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https://www.readbyqxmd.com/read/29449869/off-label-prescription-of-psychiatric-drugs-by-non-psychiatrist-physicians-in-three-general-hospitals-in-germany
#1
Caroline Lücke, Jürgen M Gschossmann, Teja W Grömer, Sebastian Moeller, Charlotte E Schneider, Aikaterini Zikidi, Alexandra Philipsen, Helge H O Müller
Background: Off-label prescribing of psychoactive drugs is a common practice in psychiatry. Here, we sought to investigate the frequency of off-label prescribing in a population of hospitalized patients with a somatic illness who were also suffering from a psychiatric pathology. Methods: Using a prospective, observational design, we collected data from 982 hospitalized patients with a somatic illness for whom a psychiatric consultation was requested because of the presence of additional psychiatric symptoms...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29449789/factors-associated-with-prescribing-costs-analysis-of-a-nationwide-administrative-database
#2
O Hirsch, M Schulz, M Erhart, N Donner-Banzhoff
Objective: All health care systems in the world struggle with rising costs for drugs. We sought to explore factors impacting on prescribing costs in a nationwide database of ambulatory care in Germany. Factors identified by this research can be used for adjustment in future profiling efforts. Methods: We analysed nationwide prescription data of physicians having contractual relationships with statutory health insurance funds in 2014. Predictor and outcome variables were aggregated at the practice level...
2018: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/29427409/utilization-of-antiepileptic-medicines-in-swedish-children-and-adolescents-with-different-diagnoses
#3
Linnéa Karlsson Lind, Katarina Wide, Björn Wettermark, Mia von Euler
This study aimed to investigate the utilization of antiepileptic drugs (AEDs) in children and adolescents with epilepsy and other diagnoses in a nationwide population between 2007 and 2014. Data on dispensed prescriptions of AEDs were collected from the Swedish Prescribed Drug Register and linked to diagnosis data from the National Patient Register covering all in- and outpatient consultations from Swedish hospitals. Children aged 0-17 years who had received at least one prescription for AEDs were selected...
February 10, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29427050/transcranial-magnetic-stimulation-tms-in-the-elderly
#4
REVIEW
Ilva G Iriarte, Mark S George
PURPOSE OF REVIEW: This article aims to review select applications of Transcranial Magnetic Stimulation (TMS) that have significant relevance in geriatric psychiatry. RECENT FINDINGS: Small study sizes and parameter variability limit the generalizability of many TMS studies in geriatric patients. Additionally, geriatric patients have unique characteristics that can moderate the efficacy of TMS. Nonetheless, several promising experimental applications in addition to the FDA-approved indication for major depression have emerged...
February 10, 2018: Current Psychiatry Reports
https://www.readbyqxmd.com/read/29416240/intensive-care-unit-delirium-a-wide-gap-between-actual-prevalence-and-psychiatric-referral
#5
Sandeep Grover, Siddharth Sarkar, Lakshmi Narayana Yaddanapudi, Abhishek Ghosh, Amit Desouza, Debasish Basu
Background and Aims: The study aimed to assess the rates of delirium in an Intensive Care Unit (ICU) prospectively assessed with a delirium screening instrument and confirmed through psychiatrist evaluation. In addition, the referral rate to psychiatric consultation liaison services from the same ICU was assessed through the rates of psychiatric referral over the previous 10 years. Material and Methods: In the prospective part of the study, consecutive patients aged 16 years or more admitted to the ICU of a tertiary care hospital were assessed daily for delirium using confusion assessment method for the ICU, a validated instrument that can be used for both mechanically ventilated and nonventilated patient by trained heath care personnel...
October 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/29412850/electroconvulsive-therapy-in-geriatric-psychiatry-a-selective-review
#6
REVIEW
Justin P Meyer, Samantha K Swetter, Charles H Kellner
Electroconvulsive therapy (ECT) remains an important treatment of geriatric patients. ECT treats severe depression, mania, psychosis, catatonia, and comorbid depression and agitation in dementia. ECT also serves a crucial role in treating urgent illness requiring expedient recovery, such as catatonia, or in patients with severe suicidal ideation or intent. ECT is even more effective in the elderly than in mixed-age adult populations. ECT is a safe treatment option with few medical contraindications. Cognitive effects are largely transient, even in patients with preexisting cognitive impairment...
March 2018: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/29412847/advances-in-the-conceptualization-and-study-of-schizophrenia-in-later-life
#7
REVIEW
Carl I Cohen, Ksenia Freeman, Dina Ghoneim, Aninditha Vengassery, Brian Ghezelaiagh, Michael M Reinhardt
A crisis looms as research and clinical programs have not kept pace with dramatic increases in the number of older adults with schizophrenia. This article provides an overview of the advances in the conceptualization and study of schizophrenia in later life. Theoretic and clinical models in psychiatry and gerontology are integrated. Specifically, recovery is examined in the context of aging, how clinical dimensionality affects diagnoses in older adults, how various features of schizophrenia are implicated in models of accelerated and paradoxic aging, and how outcome in later life is a more dynamic and heterogeneous than assumed previously...
