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Cervical disc disease

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https://www.readbyqxmd.com/read/29325196/ventral-slot-surgery-to-manage-cervical-intervertebral-disc-disease-in-three-cats
#1
Abbe Harper Crawford, Rodolfo Cappello, Akash Alexander, Steven De Decker
OBJECTIVE:  This case series describes the clinical presentation, management and outcome of three cats diagnosed with cervical intervertebral disc disease that underwent decompressive ventral slot surgery. METHODS:  This is a retrospective case series evaluating client-owned cats undergoing a ventral slot surgical procedure to manage cervical intervertebral disc disease (n = 3). RESULTS:  A routine ventral slot surgery was performed in each case without complication, resulting in postoperative neurological improvement in all three cases...
January 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29322313/implantation-of-an-empty-polyetheretherketone-cage-in-anterior-cervical-discectomy-and-fusion-a-prospective-randomised-controlled-study-with-2%C3%A2-years-follow-up
#2
Shang-Wen Feng, Ming-Chau Chang, Po-Hsin Chou, Hsi-Hsien Lin, Shih-Tien Wang, Chien-Lin Liu
PURPOSE: To compare the clinical outcomes, radiographic results and fusion rate of ACDF between empty PEEK cages and PEEK cages packed with β-tricalcium phosphate. METHODS: Forty-five patients were prospectively enrolled with cervical degenerative disc disease who requiring ACDF with a PEEK cage. 23 patients were randomised to the study group (empty cages) and 22 patients were in the control group (cages filled with β-tricalcium phosphate). Both patient groups were fixed with a cervical locking plate...
January 10, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29315119/cervical-artificial-disc-replacement-with-discover-prosthesis-does-not-reduce-the-midterm-risk-of-heterotopic-ossification-results-of-a-cohort-study
#3
Jinhao Miao, Ye Shen, Chao Li, Lei Fang, Lei Zhang, Xiangyi Zhang, Yiman Li, Yong Kuang
STUDY DESIGN: A prospective cohort study with 79 patients. OBJECTIVE: To analyze the midterm incidence of heterotopic ossification (HO) after cervical artificial disc replacement with Discover prosthesis in treatment of cervical degenerative disc disease. MATERIALS AND METHODS: A cohort of 79 patients with 102 Discover prostheses (56 monosegment and 23 bisegments) was evaluated. Clinical and radiographic follow-up was performed. The performance of HO of the operative segments was assessed annually after the operation for 4 years...
January 8, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29305455/the-effectiveness-of-anterior-cervical-decompression-and-fusion-for-the-relief-of-dizziness-in-patients-with-cervical-spondylosis-a-multicentre-prospective-cohort-study
#4
B Peng, L Yang, C Yang, X Pang, X Chen, Y Wu
AIMS: Cervical spondylosis is often accompanied by dizziness. It has recently been shown that the ingrowth of Ruffini corpuscles into diseased cervical discs may be related to cervicogenic dizziness. In order to evaluate whether cervicogenic dizziness stems from the diseased cervical disc, we performed a prospective cohort study to assess the effectiveness of anterior cervical discectomy and fusion on the relief of dizziness. PATIENTS AND METHODS: Of 145 patients with cervical spondylosis and dizziness, 116 underwent anterior cervical decompression and fusion and 29 underwent conservative treatment...
January 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29304802/evaluation-of-the-influence-of-kyphosis-and-scoliosis-on-intervertebral-disc-extrusion-in-french-bulldogs
#5
Maria Claudia C M Inglez de Souza, Richard Ryan, Gert Ter Haar, Rowena M A Packer, Holger A Volk, Steven De Decker
BACKGROUND: Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and intervertebral disc degeneration. It is however unknown if an abnormal spinal curvature also predisposes dogs to develop clinically relevant intervertebral disc herniations. The aim of this study was to evaluate if the occurrence of thoracic vertebral malformations, kyphosis or scoliosis would be associated with a higher prevalence of cervical or thoracolumbar intervertebral disc extrusion in French bulldogs...
