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Exclusive enteral nutrition

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https://www.readbyqxmd.com/read/28531392/a-randomised-controlled-feasibility-and-proof-of-concept-trial-in-delayed%C3%A2-gastric-emptying-when-metoclopramide-fails-we-should-revisit%C3%A2-nasointestinal-feeding-versus-dual-prokinetic-treatment-achieving-goal-nutrition-in-critical-illness-and-delayed-gastric
#1
Stephen J Taylor, Kaylee Allan, Helen McWilliam, Alex Manara, Jules Brown, Rosemary Greenwood, Deirdre Toher
BACKGROUND & AIMS: Delayed gastric emptying (DGE) commonly limits the use of enteral nutrition (EN) and may increase ventilator-associated pneumonia. Nasointestinal feeding has not been tested against dual prokinetic treatment (Metoclopramide and Erythromycin) in DGE refractory to metoclopramide. This trial tests the feasibility of recruiting this 'treatment-failed' population and the proof of concept that nasointestinal (NI) feeding can increase the amount of feed tolerated (% goal) when compared to nasogastric (NG) feeding plus metoclopramide and erythromycin treatment...
August 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28525622/dietary-therapy-with-the-crohn-s-disease-exclusion-diet-is-a-successful-strategy-for-induction-of-remission-in-children-and-adults-failing-biological-therapy
#2
Rotem Sigall Boneh, Chen Sarbagili-Shabat, Heinit Yanai, Irit Chermesh, Sivan Ben Avraham, Mona Boaz, Arie Levine
Background: Loss of response (LoR) to biologics in Crohn's disease (CD) is a significant clinical problem. Dietary therapy as a treatment strategy in this setting has not been previously reported. We report the use of dietary strategies using enteral nutrition coupled with the Crohn's Disease Exclusion Diet (CDED) for LoR to infliximab or adalimumab as a single center experience. Methods: Patients with LoR to a biologic despite dose escalation or combination therapy were treated with partial enteral nutrition (PEN) by a polymeric formula and the CDED for 12 weeks...
May 19, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28507982/the-role-of-carrageenan-and-carboxymethylcellulose-in-the-development-of-intestinal-inflammation
#3
REVIEW
John Vincent Martino, Johan Van Limbergen, Leah E Cahill
Although the exact pathophysiology remains unknown, the development of inflammatory bowel disease (IBD) is influenced by the interplay between genetics, the immune system, and environmental factors such as diet. The commonly used food additives, carrageenan and carboxymethylcellulose (CMC), are used to develop intestinal inflammation in animal models. These food additives are excluded from current dietary approaches to induce disease remission in Crohn's disease such as exclusive enteral nutrition (EEN) using a polymeric formula...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28475294/refractory-cytopenias-secondary-to-copper-deficiency-in-children-receiving-exclusive-jejunal-nutrition
#4
Amanda E Jacobson, Samir B Kahwash, Anjulika Chawla
Copper deficiency is a known cause of anemia and neutropenia that is easily remedied with copper supplementation. Copper is primarily absorbed in the stomach and proximal duodenum, so patients receiving enteral nutrition via methods that bypass this critical region may be at increased risk for copper deficiency. In pediatrics, postpyloric enteral feeding is increasingly utilized to overcome problems related to aspiration, severe reflux, poor gastric motility, and gastric outlet obstruction. However, little is known about the prevalence of copper deficiency in this population...
May 5, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28468301/the-impact-of-exclusive-enteral-nutrition-een-on-the-gut-microbiome-in-crohn-s-disease-a-review
#5
REVIEW
Amber MacLellan, Jessica Moore-Connors, Shannan Grant, Leah Cahill, Morgan G I Langille, Johan Van Limbergen
Crohn's disease (CD), a form of inflammatory bowel disease (IBD), is thought to arise from a complex interaction of genetics, the gut microbiome, and environmental factors, such as diet. There is clear evidence that dietary intervention is successful in the treatment of CD-exclusive enteral nutrition (EEN) is able to induce remission in up to 80% of CD patients. While the mechanism of action of EEN is not clear, EEN is known to cause profound changes in the gut microbiome. Understanding how EEN modifies the gut microbiome to induce remission could provide insight into CD etiopathogenesis and aid the development of microbiome-targeted interventions to guide ongoing dietary therapy to sustain remission...
