keyword
MENU ▼
Read by QxMD icon Read
search

hiv prophylaxis preexposure

keyword
https://www.readbyqxmd.com/read/29048955/integrating-hiv-preexposure-prophylaxis-prep-into-routine-preventive-health-care-to-avoid-exacerbating-disparities
#1
Sarah K Calabrese, Douglas S Krakower, Kenneth H Mayer
More than 3 decades since its emergence in the United States, HIV continues to spread and disproportionately affect socially marginalized groups. Preexposure prophylaxis (PrEP), a highly effective prevention strategy federally approved since 2012, could fundamentally alter the course of the epidemic. However, PrEP's potential has not been fully realized, in part because health care providers have been slow to adopt PrEP in clinical practice and have been selective in their discussion of PrEP with patients. This nonstandardized approach has constrained PrEP access...
October 19, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29020235/redefining-hiv-preexposure-prophylaxis-failures
#2
Julia L Marcus, Leo B Hurley, Dong Phuong Nguyen, Michael J Silverberg, Jonathan E Volk
No abstract text is available yet for this article.
July 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29020194/comparison-of-measures-of-adherence-to-hiv-preexposure-prophylaxis-among-adolescent-and-young-men-who-have-sex-with-men-in-the-united-states
#3
Catherine A Koss, Sybil G Hosek, Peter Bacchetti, Peter L Anderson, Albert Y Liu, Howard Horng, Leslie Z Benet, Karen Kuncze, Alexander Louie, Parya Saberi, Craig M Wilson, Monica Gandhi
Background: Young men who have sex with men (MSM) are disproportionately impacted by HIV. Preexposure prophylaxis (PrEP) could reduce HIV acquisition among youth, but sub-optimal adherence threatens effectiveness. Optimal metrics of PrEP adherence among adolescents have not been defined. Methods: The ATN 110 and 113 studies provided daily oral PrEP with tenofovir (TFV) disoproxil fumarate/emtricitabine over 48 weeks to a diverse population of MSM (15-22 years). Self-reported adherence was assessed and PrEP drug concentrations measured from hair and dried blood spot (DBS) samples; 23% of participants received Wisepill electronic monitoring devices...
August 24, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28991887/changes-in-kidney-function-associated-with-daily-tenofovir-disoproxil-fumarate-emtricitabine-for-hiv-preexposure-prophylaxis-use-in-the-united-states-demonstration-project
#4
Eric C Tang, Eric Vittinghoff, Peter L Anderson, Stephanie E Cohen, Susanne Doblecki-Lewis, Oliver Bacon, Megan E Coleman, Wairimu Chege, Susan P Buchbinder, Michael A Kolber, Richard Elion, Michael Shlipak, Albert Y Liu
BACKGROUND: HIV preexposure prophylaxis (PrEP) using daily oral tenofovir-disoproxil-fumarate/emtricitabine (TDF/FTC) is effective for preventing HIV acquisition, but concerns remain about its potential kidney toxicity. This study examined kidney function in individuals using PrEP in real-world clinical settings. SETTING: Demonstration project in two sexually transmitted infection clinics and a community health center. METHODS: We evaluated kidney function among men who have sex with men and transgender women taking TDF/FTC PrEP for up to 48 weeks...
October 4, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28902677/disparities-in-awareness-of-hiv-postexposure-and-preexposure-prophylaxis-among-notified-partners-of-hiv-positive-individuals-new-york-city-2015-2017
#5
Kavita Misra, Chi-Chi Udeagu
BACKGROUND: Named sex- or needle-sharing partners of HIV-positive individuals are a priority prevention population due to their known HIV exposure. Understanding postexposure and preexposure prophylaxis (PEP and PrEP) awareness and use among them is important for successful interventions. METHODS: Data from notified partners of HIV-positive individuals (New York City, May 2015-April 2017) were analyzed to describe PEP/PrEP awareness, provider discussion, and use by sociodemographic and risk characteristics...
