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Cervical disc disease

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https://www.readbyqxmd.com/read/28097889/titanium-cages-versus-autogenous-iliac-crest-bone-grafts-in-anterior-cervical-discectomy-and-fusion-treatment-of-patients-with-cervical-degenerative-diseases-a-systematic-review-and-meta-analysis
#1
Ming-Hao Shao, Fan Zhang, Jun Yin, Hao-Cheng Xu, Fei-Zhou Lyu
OBJECTIVE: A systematic review and partial meta-analysis is conducted to compare the efficacy and safety of anterior cervical decompression and fusion procedures employing either rectangular titanium cages or iliac crest autografts in patients suffering from cervical degenerative disc diseases. METHODS: Medline, PubMed, CENTRAL, and Google Scholar databases were searched until June 2015, using keywords cervical discectomy; bone transplantation; titanium cages; iliac crest autografts...
January 18, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28097260/arthroplasty-in-cervical-degenerative-disc-disease-fulfilling-its-long-term-promise
#2
EDITORIAL
Toon F M Boselie, Henk van Santbrink
No abstract text is available yet for this article.
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28061490/comparative-analysis-between-total-disc-replacement-and-posterior-foraminotomy-for-posterolateral-soft-disc-herniation-with-unilateral-radiculopathy-clinical-and-biomechanical-results-of-a-minimum-5-years-follow-up
#3
Kyoung-Tae Kim, Dae-Chul Cho, Joo-Kyung Sung, Young-Baeg Kim, Du Hwan Kim
OBJECTIVE: To compare the clinical outcomes and biomechanical effects of total disc replacement (TDR) and posterior cervical foraminotomy (PCF) and to propose relative inclusion criteria. METHODS: Thirty-five patients who underwent surgery between 2006 and 2008 were included. All patients had single-level disease and only radiculopathy. The overall sagittal balance and angle and height of a functional segmental unit (FSU; upper and lower vertebral body of the operative lesion) were assessed by preoperative and follow-up radiographs...
January 1, 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28040505/dlg1-polarity-protein-expression-associates-with-the-disease-progress-of-low-grade-cervical-intraepithelial-lesions
#4
Ana Laura Cavatorta, Alejandra Di Gregorio, Marina Bugnon Valdano, Federico Marziali, Mariela Cabral, Hebe Bottai, Jorge Cittadini, Ana Lia Nocito, Daniela Gardiol
Human Discs large tumour suppressor (DLG1) participates in regulating cell polarity and proliferation, suggesting an important connection between epithelial organization and cellular growth control. However, it was demonstrated that DLG1 could acquire oncogenic attributes in some specific contexts. In this work, we evaluated the expression of DLG1 and its contribution to the progress of cervical lesions in order to investigate a potential role of this polarity protein in human oncogenic processes. We analyzed cervical biopsies from women with low-grade squamous intraepithelial lesion (LSIL) diagnosis (n=30), for DLG1 expression by immunohistochemistry...
December 29, 2016: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/28032706/correlations-of-japanese-orthopaedic-association-scoring-systems-with-gait-parameters-in-patients-with-degenerative-spinal-diseases
#5
Chen-Fan Zheng, Yan-Cheng Liu, Yong-Cheng Hu, Qun Xia, Jun Miao, Ji-Dong Zhang, Kuan Zhang
OBJECTIVE: Japanese Orthopaedic Association (JOA) scoring systems were developed to evaluate the neurological function of patients with cervical or lumbar degeneration. As patient-based and multi-dimensional clinical evaluation tools, these systems should be capable of reflecting the walking disability of patients. The association between JOA scores and gait parameters, however, are not well characterized. The purpose of this study was to determine the correlations between JOA scores and gait parameters of patients with cervical spondylotic myelopathy (CSM) and lumbar intervertebral disc herniation (LDH)...
