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https://www.readbyqxmd.com/read/28547702/emerging-treatments-in-eating-disorders
#1
REVIEW
Michael Lutter
Eating disorders (EDs), including anorexia nervosa, bulimia nervosa, and binge-eating disorder, constitute a class of common and deadly psychiatric disorders. While numerous studies in humans highlight the important role of neurobiological alterations in the development of ED-related behaviors, the precise neural substrate that mediates this risk is unknown. Historically, pharmacological interventions have played a limited role in the treatment of eating disorders, typically providing symptomatic relief of comorbid psychiatric issues, like depression and anxiety, in support of the standard nutritional and psychological treatments...
May 25, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28544668/intolerance-of-uncertainty-in-eating-disorders-a-systematic-review-and-meta-analysis
#2
REVIEW
Melanie Brown, Lauren Robinson, Giovanna Cristina Campione, Kelsey Wuensch, Tom Hildebrandt, Nadia Micali
Intolerance of uncertainty is an empirically supported transdiagnostic construct that may have relevance in understanding eating disorders. We conducted a meta-analysis and systematic review of intolerance of uncertainty in eating disorders using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We calculated random-effects standardised mean differences (SMD) for studies utilising the Intolerance of Uncertainty Scale (IUS) and summarised additional studies descriptively...
May 23, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28542783/risk-of-eating-disorders-in-immigrant-populations
#3
L Mustelin, A M Hedman, L M Thornton, R Kuja-Halkola, A Keski-Rahkonen, E Cantor-Graae, C Almqvist, A Birgegård, P Lichtenstein, P B Mortensen, C B Pedersen, C M Bulik
OBJECTIVE: The risk of certain psychiatric disorders is elevated among immigrants. To date, no population studies on immigrant health have addressed eating disorders. We examined whether risk of eating disorders in first- and second-generation immigrants differs from native-born Danes and Swedes. METHOD: All individuals born 1984-2002 (Danish cohort) and 1989-1999 (Swedish cohort) and residing in the respective country on their 10th birthday were included. They were followed up for the development of eating disorders based on out-patient and in-patient data...
May 19, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28534123/attention-deficit-hyperactivity-disorder-symptoms-and-psychological-comorbidity-in-eating-disorder-patients
#4
L Sala, G Martinotti, M L Carenti, L Romo, M Oumaya, A Pham-Scottez, F Rouillon, P Gorwood, L Janiri
PURPOSE: There is some evidence that eating disorders (ED) and Attention-deficit/hyperactivity disorder (ADHD) share common clinical features and that ADHD might contribute to the severity of eating disorders. A greater understanding of how the presence of comorbid ADHD may affect the psychopathological framework of eating disorder seems of primary importance. The aim of our study was to evaluate rates of ADHD in three ED subgroups of inpatients: anorexia nervosa restricting type (AN-R), anorexia nervosa binge-eating/purging type (AN-BP) and bulimia nervosa (BN)...
May 22, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28532967/avoidant-restrictive-food-intake-disorder-arfid
#5
Jacqueline Zimmerman, Martin Fisher
Avoidant/restrictive food intake disorder (ARFID) is an entirely new diagnosis in the DSM-5. ARFID replaces "feeding disorder of infancy or early childhood," which was a diagnosis in the DSM-IV restricted to children 6 years of age or younger; ARFID has no such age limitations and it is distinct from anorexia nervosa and bulimia nervosa in that there is no body image disturbance. ARFID involves a complex and heterogenous etiology, which is reviewed herein. What is known to date regarding the characteristics and medical and psychiatric comorbidities of this patient population are described and compared to other eating disorders...
April 2017: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/28532966/bulimia-nervosa-purging-disorder
#6
Marigold Castillo, Eric Weiselberg
Bulimia nervosa was first described in 1979 by British psychiatrist Gerald Russell as a "chronic phase of anorexia nervosa" in which patients overeat and then use compensatory mechanisms, such as self-induced vomiting, laxatives, or prolonged periods of starvation. The characterization of bulimia nervosa continues to evolve with the introduction of the DSM-5 in 2013. In this article, the epidemiology and risk factors of bulimia nervosa are identified and reviewed, along with the medical complications and psychiatric comorbidities...
April 2017: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/28523542/eating-disorders-and-epigenetics
#7
Lea Thaler, Howard Steiger
Eating disorders (EDs) are characterized by intense preoccupation with shape and weight and maladaptive eating practices. The complex of symptoms that characterize EDs often arise through the activation of latent genetic potentials by environmental exposures, and epigenetic mechanisms are believed to link environmental exposures to gene expression. This chapter provides an overview of genetic factors acting in the etiology of EDs. It then provides a background to the hypothesis that epigenetic mechanisms link stresses such as obstetric complications and childhood abuse as well as effects of malnutrition to eating disorders (EDs)...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28520584/eating-disorders-and-bone-metabolism-in-women
#8
Lauren Robinson, Nadia Micali, Madhusmita Misra
PURPOSE OF REVIEW: Eating Disorders are psychiatric disorders associated with a high risk for low bone mineral density (BMD) and fractures. Low BMD is a consequence of undernutrition, changes in body composition, and hormonal alterations. This review summarizes recent findings regarding novel strategies for assessing bone outcomes in patients with eating disorders, factors contributing to altered bone metabolism, and possible therapeutic strategies. RECENT FINDINGS: Emerging research in this field suggests that not only anorexia nervosa, but also bulimia nervosa results in lower BMD compared to controls...
