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https://www.readbyqxmd.com/read/28723767/return-of-the-cadaver-key-role-of-anatomic-dissection-for-plastic-surgery-resident-training
#1
Swenn Maxence Krähenbühl, Paul Čvančara, Thomas Stieglitz, Raphaël Bonvin, Murielle Michetti, Marjorie Flahaut, Sébastien Durand, Lina Deghayli, Lee Ann Applegate, Wassim Raffoul
Successful Plastic Surgery Residency training is subjected to evolving society pressure of lower hourly work weeks imposed by external committees, labor laws, and increased public awareness of patient care quality. Although innovative measures for simulation training of surgery are appearing, there is also the realization that basic anatomy training should be re-enforced and cadaver dissection is of utmost importance for surgical techniques.In the development of new technology for implantable neurostimulatory electrodes for the management of phantom limb pain in amputee patients, a design of a cadaveric model has been developed with detailed steps for innovative transfascicular insertion of electrodes...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28719718/cochlear-implant-electrode-array-exposure-a-delayed-complication
#2
Christina Mishu, David A Klodd, Miriam Redleaf
Exposure of the cochlear implant electrode array as a late complication has been reported rarely in the literature. A retrospective analysis revealed 4 patients presenting with exposure of their cochlear implant electrode arrays from 2 to 17 years after implantation. Data collected from these 4 patients were surgical implantation approach, type of implant, age at implant, interval between implant and complication, surgical correction of the problem, pathology at the time of correction, and length of follow-up after intervention...
July 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28718878/deep-brain-and-cortical-stimulation-for-epilepsy
#3
REVIEW
Mathieu Sprengers, Kristl Vonck, Evelien Carrette, Anthony G Marson, Paul Boon
BACKGROUND: Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. Since the 1970s interest has grown in invasive intracranial neurostimulation as a treatment for these patients. Intracranial stimulation includes both deep brain stimulation (DBS) (stimulation through depth electrodes) and cortical stimulation (subdural electrodes). This is an updated version of a previous Cochrane review published in 2014. OBJECTIVES: To assess the efficacy, safety and tolerability of DBS and cortical stimulation for refractory epilepsy based on randomized controlled trials (RCTs)...
July 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28715337/compact-energy-efficient-high-frequency-switched-capacitor-neural-stimulator-with-active-charge-balancing
#4
Wen-Yang Hsu, Alexandre Schmid
Safety and energy efficiency are two major concerns for implantable neural stimulators. This paper presents a novel high-frequency, switched capacitor (HFSC) stimulation and active charge balancing scheme, which achieves high energy efficiency and well-controlled stimulation charge in the presence of large electrode impedance variations. Furthermore, the HFSC can be implemented in a compact size without any external component to simultaneously enable multichannel stimulation by deploying multiple stimulators...
July 17, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28712991/low-beta-cortico-pallidal-coherence-decreases-during-movement-and-correlates-with-overall-reaction-time
#5
Bernadette C M van Wijk, Wolf-Julian Neumann, Gerd-Helge Schneider, Tilmann H Sander, Vladimir Litvak, Andrea A Kühn
Beta band oscillations (13-30 Hz) are a hallmark of cortical and subcortical structures that are part of the motor system. In addition to local population activity, oscillations also provide a means for synchronization of activity between regions. Here we examined the role of beta band coherence between the internal globus pallidus (GPi) and (motor) cortex during a simple reaction time task performed by nine patients with idiopathic dystonia. We recorded local field potentials from deep brain stimulation (DBS) electrodes implanted in bilateral GPi in combination with simultaneous whole-head magneto-encephalography (MEG)...
July 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28712018/laparoscopic-implantation-of-electrodes-for-bilateral-neuromodulation-of-the-pudendal-nerves-and-s3-nerve-roots-for-treating-pelvic-pain-and-voiding-dysfunction
#6
Adrienne L K Li, Renato Marques, Acary Oliveira, Laise Veloso, Manoel J B C Girão, Nucelio Lemos
INTRODUCTION AND HYPOTHESIS: The objective of this video is to describe the technique for laparoscopic implantation of electrodes for bilateral neuromodulation of S3 and pudendal nerves. We report a successful case of a 48-year-old woman with spina bifida occulta referred with a 14-year history of intense acyclic pelvic pain, urinary hesitancy, and intermittent flow refractory to various conservative measures. METHODS: The procedure began with the removal of two previously placed InterStims...
July 15, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28707160/systems-for-deep-brain-stimulation-review-of-technical-features
#7
REVIEW
A Amon, F Alesch
The use of deep brain stimulation (DBS) is an important treatment option for movement disorders and other medical conditions. Today, three major manufacturers provide implantable systems for DBS. Although the underlying principle is basically the same for all available systems, the differences in the technical features vary considerably. This article outlines aspects regarding the technical features of DBS systems. The differences between voltage and current sources are addressed and their effect on stimulation is shown...