November 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28017756/a-clinical-comparison-of-anterior-cervical-plates-versus-stand-alone-intervertebral-fusion-devices-for-single-level-anterior-cervical-discectomy-and-fusion-procedures
#6
Ripul R Panchal, Kee D Kim, Robert Eastlack, John Lopez, Andrew Clavenna, Daina M Brooks, Gita Joshua
OBJECTIVE: To compare radiologic and clinical outcomes, including rates of dysphagia and dysphonia, using a no-profile stand-alone intervertebral spacer with integrated screw fixation versus an anterior cervical plate and spacer construct for single-level anterior cervical discectomy and fusion (ACDF) procedures. METHODS: This multicenter, randomized, prospective study included 54 patients with degenerative disc disease (DDD) requiring ACDF at a single level at C3-C7...
December 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28012081/the-norwegian-cervical-arthroplasty-trial-norcat-2-year-clinical-outcome-after-single-level-cervical-arthroplasty-versus-fusion-a-prospective-single-blinded-randomized-controlled-multicenter-study
#7
Jarle Sundseth, Oddrun Anita Fredriksli, Frode Kolstad, Lars Gunnar Johnsen, Are Hugo Pripp, Hege Andresen, Erling Myrseth, Kay Müller, Øystein P Nygaard, John-Anker Zwart
PURPOSE: Standard surgical treatment for symptomatic cervical disc disease has been discectomy and fusion, but the use of arthroplasty, designed to preserve motion, has increased, and most studies report clinical outcome in its favor. Few of these trials, however, blinded the patients. We, therefore, conducted the Norwegian Cervical Arthroplasty Trial, and present 2-year clinical outcome after arthroplasty or fusion. METHODS: This multicenter trial included 136 patients with single-level cervical disc disease...
December 23, 2016: European Spine Journal
https://www.readbyqxmd.com/read/28002363/comparison-of-outcomes-of-single-level-anterior-cervical-discectomy-with-fusion-and-single-level-artificial-cervical-disc-replacement-for-single-level-cervical-degenerative-disc-disease
#8
Praveen Kumar Pandey, Inder Pawar, Jyoti Gupta, Raaghav Rai Verma
STUDY DESIGN: A single-center, prospective comparative study of prospectively collected outcomes, with a minimum 12 months follow-up. OBJECTIVES: The primary purpose of the study is to investigate the clinical, functional, and radiological outcomes of cervical total disc replacement (CTDR) in comparison with anterior cervical discectomy and fusion (ACDF) in the treatment of single-level cervical disc degenerative disease, prospectively. SUMMARY OF BACKGROUND DATA: CTDR has recently been an alternative to ACDF in cervical disc degenerative disease to preserve the motion at the treated level...
January 1, 2017: Spine
https://www.readbyqxmd.com/read/28002345/comparison-of-the-more-than-5-year-clinical-outcomes-of-cervical-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion-a-protocol-for-a-systematic-review-and-meta-analysis-of-prospective-randomized-controlled-trials
#9
Min-Min Shao, Chun-Hui Chen, Zhong-Ke Lin, Xiang-Yang Wang, Qi-Shan Huang, Yong-Long Chi, Ai-Min Wu
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) was almost the "golden standard" technique in treatment of symptomatic cervical degenerative disc disease, however, it cause motion loss of the indexed level, increase the intradiscal pressure and motion of the adjacent levels, and may accelerate the degeneration of adjacent level. Cervical disc arthroplasty (CDA) was designed to preserve the motion of index level, avoid the over-activity of adjacent levels and reduce the degeneration of adjacent disc levels, the process of degeneration of adjacent level is very slowly, long term follow up studies should be conducted, this study aim to compare the more than 5 years' long-term clinical outcomes and safety between CDA and ACDF...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27997508/cost-variation-of-anterior-cervical-fusions-in-elderly-medicare-beneficiaries
#10
Varun Puvanesarajah, David J Kirby, Amit Jain, Brian C Werner, Hamid Hassanzadeh
STUDY DESIGN: Retrospective database review OBJECTIVE.: To determine how demographics and comorbid diagnoses influence hospital costs during admission for anterior cervical fusions (ACFs) in the elderly Medicare population. SUMMARY OF BACKGROUND DATA: Elective ACFs to treat degenerative cervical pathology are extremely common within the elderly population. Though it is well known that every patient has a significantly different medical profile that guides treatment and post-operative care, little information is available regarding how hospital costs vary from patient to patient...
