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Cervical disc disease

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https://www.readbyqxmd.com/read/28525492/degenerative-cervical-disc-disease-long-term-changes-in-sagittal-alignment-and-their-clinical-implications-after-cervical-interbody-fusion-cage-subsidence-a-prospective-study-with-standalone-lordotic-tantalum-cages
#1
Félix Tomé-Bermejo, Julián A Morales-Valencia, Javier Moreno-Pérez, Juan Marfil-Pérez, Elena Díaz-Dominguez, Angel R Piñera, Luis Alvarez
STUDY DESIGN: A retrospective, observational study of prospectively collected outcomes. OBJECTIVE: To investigate the long-term clinical course of anterior cervical discectomy and fusion with interbody fusion cages (ACDF-IFC) with lordotic tantalum implants and to correlate the radiologic findings with the clinical outcomes, with special emphasis on the significance and the influence of implant subsidence. SUMMARY OF BACKGROUND DATA: Cage subsidence is the most frequently reported complication after ACDF-IFC...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525471/cervical-disk-replacement-with-discover-versus-fusion-in-a-single-level-cervical-disk-disease-a-prospective-single-center-randomized-trial-with-a-minimum-2-year-follow-up
#2
Marjan Rožanković, Sergej M Marasanov, Miroslav Vukić
STUDY DESIGN: Prospective randomized study. OBJECTIVE: To compare the clinical outcome after Discover arthroplasty versus anterior cervical discectomy and fusion (ACDF) in patients treated for symptomatic single-level cervical disk disease. SUMMARY OF BACKGROUND DATA: ACDF is still the gold standard for surgical treatment of cervical spine degenerative disk disease. However, results of many studies suggest that it may cause degenerative changes at levels immediately above and below the fusion, known as adjacent segment degenerative disease...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28503982/anxiety-and-depression-affect-pain-drawings-in-cervical-degenerative-disc-disease
#3
Anna MacDowall, Yohan Robinson, Martin Skeppholm, Claes Olerud
INTRODUCTION: Pain drawings have been frequently used in the preoperative evaluation of spine patients. Until now most investigations have focused on low back pain patients, even though pain drawings are used in neck pain patients as well. The aims of this study were to investigate the pain drawing and its association to preoperative demographics, psychological impairment, and pain intensity. METHODS: We carried out a post hoc analysis of a randomized controlled trial, comparing cervical disc replacement to fusion for radiculopathy related to degenerative disc disease...
May 15, 2017: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/28501956/an-in-vitro-evaluation-of-sagittal-alignment-in-the-cervical-spine-after-insertion-of-supraphysiologic-lordotic-implants
#4
Donald J Blaskiewicz, Jeffrey E Harris, Patrick P Han, Alexander W Turner, Gregory M Mundis
PURPOSE: Cervical spine malalignment can develop as a consequence of degenerative disc disease or following spinal surgery. When normal sagittal alignment of the spine is disrupted, further degeneration may occur adjacent to the deformity. The purpose of this study was to investigate changes in lordosis and sagittal alignment in the cervical spine after insertion of supraphysiologic lordotic implants. METHODS: Eight cadaveric cervical spines (Occiput-T1) were tested...
May 13, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28498027/asthma-and-early-herniated-intervertebral-disc-disease
#5
Cheng-Di Chiu, Hsuan-Ju Chen, Hean-Pat Saw, Nai-Wei Yao, Hung-Rong Yen, Chia-Hung Kao
BACKGROUND: The etiology of herniated intervertebral disc (HIVD) disease in children and adolescents is multifactorial and not merely related to disc degeneration. Therefore, in the present study, we investigated the relationship between young asthma patients and the risk of early HIVD disease in a population under 30 years of age. MATERIALS AND METHODS: Data from the National Health Insurance Research Database (NHIRD) of Taiwan were used to conduct a retrospective longitudinal cohort study...