July 13, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28706596/percutaneous-retrieval-of-a-knotted-provisional-pacemaker-using-proximal-electrode-cut-off-and-distal-end-snaring
#8
Mohsen Mohandes, Natalia Rodríguez, Francisco Fernández, Cristina Moreno, Oscar Palazón, Alfredo Bardají
Although provisional pacemaker implantation can safely be done in many cases, a rare complication such as knotted electrode has been described, especially when the procedure is performed without fluoroscopy guidance. We describe a case of knot creation in a provisional pacemaker which was successfully retrieved using a snare after cutting the electrode proximally.
April 2017: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/28705474/rf-ablation-in-periventricular-heterotopia-related-epilepsy
#9
Massimo Cossu, Laura Mirandola, Laura Tassi
Drug-resistant focal epilepsy is a common occurrence in patients with gray matter nodular heterotopia (NH), and surgical treatment is often considered in these cases. NH-related epileptogenicity is sustained by complex networks, which may involve the nodules and extralesional cortex in various combinations. Therefore, invasive EEG is usually required to identify the structures involved in seizure generation. It has been reported that surgery may be effective in cases with unilateral lesions, whereas bilateral cases are not optimal candidates for surgical success...
July 3, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28700894/preparation-of-an-au-pt-alloy-free-from-artifacts-in-magnetic-resonance-imaging
#10
Tomonobu Kodama, Ryusuke Nakai, Kenji Goto, Kunihiro Shima, Hiroo Iwata
PURPOSE: When magnetic resonance imaging (MRI) is performed on patients carrying metallic implants, artifacts can disturb the images around the implants, often making it difficult to interpret them appropriately. However, metallic materials are and will be indispensable as raw materials for medical devices because of their electric conductivity, visibility under X-ray fluoroscopy, and other favorable features. What is now desired is to develop a metallic material which causes no artifacts during MRI...
July 9, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28700446/pure-tone-masking-patterns-for-monopolar-and-phantom-electrical-stimulation-in-cochlear-implants
#11
Aniket A Saoji, Kanthaiah Koka, Leonid M Litvak, Charles C Finley
OBJECTIVES: Monopolar stimulation of the most apical electrode produces the lowest pitch sensation in cochlear implants clinically. A phantom electrode that uses out-of-phase electrical stimulation between the most apical and the neighboring basal electrode can produce a lower pitch sensation than that associated with the most apical electrode. However, because of the absence of contacts beyond the apical tip of the array, the ability to assess the spread of electrical excitation associated with phantom stimulation is limited in the typical cochlear implant subject with no residual hearing...
July 11, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28700445/auditory-brainstem-implant-array-position-varies-widely-among-adult-and-pediatric-patients-and-is-associated-with-perception
#12
Samuel R Barber, Elliott D Kozin, Aaron K Remenschneider, Sidharth V Puram, Max Smith, Barbara S Herrmann, Mary E Cunnane, M Christian Brown, Daniel J Lee
OBJECTIVES: The auditory brainstem implant (ABI) provides sound awareness to patients who are ineligible for cochlear implantation. Auditory performance varies widely among similar ABI cohorts. We hypothesize that differences in electrode array position contribute to this variance. Herein, we classify ABI array position based on postoperative imaging and investigate the relationship between position and perception. DESIGN: Retrospective review of pediatric and adult ABI users with postoperative computed tomography...
July 11, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28700398/the-role-of-preoperative-steroids-in-atraumatic-cochlear-implantation-surgery
#13
Jonathon Lo, Luke Campbell, Phillip Sale, Scott Chambers, Amy Hampson, Hayden Eastwood, Stephen O'Leary
HYPOTHESIS: Depth of insertion is related to the extent of tissue response and low frequency hearing loss. Intravenous steroids have greatest effect in reducing postimplantation fibrosis and hearing loss in the presence of significant electrode insertion trauma, when compared with saline treatment. BACKGROUND: Experiments exploring the enhancement of cochlear implantation (CI) outcomes with glucocorticosteroids have produced mixed results, possibly due to lack of standardization of the CI model...
July 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28699322/a-respiratory-marker-derived-from-left-vagus-nerve-signals-recorded-with-implantable-cuff-electrodes
#14
Cristian Sevcencu, Thomas N Nielsen, Benedict Kjaergaard, Johannes J Struijk
OBJECTIVE: Left vagus nerve (LVN) stimulation (LVNS) has been tested for lowering the blood pressure (BP) in patients with resistant hypertension (RH). Whereas, closed-loop LVNS (CL-LVNS) driven by a BP marker may be superior to open-loop LVNS, there are situations (e.g., exercising) when hypertension is normal. Therefore, an ideal anti-RH CL-LVNS system requires a variable to avoid stimulation in such conditions, for example, a respiratory marker ideally extracted from the LVN. As the LVN conducts respiratory signals, this study aimed to investigate if such signals can be recorded using implantable means and if a marker to monitor respiration could be derived from such recordings...
