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Exclusive enteral nutrition

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https://www.readbyqxmd.com/read/29903605/a-retrospective-evaluation-of-nutrition-support-in-relation-to-clinical-outcomes-in-critically-ill-patients-with-an-open-abdomen
#1
Rosalie Yandell, Susan Wang, Peter Bautz, Alison Shanks, Stephanie O'Connor, Adam Deane, Kylie Lange, Marianne Chapman
BACKGROUND: Optimising nutrition support in critically ill patients with an open abdomen is challenging. OBJECTIVES: The aims of this study were to (i) quantify the amount and adequacy of nutrition support administered and (ii) determine any relationships that exist between mode of nutrition support delivery and clinical outcomes in critically ill patients with an open abdomen. METHODS: A retrospective review of critically ill patients mechanically ventilated for at least 48 h with an open abdomen in a mixed quaternary referral intensive care unit...
June 11, 2018: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29901086/exclusive-enteral-nutrition-protects-against-inflammatory-bowel-disease-by-inhibiting-nf%C3%A2-%C3%AE%C2%BAb-activation-through-regulation-of-the-p38-msk1-pathway
#2
Ting Yu, Qian Yu, Xiaotian Chen, Lixing Zhou, Yuming Wang, Chenggong Yu
Although enteral nutrition therapy for inflammatory bowel disease has been confirmed to be an effective treatment method, the exact mechanism responsible for the effects of enteral nutrition remains unclear. The aim of the present study was to investigate the protective effect of exclusive enteral nutrition (EEN) against colitis, and to elucidate the potential mechanisms by inhibiting p65 activation via regulating the p38/mitogen‑ and stress‑activated protein kinase‑1 (MSK1) pathway. Experiments were performed by establishing dextran sulfate sodium (DSS)‑mice colitis and picrylsulfonic acid solution (TNBS)‑induced rat colitis, and the results demonstrated that EEN treatment attenuated body weight loss, colon length shortening and colonic pathological damage caused by colitis...
June 4, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29886499/the-impact-of-preoperative-enteral-nutrition-enriched-with-eicosapentaenoic-acid-on-postoperative-hypercytokinemia-after-pancreatoduodenectomy-the-results-of-a-double-blinded-randomized-controlled-trial
#3
Ryo Ashida, Yukiyasu Okamura, Kanako Wakabayashi-Nakao, Takashi Mizuno, Shuichi Aoki, Katsuhiko Uesaka
AIMS: To investigate whether preoperative enteral diets -enriched in eicosapentaenoic acid (EPA) supplements could reduce the incidence of hypercytokinemia after pancreatoduodenectomy (PD) in a double-blinded randomized -controlled trial. METHODS: Patients with resectable periampullary cancer were randomized into either the control group or the treatment group. Patients in the treatment group received oral supplementation (600 kcal/day) containing EPA for 7 days before surgery...
June 8, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29849179/efficacy-predictors-of-a-2-month-exclusive-enteral-nutrition-for-inducing-remission-of-active-crohn-s-disease
#4
Meng Xue, Hanyun Zhang, Xiaoying Wang, Dingting Xu, Dan Jin, Peiwei Li, Jun Ye, Qiao Yu, Yan Chen
In order to identify the factors that could predict the efficacy of exclusive enteral nutrition (EEN) in inducing remission of active CD. Baseline clinical and laboratory covariates were correlated with the outcome (clinical remission) of EEN in active CD (CDAI ≥150) by both univariable and multivariable analyses. A total of 67 from a consecutive of 136 active CD patients were enrolled. L4b (from treitz ligament to distal 1/3 ileum) involvement was negatively and high serum albumin (≥35 g/L) was positively associated with clinical remission (OR: 0...
May 30, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29843419/standard-polymeric-formula-tube-feeding-in-neurologically-impaired-children-a-five-year-retrospective-study
#5
Valeria Dipasquale, Maria Ausilia Catena, Sabrina Cardile, Claudio Romano
Malnutrition is frequent in neurologically impaired (NI) children. Enteral feeding via gastrostomy tube is increasingly being used to provide adequate nutrition. Our aim was to assess the outcomes of exclusive gastrostomy tube feeding with standard polymeric formula in children with NI, severe oro-motor dysfunction, and malnutrition, and to investigate the role of the underlying NI-associated disease. A five-year retrospective study from January 2013 to November 2017 was conducted. The primary aim was to assess the nutritional outcomes of exclusive gastrostomy tube feeding with standard polymeric formula in malnourished NI children...
