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marriage therapy

Matthew L Paff, Scott L Nuismer, Andrew D Ellington, Ian J Molineux, Ryan H May, James J Bull
BACKGROUND: We propose, model, and implement a novel system of population-level intervention against a virus. One context is a treatment against a chronic infection such as HIV. The underlying principle is a form of virus 'wars' in which a benign, transmissible agent is engineered to protect against infection by and spread of a lethal virus. In our specific case, the protective agent consists of two entities, a benign virus and a gene therapy vector mobilized by the benign virus. RESULTS: Numerical analysis of a mathematical model identified parameter ranges in which adequate, population-wide protection is achieved...
2016: Journal of Biological Engineering
Assi Dahan, Lior Noy, Yuval Hart, Avi Mayo, Uri Alon
Motion synchrony correlates with effective and well-rated human interaction. However, people do not remain locked in synchrony; Instead, they repeatedly enter and exit synchrony. In many important interactions, such as therapy, marriage and parent-infant communication, it is the ability to exit and then re-enter synchrony that is thought to build strong relationship. The phenomenon of entry into zero-phase synchrony is well-studied experimentally and in terms of mathematical modeling. In contrast, exit-from-synchrony is under-studied...
2016: PloS One
Mathew C Withers, Jamila E Reynolds, Kayla Reed, Kendal Holtrop
Despite the considerable resources allocated to research to promote public health, interventions capable of benefiting individuals and families are not finding their way into regular practice. An important avenue for addressing this problem is through dissemination and implementation (D&I) science, a burgeoning research area focusing on translating empirical knowledge into everyday practice. This article begins by suggesting ways in which MFTs are uniquely equipped to contribute to and benefit from D&I research...
October 4, 2016: Journal of Marital and Family Therapy
Adrian J Blow, Eli A Karam
In this paper we argue that the therapist is a crucial change variable in psychotherapy as a whole and in couple, marital, and family therapy specifically. Therapists who work with complex systems require more skills to negotiate demanding therapy contexts. Yet, little is known about what differentiates effective couple, marital, and family therapists from those who are less effective, what innate therapy skills they possess, how they learn, and how they operationalize their knowledge in the therapy room. We discuss the need to emphasize evidence based therapists (as opposed to therapies), and implications of the importance of the role therapists for training, practice, research priorities, and policy...
September 30, 2016: Administration and Policy in Mental Health
E Bukhari, F Alaklobi, H Bakheet, A Alrabiaah, F Alotibi, F Aljobair, M Alshamrani, E Alaki, F Alnahdi, A Alodyani, F Alzamil
OBJECTIVE: The bacille Calmette Guérin (BCG) vaccine is administered worldwide to prevent tuberculosis. Although, Post BCG vaccination complications like disseminated BCG infections are rare and immunocompromised children are at high risk of developing BCG-related complications including BCG-lymphadenitis and other disseminated diseases. PATIENTS AND METHODS: This was a prospective study of children who developed disseminated BCG after vaccination who were admitted in three tertiary care hospital in Riyadh, Saudi Arabia, in the year 2015...
September 2016: European Review for Medical and Pharmacological Sciences
Reem Waziry, Jason Grebely, Janaki Amin, Maryam Alavi, Behzad Hajarizadeh, Jacob George, Gail V Matthews, Matthew Law, Gregory J Dore
BACKGROUND & AIMS: This study evaluates trends in hepatocellular carcinoma (HCC) among people with hepatitis B virus (HBV) or hepatitis C virus (HCV) infection in New South Wales (NSW), Australia between 2000 and 2014. METHODS: Data on HBV and HCV notifications between January 1993 and December 2012 were linked to the NSW Admitted Patients Data Collection database between July 2000 and June 2014 and NSW Registry of Births Deaths and Marriages. The burden, crude and age-standardised incidence of HCC based on first hospitalization were calculated...
August 26, 2016: Journal of Hepatology
Yiping Chen, Caihua Wang, Jinyu Wang, Leilei Zheng, Weibo Liu, Huichun Li, Shaohua Yu, Bin Pan, Hualiang Yu, Risheng Yu
This study was to investigate the association of psychological characteristics and functional dyspepsia treatment outcome. 109 patients who met the criteria for FD were enrolled. Eysenck Personality Questionnaire (EPQ), Symptom Checklist 90 (SCL90), and the Pittsburgh Sleep Quality Index (PSQI) were used to measure personality, psychological symptoms, and sleep quality in our patients. Leeds Dyspepsia Questionnaire (LDQ) was used to assess dyspeptic symptoms at baseline and after eight weeks of treatment. The LDQ scores change after therapy, and the degraded rate of LDQ was used to assess the prognosis of patients...