May 12, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28496111/indirect-meta-analysis-comparing-clinical-outcomes-of-total-cervical-disc-replacements-with-fusions-for-cervical-degenerative-disc-disease
#6
Bin Xu, Jian-Xiong Ma, Jin-Hui Tian, Long Ge, Xin-Long Ma
Anterior cervical discectomy and fusion (ACDF) and total cervical disc replacement (TDR) are considered effective treatments for patients with cervical degenerative disc disease (CDDD). An indirect meta-analysis including 19 randomized controlled trials (5343 patients) was conducted to compare the clinical outcomes of ACDF with TDR. Primary outcomes including functional indicators (NDI [neck disability index] score, neurological success and patient satisfaction), secondary outcomes including surgical outcomes (operation time, blood loss and length of stay) and secondary surgical procedures (secondary surgery at an adjacent level, secondary surgery at the index level, secondary surgery at both levels, removal, reoperation, revision and supplemental fixation) were included in the study...
May 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28488093/trends-analysis-of-surgical-procedures-for-cervical-degenerative-disc-disease-and-myelopathy-in-patients-with-tobacco-use-disorder
#7
Phillip Grisdela, Zorica Buser, Anthony D'Oro, Permsak Paholpak, John C Liu, Jeffrey C Wang
PURPOSE: This study defined the incidence and trends of surgeries performed for patients with cervical disc degeneration with and without tobacco use disorder (TUD). METHODS: This study utilized the Humana Inc. database between 2007 and 2013 to identify patients with cervical disc degeneration with or without myelopathy. International Classification of Diseases, ninth revision (ICD-9) and Current Procedural Terminology (CPT) codes determined the initial diagnosis of disc degeneration, myelopathy status and TUD, whether patients received surgery, and TUD status at surgery...
May 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28473949/minimally-invasive-anterior-cervical-discectomy-without-fusion-to-treat-cervical-disc-herniations-in-patients-with-previous-cervical-fusions
#8
Robert E Jacobson, Michelle Granville, Aldo Berti
Adjacent level cervical disc disease and secondarily progressive disc space degeneration that develops years after previously successful anterior cervical fusion at one or more levels is a common, but potentially complex problem to manage. The patient is faced with the option of further open surgery which involves adding another level of disc removal with fusion, posterior decompression, and stabilization, or possibly replacing the degenerated disc with an artificial disc construct. These three cases demonstrate that some patients, especially after minor trauma, may have small herniated discs as the cause for their new symptoms rather than progressive segmental degeneration...
April 3, 2017: Curēus
https://www.readbyqxmd.com/read/28458586/the-roi-c-zero-profile-anchored-spacer-for-anterior-cervical-discectomy-and-fusion-biomechanical-profile-and-clinical-outcomes
#9
Michael N Bucci, Dennis Oh, R Scott Cowan, Reginald J Davis, Robert J Jackson, Dwight S Tyndall, Daniel Nehls
INTRODUCTION: Anterior cervical discectomy and fusion (ACDF) has been the gold standard for treating cervical degenerative disc disease (cDDD). The use of anterior plates in ACDF poses an increased risk of complications such as screw or plate dislodgement, soft tissue injury, esophagus perforation, and dysphagia. The ROI-C™ implant system consists of a zero-profile interbody fusion cage with self-locking plates designed for stand-alone fusion without external plates or screws. OBJECTIVE: The purpose of this report is to describe the ROI-C™ implant system with VerteBRIDGE™ anchor plates, including indications for use, surgical technique, preclinical testing, and clinical study results...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/28456670/there-is-no-increased-risk-of-adjacent-segment-disease-at-the-cervico-thoracic-junction-following-an-anterior-cervical-discectomy-and-fusion-to-c7
#10
Philip K Louie, Steven M Presciutti, Stephanie E Iantorno, Daniel D Bohl, Kevin Shah, Grant D Shifflett, Howard S An
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a very common operative intervention for the treatment of cervical spine degenerative disease in those who have failed non-operative measures. However, studies examining long-term follow up on patients who underwent ACDF reveal evidence of radiographic and clinical degenerative disc disease at the levels adjacent to the fusion construct. Consistent with other junctional regions of the spine, the cervicothoracic junction (CTJ) has significant morphological variations...