May 16, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28510006/evaluation-of-the-dsm-5-severity-specifier-for-bulimia-nervosa-in-treatment-seeking-youth
#9
Antonios Dakanalis, Fabrizia Colmegna, Maria Assunta Zanetti, Ester Di Giacomo, Giuseppe Riva, Massimo Clerici
A new severity specifier for bulimia nervosa (BN), based on the frequency of inappropriate weight compensatory behaviours (e.g., laxative misuse, self-induced vomiting, fasting, diuretic misuse, and excessive exercise), has been added to the most recent (fifth) edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as a means of addressing variability and heterogeneity in the severity of the disorder. While existing research provides support for the DSM-5 severity specifier for BN in adult patients, evidence for its validity and clinical utility in youth is currently lacking...
May 16, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28503699/eating-psychopathology-and-psychosocial-impairment-in-patients-treated-at-a-singapore-eating-disorders-treatment-programme
#10
Kah Wee Ng, Angeline Kuek, Huei Yen Lee
INTRODUCTION: There is limited data on the psychopathology of eating disorders in Singapore. This study: (a) describes levels of eating psychopathology and psychosocial impairment among individuals diagnosed with eating disorders at our hospital; and (b) compares the related psychopathology of these patients. METHODS: Between 1 August 2010 and 31 July 2012, 257 individuals who met the diagnostic criteria for eating disorders completed the Eating Disorder Examination Questionnaire (EDE-Q) and Clinical Impairment Assessment questionnaire (CIA)...
May 15, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28502528/neural-response-to-catecholamine-depletion-in-remitted-bulimia-nervosa-relation-to-depression-and-relapse
#11
Stefanie Verena Mueller, Yoan Mihov, Andrea Federspiel, Roland Wiest, Gregor Hasler
Bulimia nervosa has been associated with a dysregulated catecholamine system. Nevertheless, the influence of this dysregulation on bulimic symptoms, on neural activity, and on the course of the illness is not clear yet. An instructive paradigm for directly investigating the relationship between catecholaminergic functioning and bulimia nervosa has involved the behavioral and neural responses to experimental catecholamine depletion. The purpose of this study was to examine the neural substrate of catecholaminergic dysfunction in bulimia nervosa and its relationship to relapse...
May 11, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28500866/presence-of-eating-disorders-and-its-relationship-to-anxiety-and-depression-in-pregnant-women
#12
Amanda Maihara Dos Santos, Gláucia Rosana Guerra Benute, Niraldo Oliveira Dos Santos, Roseli Mieko Yamamoto Nomura, Mara Cristina Souza de Lucia, Rossana Pulcineli Vieira Francisco
BACKGROUND: women who have inadequate nutrient intake are more likely to develop a risky pregnancy. The purpose of this study was to determine the presence of eating disorders and its association with anxiety and depression symptomatology in high-risk pregnancies. METHODS: this is a cross-sectional and prospective study conducted at the tertiary university hospital in the city of São Paulo, Brazil. 913 pregnant women waiting for the Obstetrics' outpatient appointment were invited to participate in the study on their 2nd and 3rd trimester of pregnancy...
May 8, 2017: Midwifery
https://www.readbyqxmd.com/read/28500621/symptoms-predicting-psychosocial-impairment-in-bulimia-nervosa
#13
Paul E Jenkins, Jessica Staniford, Amy Luck
PURPOSE: The current study aimed to determine which particular eating disorder (ED) symptoms and related features, such as BMI and psychological distress, uniquely predict impairment in bulimia nervosa (BN). METHODS: Two hundred and twenty-two adults with BN completed questionnaires assessing ED symptoms, general psychological distress, and psychosocial impairment. Regression analyses were used to determine predictors which account for variance in impairment. RESULTS: Four variables emerged as significant predictors of psychosocial impairment: concerns with eating; concerns with weight and shape; dietary restraint; and general psychological distress...
May 12, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28494809/the-ped-t-trial-protocol-the-effect-of-physical-exercise-and-dietary-therapy-compared-with-cognitive-behavior-therapy-in-treatment-of-bulimia-nervosa-and-binge-eating-disorder
#14
Therese Fostervold Mathisen, Jan H Rosenvinge, Gunn Pettersen, Oddgeir Friborg, KariAnne Vrabel, Solfrid Bratland-Sanda, Mette Svendsen, Trine Stensrud, Maria Bakland, Rolf Wynn, Jorunn Sundgot-Borgen
BACKGROUND: Sufferers from bulimia nervosa (BN) and binge eating disorder (BED) underestimate the severity risk of their illness and, therefore, postpone seeking professional help for years. Moreover, less than one in five actually seek professional help and only 50% respond to current treatments, such as cognitive behavioral therapy (CBT). The impetus for the present trial is to explore a novel combination treatment approach adapted from physical exercise- and dietary therapy (PED-t)...