2016: Gastroenterology Research and Practice
Ruth D H Zhou, Marcus Y L Chiu, Wing-Yip Chui
Metaphors have long been applied to marital counseling and couple therapy. This pioneering study measures marital conceptualization through metaphors. It reports the validation of the Marital Metaphor Questionnaire (MMQ-10), designed to measure the marriage conceptualization of Chinese women through marital metaphors. The MMQ-10 was found to have favorable psychometric properties including reliable internal consistency, a good discriminative prediction of marriage at risk and moderate correlation with a Chinese indigenous multidimensional marital satisfaction inventory...
July 20, 2016: Journal of Marital and Family Therapy
Meghan Campo, Hani Al-Halabi, Melin Khandekar, Alice T Shaw, Lecia V Sequist, Henning Willers
UNLABELLED: : Genotype-based selection of patients for targeted therapies has had a substantial impact on the treatment of non-small cell lung cancers (NSCLCs). Tyrosine kinase inhibitors (TKIs) directed at cancers driven by oncogenes, such as epidermal growth factor receptor mutations or anaplastic lymphoma kinase rearrangements, often achieve dramatic responses and result in prolonged survival compared with chemotherapy. However, TKI resistance invariably develops. Disease progression can be limited to only one or a few sites and might not be symptomatic, raising the important question of whether this type of oligoprogression warrants a change in systemic therapy or consideration of local treatment...
August 2016: Oncologist
Samuel Shannon, Suzanne Bartle-Harring
There is limited information on cohabiters presenting for therapy. The authors examined the characteristics of 143 married and 54 cohabiting, young (m = 30.39), Caucasian, couples presenting for therapy. We hypothesized that cohabiters presenting for therapy would be more satisfied and committed than married couples and that they would be similarly emotionally differentiated. We conducted a repeated-measures MANOVA to test the hypothesis. Significant effects between partners and between dyads were found, indicating a difference between clients based on relationship status...
June 14, 2016: Journal of Marital and Family Therapy
Fred P Piercy, Ryan M Earl, Renu K Aldrich, Hoa N Nguyen, Sarah M Steelman, Emily Haugen, Dana Riger, Ruvi T Tsokodayi, Jamie West, Yesim Keskin, Emily Gary
Marriage and family therapy educators increasingly emphasize training competencies. What we know less about is what makes family therapy education meaningful to marriage and family therapy (MFT) graduate students and what does not. In this study, through an Internet survey, we explored the most and least meaningful learning experiences of 68 MFT graduate students and recent graduates of Commission on Accreditation for Marriage and Family Therapy Education-accredited programs. We used thematic analysis to identify and illustrate resulting themes, which included the importance of experiential and personal components to learning, the professor-student alliance, tying theory to practice, and the experiences of students with their clients, among others...
June 10, 2016: Journal of Marital and Family Therapy
Rachel J Moser, Matthew L Hirsch
Recent work both at the bench and the bedside demonstrate zinc-finger nucleases (ZFNs), CRISPR/Cas9, and other programmable site-specific endonuclease technologies are being successfully utilized within and alongside AAV vectors to induce therapeutically relevant levels of directed gene editing within the human chromosome. Studies from past decades acknowledge that AAV vector genomes are enhanced substrates for homology-directed repair in the presence or absence of targeted DNA damage within the host genome...
2016: Current Gene Therapy
Rong-Liang Shi, Ning Qu, Zhong-Wu Lu, Tian Liao, Yi Gao, Qing-Hai Ji
Previous studies have revealed that marital status influences the prognosis of patients with various types of cancer. We evaluated the influence of marriage on the survival outcomes in differentiated thyroid cancer (DTC). The Surveillance, Epidemiology and End Results (SEER) database between 2002 and 2012 was used to compare cancer-specific mortality in different marital status, and in each sex, age, and stage stratification by multivariate Cox regression model. In total, 61,077 eligible patients were identified...
