Cristina Villanueva-Bueno, Elena Montecatine-Alonso, Francisco Jiménez-Parrilla, Cecilia M Fernández-Llamazares, Silvia Manrique-Rodríguez, Elena Zamora-Flores, Elisenda Dolz, Aurora Fernández-Polo, Félix Catillo-Salinas, Juanjo Comuñas, Carmen Gallego-Fernández, María González-López, María-Teresa Gómez-Trevecedo Calvo, Rocío Gázquez-Pérez, Concepción Álvarez Del Vayo-Benito, Maria-Victoria Gil-Navarro
BACKGROUND: Antimicrobial defined daily dose (DDD), a standardized metric to assess antimicrobial consumption in adult population, has limitations hampering its use in neonatal patients. This study proposes an alternative DDD design applicable for neonates. METHODS: Neonates (<1 month-old) from 6 Spanish hospitals during a 12-months period were included. Weight and weeks gestational age of each neonate were the variables collected. DDD (g) for each antimicrobial was calculated by multiplying the obtained weight times the recommended dose (mg/kg) of the antimicrobial for the most common infectious indication selected by the Delphi method...
June 25, 2021: Enfermedades infecciosas y microbiologia clinica