January 5, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29288377/outcomes-of-the-bryan-cervical-disc-replacement-fifteen-year-follow-up
#6
Vincent Pointillart, Jean-Etienne Castelain, Pierre Coudert, Derek Thomas Cawley, Olivier Gille, Jean-Marc Vital
BACKGROUND: The CTDR is a technique that treats cervical disc degenerative disease. Initial shorter-term studies showed good clinical and radiological results. PURPOSE: To assess the clinical and radiological results of Bryan cervical disc replacement (Medtronic Sofamor Danek Inc., Memphis, TN) at 15-year follow-up. RESULTS: This prospective study included 20 patients who underwent 22 CTDR, comprising a single-level procedure in 14 patients and two-level procedures in six patients...
December 29, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29283093/anterior-cervical-disc-fusion-does-not-affect-the-presence-of-cervical-vestibular-evoked-myogenic-potential
#7
Ioannis Kastanioudakis, Panagiotis Saravakos, Andreas Zigouris, Vasileios Ragos, Oliver Reichel, Nafsika Ziavra
OBJECTIVE: Cervical spondylosis and cervical disk herniation are the most frequent forms of degenerative disease in the cervical spine. Surgical treatment mainly includes anterior cervical disk fusion. However, information concerning vestibular-evoked myogenic potential (VEMP) recording in patients undergoing cervical spine surgery is limited. The present prospective study aimed to investigate the effect of anterior disk fusion surgery on cervical VEMP (cVEMP) parameters. MATERIALS AND METHODS: Twenty-five patients were enrolled in this study, and 20 patients (10 men and 10 women) completed cVEMP testing...
December 14, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29279758/the-role-of-dynamic-magnetic-resonance-imaging-in-cervical-spondylotic-myelopathy
#8
REVIEW
John Paul Kolcun, Lee Onn Chieng, Karthik Madhavan, Michael Y Wang
Dynamic spinal cord compression has been investigated for several years, but until the advent of open MRI, the use of dynamic MRI (dMRI) did not gain popularity. Several publications have shown that cervical cord compression is both static and dynamic. On many occasions the evaluation of cervical spondylotic myelopathy (CSM) is straightforward, but patients are frequently encountered with a significantly worse clinical examination than would be suggested by radiological images. In this paper, we present an extensive review of the literature in order to describe the importance of dMRI in various settings and applications...
December 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29245217/efficacy-and-safety-of-mobi-c-cervical-artificial-disc-versus-anterior-discectomy-and-fusion-in-patients-with-symptomatic-degenerative-disc-disease-a-meta-analysis
#9
Hui Lu, Lihua Peng
BACKGROUND: Total disc replacement (TDR) using Mobi-C cervical artificial disc might be promising to treat symptomatic degenerative disc disease. However, the results remained controversial. We conducted a systematic review and meta-analysis to compare the efficacy and safety of Mobi-C cervical artificial disc and anterior cervical discectomy and fusion (ACDF) in patients with symptomatic degenerative disc disease. METHODS: PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systematically searched...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29243996/validation-of-the-visual-analog-scale-in-the-cervical-spine
#10
Anna MacDowall, Martin Skeppholm, Yohan Robinson, Claes Olerud
OBJECTIVE The visual analog scale (VAS) is frequently used to measure treatment outcome in patients with cervical spine disorders. The minimum clinically important difference (MCID) is the smallest change in a score that has clinical importance to the patient. Although it has been established for other medical fields, knowledge of the VAS MCID for the cervical spine is sparse, and it has rarely been considered in relation to measurement noise. The goals in this study were as follows: 1) to validate the VAS-neck and VAS-arm instruments for the cervical spine (e...
December 15, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29222937/preoperative-t1-slope-as-a-predictor-of-change-in-cervical-alignment-and-range-of-motion-after-cervical-disc-arthroplasty
#11
Jianhui Zhao, Rui Jiang, Yuhui Yang, Rui Gu, Zhongli Gao, Jianlin Xiao, Shangjun Chen, Modi Yang
BACKGROUND This study analyzed the effect of preoperative T1 slope on cervical alignment and range of motion (ROM) after cervical disc arthroplasty (CDA) in patients with cervical degenerative disease. MATERIAL AND METHODS This retrospective study included 32 patients with single-level symptomatic cervical disc disease who underwent CDA with the Mobi-C cervical disc prosthesis and had a mean follow-up of 26.8±6.4 months. Standing lateral, flexion, and extension X-rays of the cervical spine were obtained preoperatively and postoperatively at 24-month follow-up...