May 12, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28493727/military-sexual-trauma-is-associated-with-eating-disorders-while-combat-exposure-is-not
#15
Jessica Y Breland, Rosemary Donalson, Yongmei Li, Claire L Hebenstreit, Lizabeth A Goldstein, Shira Maguen
OBJECTIVE: There are strong associations among trauma and eating disorders. However, while trauma and eating disorders are more common among veterans than other populations, there is little information on how military-specific stressors affect eating disorder risk. This study's objective was to determine whether military sexual trauma and combat exposure were independent predictors of eating disorders among women veterans, a high-risk group. METHOD: Participants were women age 18-70, using VA medical center services, without psychotic disorders or suicidal ideation (N = 407)...
May 11, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28489323/mild-moderate-meaningful-examining-the-psychological-and-functioning-correlates-of-dsm-5-eating-disorder-severity-specifiers
#16
Loren Gianini, Christina A Roberto, Evelyn Attia, B Timothy Walsh, Jennifer J Thomas, Kamryn T Eddy, Carlos M Grilo, Thomas Weigel, Robyn Sysko
OBJECTIVE: This study evaluated the DSM-5 severity specifiers for treatment-seeking groups of participants with anorexia nervosa (AN), the purging form of bulimia nervosa (BN), and binge eating disorder (BED). METHOD: Hundred and sixty-two participants with AN, 93 participants with BN, and 343 participants with BED were diagnosed using semi-structured interviews, sub-categorized using DSM-5 severity specifiers and compared on demographic and cross-sectional clinical measures...
May 10, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28482293/temporal-associations-between-affective-instability-and-dysregulated-eating-behavior-in-bulimia-nervosa
#17
Laura A Berner, Ross D Crosby, Li Cao, Scott G Engel, Jason M Lavender, James E Mitchell, Stephen A Wonderlich
Prior research suggests that the construct of emotional instability may be salient to bulimia nervosa (BN), but no study to date has used ecological momentary assessment (EMA) to examine its temporal association with binge eating and purging. In the current study, 133 women with DSM-IV BN used portable digital devices to provide multiple daily negative affect (NA) and positive affect (PA) ratings and record eating disorder behaviors over 2 weeks. Two state-of-the art indices quantified affective instability: probability of acute change (PAC), which represents the likelihood of extreme affective increases, and mean squared successive difference (MSSD), which represents average change over successive recordings...
April 26, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28474473/short-term-treatment-outcomes-and-dropout-risk-in-men-and-women-with-eating-disorders
#18
Zaida Agüera, Isabel Sánchez, Roser Granero, Nadine Riesco, Trevor Steward, Virginia Martín-Romera, Susana Jiménez-Murcia, Xandra Romero, Mariarita Caroleo, Cristina Segura-García, José Manuel Menchon, Fernando Fernández-Aranda
This study compared treatment outcomes between men and women with eating disorders (EDs) and analysed clinical predictors of treatment outcome. Our sample consisted of 131 male and 131 female ED patients who underwent cognitive behavioural therapy treatment. ED severity, personality and psychopathology were assessed using standard instruments. We found that the risk of dropout was higher for men with bulimia nervosa (BN) than for women with BN and that men with BN and other specified feeding and EDs were more likely to obtain full remission in comparison with their female counterparts...
May 4, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28467893/meta-analysis-of-the-effects-of-intranasal-oxytocin-on-interpretation-and-expression-of-emotions
#19
REVIEW
Jenni Leppanen, Kah Wee Ng, Kate Tchanturia, Janet Treasure
Accurate interpretation and appropriate expression of emotions are key aspects of social-cognition. Several mental disorders are characterised by transdiagnostic difficulties in these areas and, recently, there has been increasing interest in exploring the effects of oxytocin on social-emotional functioning. This review consists of 33 studies. Fifteen of the studies included people with autism spectrum disorder, schizophrenia, borderline personality disorder, frontotemporal dementia, anorexia nervosa, bulimia nervosa, post-traumatic stress disorder, depression, and opioid and alcohol dependence...
April 30, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28467270/educator-preparedness-for-mental-health-in-adolescents-opportunities-for-school-nurse-leadership
#20
Tiffany Smith-Fromm, Robin A Evans-Agnew
One in five adolescents will experience a mental health event in their lifetime. If left untreated, depression, anxiety, attention-deficit/hyperactivity, and anorexia/bulimia can elevate the risk of dropping out of high school. As a key principle of 21st-century nursing practice, school nurses must provide leadership in educating school staff in identifying and responding to mental health issues in high school settings. This article describes the results of an online survey assessing secondary educators' knowledge of and experience with mental health issues in one school district...
May 1, 2017: NASN School Nurse
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