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https://www.readbyqxmd.com/read/29665452/utility-of-glycated-hemoglobin-screening-in-patients-undergoing-elective-coronary-artery-surgery-prospective-cohort-study-from-the-e-cabg-registry
#1
Francesco Nicolini, Giuseppe Santarpino, Giuseppe Gatti, Daniel Reichart, Francesco Onorati, Giuseppe Faggian, Magnus Dalén, Sorosh Khodabandeh, Theodor Fischlein, Daniele Maselli, Saverio Nardella, Antonino S Rubino, Marisa De Feo, Antonio Salsano, Riccardo Gherli, Giovanni Mariscalco, Eeva-Maija Kinnunen, Vito G Ruggieri, Karl Bounader, Matteo Saccocci, Sidney Chocron, Juhani Airaksinen, Andrea Perrotti, Fausto Biancari
BACKGROUND: Patients with increased glycated hemoglobin (HbA1c) seem to be at increased risk of sternal wound infection (SWI) after coronary artery bypass grafting (CABG). However, it is unclear whether increased baseline HbA1c levels may affect other postoperative outcomes. MATERIAL AND METHODS: Data on preoperative levels of HbA1c were collected from 2606 patients undergoing elective isolated CABG from 2015 to 2016 and included in the prospective, multicenter E-CABG registry...
April 14, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29664893/occupational-exposure-during-emergency-department-thoracotomy-a-prospective-multi-institution-study
#2
Andrew Nunn, Priya Prakash, Kenji Inaba, Alvarez Escalante, Zoë Maher, Seiji Yamaguchi, Dennis Y Kim, James Maciel, William C Chiu, Byron Drumheller, Joshua P Hazelton, Kaushik Mukherjee, Xian Luo-Owen, Rachel M Nygaard, Ashley P Marek, Bryan C Morse, Caitlin A Fitzgerald, Patrick L Bosarge, Randeep S Jawa, Susan E Rowell, Louis J Magnotti, Adrian W Ong, Tejal S Brahmbhatt, Michael D Grossman, Mark J Seamon
BACKGROUND: Occupational exposure is an important consideration during emergency department thoracotomy (EDT). While HIV/hepatitis prevalence in trauma patients (0-16.8%) and occupational exposure rates during operative trauma procedures (1.9-18.0%) have been reported, exposure risk during EDT is unknown. We hypothesized that occupational exposure risk during EDT would be greater than other operative trauma procedures. METHODS: A prospective, observational study at 16 US trauma centers was performed (2015-2016)...
April 16, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29662886/high-prevalence-of-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-among-clinical-isolates-from-cats-and-dogs-admitted-to-a-veterinary-hospital-in-switzerland
#3
Anna Lena Zogg, Sabrina Simmen, Katrin Zurfluh, Roger Stephan, Sarah N Schmitt, Magdalena Nüesch-Inderbinen
Objectives: This study aimed to identify and characterize extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae among clinical samples of companion animals. Methods: A total of 346 non-duplicate Enterobacteriaceae isolates were collected between 2012 and 2016 from diseased cats ( n  = 115) and dogs ( n  = 231). The presence of bla ESBL , PMQR genes, and the azithromycin resistance gene mph(A) was confirmed by PCR and sequencing of bla genes...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29644052/environmental-colonization-and-onward-clonal-transmission-of-carbapenem-resistant-acinetobacter-baumannii-crab-in-a-medical-intensive-care-unit-the-case-for-environmental-hygiene
#4
Deborah H L Ng, Kalisvar Marimuthu, Jia Jun Lee, Wei Xin Khong, Oon Tek Ng, Wei Zhang, Bee Fong Poh, Pooja Rao, Maya Devi Rajinder Raj, Brenda Ang, Partha Pratim De
Background: In May 2015, we noticed an increase in carbapenem-resistant Acinetobacter baumannii (CRAB) infections in the Medical Intensive Care Unit (MICU). To investigate this, we studied the extent of environmental contamination and subsequent onward clonal transmission of CRAB. Methods: We conducted a one-day point prevalence screening (PPS) of the patients and environment in the MICU. We screened patients using endotracheal tube aspirates and swabs from nares, axillae, groin, rectum, wounds, and exit sites of drains...
