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https://www.readbyqxmd.com/read/29452366/prevalence-and-incidence-of-anal-and-cervical-high-risk-human-papillomavirus-hpv-types-covered-by-current-hpv-vaccines-among-hiv-infected-women-in-the-study-to-understand-the-natural-history-of-hiv-aids-in-the-era-of-effective-therapy-the-sun-study
#1
Erna Milunka Kojic, Lois Conley, Tim Bush, Susan Cu-Uvin, Elizabeth R Unger, Keith Henry, John Hammer, Gerome Escota, Teresa M Darragh, Joel M Palefsky, John T Brooks, Pragna Patel
Background: Nonavalent (9v) human papilloma virus vaccine targets high-risk (HR)-HPV types 16, 18, 31, 33, 45, 52, 58, and low-risk 6, 11. We examined prevalence, incidence, and clearance of anal and cervical HR-HPV in HIV-infected women. Methods: From 2004-2006, the SUN Study enrolled 167 women from four US cities. Anal and cervical specimens were collected annually for cytology and identification of 37 HPV types; 14 HR include: 9v 16, 18, 31, 33, 45, 52, 58; non-9v 35, 39, 51, 56, 59, 66, 68...
February 14, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29446703/use-of-the-5-mm-endoscopic-stapler-for-ligation-of-fistula-in-laparoscopic-assisted-repair-of-anorectal-malformation
#2
Bethany J Slater, Saundra Kay, Steven S Rothenberg
OBJECTIVE: Laparoscopic anorectoplasty (LARRP) for the treatment of select anorectal malformations has gained popularity due to enhanced visualization of the fistula and the ability to place the rectum within the sphincter complex while minimizing division of muscles and the perineal incision. However, given the technical challenges and reported complications of ligation, a number of techniques have been described, including using clips, suture ligation, endoloops, or division without closure...
February 15, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29435742/information-needs-expressed-during-patient-oriented-oncology-consultations-quantity-variation-and-barriers
#3
Anesa Ahamad, Paul Wallner, Sharon Salenius, Rudi Ross, Eduardo Fernandez
High-quality oncology consultation includes patient-oriented communication tailored to patients' individualized needs. Common methods used in studies to increase question-asking are prompt lists and coaching pre-consultations. However, our patients were encouraged to ask questions by the physician during their visit. We aimed to estimate the quantity, nature, and variation of their questions when they were invited to ask by their oncologist. During radiotherapy consultations from 2012 to 2016, patient's questions were deliberately elicited and physician-transcribed...
February 12, 2018: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29430207/distribution-of-endangered-italian-gudgeon-romanogobio-benacensis-cypriniformes-cyprinidae-gobioninae-with-remarks-on-distinguishing-morphological-characters
#4
Dušan Jelić, Mišel Jelić, Petar Žutinić, Ivana Šimunović, Primož Zupančič, Alexander M Naseka
Distribution data on many freshwater fish species in Croatia are scarce and species identifications are difficult, requiring further detailed studies. This paper presents a report of the Italian gudgeon Romanogobio benacensis from the Mirna River in the Istra Peninsula in Croatia, in the south-east from its previously known distribution range. The identification of R. benacensis in Croatia was supported by a morphological comparison with R. benacensis from Italy and Slovenia, the common gudgeon Gobio gobio, and the Danubian gudgeon Gobio obtusirostris from geographically close locations...
2018: ZooKeys
https://www.readbyqxmd.com/read/29429130/ultrastructure-of-the-larval-malpighian-tubules-in-terrobittacus-implicatus-mecoptera-bittacidae
#5
Lu Liu, Bao-Zhen Hua
The larvae of Bittacidae, a cosmopolitan family in Mecoptera, have an interesting habit of spraying the body surface with soil through the anus after hatching, and each molts. The fine structure of Malpighian tubules, however, remains largely unknown in the larvae of Bittacidae to date. Here, we studied the ultrastructure of the larval Malpighian tubules in the hangingfly Terrobittacus implicatus (Huang & Hua) using scanning and transmission electron microscopy. The larvae of T. implicatus have six elongate Malpighian tubules at the junction of the midgut and hindgut...