May 1, 2017: Nutrients
https://www.readbyqxmd.com/read/28421777/quality-control-of-enteral-nutrition-therapy-in-cancer-patients-at-nutritional-risk
#6
Ariana Lee, Ronaldo Sousa Oliveira Filho, Thais De Campos Cardenas, Gislaine Aparecida Ozório, Juliana Pereira Lima Gropp, Dan Linetzky Waitzberg
INTRODUCTION: Quality indicators in nutritional therapy (QINTs) allow for the practical assessment of quality in the management of enteral nutrition therapy (ENT) among hospitalized patients. OBJECTIVE: To control ENT quality in cancer patients at nutritional risk. METHODS: A prospective, observational study was performed with cancer patients over 19 years of age who had undergone exclusive ENT for at least 72 h. Nutritional Risk Screening was used to assess nutritional risk; in the presence of nutritional risk, the Subjective Global Assessment (SGA) was used...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28271593/norovirus-infection-in-primary-immune-deficiency
#7
REVIEW
Li-An K Brown, Ian Clark, Julianne R Brown, Judith Breuer, David M Lowe
Norovirus is acknowledged to be a leading cause of acute gastroenteritis worldwide, and its importance as a cause of chronic infection in immune deficient hosts is increasingly recognised. Current evidence suggests that a coordinated response of innate immune mechanisms, CD8+ cytotoxicity and a humoral response, with CD4+ orchestration, is necessary for norovirus clearance. We explain how primary immune deficiency impairs these host defences and predisposes to chronic infection, associated with protracted diarrhoea, weight loss, and requirement for parenteral nutrition...
March 8, 2017: Reviews in Medical Virology
https://www.readbyqxmd.com/read/28175065/p413-exclusive-enteral-nutrition-provides-an-effective-bridge-to-safer-interval-elective-surgery-for-crohn-s-disease
#8
N Heerasing, B Thompson, P Hendy, G Heap, G Walker, R Bethune, C Calvert, N Kennedy, T Ahmad, J Goodhand
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28174932/dop007-crohn-s-disease-exclusion-diet-and-partial-enteral-nutrition-cded-pen-vs-exclusive-enteral-nutrition-een-microbiome-changes-of-a-randomized-clinical-trial-rct-in-pediatric-cd-remission-is-associated-with-similar-structural-functional-profiles
#9
K A Dunn, R Sigall-Boneh, J P Bielawski, D Turner, J Van Limbergen, A Levine
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28173089/p775-fibre-intake-is-associated-with-microbiome-changes%C3%A2-in-pediatric-crohn-s-disease-patients-following-remission-induction-with-exclusive-enteral-nutrition
#10
A MacLellan, J Connors, B MacIntyre, G Douglas, K A Dunn, J P Bielawski, A Noble, G Mahdi, M Rashid, A R Otley, L Cahill, M G Langille, J Van Limbergen
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172619/dop009-choice-of-corticosteroids-or-exclusive-enteral-nutrition-as-the-first-induction-of-remission-therapy-does-not-affect-disease-behavior-within-two-years-of-diagnosis
#11
N Cohen-Dolev, M Sladek, R Sigall Boneh, G Veres, S Hussey, A Staiano, F Nuti, P Lionetti, S Koletzko, A Levine
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172539/p612-exclusive-enteral-nutrition-in-adults-with-active-crohn-s-disease-is-associated-with-decreased-disease-activity
#12
T Pfeffer-Gik, H Yanai, L Godny, Y Ron, N Maharshak, I Dotan
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172444/dop008-dietary-manipulation-of-the-healthy-human-and-colitic-murine-gut-microbiome-by-cd-treat-diet-and-exclusive-enteral-nutrition-a-proof-of-concept-study
#13
V Svolos, R Hansen, U Z Ijaz, C Quince, D Watson, A Alghamdi, A Brejnrod, C Ansalone, S Milling, D Gaya, R Russell, K Gerasimidis
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28131521/espen-guideline-clinical-nutrition-in-inflammatory-bowel-disease
#14
Alastair Forbes, Johanna Escher, Xavier Hébuterne, Stanisław Kłęk, Zeljko Krznaric, Stéphane Schneider, Raanan Shamir, Kalina Stardelova, Nicolette Wierdsma, Anthony E Wiskin, Stephan C Bischoff
INTRODUCTION: The ESPEN guideline presents a multidisciplinary focus on clinical nutrition in inflammatory bowel disease (IBD). METHODOLOGY: The guideline is based on extensive systematic review of the literature, but relies on expert opinion when objective data were lacking or inconclusive. The conclusions and 64 recommendations have been subject to full peer review and a Delphi process in which uniformly positive responses (agree or strongly agree) were required...