April 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28441686/surgical-and-functional-outcomes-after-multilevel-cervical-fusion-for-degenerative-disc-disease-compared-with-fusion-for-radiculopathy-a-study-of-workers-compensation-population
#11
Mhamad Faour, Joshua T Anderson, Arnold R Haas, Rick Percy, Stephen T Woods, Uri M Ahn, Nicholas U Ahn
STUDY DESIGN: Retrospective cohort comparative study. OBJECTIVE: To evaluate presurgical and surgical factors that affect return to work (RTW) status after multilevel cervical fusion, and to compare outcomes after multilevel cervical fusion for degenerative disc disease (DDD) versus radiculopathy. SUMMARY OF BACKGROUND DATA: Cervical fusion provides more than 90% of symptomatic relief for radiculopathy and myelopathy. However, cervical fusion for DDD without radiculopathy is considered controversial...
May 1, 2017: Spine
https://www.readbyqxmd.com/read/28437035/the-association-between-oral-examination-findings-and-the-computed-tomographic-appearance-of-the-equine-temporomandibular-joint
#12
J L Carmalt, H Simhofer, A Bienert-Zeit, J E Rawlinson, C L Waldner
BACKGROUND: The temporomandibular joint (TMJ) forms the junction between the maxilla and mandible. Movement of the jaw and resulting masticatory forces have been extensively studied in the horse; however, less is known about the inter-relationship between this joint and oral and dental pathology. OBJECTIVES: To determine the association between specific oral and dental pathologies and anatomical variations of the TMJ imaged with computed tomography (CT) in horses with asymptomatic TMJs...
April 24, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28422837/multilevel-cervical-disc-replacement-versus-multilevel-anterior-discectomy-and-fusion-a-meta-analysis
#13
REVIEW
Ting-Kui Wu, Bei-Yu Wang, Yang Meng, Chen Ding, Yi Yang, Ji-Gang Lou, Hao Liu
BACKGROUND: Cervical disc replacement (CDR) has been developed as an alternative surgical procedure to anterior cervical discectomy and fusion (ACDF) for the treatment of single-level cervical degenerative disc disease. However, patients with multilevel cervical degenerative disc disease (MCDDD) are common in our clinic. Multilevel CDR is less established compared with multilevel ACDF. This study aims to compare the outcomes and evaluate safety and efficacy of CDR versus ACDF for the treatment of MCDDD...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28387616/long-term-clinical-and-radiographic-outcomes-of-the-prestige-lp-artificial-cervical-disc-replacement-at-2-levels-results-from-a-prospective-randomized-controlled-clinical-trial
#14
Todd H Lanman, J Kenneth Burkus, Randall G Dryer, Matthew F Gornet, Jeffrey McConnell, Scott D Hodges
OBJECTIVE The aim of this study was to assess long-term clinical safety and effectiveness in patients undergoing anterior cervical surgery using the Prestige LP artificial disc replacement (ADR) prosthesis to treat degenerative cervical spine disease at 2 adjacent levels compared with anterior cervical discectomy and fusion (ACDF). METHODS A prospective, randomized, controlled, multicenter FDA-approved clinical trial was conducted at 30 US centers, comparing the low-profile titanium ceramic composite-based Prestige LP ADR (n = 209) at 2 levels with ACDF (n = 188)...
April 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28378073/kinematics-of-cervical-segments-c5-c6-in-axial-rotation-before-and-after-total-disc-arthroplasty
#15
Martin Michael Wachowski, Jan Weiland, Markus Wagner, Riccardo Gezzi, Dietmar Kubein-Meesenburg, Hans Nägerl
PURPOSE: The kinematical properties of C5/C6 segments in axial rotation are evaluated before and after total disc arthroplasty (TDA) with PRESTIGE(®)-and BRYAN(®) Cervical Disc (Medtronic) under flexion/extension as parameters and compared with those of C3/C4. METHODS: Eight human segments were stimulated by triangularly varying, axially directed torque (T z(t)) under compressing static axial preloads. Using a 6D-measuring device with high resolution, the response of segmental motion was characterized by the instantaneous helical axis (IHA)...
