Ayşen Işık, Ulviye Acar Çevik, Arzu Karayel, Iqrar Ahmad, Harun Patel, İsmail Çelik, Ülküye Dudu Gül, Gizem Bayazıt, Hayrani Eren Bostancı, Ahmet Koçak, Yusuf Özkay, Zafer Asım Kaplancıklı
In this study, a series of new benzimidazole-thiadiazole hybrids were synthesized, and the synthesized compounds were screened for their antimicrobial activities against eight species of pathogenic bacteria and three fungal species. Azithromycin, voriconazole, and fluconazole were used as reference drugs in the mtt assay. Among them, compounds 5f and 5h showed potent antifungal activity against C. albicans with a MIC of 3.90 μg/mL. Further, the results of the antimicrobial assay for compounds 5a , 5b , 5f , and 5h proved to be potent against E...
April 23, 2024: ACS Omega