May 28, 2018: Nutrients
https://www.readbyqxmd.com/read/29777041/evolving-role-of-diet-in-the-pathogenesis-and-treatment-of-inflammatory-bowel-diseases
#6
REVIEW
Arie Levine, Rotem Sigall Boneh, Eytan Wine
Recent advances in basic and clinical science over the last 3 years have dramatically altered our appreciation of the role of diet in inflammatory bowel diseases (IBD). The marked increase in incidence of these diseases along with the important role of non-genetic susceptibility among patients with IBD has highlighted that these diseases have a strong environmental component. Progress in the field of microbiome and IBD has demonstrated that microbiome appears to play an important role in pathogenesis, and that diet may in turn impact the composition and functionality of the microbiome...
May 18, 2018: Gut
https://www.readbyqxmd.com/read/29766816/a-systematic-review-of-the-literature-of-the-three-related-disease-entities-cheilitis-granulomatosa-orofacial-granulomatosis-and-melkersson-rosenthal-syndrome
#7
Goetz Wehl, Markus Rauchenzauner
BACKGROUND AND OBJECTIVE: Melkersson Rosenthal syndrome (MRS) is a rare disorder of unknown etiology and comprises the triad: orofacial edema, recurrent facial paralysis and lingua plicata. In the current literature confusing heterogeneity exists, mixing together the historically grown terms cheilitis granulomatosa or granulomatous cheilitis, Melkersson Rosenthal syndrome and the umbrella term orofacial granulomatosis (OFG). METHODS: We provide a systematic review comprising all three disease entities of orofacial granulomatosis using the computerized database "Pubmed Medline" entering the key words "orofacial granulomatosis" (141 references), "Melkersson-Rosenthal syndrome" (207 references), "granulomatous cheilitis" or "cheilitis granulomatosa" (102 references) back to 1956...
May 14, 2018: Current Pediatric Reviews
https://www.readbyqxmd.com/read/29756986/-dietetic-treatment-with-fructose-in-a-5-year-old-girl-with-recurrent-d-lactic-acidosis
#8
Lourdes Travieso Suárez, Pilar Quijada Fraile, Consuelo Pedrón Giner
D-lactic acidosis is an infrequent complication, mainly reported in patients with short bowel syndrome. It is characterized by recurrent episodes of encephalopathy with elevated serum D-lactic acid, usually associating metabolic acidosis. The presence of D-lactate-producing bacteria is necessary for the development of this complication. Other factors, such as the ingestion of large amounts of carbohydrates or reduced intestinal motility, contribute to D-lactic acidosis. We report a case of recurrent D-lactic acidosis in a 5-year-old girl with short bowel syndrome, due to a midgut volvulus...
March 1, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29730900/strategies-for-the-enhancement-of-nutrition-practice-in-a-new-york-state-level-1-trauma-center-a-hospital-s-journey
#9
Lisa Musillo, Laryssa Marie Grguric, Edward Coffield, Frank Aversano, Jeremy Bosworth, Richard Batista
BACKGROUND: Provision of enteral nutrition (EN) support is historically inadequate in the critically ill population. An interdisciplinary approach utilizing various strategies has been shown to improve initiation of timely EN support. The purpose of this study was to examine whether the implementation of a series of interventions led by an interdisciplinary team was associated with changes in the initiation of nutrition support in a level 1 trauma center. METHODS: Patients admitted between 2009 and 2013 with isolated closed head trauma injuries were identified through the hospital's trauma center database...
December 18, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29713622/nutritional-care-in-iranian-intensive-care-units
#10
Maryam Shabanpur, Seyed Mostafa Nachvak, Shima Moradi, Safora Hedayati, Mahboobe Hosseinikia, Yahya Pasdar, Shahrbanoo Gholizadeh, Mehnoosh Samadi
Intensive care units (ICUs) provides intensive treatment medicine to avoid complications such as malnutrition, infection and even death. As very little is currently known about the nutritional practices in Iranian ICUs, this study attempted to assess the various aspects of current nutrition support practices in Iranian ICUs. We conducted a cross-sectional study on 150 critically ill patients at 18 ICUs in 12 hospitals located in 2 provinces of Iran from February 2015 to March 2016. Data were collected through interview with supervisors of ICUs, medical record reviews and direct observation of patients during feeding...
