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paraphenylenediamine

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https://www.readbyqxmd.com/read/27819696/sensitization-to-occupational-allergens-in-hairdressing-apprentices-diagnosed-already-before-entering-vocational-training
#1
Aleksandra Golińska-Zach, Patrycja Krawczyk-Szulc, Marta Wiszniewska, Ewa Nowakowska-Świrta, Dominika Świerczyńska-Machura, Diana Tymoszuk, Jolanta Walusiak-Skorupa
BACKGROUND: Hairdressers are occupationally exposed to many allergenic and irritating substances. Additionally, hairdressing apprentices are exposed to the same allergens as professional hairdressers, due to the fact that vocational training starts in the beginning of the education. This study was undertaken to investigate early occurrence of sensitization to occupational allergens in hairdressing apprentices before the onset of the vocational training. MATERIAL AND METHODS: Three hundred and seven hairdressing apprentices were assessed using a questionnaire and skin prick tests (SPTs) to common and occupational allergens...
2016: Medycyna Pracy
https://www.readbyqxmd.com/read/27770109/the-application-of-paraphenylenediamine-staining-for-assessment-of-phospholipidosis
#2
Norimitsu Shirai, Frank J Geoly, Walter F Bobrowski, Carlin Okerberg
Drug-induced phospholipidosis is characterized by intracellular accumulation of phospholipids with lamellar bodies in cells exposed to xenobiotics. Demonstration of the lamellar bodies by transmission electron microscopy (TEM) is the hallmark for a definitive diagnosis of phospholipidosis. However, the preparation of tissue samples for TEM and their ultrastructural evaluation are technically challenging and time consuming. Paraphenylenediamine (PPD) is essentially a fat stain, and the staining mechanism is based upon the osmication of unsaturated lipids...
October 21, 2016: Toxicologic Pathology
https://www.readbyqxmd.com/read/27226405/automated-axon-counting-in-rodent-optic-nerve-sections-with-axonj
#3
Kasra Zarei, Todd E Scheetz, Mark Christopher, Kathy Miller, Adam Hedberg-Buenz, Anamika Tandon, Michael G Anderson, John H Fingert, Michael David Abràmoff
We have developed a publicly available tool, AxonJ, which quantifies the axons in optic nerve sections of rodents stained with paraphenylenediamine (PPD). In this study, we compare AxonJ's performance to human experts on 100x and 40x images of optic nerve sections obtained from multiple strains of mice, including mice with defects relevant to glaucoma. AxonJ produced reliable axon counts with high sensitivity of 0.959 and high precision of 0.907, high repeatability of 0.95 when compared to a gold-standard of manual assessments and high correlation of 0...
May 26, 2016: Scientific Reports
https://www.readbyqxmd.com/read/26852369/allergic-contact-dermatitis-due-to-cosmetics-a-clinical-and-epidemiological-study-in-a-tertiary-hospital
#4
V Zaragoza-Ninet, R Blasco Encinas, J J Vilata-Corell, A Pérez-Ferriols, C Sierra-Talamantes, A Esteve-Martínez, J de la Cuadra-Oyanguren
The incidence of allergic contact dermatitis (ACD) to cosmetics in the general population is rising with the increasing use of cosmetic products and their proliferation and diversification. The aims of this study were to determine the prevalence of ACD to cosmetics in our setting, analyze changes over time, describe the clinical and epidemiological features of this allergic reaction, and identify the allergens and cosmetics involved. We performed a prospective study at the skin allergy unit in Hospital General Universitario de Valencia in Spain between 2005 and 2013 and compared our findings with data collected retrospectively for the period 1996 to 2004...
