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https://www.readbyqxmd.com/read/28414665/a-case-of-early-neurosyphilis
#1
M Walker, R Wisler, J Simmons, A Johnson
INTRODUCTION: Neurosyphilis is an infection of the central nervous system by Treponema pallidum, which can occur after the initial syphilis infection. Although commonly associated with late stage disease, patients with early neurosyphilis may present with acute syphilitic meningitis, meningovascular syphilis, or uveitis. CASE: A 28 year old man with a past medical history of HIV (CD4 364);, and recent diagnosis of uveitis presented to the Emergency Department with a positive RPR result...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28203074/temperature-and-ph-sensitive-wearable-materials-for-monitoring-foot-ulcers
#2
Pietro Salvo, Nicola Calisi, Bernardo Melai, Valentina Dini, Clara Paoletti, Tommaso Lomonaco, Andrea Pucci, Fabio Di Francesco, Alberto Piaggesi, Marco Romanelli
Foot ulcers account for 15% of comorbidities associated with diabetes. Presently, no device allows the status of foot ulcers to be continuously monitored when patients are not hospitalized. In this study, we describe a temperature and a pH sensor capable of monitoring diabetic foot and venous leg ulcers developed in the frame of the seventh framework program European Union project SWAN-iCare (smart wearable and autonomous negative pressure device for wound monitoring and therapy). Temperature is measured by exploiting the variations in the electrical resistance of a nanocomposite consisting of multiwalled carbon nanotubes and poly(styrene-b-(ethylene-co-butylene)-b-styrene)...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28160941/the-topological-phase-diagram-of-cimetidine-a-case-of-overall-monotropy
#3
R Céolin, I B Rietveld
Cimetidine is a histamine H2-receptor antagonist used against peptic ulcers. It is known to exhibit crystalline polymorphism. Forms A and D melt within 0.35 degrees from each other and the enthalpies of fusion are similar as well. The present paper demonstrates how to construct a pressure-temperature phase diagram with only calorimetric and volumetric data available. The phase diagram provides the stability domains and the phase equilibria for the phases A, D, the liquid and the vapor. Cimetidine is overall monotropic with form D the only stable solid phase...
March 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28096663/pressure-ulcers-in-palliative-ward-patients-hyponatremia-and-low-blood-pressure-as-indicators-of-risk
#4
Danuta Sternal, Krzysztof Wilczyński, Jan Szewieczek
BACKGROUND: Prevention strategies for pressure ulcer formation remain critical in patients with an advanced illness. We analyzed factors associated with the development of pressure ulcers in patients hospitalized in a palliative care ward setting. PATIENTS AND METHODS: This study was a retrospective analysis of 329 consecutive patients with a mean age (± standard deviation) of 70.4±11.8 years (range: 30-96 years, median 70.0 years; 55.3% women), who were admitted to the Palliative Care Department between July 2012 and May 2014...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28012341/walking-cadence-affects-rate-of-plantar-foot-temperature-change-but-not-final-temperature-in-younger-and-older-adults
#5
Prabhav Nadipi Reddy, Glen Cooper, Andrew Weightman, Emma Hodson-Tole, Neil D Reeves
This study examined the relationship between (1) foot temperature in healthy individuals and walking cadence, (2) temperature change at different locations of the foot, and (3) temperature change and its relationship with vertical pressures exerted on the foot. Eighteen healthy adult volunteers (10 between 30 and 40 years - Age: 33.4±2.4years; 8 above 40 years - Age: 54.1±7.7years) were recruited. A custom-made insole with temperature sensors was placed directly onto the plantar surface of the foot and held in position using a sock...
December 6, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27942235/investigating-the-effects-of-strap-tension-during-non-invasive-ventilation-mask-application-a-combined-biomechanical-and-biomarker-approach
#6
Peter R Worsley, George Prudden, George Gower, Dan L Bader
Non-invasive ventilation is commonly used for respiratory support. However, in some cases, mask application can cause pressure ulcers to specific features of the face, resulting in pain and reduced quality of life for the individual. This study investigated the effects of mask strap tension on the biomechanical and biomarker responses at the skin interface. Healthy participants (n = 13) were recruited and assigned two different masks in a random order, which were fitted with three strap conditions representing increments of 5 mm to increase tension...
2016: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/27824259/preliminary-evaluation-of-a-cycling-cleat-designed-for-diabetic-foot-ulcers
#7
Ryan T Crews, Steven R Smith, Ramin Ghazizadeh, Sai Yalla, Stephanie C Wu
BACKGROUND: Offloading devices for diabetic foot ulcers (DFU) generally restrict exercise. In addition to traditional health benefits, exercise could benefit DFU by increasing blood flow and acting as thermotherapy. This study functionally evaluated a cycling cleat designed for forefoot DFU. METHODS: Fifteen individuals at risk of developing a DFU used a recumbent stationary bicycle to complete one 5-minute cycling bout with the DFU cleat on their study foot and one 5-minute bout without it...