December 16, 2016: Spine
https://www.readbyqxmd.com/read/27997506/response-commentary-to-the-editor-regarding-cervical-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion-for-incidence-of-symptomatic-adjacent-segment-disease-a-meta-analysis-of-prospective-randomized-controlled-trials-2016-spine-41-19-1493-502
#11
https://www.readbyqxmd.com/read/27994778/intrinsic-vertebral-markers-for-spinal-level-localization-in-anterior-cervical-spine-surgery-a-preliminary-report
#12
Deepak Kumar Jha, Anil Thakur, Mukul Jain, Arvind Arya, Chandrabhushan Tripathi, Rima Kumari, Suman Kushwaha
STUDY DESIGN: Prospective clinical study. PURPOSE: To observe the usefulness of anterior cervical osteophytes as intrinsic markers for spinal level localization (SLL) during sub-axial cervical spinal surgery via the anterior approach. OVERVIEW OF LITERATURE: Various landmarks, such as the mandibular angle, hyoid bone, thyroid cartilage, first cricoid ring, and C6 carotid tubercle, are used for gross cervical SLL; however, none are used during cervical spinal surgery via the anterior approach...
December 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27939974/revision-surgeries-following-artificial-disc-replacement-of-cervical-spine
#13
Jong-Beom Park, Han Chang, Jin S Yeom, Kyung-Soo Suk, Dong-Ho Lee, Jae Chul Lee
OBJECTIVE: We investigated causes and results of revision surgeries after artificial disc replacement of cervical spine (C-ADR). METHODS: Twenty-one patients (mean age: 52.8) who underwent revision surgery after C-ADR and who had a minimum 2-year of follow-up were included into this study. The mean time between the primary and revision surgeries was 21 months. During their primary surgeries, 14 patients underwent single level C-ADR, 2 two-level C-ADR, and 5 two-level hybrid surgery for 16 radiculopathy, 3 myelopathy, and 2 adjacent segment diseases...
December 8, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27916038/-mid-to-long-term-outcomes-of-cervical-disc-arthroplasty-for-symptomatic-cervical-disc-disease-a-meta-analysis
#14
S L Kan, B Yang, G Z Ning, S J Gao, J C Sun, S Q Feng
Objective: To compare the benefits and harms of cervical disc arthroplasty (CDA) with anterior cervical discectomy and fusion(ACDF) for symptomatic cervical disc disease at mid- to long-term follow-up. Methods: Electronic searches were made in PubMed, EMBASE, and the Cochrane Library for randomized controlled trials with at least 48 moths follow-up.Outcomes were reported as relative risk or standardized mean difference.Meta-analysis was carried out using Revman version 5.3 and Stata version 12.0. Results: Seven trials were included, involving 2 302 participants...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27902945/artificial-cervical-disc-replacement-with-the-prestige-lp-prosthesis-for-the-treatment-of-non-contiguous-2-level-cervical-degenerative-disc-disease-a-minimum-24-month-follow-up
#15
Tingkui Wu, Beiyu Wang, Chen Ding, Yang Meng, Jigang Lou, Yi Yang, Hao Liu
OBJECTIVE: We describe the features of non-contiguous 2-level cervical degenerative disc disease (NCDDD), investigate the safety and feasibility of artificial cervical disc replacement (ACDR) for the treatment of NCDDD, and expect that our study will provide spine surgeons with an alternative procedure for NCDDD. METHODS: Twenty-five patients with NCDDD received ACDR with a Prestige-LP prosthesis. Clinical outcomes were evaluated using the 36-Short Form (SF-36, Mental Component Summary [MCS] and Physical Component Summary [PCS]), Visual Analog Scale (VAS), Japanese Orthopedic Association (JOA), and Neck Disability Index (NDI) scores...