February 10, 2018: Protoplasma
https://www.readbyqxmd.com/read/29418090/s2k-leitlinie-hpv-assoziierte-l%C3%A3-sionen-der-%C3%A3-u%C3%A3-eren-genitalregion-und-des-anus-genitalwarzen-und-krebsvorstufen-der-vulva-des-penis-und-der-peri-und-intraanalen-haut-kurzfassung
#6
Gerd E Gross, Ricardo N Werner, Jürgen C Becker, Norbert H Brockmeyer, Stefan Esser, Monika Hampl, Sara Hommel, Johannes Jongen, Dominik S Mestel, Thomas Meyer, Karl U Petry, Andreas Plettenberg, Klaus Püschel, Peter Schneede, Helmut Schöfer, Karl Sotlar, Gerhard Weyandt, Ulrike Wieland, Miriam Wiese-Posselt, Alexander Nast
No abstract text is available yet for this article.
February 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29418083/s2k-guideline-hpv-associated-lesions-of-the-external-genital-region-and-the-anus-anogenital-warts-and-precancerous-lesions-of-the-vulva-the-penis-and-the-peri-and-intra-anal-skin-short-version
#7
Gerd E Gross, Ricardo N Werner, Jürgen C Becker, Norbert H Brockmeyer, Stefan Esser, Monika Hampl, Sara Hommel, Johannes Jongen, Dominik S Mestel, Thomas Meyer, Karl U Petry, Andreas Plettenberg, Klaus Püschel, Peter Schneede, Helmut Schöfer, Karl Sotlar, Gerhard Weyandt, Ulrike Wieland, Miriam Wiese-Posselt, Alexander Nast
No abstract text is available yet for this article.
February 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29416670/genomic-landscape-of-colitis-associated-cancer-indicates-the-impact-of-chronic-inflammation-and-its-stratification-by-mutations-in-the-wnt-signaling
#8
Masashi Fujita, Nagahide Matsubara, Ikuo Matsuda, Kazuhiro Maejima, Ayako Oosawa, Tomoki Yamano, Akihiro Fujimoto, Mayuko Furuta, Kaoru Nakano, Aya Oku-Sasaki, Hiroko Tanaka, Yuichi Shiraishi, Raúl Nicolás Mateos, Kenta Nakai, Satoru Miyano, Naohiro Tomita, Seiichi Hirota, Hiroki Ikeuchi, Hidewaki Nakagawa
Inflammatory bowel disease (IBD) increases the risk of colorectal cancer, known as colitis-associated cancer (CAC). It is still unclear what driver mutations are caused by chronic inflammation and lead to CAC development. To get insight into this issue, we investigated somatic alterations in CAC. We performed exome sequencing of 22 fresh CACs and targeted sequencing of 43 genes on 90 archive specimens from Japanese CAC patients, of which 58 were ulcerative colitis (UC) and 32 were Crohn's disease (CD). Consistently with the previous reports, TP53 was commonly mutated (66%) whereas APC, KRAS and SMAD4 were mutated less frequently (16%, 11% and 11%, respectively)...
January 2, 2018: Oncotarget
https://www.readbyqxmd.com/read/29416290/omphalocele-exstrophy-of-cloaca-imperforate-anus-and-spinal-defect-complex-multiple-major-reconstructive-surgeries-needed
#9
Nada Neel, Mohmoud Salem Tarabay
OEIS complex is a rare combination of serious birth defects including omphalocele, exstrophy of cloaca, imperforate anus, and spinal defects. The aim of managements has shifted from merely providing survival to improve patient outcomes and quality of life with higher level of physical and social independence. Multiple complicated reconstructive surgeries always needed for achieving the goals of treatment. In this case report, we aimed to present our surgical approach for this rare abnormality to achieve functionally and socially acceptable outcome...