November 8, 2016: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/27817985/effects-of-two-different-fabrics-on-skin-barrier-function-under-real-pressure-conditions
#8
M Schario, T Tomova-Simitchieva, A Lichterfeld, H Herfert, G Dobos, N Lahmann, U Blume-Peytavi, J Kottner
BACKGROUND: Pressure Ulcers (PUs) are a severe form of skin and soft tissue lesions, caused by sustained deformation. PU development is complex and depends on different factors. Skin structure and function change during prolonged loading on PU predilection sites and surfaces being in direct contact with skin are likely to have an impact as well. Little is known about the influence of fabrics on skin function under pressure conditions. OBJECTIVES: To investigate skin responses to sustained loading in a sitting position and possible differences between two fabrics...
October 25, 2016: Journal of Tissue Viability
https://www.readbyqxmd.com/read/27794259/an-evaluation-of-fluid-immersion-therapy-for-the-prevention-of-pressure-ulcers
#9
P R Worsley, B Parsons, D L Bader
BACKGROUND: Individuals with impaired mobility can spend prolonged periods on support surfaces, increasing their risk of developing pressure ulcers. Manufacturers have developed mattresses to maximise contact area. The present study evaluated both the biomechanical and physiological responses to lying postures on a Fluid Immersion Simulation mattress. METHODS: Seventeen healthy participants were recruited to evaluate the mattress during three prescribed settings of immersion (high, medium and low)...
October 19, 2016: Clinical Biomechanics
https://www.readbyqxmd.com/read/27768578/a-prospective-observational-study-to-assess-the-use-of-thermography-to-predict-progression-of-discolored-intact-skin-to-necrosis-among-patients-in-skilled-nursing-facilities
#10
Jill Cox, Loretta Kaes, Miguel Martinez, Daniel Moles
Skin temperature may help prospectively determine whether an area of skin discoloration will evolve into necrosis. A prospective, observational study was conducted in 7 skilled nursing facilities to determine if skin temperature measured using infrared thermography could predict the progression of discolored intact skin (blanchable erythema, Stage 1 pressure ulcer, or sus- pected deep tissue injury [sDTI]) to necrosis and to evaluate if nurses could effectively integrate thermography into the clinical setting...
October 2016: Ostomy/wound Management
https://www.readbyqxmd.com/read/27581113/the-healing-effect-of-low-temperature-atmospheric-pressure-plasma-in-pressure-ulcer-a-randomized-controlled-trial
#11
Apirag Chuangsuwanich, Tananchai Assadamongkol, Dheerawan Boonyawan
Pressure ulcers are difficult to treat. Recent reports of low-temperature atmospheric-pressure plasma (LTAPP) indicated its safe and effectiveness in chronic wound care management. It has been shown both in vitro and vivo studies that LTAPP not only helps facilitate wound healing but also has antimicrobial efficacy due to its composition of ion and electron, free radicals, and ultraviolet ray. We studied the beneficial effect of LTAPP specifically on pressure ulcers. In a prospective randomized study, 50 patients with pressure ulcers were divided into 2 groups: Control group received standard wound care and the study group was treated with LTAPP once every week for 8 consecutive weeks in addition to standard wound care...
August 31, 2016: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/27408610/heat-for-wounds-water-filtered-infrared-a-wira-for-wound-healing-a-review
#12
REVIEW
Gerd Hoffmann, Mark Hartel, James B Mercer
BACKGROUND: Water-filtered infrared-A (wIRA) is a special form of heat radiation with high tissue penetration and a low thermal load to the skin surface. wIRA corresponds to the major part of the sun's heat radiation, which reaches the surface of the Earth in moderate climatic zones filtered by water and water vapour of the atmosphere. wIRA promotes healing of acute and chronic wounds both by thermal and thermic as well as by non-thermal and non-thermic cellular effects. METHODS: This publication includes a literature review with search in PubMed/Medline for "water-filtered infrared-A" and "wound"/"ulcus" or "wassergefiltertes Infrarot A" and "Wunde"/"Ulkus", respectively (publications in English and German), and additional analysis of study data...
2016: German Medical Science: GMS E-journal
https://www.readbyqxmd.com/read/27400685/a-penetrating-atherosclerotic-ulcer-rupture-in-the-ascending-aorta-with-hemopericardium-a-case-report
#13
Yuan-Hao Liu, Hung-Yen Ke, Yi-Chang Lin, Chien-Sung Tsai
BACKGROUND: Acute aortic syndrome, including classic aortic dissection, intramural aortic hematoma, and penetrating atherosclerotic ulcer (PAU), is a term used to describe a group of conditions with similar clinical symptoms, but with different pathophysiological mechanisms. PAU is a lesion that penetrates the internal elastic lamina through the media. It is usually located in the descending aorta and rarely observed in the ascending aorta. CASE PRESENTATION: A 76-year-old man with a history of essential hypertension was brought to the emergency department (ED) because of a sudden-onset chest pain at rest...
