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Exclusive enteral nutrition

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https://www.readbyqxmd.com/read/29426699/perioperative-lipid-enriched-enteral-nutrition-versus-standard-care-in-patients-undergoing-elective-colorectal-surgery-sanics-ii-a-multicentre-double-blind-randomised-controlled-trial
#1
Emmeline G Peters, Boudewijn J J Smeets, Jesper Nors, Christian M Back, Jonas A Funder, Thorbjørn Sommer, Søren Laurberg, Uffe S Løve, Wouter K G Leclercq, Gerrit D Slooter, Tammo S de Vries Reilingh, Johannes A Wegdam, Grard A P Nieuwenhuijzen, Mickaël Hiligsmann, Marc P Buise, Willem A Buurman, Wouter J de Jonge, Harm J T Rutten, Misha D P Luyer
BACKGROUND: Postoperative ileus and anastomotic leakage severely impair recovery after colorectal resection. We investigated the effect of perioperative lipid-enriched enteral nutrition versus standard care on the risk of postoperative ileus, anastomotic leakage, and other clinical outcomes. METHODS: We did an international, multicentre, double-blind, randomised, controlled trial of patients (≥18 years) undergoing elective colorectal surgery with primary anastomosis at six clinical centres in the Netherlands and Denmark...
February 6, 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29413010/nutritional-interventions-in-the-patient-with-inflammatory-bowel-disease
#2
REVIEW
Berkeley N Limketkai, Andrea Wolf, Alyssa M Parian
Nutritional strategies have been explored as primary or adjunct therapies for inflammatory bowel disease (IBD). Exclusive enteral nutrition is effective for the induction of remission in Crohn disease and is recommended as a first-line therapy for children. Dietary strategies focus on adjusting the ratio of consumed nutrients that are proinflammatory or antiinflammatory. Treatments with dietary supplements focus on the antiinflammatory effects of the individual supplements (eg, curcumin, omega-3 fatty acids, vitamin D) or their positive effects on the intestinal microbiome (eg, prebiotics, probiotics)...
March 2018: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29398336/exclusive-enteral-nutrition-in-crohn-s-disease-evidence-and-practicalities
#3
REVIEW
James J Ashton, Joan Gavin, R Mark Beattie
Exclusive enteral nutrition (EEN) is the first line therapy for paediatric Crohn's disease, providing a complete nutritional feed whilst simultaneously inducing remission in up to 80% of cases. The effect of EEN on systemic/local intestinal immune function and subsequent inflammation (including barrier permeability, direct anti-inflammatory effects and cytokine signalling pathways), alongside changes in the microbiome (specific species and broad taxonomic shifts, functional changes) are becoming clearer, however the exact mechanism for induction of remission in Crohn's disease remains uncertain...
February 1, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29393903/standardized-parenteral-nutrition-for-the-transition-phase-in-preterm-infants-a-bag-that-fits
#4
Ann-Marie Brennan, Mairead E Kiely, Sarah Fenton, Brendan P Murphy
The optimal composition of standardized parenteral nutrition (SPN) is not yet known, contributing to nutrient deficit accrual and growth failure, with the period of parenteral nutrition weaning, i.e., transition (TN) phase, being identified as particularly vulnerable. We created a comprehensive nutrition database, representative of the nutritional course of a diverse range of preterm infants (n = 59, birth weight ≤ 1500 g, gestation < 34 weeks) by collecting hourly macronutrient intake data as part of a prospective, observational study over 19 months...
February 2, 2018: Nutrients
https://www.readbyqxmd.com/read/29370008/initiating-nutritional-support-before-72-hours-is-associated-with-favorable-outcome-after-severe-traumatic-brain-injury-in-children-a-secondary-analysis-of-a-randomized-controlled-trial-of-therapeutic-hypothermia
#5
Elizabeth Meinert, Michael J Bell, Sandra Buttram, Patrick M Kochanek, Goundappa K Balasubramani, Stephen R Wisniewski, P David Adelson
OBJECTIVES: To understand the relationship between the timing of initiation of nutritional support in children with severe traumatic brain injury and outcomes. DESIGN: Secondary analysis of a randomized, controlled trial of therapeutic hypothermia (Pediatric Traumatic Brain Injury Consortium: Hypothermia, also known as "the Cool Kids Trial" (NCT 00222742). SETTINGS: Fifteen clinical sites in the United States, Australia, and New Zealand. SUBJECTS: Inclusion criteria included 1) age less than 18 years, 2) postresuscitation Glasgow Coma Scale less than or equal to 8, 3) Glasgow Coma Scale motor score less than 6, and 4) available to be randomized within 6 hours after injury...