March 2018: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/29407722/validation-of-the-spanish-and-catalan-versions-of-the-health-of-the-nation-outcome-scale-for-children-and-adolescents-honosca
#8
Anna Ballesteros-Urpí, Héctor Pardo-Hernández, Andreu Ferrero-Gregori, Jordi Torralbas-Ortega, Joaquim Puntí-Vidal, Pere Tàpies Olivet, Jon Izaguirre Eguren, Pere Vergés Balasch, Anaís Lara Lloveras, Santiago Bertomeu, Montserrat Peramiquel, Victoria Herreros, Àngela Vidal, Elena Font, Soledad Romero, Marta Garcia, Luisa Lázaro, Àstrid Morer
Outcome measurement in outpatient and day-care mental health facilities for children and adolescents in Spain remains limited, in part due to a lack of validated scales. To address this issue, we translated HoNOSCA (glossary, score sheet, self-rated questionnaire, and parent/legal guardian questionnaire) into Spanish and Catalan using a reverse translation approach. We ascertained the validity and psychometric quality of the HoNOSCA in Spanish by assessing correlation with the Children's Global Assessment Scale (C-GAS)...
December 21, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29407543/natural-speech-algorithm-applied-to-baseline-interview-data-can-predict-which-patients-will-respond-to-psilocybin-for-treatment-resistant-depression
#9
Facundo Carrillo, Mariano Sigman, Diego Fernández Slezak, Philip Ashton, Lily Fitzgerald, Jack Stroud, David J Nutt, Robin L Carhart-Harris
BACKGROUND: Natural speech analytics has seen some improvements over recent years, and this has opened a window for objective and quantitative diagnosis in psychiatry. Here, we used a machine learning algorithm applied to natural speech to ask whether language properties measured before psilocybin for treatment-resistant can predict for which patients it will be effective and for which it will not. METHODS: A baseline autobiographical memory interview was conducted and transcribed...
January 29, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29405756/age-neutrality-of-a-brief-assessment-of-the-section-iii-alternative-model-for-personality-disorders-in-older-adults
#10
Inge Debast, Gina Rossi, S P J van Alphen
The alternative model for personality disorders in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders ( DSM-5) is considered an important step toward a possibly better conceptualization of personality pathology in older adulthood, by the introduction of levels of personality functioning (Criterion A) and trait dimensions (Criterion B). Our main aim was to examine age-neutrality of the Short Form of the Severity Indices of Personality Problems (SIPP-SF; Criterion A) and Personality Inventory for DSM-5-Brief Form (PID-5-BF; Criterion B)...
February 1, 2018: Assessment
https://www.readbyqxmd.com/read/29404198/sleep-quality-perceived-stress-and-caffeinated-drinks-intake-in-psychiatry-residents-a-cross-sectional-study
#11
Carmen Concerto, Claudio Conti, Maria R Muscatello, Maria S Signorelli, Rocco Zoccali, Diego Coira, Eugenio Aguglia, Fortunato Battaglia
Background: Medical residencies are highly demanding and stressful and have been associated with mental and emotional problems. Studies that evaluated this relationship in Italian psychiatry residents are scarce. In this study, we examined sleep quality and its association with perceived stress and caffeinated beverages consumption in Italian psychiatry residents. Methods: Seventy-two PGY1-5 psychiatry residents at two University Hospitals in Italy were asked to complete an anonymous questionnaire. The Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale were used to determine the sleep quality and the level of daytime sleepiness (EDS)...
March 1, 2017: Journal of Caffeine Research
https://www.readbyqxmd.com/read/29392601/school-refusal-behavior-in-indian-children-analysis-of-clinical-profile-psychopathology-and-development-of-a-best-fit-risk-assessment-model
#12
Ajita Nayak, Bijal Sangoi, Hrishikesh Nachane
OBJECTIVES: School refusal is seen as an emergency in child psychiatry and various risk factors have been analyzed. Children who present with school refusal have been shown to have several associated psychiatric comorbidities. However, risk assessment of psychiatric comorbidities is lacking, particularly in the Indian context. The authors aimed to study the sociodemographic profile and associated psychopathology in children with school refusal. They compared the prevalence rates of psychiatric illnesses to that of the community...
February 1, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29389697/pharmacotherapy-for-primary-delusional-jealousy-a-retrospective-observational-study-of-32-cases-with-othello-syndrome
#13
Chen-Chung Liu, Yen-Chin Wang, Tzung-Jeng Hwang
To determine whether primary delusional jealousy can be treated effectively with antipsychotics or antidepressants, and whether any clinical variables are associated with response to pharmacotherapy, we carried out a retrospective case series observational study by reviewing clinical records of patients with an International Classification of Disease, 9th ed., diagnostic code of 297 (delusional disorders) who were treated at the Department of Psychiatry of a university affiliated hospital from January 2010 to December 2015...