May 2016: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/26663148/skin-testing-of-gallic-acid-based-hair-dye-in-paraphenylenediamine-paratoluenediamine-reactive-patients
#5
Yunseok Choi, Joon Ho Lee, Hyok Bu Kwon, Susun An, Ai-Young Lee
Incidence of allergic contact dermatitis (ACD) to para-phenylenediamine (PPD)/paratoluenediamine (PTD) hair dyes is increasing. Hair dyes utilizing gallic acid (GA) may be a safe alternative. However, pretesting is recommended. We investigated the contact sensitivity to ingredients of a dye product; GA, monoethanolamine thioglycolate (MT), l-cystein and ferrous sulfate, and an appropriate pretest method in 31 patients reactive to PPD and/or PTD. An open test was performed with the test dye following the patch test...
July 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/26285898/-not-available
#6
M Worm, U Lippert, J Geier, A Schnuch
Allergic contact eczema in children is frequent. If clinically suspected, a patch test should be performed. In the present study, data obtained from 116,742 patients who had undergone a patch test from 2005-2014 were analysed. The children group (range 0-12 years) included 925 patients. If at least 700 tested individuals were considered, the most frequent sensitizations in this group were nickel sulfate (8.5 %), fragrance mix I (5.5 %), and colophony (3.4 %), whereby sensitisation in adults was higher for nickel sulfate (15...
September 2015: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/26251063/exposure-of-hairdressers-to-aromatic-diamines-an-interventional-study-confirming-the-protective-effect-of-adequate-glove-use
#7
Tom Geens, Evelyne Aerts, Marc Borguet, Vincent Haufroid, Lode Godderis
OBJECTIVES: Many hairdressers leave their profession due to health problems, including occupational hand eczema, which has been associated with skin exposure to sensitising hair dye components such as paraphenylenediamine (PPD) and paratoluenediamine (PTD). Since the use of protective gloves is advised but without the short-term effect being known, our main goal was to attribute a significant biomarker reduction to adequate glove use, in a real work situation. METHODS: 11 hairdressers were studied over 2 weeks...
April 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/26223015/involvement-of-cathepsin-b-in-mitochondrial-apoptosis-by-p-phenylenediamine-under-ambient-uv-radiation
#8
Shruti Goyal, Saroj Kumar Amar, Divya Dubey, Manish Kumar Pal, Jyoti Singh, Ankit Verma, Hari Narayan Kushwaha, Ratan Singh Ray
Paraphenylenediamine (PPD), a derivative of paranitroaniline has been most commonly used as an ingredient of oxidative hair dye and permanent tattoos. We have studied the phototoxic potential of PPD under ambient ultraviolet radiation. PPD is photodegraded and form a novel photoproduct under UV A exposure. PPD shows a concentration dependent decrease in cell viability of human Keratinocyte cells (HaCaT) through MTT and NRU test. Significant intracellular ROS generation was measured by DCFDA assay. It caused an oxidative DNA damage via single stranded DNA breaks, micronuclei and CPD formation...
December 30, 2015: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/26120183/erythema-multiforme-like-secondary-to-paraphenylenediamine-due-to-henna-tattoo-plus-residual-hypopigmentation
#9
Cristian Fischer Levancini, Maribel Iglesias Sancho, Vicente Exposito Serrano, Eulalia Baselga Torres
Temporary henna tattoos or pseudotattoos have become increasingly widespread among children and adolescent. A generalized skin reaction, type erythema multiforme-like reaction is unusual, and rarely reported. We describe the case of a 7-year-old boy who reported erythematous papular bull's-eye shaped lesions and consolidated edema primarily in the upper and lower extremities. These lesions were compatibles with erythema multiforme-like reaction. He also showed an erythematous-eczematous lesion on his leg, shaped like a dolphin...