January 24, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29338698/enteral-immunonutrition-versus-enteral-nutrition-for-gastric-cancer-patients-undergoing-a-total-gastrectomy-a-systematic-review-and-meta-analysis
#6
Ying Cheng, Junfeng Zhang, Liwei Zhang, Juan Wu, Zhen Zhan
BACKGROUND: Nutrition support is a common means for patients with gastric cancer, especially for those undergoing elective surgery. Recently, enteral immunonutrition (EIN) was increasingly found to be more effective than enteral nutrition (EN) in enhancing the host immunity and eventually improving the prognosis of gastric cancer patients undergoing gastrectomy. However, the results reported were not consistent. This meta-analysis aimed to assess the impact of EIN for patients with GC on biochemical, immune indices and clinical outcomes...
January 16, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29323428/enteral-nutrition-in-the-management-of-crohn-s-disease-reviewing-mechanisms-of-actions-and-highlighting-potential-venues-for-enhancing-the-efficacy
#7
REVIEW
Moftah H Alhagamhmad
Crohn's disease (CD) is a chronic condition that affects the gut and has adverse effects on growth and development. There is a global increase in the incidence and prevalence rates, and several factors are believed to contribute to this rise, including dietary habits. In contrast, the use of enteral nutrition (EN) as an exclusive source of nutrition is increasingly becoming the preferred induction treatment of pediatric CD patients in part to address the nutrition complications. However, EN therapy is considered less effective in adults with CD...
January 11, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29316190/life-of-patients-10-years-after-a-successful-pediatric-intestinal-transplantation-in-europe
#8
Lorenzo Norsa, Girish Gupte, Esther Ramos Boluda, Francisca Joly, Olivier Corcos, Jacques Pirenne, Gustaf Herlenius, Florence Lacaille
A multicenter Europe-wide single point study in intestinal transplantation (ITx) centers was conducted to identify and describe patients surviving for more than 10 years after ITx in childhood. The health and nutritional status, care requirements and psychosocial status were recorded. Among 120 transplanted before 2005, 38 patients with a functioning graft were included. Thirty (79%) had an exclusive oral diet, 7 (18%) complimentary enteral nutrition for eating disorders, one a combination of parenteral and enteral nutrition...
January 9, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29315161/using-quality-improvement-to-increase-utilization-of-enteral-therapy-in-pediatric-crohn-disease-results-and-outcomes
#9
Ala K Shaikhkhalil, Brendan Boyle, Jennifer Smith, Jennifer L Dotson, Amy Donegan, Sandra C Kim, Ross M Maltz, Wallace Crandall
INTRODUCTION: Exclusive enteral nutrition (EEN) for induction of remission in children with Crohn's disease (CD) is recommended as first line therapy, but underutilized in the United States related to real and perceived barriers. We hypothesized that quality improvement (QI) methodology could increase use of EEN. METHODS: We developed, implemented, and revised an algorithm and a set of tools to facilitate use of EEN. Through a series of Plan Do Study Act cycles, the approach was modified to overcome provider and patient/family barriers...
January 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29310893/effect-of-fat-composition-in-enteral-nutrition-for-crohn-s-disease-in-adults-a-systematic-review
#10
REVIEW
Sarah M Ajabnoor, Alastair Forbes
BACKGROUND & AIMS: The role of enteral nutrition (EN) fat composition in regulating inflammation in Crohn's disease (CD) is not clear. There is, moreover, insufficient evidence to guide the choice of EN in CD with any confidence. We have reanalysed the findings of previous studies in a systematic review focussing on the relationship between EN fat content and remission rates (RR). METHODS: A systematic search with no language restriction was undertaken in Medline and Embase databases supplemented by a manual search in the reference lists of identified studies...