December 9, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29220729/comparison-of-dynamic-cervical-implant-versus-anterior-cervical-discectomy-and-fusion-for-the-treatment-of-single-level-cervical-degenerative-disc-disease-a-five-year-follow-up
#12
Ce Zhu, Xi Yang, Lei Wang, Bo-Wen Hu, Li-Min Liu, Lin-Nan Wang, Hao Liu, Yue-Ming Song
OBJECTIVE: To compare clinical and radiographic outcomes of dynamic cervical implant(DCI) with anterior cervical discectomy and fusion(ACDF) in the treatment of single-level cervical degenerative disc disease (CDDD) 5 years after surgery. PATIENTS AND METHODS: Forty-three patients with DCI were matched one-to-one with patients with ACDF based on age, gender, and operative segment in this retrospective study. All patients had been followed up for more than 5 years...
December 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29216503/clinical-and-radiographic-comparison-of-cervical-disc-arthroplasty-with-prestige-lp-disc-and-anterior-cervical-fusion-a-minimum-6-year-follow-up-study
#13
Junfeng Zeng, Hao Liu, Beiyu Wang, Yuxiao Deng, Chen Ding, Hua Chen, Yi Yang, Ying Hong, Ning Ning
OBJECTIVES: To retrospectively compare the long-term clinical and radiographic outcomes of cervical disc arthroplasty (CDA) with Prestige-LP Disc and anterior cervical discectomy and fusion (ACDF) for single-level cervical degenerative disc disease. PATIENTS AND METHODS: Ninety-eight patients (45 CDA and 53 ACDF) with a minimum 6-year follow-up were included. Clinical evaluations included Japanese Orthopedic Association (JOA), visual analogue scale (VAS), and Neck Disability Index (NDI) scores...
December 4, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29204735/inflammaging-in-cervical-and-lumbar-degenerated-intervertebral-discs-analysis-of-proinflammatory-cytokine-and-trp-channel-expression
#14
Aleksandra Sadowska, Ermioni Touli, Wolfgang Hitzl, Helen Greutert, Stephen J Ferguson, Karin Wuertz-Kozak, Oliver N Hausmann
PURPOSE: To investigate and compare the occurrence of inflammatory processes in the sites of disc degeneration in the lumbar and cervical spine by a gene array and subsequent qPCR and to investigate the mechanistic involvement of transient receptor potential channels TRPC6 and TRPV4. METHODS: The gene expression of inflammatory cytokines and TRP channels was measured in human disc samples obtained from patients undergoing discectomy at the cervical (n = 24) or lumbar (n = 27) spine for degenerative disc disease (DDD) and disc herniation (DH) and analyzed for differences with regard to spinal level, IVD degeneration grade, Modic grade, age, sex, disc region and surgical extent...
December 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29197741/exploration-about-changes-of-il-10-nf-%C3%AE%C2%BAb-and-mmp-3-in-a-rat-model-of-cervical-spondylosis
#15
Jianjian Yin, Kewei Ren, Yongjing Huang, Gongming Gao, Luming Nong, Nanwei Xu
OBJECTIVES: To investigate the relationship and mechanism between IL-10, NF-κB and MMP-3 in cervical degenerative disease induced by unbalanced dynamic and static forces in rats. METHODS: Sixty Sprague Dawley rats were randomized into test (n=45) and control (n=15) groups, which were randomly subdivided into three groups corresponding to one-month, three-month and six-month post-operation. Test group included 10, 15, 20 rats at corresponding postoperative stage and control group had five rats at each time point...