March 2018: International Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29388185/the-association-of-a-number-of-risk-factors-with-depression-in-patients-with-prostate-cancer-undergoing-androgen-deprivation-therapy
#14
Chang Hee Kim, Kwang Teack Kim, Jin Kyu Oh, Kyung Jin Chung, Tae Beom Kim, Han Jung, Sang Jin Yoon, Khae Hawn Kim
PURPOSE: To identify factors affecting depressive symptoms in patients undergoing androgen-deprivation therapy (ADT) to treat prostate cancer. MATERIALS AND METHODS: The patients with prostate cancer visiting the psychiatry department without referral because of depressive symptoms while undergoing ADT participated. To assess depressive symptoms, the Beck Depression Inventory (BDI) was used. To identify the risk factors affecting depressive symptoms, univariate regression and multiple linear regression analyses were implemented...
February 1, 2018: Urology Journal
https://www.readbyqxmd.com/read/29381388/long-acting-injectable-atypical-antipsychotic-use-in-adolescents-an-observational-study
#15
Adriana Fortea, Daniel Ilzarbe, Laura Espinosa, Mireia Solerdelcoll, Clara de Castro, Giovanni Oriolo, Gisela Sugranyes, Inmaculada Baeza
OBJECTIVES: Although second generation long-acting injectable antipsychotics (SG-LAIAs) have been approved and are widely used in adults, there is limited evidence for the use of long-acting formulations in children and adolescents. Thus, we systematically describe the off-label use of SG-LAIAs in clinical practice in adolescent inpatients. METHODS: All individuals admitted to our Children and Adolescent Inpatient Psychiatry Unit receiving treatment with SG-LAIAs between January 2013 and June 2016 were reviewed...
January 30, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29368239/ethical-legal-and-forensic-issues-in-geriatric-psychiatry
#16
REVIEW
Rajesh R Tampi, Juan Young, Silpa Balachandran, Dhweeja Dasarathy, Deena Tampi
PURPOSE OF THE REVIEW: To evaluate the ethical, legal and forensic issues that is faced by the older adult population. RECENT FINDINGS: Many older individuals will face a host of ethical, medical and legal issues associated with their care. Most prominent among these issues are the maintenance of autonomy while ensuring their safety and the safety of individuals who care for them. Decisions regarding end of life including the formulation of advance directives add to the complexity of care for these older adults...
January 25, 2018: Current Psychiatry Reports
https://www.readbyqxmd.com/read/29353178/impulsivity-in-early-psychosis-a-complex-link-with-violent-behaviour-and-a-target-for-intervention
#17
V Moulin, P Golay, J Palix, P S Baumann, M-M Gholamrezaee, A Azzola, J Gasser, K Q Do, L Alameda, P Conus
BACKGROUND: Violent behaviour (VB) occurs in first episode of schizophrenia and can have devastating impact both on victims and patients themselves. A better knowledge of the underlying mechanisms of VB may pave the way to preventive treatments. OBJECTIVES: 1) To explore the nature of the link between impulsivity and VB in early psychosis (EP) patients; 2) To explore the interactions between impulsivity and substance abuse, insight, and positive symptoms, the main dynamic risk factors of VB described to date...
January 17, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29348292/morbid-jealousy-reactivated-by-mood-episodes
#18
Ruziana Masiran, Nik Shaliza Hussin
A middle-aged man who has been enduring financial constraint experienced a period of irritability, increased goal-directed activities and insomnia occurring along with extreme jealousy with his current wife. The episode was followed by depressed mood and non-prominent auditory hallucination. His previous history revealed a forensic psychiatry case of a murder he committed 20 years ago.
January 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29339664/cenesthopathy-and-subjective-cognitive-complaints-an-exploratory-study-in-schizophrenia
#19
Natalia Jimeno, Martin L Vargas
BACKGROUND/AIMS: Cenesthopathy is mainly associated with schizophrenia; however, its neurobiological basis is nowadays unclear. The general objective was to explore clinical correlates of cenesthopathy and subjective cognitive complaints in schizophrenia. METHODS: Participants (n = 30) meeting DSM-IV criteria for psychotic disorder were recruited from a psychiatry unit and assessed with: Association for Methodology and Documentation in Psychiatry (AMDP) system, Positive and Negative Syndrome Scale, Frankfurt Complaint Questionnaire (FCQ), and the Bonn Scale for the Assessment of Basic Symptoms (BSABS)...
January 16, 2018: Psychopathology
https://www.readbyqxmd.com/read/29321707/validity-and-reliability-of-the-turkish-version-for-dsm-5-level-2-anger-scale-child-form-for-children-aged-11-17-years-and-parent-form-for-children-aged-6-17-years
#20
Şermin Yalin Sapmaz, Handan Özek Erkuran, Nefize Yalin, Özlem Önen, Siğnem Öztekin, Canem Kavurma, Ertuğrul Köroğlu, Ömer Aydemir
Introduction: This study aimed to assess the validity and reliability of the Turkish version of Diagnostic and Statistical Manual of Mental Disorders (DSM-5) Level 2 Anger Scale. Methods: The scale was prepared by translation and back translation of DSM-5 Level 2 Anger Scale. Study groups consisted of a clinical sample of cases diagnosed with depressive disorder and treated in a child and adolescent psychiatry unit and a community sample. The study was continued with 218 children and 160 parents...
December 2017: Noro Psikiyatri Arsivi
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