December 28, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29276586/postoperative-enterocutaneous-fistula-principles-in-non-operative-approach
#11
E A Sule, M A Nzegwu, J C Okolo, R U Onyemekheia
Introduction: Postoperative enterocutaneous fistulae could constitute a challenge when they occur following an abdominal surgery. Astute application of correct principles in its management is essential for good outcomes. Methods: A retrospective review of records of patients with enterocutaneous fistulas managed non-operatively was done. Clinical assessment, anatomic and physiologic classification of fistula, fluid resuscitation, electrolyte correction, parenteral/enteral nutrition, antibiotic use and fistula effluent monitoring, formed the basis of management...
December 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29274643/increased-efficacy-and-safety-of-enteral-nutrition-support-with-a-protocol-asnet-in-noncritical-patients-a-randomized-controlled-trial
#12
Luis Alfonso Ortíz-Reyes, Lilia Castillo-Martínez, Arianne Itzel Lupián-Angulo, Daniel Dante Yeh, Héctor Isaac Rocha-González, Aurora Elizabeth Serralde-Zúñiga
BACKGROUND: Unintentional underfeeding is common in patients receiving enteral nutrition (EN), and is associated with increased risk of malnutrition complications. Protocols for EN in critically ill patients have been shown to enhance adequacy, resulting in better clinical outcomes; however, outside of intensive care unit (ICU) settings, the influence of a protocol for EN is unknown. OBJECTIVE: To evaluate the efficacy and safety of implementing an EN protocol in a noncritical setting...
January 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29262481/-exclusive-enteral-nutrition-in-the-treatment-of-pediatric-crohn-s-disease
#13
Y Yu, J Chen
No abstract text is available yet for this article.
December 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29209542/skin-lesions-associated-with-nutritional-management-of-maple-syrup-urine-disease
#14
Jaraspong Uaariyapanichkul, Puthita Saengpanit, Ponghatai Damrongphol, Kanya Suphapeetiporn, Sirinuch Chomtho
Introduction: Maple syrup urine disease (MSUD) is an inborn error of branched chain amino acids (BCAAs) metabolism. We report an infant with MSUD who developed 2 episodes of cutaneous lesions as a result of isoleucine deficiency and zinc deficiency, respectively. Case Presentation: A 12-day-old male infant was presented with poor milk intake and lethargy. The diagnosis of MSUD was made based on clinical and biochemical data. Management and Outcome: Specific dietary restriction of BCAAs was given...
2017: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/29182898/reconnection-surgery-in-adult-post-operative-short-bowel-syndrome-100-cm-is-colonic-continuity-sufficient-to-achieve-enteral-autonomy-without-autologous-gastrointestinal-reconstruction-report-from-a-single-center-and-systematic-review-of-literature
#15
A Lauro, R Cirocchi, N Cautero, A Dazzi, D Pironi, F M Di Matteo, A Santoro, L Pironi, A D Pinna
A systematic bibliographic research concerning patients operated on for SBS was performed: inclusion criteria were adult age, reconnection surgery and SBS < 100 cm. Autologous gastrointestinal reconstruction represented an exclusion criteria. The outcomes of interest were the rate of total parenteral nutrition (TPN) independence and the length of follow-up (minimum 1 year) after surgery. We reviewed our experience from 2003 to 2013 with minimum 1-year follow-up, dealing with reconnection surgery in 13 adults affected by < 100 cm SBS after massive small bowel resection: autologous gastrointestinal reconstruction was not feasible...
July 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29173519/diet-as-a-therapeutic-option-for-adult-inflammatory-bowel-disease
#16
REVIEW
Samir Kakodkar, Ece A Mutlu
There are many mechanisms to explain how food may drive and ameliorate inflammation. Although there are no consistent macronutrient associations inflammatory bowel disease (IBD) development, many exclusion diets have been described: IgG-4 guided exclusion diet; semivegetarian diet; low-fat, fiber-limited exclusion diet; Paleolithic diet; Maker's diet; vegan diet; Life without Bread diet; exclusive enteral nutrition (EEN), the Specific Carbohydrate Diet (SCD) and the low FODMAP diet. The literature on diet and IBD is reviewed with a particular focus on EEN, SCD, and low FODMAP diets...
