyun Wang, Di Pan, Qi Yan, Yuhua Song
Integrin αVβ3 plays an important role in regulating cellular activities and in human diseases. Although the structure of αVβ3 has been studied by crystallography and electron microscopy, the detailed activation mechanism of integrin αVβ3 induced by fibronectin (Fn) remains unclear. In this study, we investigated the conformational and dynamical motion changes of Mn(2+) -bound integrin αVβ3 by binding to Fn with molecular dynamics simulations. Results showed that Fn binding to integrin αVβ3 caused the changes of the conformational flexibility of αVβ3 domains, the essential mode of motion for the domains of αV subunit and β3 subunit and the degrees of correlated motion of residues between the domains of αV subunit and β3 subunit of integrin αVβ3...
March 24, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28340241/pragmatic-trial-informatics-a-perspective-from-the-nih-health-care-systems-research-collaboratory
#10
Rachel L Richesson, Beverly B Green, Reesa Laws, Jon Puro, Michael G Kahn, Alan Bauck, Michelle Smerek, Erik G Van Eaton, Meredith Zozus, W Ed Hammond, Kari A Stephens, Greg E Simon
Pragmatic clinical trials (PCTs) are research investigations embedded in health care settings designed to increase the efficiency of research and its relevance to clinical practice. The Health Care Systems Research Collaboratory, initiated by the National Institutes of Health Common Fund in 2010, is a pioneering cooperative aimed at identifying and overcoming operational challenges to pragmatic research. Drawing from our experience, we present 4 broad categories of informatics-related challenges: (1) using clinical data for research, (2) integrating data from heterogeneous systems, (3) using electronic health records to support intervention delivery or health system change, and (4) assessing and improving data capture to define study populations and outcomes...
March 14, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28338607/how-to-make-reliable-washable-and-wearable-textronic-devices
#11
Xuyuan Tao, Vladan Koncar, Tzu-Hao Huang, Chien-Lung Shen, Ya-Chi Ko, Gwo-Tsuen Jou
In this paper, the washability of wearable textronic (textile-electronic) devices has been studied. Two different approaches aiming at designing, producing, and testing robust washable and reliable smart textile systems are presented. The common point of the two approaches is the use of flexible conductive PCB in order to interface the miniaturized rigid (traditional) electronic devices to conductive threads and tracks within the textile flexible fabric and to connect them to antenna, textile electrodes, sensors, actuators, etc...
March 24, 2017: Sensors
https://www.readbyqxmd.com/read/28338429/study-on-the-release-of-carbon-nanoparticles-of-different-size-and-shape-from-nanocomposite-poly-lactic-acid-film-into-food-simulants
#12
Hristiana Velichkova, Stanislav Kotsilkov, Evgeni Ivanov, Rumiana Kotsilkova, Stanislav Gyoshev, Nikolay Stoimenov, Nikolay K Vitanov
Poly(lactic) acid (PLA) film with 2 wt % mixed carbon nanofillers of graphene nanoplates (GNPs) and multiwall carbon nanotubes (MWCNTs) in weight ratio 1:1 with impurities of fullerene and carbon black (CB) was produced by layer to layer deposition and hot pressing. The release of carbon nanoparticles from the film was studied at varying time-temperature conditions and simulants. Migrants in simulant solvents were examined with laser diffraction analysis and transmission electron microscopy. The film integrity and the presence of migrants on the film surfaces were visualized by scanning electron microscopy...
March 24, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28338313/ultimate-control-of-rate-dependent-adhesion-for-reversible-transfer-process-via-thin-elastomeric-layer
#13
Chan Kim, Min-Ah Yoon, Bongkyun Jang, Jae-Hyun Kim, Hak-Joo Lee, Kwang-Seop Kim
Adhesion between a stamp with an elastomeric layer and various devices or substrates is crucial to successfully fabricate flexible electronics using a transfer process. Although various transfer processes using stamps with different adhesion strengths have been suggested, the controllable range of adhesion is still limited to a narrow range. To precisely transfer devices onto selected substrates, however, the difference in adhesion between the picking and placing processes should be large enough to achieve a high yield...
March 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28337979/monolayer-optical-memory-cells-based-on-artificial-trap-mediated-charge-storage-and-release
#14
Juwon Lee, Sangyeon Pak, Young-Woo Lee, Yuljae Cho, John Hong, Paul Giraud, Hyeon Suk Shin, Stephen M Morris, Jung Inn Sohn, SeungNam Cha, Jong Min Kim
Monolayer transition metal dichalcogenides are considered to be promising candidates for flexible and transparent optoelectronics applications due to their direct bandgap and strong light-matter interactions. Although several monolayer-based photodetectors have been demonstrated, single-layered optical memory devices suitable for high-quality image sensing have received little attention. Here we report a concept for monolayer MoS2 optoelectronic memory devices using artificially-structured charge trap layers through the functionalization of the monolayer/dielectric interfaces, leading to localized electronic states that serve as a basis for electrically-induced charge trapping and optically-mediated charge release...