October 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28902562/preexposure-prophylaxis-adapting-hiv-prevention-models-to-achieve-worldwide-access
#6
Stewart Landers, Farzana Kapadia
No abstract text is available yet for this article.
October 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28876325/modernizing-field-services-for-human-immunodeficiency-virus-and-sexually-transmitted-infections-in-the-united-states
#7
Matthew R Golden, David A Katz, Julia C Dombrowski
Public health field services for sexually transmitted infections (STIs) have not adequately evolved to address the expanding scale of the STI problem, its concentration among men who have sex with men, the emergence of new communication technologies and the availability of antiretroviral therapy as a cornerstone of human immunodeficiency virus (HIV) prevention. Field services need to modernize. Modernization should seek to expand field services objectives beyond sex partner STI testing and treatment to include: HIV testing of persons with bacterial STI and their partners, including efforts to promote frequent HIV/STI testing; increased condom access; linkage and relinkage to HIV care and promotion of viral suppression; preexposure prophylaxis promotion; linkage to long-acting contraception; and referral for health insurance...
October 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28876282/outcomes-of-preexposure-prophylaxis-referrals-from-public-sti-clinics-and-implications-for-the-preexposure-prophylaxis-continuum
#8
Ramona Bhatia, Laxmi Modali, Matthew Lowther, Nancy Glick, Margo Bell, Sarah Rowan, Kristin Keglovitz, John Schneider
BACKGROUND: Human immunodeficiency virus preexposure prophylaxis (PrEP) uptake remains low in high-risk populations. Sexually transmitted infection (STI) clinics reach PrEP-eligible persons and may be ideal settings to model PrEP implementation. METHODS: Consenting PrEP-eligible patients identified at Chicago Department of Public Health STI Clinics were actively referred to PrEP partner sites between June 1, 2015, and May 31, 2016. Outcomes included successful contact by a partner site, linkage to a partner site, and receipt of a PrEP prescription...
August 30, 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28873128/safety-and-feasibility-of-antiretroviral-preexposure-prophylaxis-for-adolescent-men-who-have-sex-with-men-aged-15-to-17-years-in-the-united-states
#9
Sybil G Hosek, Raphael J Landovitz, Bill Kapogiannis, George K Siberry, Bret Rudy, Brandy Rutledge, Nancy Liu, D Robert Harris, Kathleen Mulligan, Gregory Zimet, Kenneth H Mayer, Peter Anderson, Jennifer J Kiser, Michelle Lally, Jennifer Brothers, Kelly Bojan, Jim Rooney, Craig M Wilson
Importance: Adolescents represent a key population for implementing preexposure prophylaxis (PrEP) interventions worldwide, yet tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for PrEP is only licensed for adults. Objective: To examine the safety of and adherence to PrEP along with changes in sexual risk behavior among adolescent men who have sex with men (MSM). Design, Setting, and Participants: Adolescent Medicine Trials Network for HIV/AIDS Interventions 113 (Project PrEPare) was a PrEP demonstration project that evaluated the safety, tolerability, and acceptability of TDF/FTC and patterns of use, rates of adherence, and patterns of sexual risk behavior among healthy young MSM aged 15 to 17 years...
September 5, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28873123/human-immunodeficiency-virus-preexposure-prophylaxis-for-adolescent-men-how-do-we-ensure-health-equity-for-at-risk-young-men
#10
Renata Arrington-Sanders
No abstract text is available yet for this article.