April 2018: Clinical Nutrition Research
https://www.readbyqxmd.com/read/29701656/enteral-nutrition-in-the-management-of-pediatric-and-adult-crohn-s-disease
#11
REVIEW
Tawnya Hansen, Donald R Duerksen
Genetic and environmental factors are thought to profoundly influence the pathophysiology of Crohn’s disease (CD). Changes in dietary and hygiene patterns affect the interactions between the immune system and environment. The gut microbiome is responsible for mediating host immune response with significant dysbiosis observed in individuals with CD. Diet therapy using exclusive enteral nutrition (EEN) has been studied as primary therapy for the management of CD. EEN may cultivate the presence of beneficial microbiota, improve bile acid metabolism, and decrease the number of dietary microparticles possibly influencing disease and immune activity...
April 26, 2018: Nutrients
https://www.readbyqxmd.com/read/29607496/enteral-nutritional-therapy-for-induction-of-remission-in-crohn-s-disease
#12
REVIEW
Neeraj Narula, Amit Dhillon, Dongni Zhang, Mary E Sherlock, Melody Tondeur, Mary Zachos
BACKGROUND: Corticosteroids are often preferred over enteral nutrition (EN) as induction therapy for Crohn's disease (CD). Prior meta-analyses suggest that corticosteroids are superior to EN for induction of remission in CD. Treatment failures in EN trials are often due to poor compliance, with dropouts frequently due to poor acceptance of a nasogastric tube and unpalatable formulations. This systematic review is an update of a previously published Cochrane review. OBJECTIVES: To evaluate the effectiveness and safety of exclusive EN as primary therapy to induce remission in CD and to examine the importance of formula composition on effectiveness...
April 1, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29565144/resolution-of-control-and-monitoring-instrument-of-nutritional-therapy-in-the-intensive-care-unit-of-a-university-hospital
#13
Bianca Abreu Dos Santos de Oliveira, Elenir Rose Jardim Cury Pontes, Teresa Cristina Abranches Rosa
INTRODUCTION: Patients in intensive care status are in nutritional threat and frequently present innutrition, therefore monitoring the nutritional offer becomes indispensable. AIM: To purpose a control and monitoring form of enteral nutritional therapy and to evaluate its resoluteness. METHODS: Observational, analytical and retrospective study performed in intensive care patients receiving an enteral diet exclusively and/or associated with the oral/parenteral route, from January to April 2015 and from January to April 2016...
January 10, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29543696/global-variation-in-use-of-enteral-nutrition-for-pediatric-crohn-disease
#14
Morgan Lawley, Jessica W Wu, Victor M Navas-López, Hien Q Huynh, Matthew W Carroll, Min Chen, Pavel Medvedev, Andrew S Day, Séamus Hussey, Rotem Sigall-Boneh, Arie Levine, Eytan Wine
OBJECTIVES: Exclusive enteral nutrition (EEN) is an effective induction treatment for pediatric Crohn disease. Given the center-based variation in use and diversity in practice we constructed a survey aimed at sharing experience and strategies in administering EEN, stimulating further research, and optimizing therapy. METHODS: This survey was constructed after consultation with experts and designed to address key knowledge gaps. The survey was disseminated through the Paediatric IBD Porto Group of ESPGHAN, Canadian Children IBD Network, selective experts, and was sent twice through the PEDGI-BB...
March 14, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29499978/evaluation-of-implementation-of-fasting-guidelines-for-enterally-fed-critical-care-patients
#15
Bethan Jenkins, Philip C Calder, Luise V Marino
BACKGROUND & AIMS: Critically ill adults have increased nutrition risk. Prior to procedures patients are often fasted, leading to nutritional deficits. The use of fasting guidelines may therefore help reduce deficits from accumulating. The aim of this work was to determine the impact on nutrition support delivery following the implementation of fasting guidelines in addition to characterizing staff knowledge of the guidelines. DESIGN: Retrospective data were collected on n = 74 patients at two different time points; prior to launch of fasting guidelines and post launch, with regards to estimated nutritional requirements, nutritional targets, volume of enteral nutrition (EN) delivered and periods of fasting...