2018: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29619662/knockdown-of-sox2-inhibits-os-cells-invasion-and-migration-via-modulating-wnt-%C3%AE-catenin-signaling-pathway
#5
Liang Tang, Dong Wang, Dongyun Gu
Osteosarcoma (OS) was a prevalent malignant bone tumor which threatens people's health worldwide. Wnt/β catenin signaling pathway had been proved significant in various cancers, indicating its possible function in OS as well. Sox2, a crucial member among SOX family could regulate cells biologically. How Sox2 modulated Wnt/β catenin signaling pathway in OS remained to be discussed. The study aimed to investigate the effects of Sox2 on the invasion and migration of OS cells and the related molecular mechanisms...
April 4, 2018: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/29618775/in-vivo-study-of-non-invasive-effects-of-non-thermal-plasma-in-pressure-ulcer-treatment
#6
Maedeh Chatraie, Giti Torkaman, Mohammadreza Khani, Hossein Salehi, Babak Shokri
According to high incidence and prevalence of pressure ulcers worldwide, the purpose of this study is using of non-thermal atmospheric plasma as a novel therapy for pressure ulcers. Cold plasma was produced by applying a high-voltage (5 kV) and high-frequency (25 kHz), to helium gas. Under general anesthesia and sterile conditions, two circular magnets were used to create pressure ulcers on the dorsal skin of adult rats. The wounds were divided randomly into control and plasma-treated groups. Animals in the plasma-treated group received plasma radiation for 5 days, each day 3 times and every time 60 s...
April 4, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29617780/perceived-quality-of-in-service-communication-and-counseling-among-adolescents-undergoing-voluntary-medical-male-circumcision
#7
Lynn M Van Lith, Elizabeth C Mallalieu, Eshan U Patel, Kim H Dam, Michelle R Kaufman, Karin Hatzold, Arik V Marcell, Webster Mavhu, Catherine Kahabuka, Lusanda Mahlasela, Emmanuel Njeuhmeli, Kim Seifert Ahanda, Getrude Ncube, Gissenge Lija, Collen Bonnecwe, Aaron A R Tobian
Background: Experience with providers shapes the quality of adolescent health services, including voluntary medical male circumcision (VMMC). This study examined the perceived quality of in-service communication and counseling during adolescent VMMC services. Methods: A postprocedure quantitative survey measuring overall satisfaction, comfort, perceived quality of in-service communication and counseling, and perceived quality of facility-level factors was administered across 14 VMMC sites in South Africa, Tanzania, and Zimbabwe...
April 3, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29617779/parental-communication-engagement-and-support-during-the-adolescent-voluntary-medical-male-circumcision-experience
#8
Kim H Dam, Michelle R Kaufman, Eshan U Patel, Lynn M Van Lith, Karin Hatzold, Arik V Marcell, Webster Mavhu, Catherine Kahabuka, Lusanda Mahlasela, Emmanuel Njeuhmeli, Kim Seifert Ahanda, Getrude Ncube, Gissenge Lija, Collen Bonnecwe, Aaron A R Tobian
Background: Voluntary medical male circumcision (VMMC) is one of few opportunities in sub-Saharan Africa to engage male adolescents in the healthcare system. Limited data are available on the level of parental communication, engagement, and support adolescents receive during the VMMC experience. Methods: We conducted 24 focus group discussions with parents/guardians of adolescents (N = 192) who agreed to be circumcised or were recently circumcised in South Africa, Tanzania, and Zimbabwe...
April 3, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29615375/all-patients-should-be-screened-for-diabetes-before-total-joint-arthroplasty
#9
Noam Shohat, Karan Goswami, Majd Tarabichi, Emily Sterbis, Timothy L Tan, Javad Parvizi
BACKGROUND: Diabetes is highly prevalent in patients with osteoarthritis before total joint arthroplasty and presents a higher risk of adverse postoperative outcomes. However, the rate of diabetes in this population and optimal screening strategies remain unknown. METHODS: We prospectively screened patients undergoing elective total joint arthroplasty for diabetes using glycated hemoglobin (HbA1c) and fasting blood glucose (FBG) levels. Screening was conducted within 2 time periods between 2012 and 2017...