July 11, 2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27219884/clinical-evaluation-of-human-umbilical-cord-mesenchymal-stem-cell-transplantation-after-angioplasty-for-diabetic-foot
#14
H L Qin, X H Zhu, B Zhang, L Zhou, W Y Wang
Aims: The multilineage differentiation potential of human umbilical cord mesenchymal stem cells (HUCMSCs) holds therapeutic promise for non-healing ulcers and tissue regeneration. The present study evaluated the effects of HUCMSC transplantation after angioplasty for treatment of diabetic foot. Methods: Included in the study were 53 patients (72 limbs) with severe symptoms of Fontaine II-IV diabetic foot accompanied by varying degrees of lower extremity arterial disease. The patients were randomly apportioned to a control group (25 patients; 38 limbs) or an experimental group (28 patients; 34 limbs)...
September 2016: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/27067837/development-of-a-sitting-microenvironment-simulator-for-wheelchair-cushion-assessment
#15
Tyler Freeto, Allissa Cypress, Sarah Amalraj, Mohamed Shaif Yusufishaq, Kath M Bogie
STUDY AIM: Pressure ulcers (PU) are a common comorbidity among wheelchair users. An appropriate wheelchair cushion is essential to relieve pressure and reduce PU development during sitting. The microenvironment, specifically excessive heat and moisture, impacts risk for PU development. An effective wheelchair cushion should maintain a healthy microenvironment at the seating interface. Measurement of heat and moisture can characterize microenvironmental conditions at the wheelchair cushion interface under load...
August 2016: Journal of Tissue Viability
https://www.readbyqxmd.com/read/27065215/using-noncontact-infrared-thermography-for-long-term-monitoring-of-foot-temperatures-in-a-patient-with-diabetes-mellitus
#16
Erik Staffa, Vladan Bernard, Luboš Kubíček, Robert Vlachovský, Daniel Vlk, Vojtěch Mornstein, Robert Staffa
Foot complications in persons with diabetes mellitus (DM) are associated with substantial costs and loss of quality of life. Increasing evidence suggests changes in skin temperature, measured using an infrared thermographic system (IRT), may be a predictor of foot ulcer development in patients with DM. The purpose of this case study is to describe the long-term IRT findings and overall clinical outcomes of a patient with DM and peripheral vascular disease. Foot temperature measurements using IRT were obtained slightly more than 1 year before and immediately following endovascular treatment of a 76-year-old man, a nonsmoker with type 2 DM, hypertension, and ischemic heart disease with cardiac arrhythmia...
April 2016: Ostomy/wound Management
https://www.readbyqxmd.com/read/27064366/use-of-smartphone-attached-mobile-thermography-assessing-subclinical-inflammation-a-pilot-study
#17
COMPARATIVE STUDY
T Kanazawa, G Nakagami, T Goto, H Noguchi, M Oe, T Miyagaki, A Hayashi, S Sasaki, H Sanada
OBJECTIVE: To verify the reliability and validity of FLIR ONE, a device connected to a smartphone, for the assessment of inflammation based on relative temperature increase compared with the thermography routinely used in pressure ulcer (PU) and diabetic foot assessment. METHOD: Participants in this pilot cross-sectional observational study were recruited from the patients in the PU team rounds and the diabetic foot outpatient clinic at the university hospital in January 2015...
April 2016: Journal of Wound Care
https://www.readbyqxmd.com/read/26983066/risk-factors-associated-with-pressure-ulcer-formation-in-critically-ill-cardiac-surgery-patients-a-systematic-review
#18
Aditi D Rao, Ave M Preston, Robyn Strauss, Rebecca Stamm, Demetra C Zalman
BACKGROUND: Cardiac surgery patients are among those most at risk for developing pressure ulcers (PUs), with a reported incidence as high as 29.5%. Although numerous studies documenting PU risk factors and prevention strategies exist, the availability of literature examining risk factors specific to the cardiac surgery population is limited. AIM: A systematic review was completed that aimed to identify the risk factors associated with PU development in critically ill, adult, cardiac surgery patients...
May 2016: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/26562377/microcirculatory-responses-of-sacral-tissue-in-healthy-individuals-and-inpatients-on-different-pressure-redistribution-mattresses
#19
S Bergstrand, U Källman, A-C Ek, M Engström, M Lindgren
OBJECTIVE: The aim of this study was to explore the interaction between interface pressure, pressure-induced vasodilation, and reactive hyperaemia with different pressure-redistribution mattresses. METHOD: A cross-sectional study was performed with a convenience sample of healthy young individuals, and healthy older individuals and inpatients, at a university hospital in Sweden. Blood flow was measured at depths of 1mm, 2mm, and 10mm using laser Doppler flowmetry and photoplethysmography...
August 2015: Journal of Wound Care
https://www.readbyqxmd.com/read/26467347/innovations-in-plantar-pressure-and-foot-temperature-measurements-in-diabetes
#20
S A Bus
Plantar pressure and temperature measurements in the diabetic foot primarily contribute to identifying abnormal values that increase risk for foot ulceration, and they are becoming increasingly more integrated in clinical practice and daily life of the patient. While plantar pressure measurements have long been present, only recently evidence shows their importance in ulcer prevention, as a data-driven approach to therapeutic footwear provision. The long-term monitoring of plantar pressures with the option to provide feedback, when alarming pressure levels occur, is a promising development in this area, although more technical and clinical validation is required...
January 2016: Diabetes/metabolism Research and Reviews
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