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https://www.readbyqxmd.com/read/28203288/nebivolol-versus-other-beta-blockers-in-patients-with-hypertension-and-erectile-dysfunction
#1
REVIEW
Randall P Sharp, Barry J Gales
Erectile dysfunction (ED) impacts over 100 million men worldwide and occurs at a higher incidence in men with hypertension. Beta blockers are one of several antihypertensive drug classes associated with ED. Nebivolol is a beta blocker with vasodilating properties mediated through endothelial release of nitric oxide which facilitates penile erection. Thus, nebivolol may offer an advantage over other beta blockers in the patient with hypertension and ED. A literature search comparing nebivolol with other beta blockers identified four European studies of limited duration, with the longest study being 28 weeks...
February 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/28165796/crohn-s-disease-for-the-general-physician-management
#2
J J Barlow, A B Hawthorne
Crohn's disease presents to general physicians in a variety of ways. The previous article outlined clinical features and initial investigations, and this article covers management of Crohn's disease, including monitoring and drug toxicity.
February 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28165787/crohn-s-disease-for-the-general-physician-presentation-and-investigations
#3
J J Barlow, A B Hawthorne
Crohn's disease presents to general physicians in a variety of ways. This article outlines the clinical features and initial investigation of suspected Crohn's disease. The accompanying article reviews treatment strategies.
February 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28161628/application-of-biochar-and-nitrogen-influences-fluxes-of-co2-ch4-and-n2o-in-a-forest-soil
#4
Iain Hawthorne, Mark S Johnson, Rachhpal S Jassal, T Andrew Black, Nicholas J Grant, Sean M Smukler
Nitrogen (N) fertilization of forests for increasing carbon sequestration and wood volume is expected to influence soil greenhouse gas (GHG) emissions, especially to increase N2O emissions. As biochar application is known to affect soil GHG emissions, we investigated the effect of biochar application, with and without N fertilization, to a forest soil on GHG emissions in a controlled laboratory study. We found that biochar application at high (10%) application rates increased CO2 and N2O emissions when applied without urea-N fertilizer...
February 2, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28150984/a-century-of-work-teams-in-the-journal-of-applied-psychology
#5
John E Mathieu, John R Hollenbeck, Daan van Knippenberg, Daniel R Ilgen
Work groups are a vital link between individuals and organizations. Systematic psychological research on the nature and effects of work groups dates back at least to the Hawthorne studies of the 1920s and 1930s. Yet little to none of this work appeared in the Journal of Applied Psychology until the 1950s when groups were treated primarily as foils against which to compare the performance of individuals. From the 1990s to the present, the volume of research and the nature of topics addressing work group/teams expanded significantly...
February 2, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28133369/functional-foods-and-dietary-supplements-for-the-management-of-dyslipidaemia
#6
REVIEW
Paola M Hunter, Robert A Hegele
Dyslipidaemia is characterized by increased blood levels of total or LDL cholesterol and triglycerides, or decreased HDL cholesterol levels, and is a risk factor for cardiovascular disease. Dyslipidaemia has a high worldwide prevalence, and many patients are turning to alternatives to pharmacotherapy to manage their lipid levels. Lifestyle modification should be emphasized in all patients to reduce cardiovascular risk and can be initiated before pharmacotherapy in primary prevention of cardiovascular disease...
January 30, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28120718/nutraceuticals-and-dietary-supplements-to-improve-quality-of-life-and-outcomes-in-heart-failure-patients
#7
Arrigo Fg Cicero, Alessandro Colletti
BACKGROUND: Heart failure (HF) is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill or eject blood. It represents a major public health issue, with a prevalence of over 23 million worldwide. The lifetime risk of developing HF is one in five and the most important risk factors identified are ischemic heart disease, hypertension, smoking, obesity and diabetes. Preventive approaches are based on improvements of lifestyle, associated with pharmacological therapy...
January 24, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28119096/hawthorn-crataegus-pinnatifida-bunge-leave-flavonoids-attenuate-atherosclerosis-development-in-apoe-knock-out-mice
#8
Pengzhi Dong, Lanlan Pan, Xiting Zhang, Wenwen Zhang, Xue Wang, Meixiu Jiang, Yuanli Chen, Yajun Duan, Honghua Wu, Yantong Xu, Peng Zhang, Yan Zhu
ETHNOPHARMACOLOGICAL RELEVANCE: Hawthorn (Crataegus pinnatifida Bunge) leave have been used to treat cardiovascular diseases in China and Europe. Hawthorn leave flavonoids (HLF) are the main part of extraction. Whether hawthorn leave flavonoids could attenuate the development of atherosclerosis and the possible mechanism remain unknown. MATERIALS AND METHODS: High-fat diet (HFD) mixed with HLF at concentrations of 5mg/kg and 20mg/kg were administered to apolipoprotein E (apoE) knock out mice...