July 11, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28698470/real-time-amperometric-recording-of-extracellular-h%C3%A2-o%C3%A2-in-the-brain-of-immunocompromised-mice-an-in-vitro-ex-vivo-and-in-vivo-characterisation-study
#15
Caroline H Reid, Niall J Finnerty
We detail an extensive characterisation study on a previously described dual amperometric H₂O₂ biosensor consisting of H₂O₂ detection (blank) and degradation (catalase) electrodes. In vitro investigations demonstrated excellent H₂O₂ sensitivity and selectivity against the interferent, ascorbic acid. Ex vivo studies were performed to mimic physiological conditions prior to in vivo deployment. Exposure to brain tissue homogenate identified reliable sensitivity and selectivity recordings up to seven days for both blank and catalase electrodes...
July 8, 2017: Sensors
https://www.readbyqxmd.com/read/28697658/determining-the-minimum-number-of-electrodes-that-need-to-be-pitch-matched-to-accurately-estimate-pitch-matches-across-the-array
#16
Julia Stelmach, David M Landsberger, Monica Padilla, Justin M Aronoff
OBJECTIVE: With bilateral cochlear implant (CI) users there is typically a place mismatch between the locations stimulated by the left and right electrode arrays. This mismatch can affect performance, potentially limiting binaural benefits. One way to address this is by perceptually realigning the arrays such that a given frequency in the input stimulates perceptually matched locations in the two ears. A clinically feasible technique is needed that can determine the appropriate perceptual alignment...
July 12, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28695839/rapid-prototyping-of-flexible-intrafascicular-electrode-arrays-by-picosecond-laser-structuring
#17
Matthias Mueller, Natalia de la Oliva, Jaume Del Valle, Ignacio Delgado Martinez, Xavier Navarro, Thomas Stieglitz
Interfacing the peripheral nervous system can be performed with a large variety of electrode arrays. However, stimulating and recording a nerve while having a reasonable amount of channels limits the number of available systems. Translational research towards human clinical trial requires device safety and biocompatibility but would benefit from design flexibility in the development process to individualize probes. Approach. We selected established medical grade implant materials like precious metals and parylene C to develop a rapid prototyping process for novel intrafascicular electrode arrays using a picosecond laser structuring...
July 11, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28693584/-long-term-stability-of-stimulating-spiral-nerve-cuff-electrodes-on-human-peripheral-nerves
#18
Breanne P Christie, Max Freeberg, William D Memberg, Gilles J C Pinault, Harry A Hoyen, Dustin J Tyler, Ronald J Triolo
BACKGROUND: Electrical stimulation of the peripheral nerves has been shown to be effective in restoring sensory and motor functions in the lower and upper extremities. This neural stimulation can be applied via non-penetrating spiral nerve cuff electrodes, though minimal information has been published regarding their long-term performance for multiple years after implantation. METHODS: Since 2005, 14 human volunteers with cervical or thoracic spinal cord injuries, or upper limb amputation, were chronically implanted with a total of 50 spiral nerve cuff electrodes on 10 different nerves (mean time post-implant 6...
July 11, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28691204/mortality-with-brainstem-seizures-from-focal-4-aminopyridine-induced-recurrent-hippocampal-seizures
#19
Muhammad Tariqus Salam, Gaspard Montandon, Roman Genov, Orrin Devinsky, Martin Del Campo, Peter L Carlen
OBJECTIVE: Sudden unexplained death in epilepsy is the leading cause of death in young adult epilepsy patients, typically occurring during the early postictal period, presumably resulting from brainstem and cardiorespiratory dysfunction. We hypothesized that ictal discharges in the brainstem disrupt the cardiorespiratory network, causing mortality. To study this hypothesis, we chose an animal model comprising focal unilateral hippocampal injection of 4-aminopyridine (4-AP), which produced focal recurrent hippocampal seizures with secondary generalization in awake, behaving rats...
July 10, 2017: Epilepsia
https://www.readbyqxmd.com/read/28690494/the-electrically-evoked-compound-action-potential-from-laboratory-to-clinic
#20
REVIEW
Shuman He, Holly F B Teagle, Craig A Buchman
The electrically evoked compound action potential (eCAP) represents the synchronous firing of a population of electrically stimulated auditory nerve fibers. It can be directly recorded on a surgically exposed nerve trunk in animals or from an intra-cochlear electrode of a cochlear implant. In the past two decades, the eCAP has been widely recorded in both animals and clinical patient populations using different testing paradigms. This paper provides an overview of recording methodologies and response characteristics of the eCAP, as well as its potential applications in research and clinical situations...
2017: Frontiers in Neuroscience
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