May 2015: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/26067431/the-anti-aging-protein-klotho-enhances-remyelination-following-cuprizone-induced-demyelination
#10
Ella Zeldich, Ci-Di Chen, Robin Avila, Satish Medicetty, Carmela R Abraham
The current study examined whether overexpression of Klotho (KL) in transgenic mice can enhance remyelination following cuprizone-induced demyelination and improves the clinical outcome in experimental autoimmune encephalomyelitis (EAE). Demyelination was achieved by feeding transgenic mice overexpressing the transmembrane form of Klotho (KL-OE) and wild-type (WT) littermates cuprizone-containing chow for 6 weeks. The animals were then allowed to remyelinate for 3 weeks. Paraphenylenediamine staining and platelets-derived growth factor receptor α (PDGFRα) and glutathione S-transferase pi (GSTpi) immunohistochemistry were performed on corpus callosum (CC) sections for quantification of myelin and progenitor and mature oligodendrocytes, respectively...
October 2015: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/26056768/paraphenylenediamine-containing-hair-dye-an-emerging-household-poisoning
#11
Ambika Prasad Patra, Kusa Kumar Shaha, Anand P Rayamane, Shreemanta Kumar Dash, Manoj Kumar Mohanty, Sachidananda Mohanty
Paraphenylenediamine poisoning is among one of the emerging causes of poisoning in Asian countries, because it is a constituent of hair dye formulations and is easily available in market at low cost. Hair dyes are rampantly used in Asian households compared with the western world. Locally, hair dye constituents may have allergic adverse effects, and acute systemic poisoning presents with characteristic angioedema, upper airway obstruction, rhabdomyolysis, methemoglobinemia, myoglobinuria, and acute renal failure...
September 2015: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/25954688/evaluation-of-suspected-cosmetic-induced-facial-dermatoses-with-the-use-of-indian-standard-series-and-cosmetic-series-patch-test
#12
Madhur Kant Rastogi, Astha Gupta, Puneet Singh Soodan, Nitin Mishra, Pratik Gahalaut
INTRODUCTION: Awareness about skin beauty or cosmetic elegance has received worldwide attention in the present day youth oriented society. Along with careful detailed history and thorough examination patch test is considered cornerstone in diagnosis of allergic contact dermatitis. MATERIALS AND METHODS: Fifty patients suspected clinical diagnosis of contact facial dermatitis due to attended the Department of Dermatology, were included in a hospital based study. The patch test was applied on the upper back of using 32 allergens present in Indian cosmetic series and 20 known allergens in Indian standard battery series procured from Systopic Pharmaceutical Ltd, after applying the patch test, the patient was asked to come after 48h and 72h for reading the results of the patch test...
March 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/25846501/human-systemic-exposure-to-%C3%A2-%C3%A2-c-paraphenylenediamine-containing-oxidative-hair-dyes-absorption-kinetics-metabolism-excretion-and-safety-assessment
#13
Gerhard J Nohynek, Julie A Skare, Wim J A Meuling, Kenneth R Wehmeyer, Albertus Th H J de Bie, Wouter H J Vaes, Eric K Dufour, Rolf Fautz, Winfried Steiling, Mario Bramante, Herve Toutain
Systemic exposure was measured in humans after hair dyeing with oxidative hair dyes containing 2.0% (A) or 1.0% (B) [(14)C]-p-phenylenediamine (PPD). Hair was dyed, rinsed, dried, clipped and shaved; blood and urine samples were collected for 48 hours after application. [(14)C] was measured in all materials, rinsing water, hair, plasma, urine and skin strips. Plasma and urine were also analysed by HLPC/MS/MS for PPD and its metabolites (B). Total mean recovery of radioactivity was 94.30% (A) or 96.21% (B). Mean plasma Cmax values were 132...
July 2015: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/25775668/photo-developer-allergic-contact-dermatitis-in-a-photographer-following-paraphenylenediamine-sensitization-from-a-temporary-henna-tattoo
#14
Tiffany Chen, Melanie D Pratt
BACKGROUND: Paraphenylenediamine (PPD) is a coloring agent and potent sensitizer commonly added to henna tattoos to darken tattoo color. Photographic developers contain compounds that cross-react with PPD. Allergic contact dermatitis (ACD) from photo developers has been documented in the literature. OBJECTIVE: We describe the rare case of a photographer who presented with a 4-year history of recurrent ACD following exposure to photochemicals. History taking revealed that 10 years before presentation, he had received a temporary henna tattoo...