January 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28118318/the-authors-reply
#9
Sara Shahrestani, Paul Robertson, Henry Claud Capron Pleass, Wayne John Hawthorne
No abstract text is available yet for this article.
February 2017: Transplantation
https://www.readbyqxmd.com/read/28078623/identification-of-host-fruit-volatiles-from-snowberry-symphoricarpos-albus-attractive-to-rhagoletis-zephyria-flies-from-the-western-united-states
#10
Dong H Cha, Shannon B Olsson, Wee L Yee, Robert B Goughnour, Glen R Hood, Monte Mattsson, Dietmar Schwarz, Jeffrey L Feder, Charles E Linn
A mixture of behaviorally active volatiles was identified from the fruit of snowberry, Symphoricarpos albus laevigatus, for Rhagoletis zephyria flies reared from snowberry fruit. A nine-component blend containing 3-methylbutan-1-ol (3%), dimethyl trisulfide (1%), 1-octen-3-ol (40%), myrcene (8%), nonanal (9%), linalool (13%), (3E)-4,8-dimethyl-1,3,7-nonatriene (DMNT, 6%), decanal (15%), and β-caryophyllene (5%) was identified that gave consistent electroantennogram activity and was behaviorally active in flight tunnel tests...
January 11, 2017: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/28026705/a-screening-mechanism-to-recognize-and-support-at-risk-aboriginal-children
#11
Nancy L Young, Diane Jacko, Mary Jo Wabano, Lauren Hawthorne, Sarah Seabrook, Sheri Wabanosse, Koyo Usuba
OBJECTIVES: The Aboriginal Children's Health and Well-Being Measure© (ACHWM) was developed to assess health from the perspectives of Aboriginal children. The purpose of this paper is to document the screening process, embedded within the ACHWM, and assess its effectiveness. METHODS: The ACHWM was implemented in 2014/2015 with children 8 to 18 years of age living on the Wiikwemkoong Unceded Territory. Survey responses were screened to identify potential risk, using an automated algorithm run on computer tablets...
December 27, 2016: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28025124/major-triterpenoids-in-chinese-hawthorn-crataegus-pinnatifida-and-their-effects-on-cell-proliferation-and-apoptosis-induction-in-mda-mb-231-cancer-cells
#12
Lingrong Wen, Ruixue Guo, Lijun You, Arshad Mehmood Abbasi, Tong Li, Xiong Fu, Rui Hai Liu
The cytotoxicity and antiproliferative effect of phytochemicals presenting in the fruits of Chinese hawthorn (Crataegus pinnatifida) were evaluated. Shanlihong (Crataegus pinnatifida Bge. var. major N.E.Br.) variety possessed significant levels of flavonoids and triterpenoids, and showed potent antiproliferative effect against HepG2, MCF-7 and MDA-MB- 231 human cancer cells lines. Triterpenoids-enriched fraction (S9) prepared by Semi-preparative HPLC, and its predominant ingredient ursolic acid (UA) demonstrated remarkably antiproliferative activities for all the tested cancer cell lines...
February 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28024451/weathering-in-soil-increases-nanoparticle-cuo-bioaccumulation-within-a-terrestrial-food-chain
#13
Alia D Servin, Luca Pagano, Hiram Castillo-Michel, Roberto De la Torre-Roche, Joseph Hawthorne, Jose A Hernandez-Viezcas, René Loredo-Portales, Sanghamitra Majumdar, Jorge Gardea-Torresday, Om Parkash Dhankher, Jason C White
This study evaluates the bioaccumulation of unweathered (U) and weathered (W) CuO in NP, bulk and ionic form (0-400 mg/kg) by lettuce exposed for 70 d in soil co-contaminated with field incurred chlordane. To evaluate CuO trophic transfer, leaves were fed to crickets (Acheta domestica) for 15 d, followed by insect feeding to lizards (Anolis carolinensis). Upon weathering, the root Cu content of the NP treatment increased 214% (327 ± 59.1 mg/kg) over unaged treatment. Cu root content decreased in bulk and ionic treatments from 70-130 mg/kg to 13-26 mg/kg upon aging in soil...
January 9, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28006832/the-dual-edema-preventing-molecular-mechanism-of-the-crataegus-extract-ws-1442-can-be-assigned-to-distinct-phytochemical-fractions
#14
Simone Fuchs, Iris Bischoff, Elisabeth A Willer, Jacqueline Bräutigam, Martin F Bubik, Clemens A J Erdelmeier, Egon Koch, Maria T Faleschini, Maria De Mieri, Milena Bauhart, Stefan Zahler, Andreas Hensel, Matthias Hamburger, Olivier Potterat, Robert Fürst
The hawthorn (Crataegus spp.) extract WS 1442 is used against mild forms of chronic heart failure. This disease is associated with endothelial barrier dysfunction and edema formation. We have recently shown that WS 1442 protects against this dysfunction by a dual mechanism: it both promotes endothelial barrier integrity by activation of a barrier-enhancing pathway (cortactin activation) and inhibits endothelial hyperpermeability by blocking a barrier disruptive pathway (calcium signaling). In this study, we aimed to identify the bioactive compounds responsible for these actions by using a bioactivity-guided fractionation approach...