August 2016: Cancer Medicine
Mark Amsbaugh, Beatrice Ugiliweneza, Eric Burton, Stephen Skirboll, Shiao Woo, Max Boakye
BACKGROUND: The role of adjuvant stereotactic radiosurgery (SRS) and fractionated radiotherapy (XRT) are unknown in patients with resected meningiomas. OBJECTIVE: To identify patterns of care and outcomes of adjuvant radiotherapy for meningiomas in the Linked Surveillance, Epidemiology, and End Results (SEER) Medicare data. METHODS: A total of 1,964 patients older than 66 years included in the SEER-Medicare data, who were diagnosed with meningioma, and underwent craniotomy were included for analysis...
2016: Curēus
Samantha Backhaus, Dawn Neumann, Devan Parrot, Flora M Hammond, Claire Brownson, James Malec
BACKGROUND: Brain injury (BI) can adversely affect marriage satisfaction, which can impact rehabilitation outcomes. The objectives of this study were to (1) examine the feasibility of providing a group intervention to individuals with BI and (2) examine if improvements occur in relationship satisfaction and communication following participation. METHODS: Nine individuals with BI and their partner participated in a 16-week group intervention targeting relationship skills training...
2016: Brain Injury: [BI]
Franziska Hentzschel, Anne-Kathrin Herrmann, Ann-Kristin Mueller, Dirk Grimm
The increasing use of screening technologies in malaria research has substantially expanded our knowledge on cellular factors hijacked by the Plasmodium parasite in the infected host, including those that participate in the clinically silent liver stage. This rapid gain in our understanding of the hepatic interaction partners now requires a means to validate and further disentangle parasite-host networks in physiologically relevant liver model systems. Here, we outline seminal work that contributed to our present knowledge on the intrahepatic Plasmodium host factors, followed by a discussion of surrogate models of mammalian livers or hepatocytes...
July 2016: FEBS Letters
Stephen P H Whiteside, Brett J Deacon, Kristen Benito, Elyse Stewart
The current study examines factors related to use of exposure therapy by clinicians who treat children with anxiety disorders. A sample of 331 therapists from a variety of backgrounds (i.e., social workers, doctoral psychologists, masters level counselors, and marriage and family therapists) completed a survey regarding use of exposure and other treatment techniques for childhood anxiety disorders, as well as beliefs about exposure and child resiliency. Although the majority of therapists endorsed a CBT orientation (81%) and use of CBT techniques, exposure therapy was rarely endorsed...
May 2016: Journal of Anxiety Disorders
Ke Wang, Yu Ren, Hongyuan Li, Ke Zheng, Jun Jiang, Tianning Zou, Binlin Ma, Hui Li, Qilun Liu, Jianghua Ou, Ling Wang, Wei Wei, Jianjun He, Guosheng Ren
The incidence of young cases of breast cancer is higher in China compared to the western world. We aimed to explore differences in risk factors, clinicopathological features and treatment modes of young female breast cancer compared to older patients in West China. We collected clinical information from 12,209 female breast cancer patients in West China, including risk factors, clinicopathological features and treatment modes, from January 2010 to December 2012. Chi-square tests and the multivariate logistic regression analysis were applied for statistical analysis...
2016: PloS One
Brian D Doss, Larisa N Cicila, Emily J Georgia, McKenzie K Roddy, Kathryn M Nowlan, Lisa A Benson, Andrew Christensen
OBJECTIVE: Within the United States, one third of married couples are distressed and almost half of first marriages (and more than half of unmarried cohabiting relationships) end in divorce/separation. Additionally, relationship distress has been linked to mental and physical health problems in partners and their children. Although couple therapy is effective in reducing relationship distress, it is utilized by less than one third of divorcing couples. Therefore, more accessible interventions for relationship distress are needed...
April 2016: Journal of Consulting and Clinical Psychology
Bettina Weigelin, Elixabet Bolaños, Maria E Rodriguez-Ruiz, Ivan Martinez-Forero, Peter Friedl, Ignacio Melero
CD137(4-1BB) costimulation and adoptive T cell therapy strongly synergize in terms of achieving maximal efficacy against experimental cancers. These costimulatory biological functions of CD137 have been exploited by means of introducing the CD137 signaling domain in clinically successful chimeric antigen receptors and to more efficiently expand T cells in culture. In addition, immunomagnetic sorting of CD137-positive T cells among tumor-infiltrating lymphocytes selects for the fittest antitumor T lymphocytes for subsequent cultures...
May 2016: Cancer Immunology, Immunotherapy: CII
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