April 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28368529/understanding-united-states-investigational-device-exemption-studies-clinical-relevance-and-importance-for-healthcare-economics
#16
Jared D Ament, Scott Mollan, Krista Greenan, Tamar Binyamin, Kee D Kim
INTRODUCTION: The US Food and Drug Administration allows a previously unapproved device to be used clinically to collect safety and effectiveness data under their Investigational Device Exemption (IDE) category. The process usually falls under 3 different trial categories: noninferiority, equivalency, and superiority. To confidently inform our patients, understanding the basic concepts of these trials is paramount. The purpose of this manuscript was to provide a comprehensive review of these topics using recently published IDE trials and economic analyses of cervical total disc replacement as illustrative examples...
June 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28358860/discover-cervical-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion-in-symptomatic-cervical-disc-diseases-a-meta-analysis
#17
Lei Shangguan, Guang-Zhi Ning, Yu Tang, Zhe Wang, Zhuo-Jing Luo, Yue Zhou
OBJECTIVE: Symptomatic cervical disc disease (SCDD) is a common degenerative disease, and Discover artificial cervical disc, a new-generation nonconstrained artificial disk, has been developed and performed gradually to treat it. We performed this meta-analysis to compare the efficacy and safety between Discover cervical disc arthroplasty (DCDA) and anterior cervical discectomy and fusion (ACDF) for SCDD. METHODS: An exhaustive literature search of PubMed, EMBASE, and the Cochrane Library was conducted to identify randomized controlled trials that compared DCDA with ACDF for patients suffering SCDD...
2017: PloS One
https://www.readbyqxmd.com/read/28353143/cervical-disc-replacement-surgery-biomechanical-properties-postoperative-motion-and-postoperative-activity-levels
#18
REVIEW
Alfred Pisano, Melvin Helgeson
PURPOSE OF REVIEW: Cervical disc arthroplasty (CDA) is an evolving technique used in the treatment of cervical disc disease. To remain up to date on studies regarding its efficacy, we sought to answer three questions: What do biomechanical studies demonstrate in regard to the kinematics of CDA? How does CDA affect cervical motion? What are the postoperative activity levels of patients after cervical disc arthroplasty? RECENT FINDINGS: 1) In regard to biomechanics, recent data suggests that CDA maintains motion while possibly altering facet biomechanics...
March 28, 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28348897/ace-inhibitor-induced-angioedema-following-cervical-spine-surgery
#19
Faris Hannoodi, Hussam Sabbagh
Angioedema is a well-known side effect of angiotensin converting enzyme inhibitors (ACEi). However, ACE inhibitors induced angioedema after cervical surgery is a rare condition. They result in increased levels of circulating bradykinins. Rare cases of angioedema following local trauma in patients using ACE inhibitors have been published. We present such a case. A 54-year-old Caucasian female with a history significant for hypertension, controlled with lisinopril, was admitted for routine cervical spine surgery...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28343313/spontaneous-cervical-intradural-disc-herniation-presenting-with-brown-s%C3%A3-quard-and-horner-s-syndrome-lesson-learned-from-a-very-unique-case
#20
Irene Baudracco, Gordan Grahovac, Vittorio M Russo
PURPOSE: Cervical spontaneous intradural disc herniation (IDH) is an extremely rare condition. We describe a unique case of a patient presenting with a Brown-Séquard syndrome (BSS) and Horner's syndrome (HS). This study aimed to report an unusual case of spontaneous cervical intradural disc herniation that presented with Horner's and Brown-Séquard syndrome (BSS) and discuss difficulties in preoperative diagnosis and treatment difficulties of intradural cervical disc. METHODS: Notes and images review, and analysis of the relevant literature...
March 25, 2017: European Spine Journal
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