Samira Filali, Nesrine Darragi-Raies, Layth Ben-Trad, Agnès Piednoir, Saw-See Hong, Fabrice Pirot, Ahmed Landoulsi, Agnès Girard-Egrot, Thierry Granjon, Ofelia Maniti, Pierre Miossec, Ana-Maria Trunfio-Sfarghiu
The morphology of fibroblast-like synoviocytes (FLS) issued from the synovial fluid (SF) of patients suffering from osteoarthritis (OA), rheumatoid arthritis (RA), or from healthy subjects (H), as well as the ultrastructure and mechanical properties of the FLS-secreted extracellular vesicles (EV), were analyzed by confocal microscopy, transmission electron microscopy, atomic force microscopy, and tribological tests. EV released under healthy conditions were constituted of several lipid bilayers surrounding a viscous inner core...
October 30, 2022: International Journal of Molecular Sciences