February 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29613947/nationwide-trends-in-mortality-following-penetrating-trauma-are-we-up-for-the-challenge
#10
Joseph V Sakran, Ambar Mehta, Ryan Fransman, Avery B Nathens, Bellal Joseph, Alistair Kent, Elliott R Haut, David T Efron
OBJECTIVES: Despite a focus on improved pre-hospital care, penetrating injuries contribute substantially to trauma mortality in the United States (U.S.). We therefore analyzed contemporary trends in pre-hospital mortality from penetrating trauma in the past decade. METHODS: We identified patients in the The National Trauma Data Bank from 2007-2010 ('early period') and 2011-2014 ('late period') with gunshot (GSW) and stab wounds (SW), who were treated at hospitals that recorded dead-on-arrival statistics...
April 3, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29611155/managing-the-diabetic-foot-ulcer-how-best-practices-fit-the-real-2018-united-states
#11
Nicole Ilonzo, Munir Patel, John C Lantis
Diabetes Mellitus is a serious systemic illness that has an epidemic-like increasing prevalence in the United States, as well as the rest of the world. With the increasing number of people with diabetes comes the higher incidence of diabetes-related complications. One of these known complications, diabetic foot ulcers (DFU), has an estimated lifetime incidence of 15% in diabetics. Having a DFU increases the risk of infection, amputation, and even death, which is why prompt treatment and surveillance of such ulcers is imperative...
March 29, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29577556/the-effect-of-increasing-body-mass-index-on-laparoscopic-surgery-for-colon-and-rectal-cancer
#12
Stephen Bell, Joseph C Kong, Roger Wale, Margaret Staples, Karen Oliva, Simon Wilkins, Paul Mc Murrick, Satish K Warrier
BACKGROUND: Obesity is common in Western countries and its prevalence is increasing. Colorectal cancer is common, and surgery for colorectal cancer is technically more challenging in obese patients. Laparoscopic surgery for colon cancer has been shown to be oncologically equivalent, with improved short- term outcomes. Laparoscopic surgery for rectal cancer has proven technically challenging, and recent results have raised concerns about oncologic equivalence. OBJECTIVE: To evaluate the effect of body mass index (BMI) on the clinical and oncological outcomes of surgery for colorectal cancer, including the rate at which laparoscopic surgery is attempted and the rate at which laparoscopic surgery is converted to open surgery...
March 25, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29572395/opportunities-for-better-value-wound-care-a-multiservice-cross-sectional-survey-of-complex-wounds-and-their-care-in-a-uk-community-population
#13
Trish A Gray, Sarah Rhodes, Ross A Atkinson, Katy Rothwell, Paul Wilson, Jo C Dumville, Nicky A Cullum
BACKGROUND: Complex wounds impose a substantial health economic burden worldwide. As wound care is managed across multiple settings by a range of healthcare professionals with varying levels of expertise, the actual care delivered can vary considerably and result in the underuse of evidence-based interventions, the overuse of interventions supported by limited evidence and low value healthcare. OBJECTIVES: To quantify the number, type and management of complex wounds being treated over a two-week period and to explore variations in care by comparing current practices in wound assessment, prevention and treatment...
March 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29571291/factors-associated-to-prevalence-and-treatment-of-carbapenem-resistant-enterobacteriaceae-infections-a-seven-years-retrospective-study-in-three-tertiary-care-hospitals
#14
Feng Pang, Xiu-Qin Jia, Qi-Gang Zhao, Yi Zhang
BACKGROUND: The increasing incidence of carbapenem-resistant Enterobacteriaceae (CRE), has resulted in a difficult problem in the current clinical anti-infective treatment. We performed a retrospective analysis of prevalence and treatment for CRE infections patients. METHODS: This study was conducted in three tertiary care hospitals from January 1, 2010 to December 30, 2016. Baseline data, treatment, and outcomes were collected in patients with ventilator-associated bacterial pneumonia (VABP), bacteremia, complicated urinary tract infection (cUTI)/acute pyelonephritis (AP), hospital-acquired bacterial pneumonia (HABP), superficial wound infection (SWI), biliary tract infection (BTI), deep wound infection (DWI) and sterile body fluids infection (SBFI) due to CRE...
March 23, 2018: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29570542/caring-for-the-orthopaedic-patient-with-a-history-of-bariatric-surgery
#15
Allyson S Chicoski
Bariatric surgery is performed on the gastrointestinal tract as a solution to obesity, and prevalence of these surgical procedures continues to rise. Bariatric surgery creates restrictive and/or malabsorptive properties, causing nutritional deficits from the physiological changes in absorption and a hypoacidic environment. Although surgery induces sustained weight loss, decreases mortality, and provides resolution or improvement to comorbidities of obesity, it can also come with complications. Common long-term complications of bariatric surgery include malnutrition, anemia, impaired wound healing, and impaired bone health...