December 22, 2016: Planta Medica
https://www.readbyqxmd.com/read/28003447/sensory-specificity-and-speciation-a-potential-neuronal-pathway-for-host-fruit-odour-discrimination-in-rhagoletis-pomonella
#15
Cheyenne Tait, Srishti Batra, Sree Subha Ramaswamy, Jeffrey L Feder, Shannon B Olsson
Behavioural changes in habitat or mate choice can trigger population divergence, leading to speciation. However, little is known about the neurological bases for such changes. Rhagoletis pomonella (Diptera: Tephritidae) is a model for ecological speciation via host plant shifts. Within the past 180 years, Rhagoletis flies infesting hawthorn (Crataegus spp.) shifted to attack domesticated apple (Malus pumila). The two populations differ in their olfactory preferences for apple versus hawthorn fruit. Here, we looked for patterns of sensory organization that may have contributed to this shift by characterizing the morphology, specificity and distribution of olfactory sensory neurons (OSNs) on the antennae of Rhagoletis responding to host fruit and non-host volatiles...
December 28, 2016: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/27990565/characterization-of-apple-stem-grooving-virus-and-apple-chlorotic-leaf-spot-virus-identified-in-a-crab-apple-tree
#16
Yongqiang Li, Congliang Deng, Yong Bian, Xiaoli Zhao, Qi Zhou
Apple stem grooving virus (ASGV), apple chlorotic leaf spot virus (ACLSV), and prunus necrotic ringspot virus (PNRSV) were identified in a crab apple tree by small RNA deep sequencing. The complete genome sequence of ACLSV isolate BJ (ACLSV-BJ) was 7554 nucleotides and shared 67.0%-83.0% nucleotide sequence identity with other ACLSV isolates. A phylogenetic tree based on the complete genome sequence of all available ACLSV isolates showed that ACLSV-BJ clustered with the isolates SY01 from hawthorn, MO5 from apple, and JB, KMS and YH from pear...
December 18, 2016: Archives of Virology
https://www.readbyqxmd.com/read/27990181/risk-of-cerebral-embolization-with-caseous-calcification-of-the-mitral-annulus-review-article
#17
Charles A Dietl, Christopher M Hawthorn, Veena Raizada
BACKGROUND: Caseous calcification of the mitral annulus (CCMA) is believed to have a benign prognosis. Several authors have recommended conservative management in asymptomatic patients. However, the prevalence of cerebrovascular events (CVE) in patients with CCMA has never been evaluated before. The aims of this study are to investigate whether patients with CCMA are at increased risk of cerebral embolization, and to determine whether elective surgical resection of CCMA should be considered to prevent a cardioembolic stroke...
2016: Open Cardiovascular Medicine Journal
https://www.readbyqxmd.com/read/27976230/melatonin-and-selenium-content-in-dried-white-mulberry-leaves-hawthorn-inflorescences-and-multiherbal-blends-used-as-functional-dietary-supplements
#18
G Bazylak, M Siepak, A Przybylska, A Gryn, B Sperkowska
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27942216/a-novel-herbal-treatment-reduces-depressive-like-behaviors-and-increases-brain-derived-neurotrophic-factor-levels-in-the-brain-of-type-2-diabetic-rats
#19
Chun Luo, Yuting Ke, Yanyan Yuan, Ming Zhao, Fuyan Wang, Yisheng Zhang, Shizhong Bu
BACKGROUND: Radix Puerariae and hawthorn fruit have been demonstrated to treat diabetes. They offer potential benefits for preventing depression in diabetes. OBJECTIVE: The aim of this study was to investigate whether the combination of Radix Puerariae and hawthorn fruit (CRPHF) could prevent depression in a diabetic rat model generated by feeding the rats with a high-fat diet and a low-dose streptozotocin (STZ). METHODS: The CRPHF was provided by the Shanghai Chinese Traditional Medical University...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27930706/do-reported-effects-of-acute-aerobic-exercise-on-subsequent-higher-cognitive-performances-remain-if-tested-against-an-instructed-self-myofascial-release-training-control-group-a-randomized-controlled-trial
#20
Max Oberste, Wilhelm Bloch, Sven T Hübner, Philipp Zimmer
A substantial body of evidence suggests positive effects of acute aerobic exercise (AAE) on subsequent higher cognitive functions in healthy young adults. These effects are widely understood as a result of the ongoing physiological adaptation processes induced by the preceding AAE. However, designs of published studies do not control for placebo, Hawthorne and subject expectancy effects. Therefore, these studies do not, at a high degree of validity, allow attributing effects of AEE on subsequent cognitive performance to exercise induced physical arousal...
2016: PloS One
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