March 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28336911/2d-hybrid-analysis-approach-for-building-three-dimensional-atomic-model-by-electron-microscopy-image-matching
#15
Atsushi Matsumoto, Naoyuki Miyazaki, Junichi Takagi, Kenji Iwasaki
In this study, we develop an approach termed "2D hybrid analysis" for building atomic models by image matching from electron microscopy (EM) images of biological molecules. The key advantage is that it is applicable to flexible molecules, which are difficult to analyze by 3DEM approach. In the proposed approach, first, a lot of atomic models with different conformations are built by computer simulation. Then, simulated EM images are built from each atomic model. Finally, they are compared with the experimental EM image...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28336065/folding-and-dynamics-based-electrochemical-dna-sensors
#16
Rebecca Y Lai
A number of electrochemical DNA sensors based on the target-induced change in the conformation and/or flexibility of surface-bound oligonucleotides have been developed in recent years. These sensors, which are often termed E-DNA sensors, are comprised of an oligonucleotide probe modified with a redox label (e.g., methylene blue) at one terminus and attached to a gold electrode via a thiol-gold bond at the other. Binding of the target to the DNA probe changes its structure and dynamics, which, in turn, influences the efficiency of electron transfer to the interrogating electrode...
2017: Methods in Enzymology
https://www.readbyqxmd.com/read/28335282/inverter-circuits-using-zno-nanoparticle-based-thin-film-transistors-for-flexible-electronic-applications
#17
Fábio F Vidor, Thorsten Meyers, Ulrich Hilleringmann
Innovative systems exploring the flexibility and the transparency of modern semiconducting materials are being widely researched by the scientific community and by several companies. For a low-cost production and large surface area applications, thin-film transistors (TFTs) are the key elements driving the system currents. In order to maintain a cost efficient integration process, solution based materials are used as they show an outstanding tradeoff between cost and system complexity. In this paper, we discuss the integration process of ZnO nanoparticle TFTs using a high-k resin as gate dielectric...
August 23, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335276/flexible-textile-based-organic-transistors-using-graphene-ag-nanoparticle-electrode
#18
Youn Kim, Yeon Ju Kwon, Kang Eun Lee, Youngseok Oh, Moon-Kwang Um, Dong Gi Seong, Jea Uk Lee
Highly flexible and electrically-conductive multifunctional textiles are desirable for use in wearable electronic applications. In this study, we fabricated multifunctional textile composites by vacuum filtration and wet-transfer of graphene oxide films on a flexible polyethylene terephthalate (PET) textile in association with embedding Ag nanoparticles (AgNPs) to improve the electrical conductivity. A flexible organic transistor can be developed by direct transfer of a dielectric/semiconducting double layer on the graphene/AgNP textile composite, where the textile composite was used as both flexible substrate and conductive gate electrode...
August 16, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335239/a-flexible-360-degree-thermal-sound-source-based-on-laser-induced-graphene
#19
Lu-Qi Tao, Ying Liu, Zhen-Yi Ju, He Tian, Qian-Yi Xie, Yi Yang, Tian-Ling Ren
A flexible sound source is essential in a whole flexible system. It's hard to integrate a conventional sound source based on a piezoelectric part into a whole flexible system. Moreover, the sound pressure from the back side of a sound source is usually weaker than that from the front side. With the help of direct laser writing (DLW) technology, the fabrication of a flexible 360-degree thermal sound source becomes possible. A 650-nm low-power laser was used to reduce the graphene oxide (GO). The stripped laser induced graphene thermal sound source was then attached to the surface of a cylindrical bottle so that it could emit sound in a 360-degree direction...
June 7, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335216/investigation-of-the-structural-electrical-and-optical-properties-of-the-nano-scale-gzo-thin-films-on-glass-and-flexible-polyimide-substrates
#20
Fang-Hsing Wang, Kun-Neng Chen, Chao-Ming Hsu, Min-Chu Liu, Cheng-Fu Yang
In this study, Ga₂O₃-doped ZnO (GZO) thin films were deposited on glass and flexible polyimide (PI) substrates at room temperature (300 K), 373 K, and 473 K by the radio frequency (RF) magnetron sputtering method. After finding the deposition rate, all the GZO thin films with a nano-scale thickness of about 150 ± 10 nm were controlled by the deposition time. X-ray diffraction patterns indicated that the GZO thin films were not amorphous and all exhibited the (002) peak, and field emission scanning electron microscopy showed that only nano-scale particles were observed...
May 10, 2016: Nanomaterials
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