April 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28114704/early-commencement-of-enteral-feeds-in-gastroschisis-a-systematic-review-of-literature
#15
Madhuri Dama, Uday Rao, Ian Gollow, Max Bulsara, Shripada Rao
Introduction There are no evidence-based strategies to improve feed tolerance in gastroschisis. Early commencement of enteral feeds (CEF) is known to improve feed tolerance in preterm infants. It is possible that infants with gastroschisis may also benefit from early CEF. Objectives To conduct a systematic review to evaluate the relationship between time of CEF, and time to reach full enteral feeds (FEF), duration of parenteral nutrition (PN), and duration of hospital stay (HS). Methods PubMed, EMBASE, Cochrane CENTRAL, and relevant conference abstracts were searched in December 2015...
January 23, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28107568/oral-immunoglobulin-treatment-improved-intestinal-permeability-in-children-with-active-crohn-s-disease
#16
Tommy Sundqvist, Lars Stenhammar, Bo Tjellström, Karl-Eric Magnusson, Tony Forslund, Lotta Högberg
AIM: Crohn's disease (CD) is a chronic mucosal inflammation that affects the intestinal barrier function, for example by altering the intestinal permeability. This pilot clinical study investigated the impact of oral human immunoglobulin (OHIG) treatment on permeability characteristics in children with active luminal Crohn's disease. METHODS: The study was performed at the Department of Paediatrics, Norrköping Hospital, Sweden. Intestinal permeability was studied in three boys aged 13, 15 and 18 years with active CD, before and after a six-week treatment programme with OHIG, using different-sized polyethylene glycols the test molecules...
January 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28105752/exclusive-enteral-nutrition-provides-an-effective-bridge-to-safer-interval-elective-surgery-for-adults-with-crohn-s-disease
#17
N Heerasing, B Thompson, P Hendy, G A Heap, G Walker, R Bethune, S Mansfield, C Calvert, N A Kennedy, T Ahmad, J R Goodhand
BACKGROUND: Few studies have reported the systematic use of exclusive enteral nutrition in the perioperative setting. AIM: To test the hypothesis that exclusive enteral nutrition provides a safe and effective bridge to surgery and reduces post-operative complications, in adult patients with Crohn's disease requiring urgent surgery for stricturing or penetrating complications. METHODS: Patients treated with exclusive enteral nutrition prior to surgery were each matched with two control patients for disease behaviour, type of surgery, age at diagnosis and disease duration...
March 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28103809/dietary-treatment-of-crohn-s-disease-perceptions-of-families-with-children-treated-by-exclusive-enteral-nutrition-a-questionnaire-survey
#18
Vaios Svolos, Konstantinos Gerasimidis, Elaine Buchanan, Lee Curtis, Vikki Garrick, Jacqueline Hay, Susan Laird, Joanna Munro, Daniel R Gaya, Richard K Russell, Richard Hansen
BACKGROUND: Diet is strongly associated with the aetiology of Crohn's Disease (CD) and exclusive enteral nutrition (EEN) is the primary induction treatment in paediatric CD. This study explored opinions around the use of EEN and alternative novel, solid food-based diets (SFDs) expressed by paediatric patients with CD, previously treated with EEN and their parents. METHODS: This anonymous questionnaire surveyed families of CD patients treated with EEN over 1 year...
January 19, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28103724/the-effect-of-polymeric-formula-on-enterocyte-differentiation
#19
Gabrielle R Budd, Alan Aitchison, Andrew S Day, Jacqueline I Keenan
Exclusive enteral nutrition is established as an initial therapy to induce remission in active Crohn's disease (CD), especially in children, but the mechanisms of action of this therapy are yet to be fully defined. Intestinal alkaline phosphatase (IAP), a recognised marker of enterocyte differentiation, is implicated in the innate gut immune response to enteric pathogens. Using the Caco-2 human adenocarcinoma cell line, this study showed that the incubation of human cells with a polymeric formula (PF) resulted in a dose-dependent increase in the expression of IAP on the cell surface...
January 1, 2017: Innate Immunity
https://www.readbyqxmd.com/read/28096129/current-knowledge-of-necrotizing-enterocolitis-in-preterm-infants-and-the-impact-of-different-types-of-enteral-nutrition-products
#20
REVIEW
Jocelyn Shulhan, Bryan Dicken, Lisa Hartling, Bodil Mk Larsen
Preterm infants are extremely vulnerable to a range of morbidities and mortality. Underdeveloped cardiac, respiratory, gastrointestinal, and immune systems in the preterm period increase the risk of necrotizing enterocolitis (NEC), a serious disease of the gut. NEC affects 5-12% of very-low birth-weight infants, leads to surgery in 20-40% of cases, and is fatal in 25-50% of cases. There are multiple factors that may contribute to NEC, but the exact cause is not yet fully understood. Severe cases can result in intestinal resection or death, and the health care costs average >$300,000/infant when surgical management is required...
January 2017: Advances in Nutrition
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