January 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27893652/correlation-between-t2-t2-star-relaxation-time-and-cervical-intervertebral-disc-degeneration-an-observational-study
#16
Minghua Huang, Yong Guo, Qiong Ye, Lei Chen, Kai Zhou, Qingjun Wang, Lixin Shao, Qinglei Shi, Chun Chen
PURPOSE: To demonstrate the potential benefits of T2 relaxation time of intervertebral discs (IVDs) regarding the detection and grading of degenerative disc disease using 3.0-T magnetic resonance imaging (MRI) in a clinical setting. MATERIALS AND METHODS: Cervical sagittal T2-weighted, T2 relaxation MRI was performed at 3.0-T in 61 subjects, covering discs C2-3 to C6-7. All discs were morphologically assessed based on the Pfirrmann grade, and regions of interests (ROIs) were drawn over the T2 mapping...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27888676/revision-surgery-for-cervical-artificial-disc-surgical-technique-and-clinical-results
#17
J Onken, A Reinke, J Radke, T Finger, S Bayerl, P Vajkoczy, B Meyer
OBJECTIVE: Cervical artificial disc replacement (C-ADR) was developed with the goal of preserving mobility of the cervical segment in patients with degenerative disc disease. So far, little is known about experiences with revision surgery and explantation of C-ADRs. Here, we report our experience with revision the third generation, Galileo-type disc prosthesis from a retrospective study of two institutions. PATIENTS AND METHODS: Between November 2008 and July 2016, 16 patients with prior implantation of C-ADR underwent removal of the Galileo-type disc prosthesis (Signus, Medizintechnik, Germany) due to a call back by industry...
January 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27879563/a-pilot-study-of-sequence-of-segmental-contributions-in-the-lower-cervical-spine-during-active-extension-and-flexion-healthy-controls-vs-cervical-degenerative-disc-disease-patients
#18
Toon Fm Boselie, Henk van Santbrink, Rob A de Bie, Henk van Mameren
STUDY DESIGN: A retrospective study in which, first, a definition of normal movement in the cervical spine is formulated. Second, use of this definition in differentiating between normal and abnormal movement of the cervical spine is evaluated. OBJECTIVE: To formulate a clear definition of the normal sequence of segmental contributions in the cervical spine during flexion/extension, and to evaluate the sensitivity, specificity, and reliability of sequence of segmental contributions analysis in differentiating between normal and abnormal movement of the cervical spine in healthy controls and patients with cervical degenerative disc disease (CDDD)...
November 22, 2016: Spine
https://www.readbyqxmd.com/read/27865820/adjacent-segment-disease-requiring-reoperation-in-cervical-total-disc-arthroplasty-a-literature-review-and-update
#19
REVIEW
Ki-Eun Chang, Martin H Pham, Patrick C Hsieh
OBJECTIVE: To evaluate the difference in rate of reoperation for adjacent segment disease (ASD) between anterior cervical decompression and fusion (ACDF) and total disc replacement (TDR). METHOD: A systematic review of literature was performed using PubMed, clinicaltrials.gov, and various other search engines. Nine studies met the inclusion criteria and were used to report an estimated overall rate of reoperation secondary to ASD for both ACDF and TDR. RESULTS: Forty-six clinical trials were identified after the initial search, and 9 studies met our inclusion criteria...
November 16, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27865095/assessment-and-determinants-of-spinal-pain-in-the-course-of-disc-disorders-treated-surgically
#20
Renata Jabłońska, Robert Ślusarz, Agnieszka Królikowska, Beata Haor, Magdalena Zając
BACKGROUND Intervertebral disc disease is defined as a complex of structural changes in the aftermath of disorders of mutual elements, the structure of which form the discus intervertebralis and the spinal canal. The present work assessed pain in patients who were surgically treated due to spinal discopathy and analyzed factors that determine the condition. MATERIAL AND METHODS The research was carried on a group of 187 patients diagnosed with discopathy of the lumbosacral and cervical segment. The data are discussed in the context of medical records and the Visual Analogue Scale used for pain assessment...
November 19, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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