November 30, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/29189218/adjacent-level-degeneration-bryan-total-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion
#16
Justin Miller, Rick Sasso, Paul Anderson, K Daniel Riew, Austin McPhilamy, Thomas Gianaris
STUDY DESIGN: Prospective randomized, 2-center, clinical trial. OBJECTIVE: To prospectively compare adjacent level degeneration between the Bryan Cervical Disc Prosthesis and anterior cervical discectomy and fusion (ACDF), and assess the reliability of our measurements utilizing a method not previously described. SUMMARY OF BACKGROUND DATA: ACDF is a reliable and proven procedure for the treatment of radiculopathy and/or myelopathy. Despite a successful track record several limitations including adjacent segment degeneration/disease, loss of viscoelastic disc properties, perioperative immobilization, graft site morbidity, pseudarthrosis, and plating complications have been identified...
November 16, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29180636/anterior-cervical-discectomy-and-fusion-surgery-versus-total-disc-replacement-a-comparative-study-with-minimum-of-10-year-follow-up
#17
Si-Dong Yang, Yan-Bo Zhu, Suo-Zhou Yan, Jun Di, Da-Long Yang, Wen-Yuan Ding
Based on long-term follow-ups, this study was designed to investigate the incidence and risk factors for postoperative adjacent segment degeneration (ASD) after anterior cervical discectomy and fusion (ACDF) or total disc replacement (TDR) in treating cervical degenerative diseases. Between January 2000 and December 2005, 108 cases undergoing ACDF and 78 undergoing TDR, were enrolled into this study. All medical records were retrospectively collected. Every patient was followed up at least 10 years. Outcome assessment included visual analogue scale (VAS) score, Neck Disability Index (NDI) score, Japanese Orthopaedic Association (JOA) score, and radiographic parameters...
November 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29142629/a-prospective-study-with-cage-only-or-cage-with-plate-fixation-in-anterior-cervical-discectomy-and-interbody-fusion-of-one-and-two-levels
#18
Sam Yeol Kim, Seung Hwan Yoon, Dokeun Kim, Chang Hyun Oh, Seyang Oh
Objective: The authors prospectively analyzed the effect of one-level or two-level anterior cervical discectomy and fusion (ACDF), comparing stand-alone cages and cage-with-plate fixation constructs with respect to clinical outcomes and radiologic changes. Methods: A total of 84 patients who underwent one-level (n=52) or two-level ACDF (n=32) for cervical disc disease and who completed 2 years of follow-up were included in this study. The patients were divided by cervical level and grouped into ACDF-Cage-only and ACDF-Cage-with-plate groups...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29142627/a-comparison-of-anterior-cervical-discectomy-and-fusion-versus-fusion-combined-with-artificial-disc-replacement-for-treating-3-level-cervical-spondylotic-disease
#19
Seo-Ryang Jang, Sang-Bok Lee, Kyoung-Suok Cho
Objective: The purpose of this study is to evaluate the efficacy and safety of 3-level hybrid surgery (HS), which combines fusion and cervical disc replacement (CDR), compared to 3-level fusionin patient with cervical spondylosis involving 3 levels. Methods: Patients in the anterior cervical discectomy and fusion (ACDF) group (n=30) underwent 3-level fusion and the HS group (n=19) underwent combined surgery with fusion and CDR. Clinical outcomes were evaluated using the visual analogue scale for the arm, the neck disability index (NDI), Odom criteria and postoperative complications...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29069048/predictive-factors-associated-with-neck-pain-in-patients-with-cervical-disc-degeneration-a-cross-sectional-study-focusing-on-modic-changes
#20
Lingde Kong, Weifeng Tian, Peng Cao, Haonan Wang, Bing Zhang, Yong Shen
The predictive factors associated with neck pain remain unclear. We conducted a cross-sectional study to assess predictive factors, especially Modic changes (MCs), associated with the intensity and duration of neck pain in patients with cervical disc degenerative disease.We retrospectively reviewed patients in our hospital from January 2013 to December 2016. Severe neck pain (SNP) and persistent neck pain (PNP) were the 2 main outcomes, and were assessed based on the numerical rating scale (NRS). Basic data, and also imaging data, were collected and analyzed as potential predictive factors...
October 2017: Medicine (Baltimore)
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