February 15, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29426699/perioperative-lipid-enriched-enteral-nutrition-versus-standard-care-in-patients-undergoing-elective-colorectal-surgery-sanics-ii-a-multicentre-double-blind-randomised-controlled-trial
#16
Emmeline G Peters, Boudewijn J J Smeets, Jesper Nors, Christian M Back, Jonas A Funder, Thorbjørn Sommer, Søren Laurberg, Uffe S Løve, Wouter K G Leclercq, Gerrit D Slooter, Tammo S de Vries Reilingh, Johannes A Wegdam, Grard A P Nieuwenhuijzen, Mickaël Hiligsmann, Marc P Buise, Willem A Buurman, Wouter J de Jonge, Harm J T Rutten, Misha D P Luyer
BACKGROUND: Postoperative ileus and anastomotic leakage severely impair recovery after colorectal resection. We investigated the effect of perioperative lipid-enriched enteral nutrition versus standard care on the risk of postoperative ileus, anastomotic leakage, and other clinical outcomes. METHODS: We did an international, multicentre, double-blind, randomised, controlled trial of patients (≥18 years) undergoing elective colorectal surgery with primary anastomosis at six clinical centres in the Netherlands and Denmark...
April 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29413010/nutritional-interventions-in-the-patient-with-inflammatory-bowel-disease
#17
REVIEW
Berkeley N Limketkai, Andrea Wolf, Alyssa M Parian
Nutritional strategies have been explored as primary or adjunct therapies for inflammatory bowel disease (IBD). Exclusive enteral nutrition is effective for the induction of remission in Crohn disease and is recommended as a first-line therapy for children. Dietary strategies focus on adjusting the ratio of consumed nutrients that are proinflammatory or antiinflammatory. Treatments with dietary supplements focus on the antiinflammatory effects of the individual supplements (eg, curcumin, omega-3 fatty acids, vitamin D) or their positive effects on the intestinal microbiome (eg, prebiotics, probiotics)...
March 2018: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29398336/exclusive-enteral-nutrition-in-crohn-s-disease-evidence-and-practicalities
#18
REVIEW
James J Ashton, Joan Gavin, R Mark Beattie
Exclusive enteral nutrition (EEN) is the first line therapy for paediatric Crohn's disease, providing a complete nutritional feed whilst simultaneously inducing remission in up to 80% of cases. The effect of EEN on systemic/local intestinal immune function and subsequent inflammation (including barrier permeability, direct anti-inflammatory effects and cytokine signalling pathways), alongside changes in the microbiome (specific species and broad taxonomic shifts, functional changes) are becoming clearer, however the exact mechanism for induction of remission in Crohn's disease remains uncertain...
February 1, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29393903/standardized-parenteral-nutrition-for-the-transition-phase-in-preterm-infants-a-bag-that-fits
#19
Ann-Marie Brennan, Mairead E Kiely, Sarah Fenton, Brendan P Murphy
The optimal composition of standardized parenteral nutrition (SPN) is not yet known, contributing to nutrient deficit accrual and growth failure, with the period of parenteral nutrition weaning, i.e., transition (TN) phase, being identified as particularly vulnerable. We created a comprehensive nutrition database, representative of the nutritional course of a diverse range of preterm infants ( n = 59, birth weight ≤ 1500 g, gestation < 34 weeks) by collecting hourly macronutrient intake data as part of a prospective, observational study over 19 months...
February 2, 2018: Nutrients
https://www.readbyqxmd.com/read/29370008/initiating-nutritional-support-before-72-hours-is-associated-with-favorable-outcome-after-severe-traumatic-brain-injury-in-children-a-secondary-analysis-of-a-randomized-controlled-trial-of-therapeutic-hypothermia
#20
Elizabeth Meinert, Michael J Bell, Sandra Buttram, Patrick M Kochanek, Goundappa K Balasubramani, Stephen R Wisniewski, P David Adelson
OBJECTIVES: To understand the relationship between the timing of initiation of nutritional support in children with severe traumatic brain injury and outcomes. DESIGN: Secondary analysis of a randomized, controlled trial of therapeutic hypothermia (Pediatric Traumatic Brain Injury Consortium: Hypothermia, also known as "the Cool Kids Trial" (NCT 00222742). SETTINGS: Fifteen clinical sites in the United States, Australia, and New Zealand...
April 2018: Pediatric Critical Care Medicine
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