September 5, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28853676/hiv-aids-conspiracy-beliefs-and-intention-to-adopt-preexposure-prophylaxis-among-black-men-who-have-sex-with-men-in-los-angeles
#11
Ronald A Brooks, Vincent C Allen, Rotrease Regan, Matt G Mutchler, Ramon Cervantes-Tadeo, Sung-Jae Lee
In the United States, black men who have sex with men (MSM) are the group most affected by the HIV/AIDS epidemic. Pre-exposure prophylaxis (PrEP) is an important new HIV prevention strategy that may help reduce new HIV infections among black MSM. This analysis examined the association between HIV/AIDS conspiracy beliefs and intentions to adopt PrEP among 224 black MSM. The likelihood of adopting PrEP was assessed and more than half (60%) of the study population indicated a high intention to adopt PrEP. HIV/AIDS genocidal and treatment-related conspiracies were assessed using scales previously validated with black MSM...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28834798/estimated-coverage-to-address-financial-barriers-to-hiv-preexposure-prophylaxis-among-persons-with-indications-for-its-use-united-states-2015
#12
Dawn K Smith, Michelle Van Handel, Rebecca Huggins
BACKGROUND: An estimated 1.2 million American adults engage in sexual and drug use behaviors that place them at significant risk of acquiring HIV infection. Engagement in health care for the provision of daily oral antiretroviral medication as preexposure prophylaxis (PrEP), when clinically indicated, could substantially reduce the number of new HIV infections in these persons. However, resources to cover the financial cost of PrEP care is an anticipated barrier for many of the populations with high numbers of new HIV infections...
August 22, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28828489/safety-and-tolerability-of-maraviroc-containing-regimens-to-prevent-hiv-infection-in-women-a-phase-2-randomized-trial
#13
RANDOMIZED CONTROLLED TRIAL
Roy M Gulick, Timothy J Wilkin, Ying Q Chen, Raphael J Landovitz, K Rivet Amico, Alicia M Young, Paul Richardson, Mark A Marzinke, Craig W Hendrix, Susan H Eshleman, Ian McGowan, Leslie M Cottle, Adriana Andrade, Cheryl Marcus, Karin L Klingman, Wairimu Chege, Alex R Rinehart, James F Rooney, Philip Andrew, Robert A Salata, Marc Siegel, Yukari C Manabe, Ian Frank, Ken Ho, Jorge Santana, Joanne D Stekler, Shobha Swaminathan, Marybeth McCauley, Sally Hodder, Kenneth H Mayer
Background: Maraviroc (MVC) is a candidate drug for HIV preexposure prophylaxis (PrEP). Objective: To assess the safety and tolerability of MVC-containing PrEP over 48 weeks in U.S. women at risk for HIV infection. Design: Phase 2 randomized, controlled, double-blinded study of 4 antiretroviral regimens used as PrEP. (ClinicalTrials.gov: NCT01505114). Setting: 12 clinical research sites of the HIV Prevention Trials Network and AIDS Clinical Trials Group...
September 19, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28817332/individual-versus-community-level-risk-compensation-following-preexposure-prophylaxis-of-hiv
#14
Martin Holt, Dean A Murphy
We analyzed the concept of risk compensation and how it has been applied in HIV prevention, paying particular attention to the strategy of HIV preexposure prophylaxis (PrEP). In risk compensation, reduced perceptions of risk after the introduction of a preventative intervention lead to more frequent risk-taking behavior. Such a change may undermine the intervention's protective benefits. We found that many studies purporting to investigate risk compensation do not assess or report changes in perceptions of risk, instead relying on behavioral measures...
October 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28817325/hiv-preexposure-prophylaxis-and-condomless-sex-disentangling-personal-values-from-public-health-priorities
#15
Sarah K Calabrese, Kristen Underhill, Kenneth H Mayer
Daily HIV preexposure prophylaxis (PrEP) is an effective form of HIV protection that remains unknown and inaccessible for many people in the United States despite receiving federal approval over five years ago. PrEP is supported by the public health community, but forgoing condoms while taking PrEP has proven controversial; this controversy may be contributing to the lag in PrEP uptake. We argue that limiting PrEP access based on anticipated or actual sexual behavior contradicts the goals of public health research and practice and is not scientifically justified...