March 2018: Orthopaedic Nursing
https://www.readbyqxmd.com/read/29564946/virulence-factor-genes-in-staphylococcus-aureus-isolated-from-diabetic-foot-soft-tissue-and-bone-infections
#16
Gerardo Víquez-Molina, Javier Aragón-Sánchez, Cristian Pérez-Corrales, Christian Murillo-Vargas, María Eugenia López-Valverde, Benjamin A Lipsky
The aim of this study is to describe the presence of genes encoding for 4 virulence factors (pvl, eta, etb, and tsst), as well as the mecA gene conferring resistance to beta-lactam antibiotics, in patients with diabetes and a staphylococcal foot infection. We have also analyzed whether isolates of Staphylococcus aureus from bone infections have a different profile for these genes compared with those from exclusively soft tissue infections. In this cross-sectional study of a prospectively recruited series of patients admitted to the Diabetic Foot Unit, San Juan de Dios Hospital, San José, Costa Rica with a moderate or severe diabetic foot infection (DFI), we collected samples from infected soft tissue and from bone during debridement...
March 1, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/29563015/post-burn-pruritus-in-pediatric-burn-patients
#17
Sophie Maria Pierrette Nieuwendijk, Iris Johanne de Korte, Mereille Marren Pursad, Monique van Dijk, Heinz Rode
BACKGROUND: Pruritus is a common problem seen in the healing process of a burn wound and gives great discomfort for the patient. Most research in this field has been done in the adult population, so evidence in the pediatric population is still lacking PURPOSE: The aims of this study were to assess the incidence and severity of post-burn pruritus, identify predictors for pruritus and evaluate the pharmacological treatments in a pediatric setting. METHODS: Pruritus was assessed in this prospective observational study using a numeric rating scale and the Itch Man Scale applied by the patients' caregiver...
March 18, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29561340/validation-of-the-healthy-foot-screen-a-novel-assessment-tool-for-common-clinical-abnormalities
#18
Reneeka Persaud, Patricia M Coutts, Alisa Brandon, Luvneet Verma, James A Elliott, R Gary Sibbald
GENERAL PURPOSE: The purpose of this learning activity is to provide information about the Healthy Foot Screen, a new tool for assessment of common foot abnormalities. TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After completing this continuing education activity, you should be able to:1...
April 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29559159/risk-factor-meta-analysis-and-bayesian-estimation-of-genetic-parameters-and-breeding-values-for-hypersensibility-to-cutaneous-habronematidosis-in-donkeys
#19
Francisco Javier Navas González, Jordi Jordana Vidal, María Esperanza Camacho Vallejo, Jose Manuel León Jurado, Manuel Rafael de la Haba Giraldo, Cecilio Barba Capote, Juan Vicente Delgado Bermejo
Cutaneous habronematidosis (CH) is a highly prevalent seasonally recurrent skin disease that affects donkeys as a result from the action of spirurid stomach worm larvae. Carrier flies mistakenly deposit these larvae on previous skin lesions or on the moisture of natural orifices, causing distress and inflicting relapsing wounds to the animals. First, we carried out a meta-analysis of the predisposing factors that could condition the development of CH in Andalusian donkeys. Second, basing on the empirical existence of an inter and intrafamilial variation previously addressed by owners, we isolated the genetic background behind the hypersensibility to this parasitological disease...
March 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29550312/fdg-pet-ct-for-early-detection-and-localization-of-left-ventricular-assist-device-infection-impact-on-patient-management-and-outcome
#20
Jongho Kim, Erika D Feller, Wengen Chen, Yuanyuan Liang, Vasken Dilsizian
OBJECTIVES: The feasibility of18 F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) for the diagnosis of left ventricular assist device (LVAD) infection has been demonstrated. Beyond the diagnoses of LVAD infection, the authors hypothesized that the pattern and site of the infection along its various components may significantly impact clinical management and patient outcome. BACKGROUND: In patients with end-stage heart failure, the clinical use of LVAD for destination therapy is on the rise, accompanied by a higher prevalence of infections and serious complications...
March 9, 2018: JACC. Cardiovascular Imaging
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