December 2017: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29173518/dietary-therapies-in-pediatric-inflammatory-bowel-disease-an-evolving-inflammatory-bowel-disease-paradigm
#17
REVIEW
Erin R Lane, Dale Lee, David L Suskind
Nutrition has long been recognized as a critical component in the treatment of pediatric inflammatory bowel disease (IBD). Formerly, nutritional interventions have focused on targeting improved weight gain and linear growth, as well as correction of micronutrient deficiencies. Recently, there has been growing interest and study of dietary interventions for induction and maintenance of remission. In addition to exclusive enteral nutrition, successes have been achieved with specific exclusion diets. This article evaluates current literature regarding the role of diet and nutrition in pathogenesis of disease, as well as the role of diet as primary therapy for pediatric IBD...
December 2017: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29165666/differences-in-outcomes-over-time-with-exclusive-enteral-nutrition-compared-to-steroids-in-children-with-mild-to-moderate-crohn-s-disease-results-from-the-growth-cd-study
#18
Noa Cohen-Dolev, Malgorata Sladek, Seamus Hussey, Dan Turner, Gabor Veres, Sibylle Koletzko, Javier Martin de Carpi, Annamaria Staiano, Ron Shaoul, Paolo Lionetti, Jorge Amil Dias, Anders Paerregaard, Federica Nuti, Tamar Pfeffer Gik, Tomer Ziv-Baran, Sivan Ben Avraham Shulman, Chen Sarbagili Shabat, Rotem Sigall Boneh, Richard K Russell, Arie Levine
Background: Exclusive enteral nutrition (EEN) and corticosteroids (CS) both induce similar rates of remission in mild to moderate pediatric Crohn's disease (CD), but differ with regard to mucosal healing. Our goal was to evaluate if EEN at diagnosis was superior to CS for improving long term outcomes. Methods: We prospectively followed newly diagnosed children <17 years with mild to moderate disease at baseline for two years in the GROWTH CD study. Patients were evaluated at baseline and at 8, 12, 78, and 104 weeks...
November 18, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29124070/exclusive-enteral-nutrition-induces-remission-in-pediatric-crohn-s-disease-via-modulation-of-the-gut-microbiota
#19
REVIEW
Dawei Gong, Xinjuan Yu, Lili Wang, Lingling Kong, Xiaojie Gong, Quanjiang Dong
Exclusive enteral nutrition (EEN) has been proven to be effective and safe in treating pediatric Crohn's disease (CD). EEN induces pediatric CD remission possibly through three pathways: (1) direct anti-inflammatory effects, (2) improved epithelial barrier function, and (3) modulation of the gut microbiota. Recent studies have demonstrated that modulation of the gut microbiota plays a major role in EEN-induced remission. Variations of microbial components, which directly influence the diversity and metabolic functions of the gut microbiota, are closely associated with the immunological conditions of the gut and the susceptibility to diseases...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29102418/the-utility-of-food-antigen-test-in-the-diagnosis-of-crohn-s-disease-and-remission-maintenance-after-exclusive-enteral-nutrition
#20
Gefei Wang, Jianan Ren, Guanwei Li, Qiongyuan Hu, Guosheng Gu, Huajian Ren, Zhiwu Hong, Jieshou Li
BACKGROUND: Crohn's disease (CD) involves intensive immunologic responses to food antigens. Exclusive enteral nutrition (EEN) showed efficacy in inducing disease remission. However, relapse commonly occurred when normal diet was reintroduced. We aimed to investigate the food-specific IgG antibodies of CD, and clarify the effects of exclusion diet guided by food-specific antibodies on remission maintenance after EEN. METHODS: All available data of food-specific antibodies were retrieved from the database and analyzed for the diagnostic value...
October 25, 2017: Clinics and Research in Hepatology and Gastroenterology
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