October 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28714706/hiv-risk-and-multiple-sources-of-heterosexism-among-young-black-men-who-have-sex-with-men
#16
Wilson Vincent, Lance M Pollack, David M Huebner, John L Peterson, Wayne T Steward, Gregory M Rebchook, Erik D Storholm, Susan M Kegeles
OBJECTIVE: This study examined whether the association between social support and condom self-efficacy would be moderated by (a) internalized heterosexism among and (b) enacted heterosexism experienced by young Black men who have sex with men (YBMSM), who contend with high HIV incidence, heterosexism, and low uptake of preexposure prophylaxis. METHOD: Participants were 1,210 YBMSM (ages 18-29) who completed measures of social support, internalized and enacted heterosexism, and condom self-efficacy in 2 large cities in the southern United States as part of a community-level HIV-prevention study...
July 17, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28700394/medication-adherence-condom-use-and-sexually-transmitted-infections-in-australian-preexposure-prophylaxis-users
#17
Luxi Lal, Jennifer Audsley, Dean A Murphy, Christopher K Fairley, Mark Stoove, Norm Roth, Richard Moore, Ban K Tee, Nalagafiar Puratmaja, Peter L Anderson, David Leslie, Robert M Grant, John De Wit, Edwina Wright
OBJECTIVE: HIV preexposure prophylaxis (PrEP) decreases risk of HIV acquisition; however, its efficacy is closely dependent on adherence. There is also concern that the preventive effect of PrEP may be offset by risk compensation, notably an increase in condomless anal sex. DESIGN: Multisite, open-label demonstration study that recruited people at current or recent risk of HIV infection in Melbourne, Australia. METHODS: Participants were recruited from three general practice clinics and one sexual health clinic in Melbourne and consented to take daily tenofovir/emtricitabine (TFV/FTC) for 30 months...
July 31, 2017: AIDS
https://www.readbyqxmd.com/read/28682799/online-to-offline-models-in-hiv-service-delivery
#18
Tarandeep Anand, Chattiya Nitpolprasert, Nittaya Phanuphak
PURPOSE OF REVIEW: Half the world's population has access to Internet and technologies, and utilization is near-ubiquitous among providers and key populations. Despite being so well connected; identifying, reaching and linking vulnerable populations to HIV clinical services remains a global challenge. This review highlights the emerging online-to-offline (O2O) models, their potential in scaling up services, and evaluating impact, and implications for future research. RECENT FINDINGS: Globally, four major types of O2O models have been implemented, primarily in the West and Asia, especially among MSM and transgender women...
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28657968/urine-tenofovir-and-emtricitabine-concentrations-provide-biomarker-for-exposure-to-hiv-preexposure-prophylaxis
#19
Richard E Haaland, Amy Martin, Angela Holder, Jeffrey J Fountain, LaShonda Hall, Nicole A Pescatore, Sheila Heeke, Colleen F Kelley
No abstract text is available yet for this article.
July 17, 2017: AIDS
https://www.readbyqxmd.com/read/28657964/msm-starting-preexposure-prophylaxis-are-at-risk-of-hepatitis-c-virus-infection
#20
Elske Hoornenborg, Roel C A Achterbergh, Maarten F Schim van der Loeff, Udi Davidovich, Arjan Hogewoning, Henry J C de Vries, Janke Schinkel, Maria Prins, Thijs J W van de Laar
OBJECTIVES AND DESIGN: Hepatitis C virus (HCV) has been recognized as an emerging sexually transmitted infection (STI) among HIV-positive MSM. However, HIV-negative MSM at high risk for HIV might also be at increased risk for HCV. We studied the HCV prevalence in HIV-negative MSM who start preexposure prophylaxis (PrEP) in Amsterdam. Phylogenetic analysis was used to compare HCV strains obtained from HIV-negative and HIV-positive MSM. METHODS: At enrolment in the Amsterdam PrEP demonstration project, HIV-negative MSM were tested for the presence of HCV antibodies and HCV RNA...
July 17, 2017: AIDS
keyword
keyword
49280
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"