January 2015: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/25773411/paraphenylenediamine-in-black-henna-temporary-tattoos-12-year-food-and-drug-administration-data-on-incidence-symptoms-and-outcomes
#15
EDITORIAL
Alina Goldenberg, Sharon E Jacob
No abstract text is available yet for this article.
April 2015: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/25697619/-reaction-to-a-black-henna-tattoo-treated-with-mometasone-furoate-and-silicone-gel-case-report
#16
Carlos Manuel Aboitiz-Rivera, Ruben Blachman-Braun, Laura Graciela Ferrer-Arellano
UNLABELLED: Black henna tattoos have paraphenylenediamine (PPD), which contains a product of herbal origin, which due to its molecular characteristics is capable of inducing, in susceptible individuals, a type IV hypersensitivity reaction. It clinically manifests as a contact dermatitis that usually when it disappears, scarring and hypopigmentation are left in the injured area. OBJECTIVE: To describe the case of a patient with hypersensitivity to henna tattoo and to present the most relevant phenomena associated with this condition...
December 2014: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/25395929/eosinophilic-cellulitis-wells-syndrome-caused-by-a-temporary-henna-tattoo
#17
Hikmet Tekin Nacaroglu, Mehmet Celegen, Canan Sule Unsal Karkıner, Ilker Günay, Güllden Diniz, Demet Can
Eosinophilic cellulitis (Wells' syndrome) is an uncommon condition of unknown etiology. Wells' syndrome is usually seen in adulthood but very rare in childhood. Although pathogenesis of the disease is not very clear, it is a hypersensitivity reaction developing against a variety of exogenous and endogenous antigenic stimuli. Paraphenylenediamine is a strong allergen frequently used as a temporary henna tattoo, which makes the color darker. Here, a 9-year-old male patient with Wells' syndrome is presented, which developed following a temporary henna tattoo and shown by the patch test sensitivity to paraphenylenediamine...
October 2014: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/25071293/paraphenylenediamine-induced-cutaneous-pseudolymphoma
#18
Fiona F Sequeira, Elizabeth Jayaseelan, John Stephen
No abstract text is available yet for this article.
July 2014: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/24702872/hair-dyes-and-temporary-tattoos-are-a-real-hazard-for-adolescents
#19
H Haluk Akar, S Adatepe, F Tahan, I Solmaz
Temporary tattoos, especially those that contain black dyes, have become rampant among teenagers in recent years. Most of these tattoos, in addition to hair dyes include paraphenylenediamine (PPD). PPD is a well-known skin sensitizer, which causes allergic contact dermatitis. Allergic contact dermatitis skin lesions from PPD are mostly seen as erythema multiforme-like eruption, a bullous contact dermatitis or as an exudative erythema. Herein, we report on our finding on a 15 year-old adolescent female who had been unaware of being previously sensitized to PPD from a black henna tattoo, and angioedema-like reaction which occurred after her first exposure to hair dye...
January 2014: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/24686800/severe-facial-swelling-in-a-pregnant-woman-after-using-hair-dye
#20
Michel E van Genderen, Ginette Carels, Edward R Lonnee, Adriaan Dees
A 33-year-old Caucasian pregnant woman (26 weeks' gestation) presented to the emergency department. She had a 2-day history of severe itching of the scalp and steadily worsening swelling of the face over the previous 12 h, which had extended to the neck. She had no difficulty breathing. The itching and swelling had developed 3 days after she had used hair dye. The patient had no history of allergic responses to hair dye or black henna tattoos. A diagnosis of type IV delayed hypersensitivity reaction was made...
2014: BMJ Case Reports
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