January 2018: Urology Annals
https://www.readbyqxmd.com/read/29413438/early-development-of-the-enteric-nervous-system-visualized-by-using-a-new-transgenic-zebrafish-line-harboring-a-regulatory-region-for-choline-acetyltransferase-a-chata-gene
#10
Masataka Nikaido, Saki Izumi, Honoka Ohnuki, Yuki Takigawa, Kyo Yamasu, Kohei Hatta
The enteric nervous system (ENS) is the largest part of the peripheral nervous system in vertebrates. Toward the visualization of the development of the vertebrate ENS, we report our creation of a new transgenic line, Tg(chata:GGFF2) which has a 1.5-kb upstream region of the zebrafish choline acetyltransferase a (chata) gene followed by modified green fluorescent protein (gfp). During development, GFP + cells were detected in the gut by 60 h post-fertilization (hpf). In the gut of 6- and 12-days post-fertilization (dpf) larvae, an average of 92% of the GFP + cells were positive for the neuronal marker HuC/D, suggesting that GFP marks enteric neurons in this transgenic line...
February 2, 2018: Gene Expression Patterns: GEP
https://www.readbyqxmd.com/read/29402589/dysomma-alticorpus-a-new-species-of-cutthroat-eel-from-the-gulf-of-aqaba-red-sea-teleostei-synaphobranchidae
#11
Ronald Fricke, Daniel Golani, Brenda Appelbaum-Golani, Uwe Zajonz
The cutthroat eel Dysomma alticorpus n. sp. is described based on a single specimen collected in a trammel net at a depth of 350m off Eilat, Israel, Gulf of Aqaba, Red Sea. The new species belongs to the Dysomma anguillare species complex, which comprises species possessing a well-developed pectoral fin, intermaxillary teeth, a uniserial row of 7-15 large compound teeth in the lower jaw (which may be followed by a few smaller teeth), and an anteriorly situated anus with the trunk shorter than the head length...
February 2, 2018: Comptes Rendus Biologies
https://www.readbyqxmd.com/read/29394624/-a-case-report-of-adenocarcinoma-with-pagetoid-growth-secondary-paget-s-disease-of-the-anal-canal
#12
Wataru Okajima, Yoshiaki Kuriu, Tomohiro Arita, Yasutoshi Murayama, Masayoshi Nakanishi, Tokunari Okayama, Toshiyuki Kosuga, Hirotaka Konishi, Ryo Morimura, Atsushi Shiozaki, Hisashi Ikoma, Takeshi Kubota, Hitoshi Fujiwara, Kazuma Okamoto, Eigo Otsuji
Differentiating primary Paget's disease from secondary Paget's disease, which is also known as Pagetoid growth of other cancers, in the perianal region is difficult. Given that the treatment strategies of both disease are significantly different, diagnosis of such conditions should be performed with caution. We report a case of secondary Paget's disease. A 76-year-old man previously visited a hospital because of erythematous plaque around the anus. It was diagnosed as extramammary Paget's disease based on skin biopsy results; consequently, perianal skin resection was performed...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29393494/depletion-of-aquaporin-1-decreased-adamts%C3%A2-4-expression-in-human-chondrocytes
#13
Masahiko Haneda, Shinya Hayashi, Tomoyuki Matsumoto, Shingo Hashimoto, Koji Takayama, Nobuaki Chinzei, Shinsuke Kihara, Kazuhiro Takeuchi, Kotaro Nishida, Ryosuke Kuroda
Inflammation serves an important role in the progression of osteoarthritis (OA), and IL‑1β may act as a catabolic factor on cartilage, reducing the synthesis of primary cartilage components type II collagen and aggrecan. Aquaporin 1 (AQP1) is a 28‑kDa water channel formed of six transmembrane domains on the cell membrane. AQP1 is highly expressed in the anus, gallbladder and liver, and is moderately expressed in the hippocampus, ependymal cells of the central nervous system and articular cartilage. It was hypothesized that AQP1 may be highly expressed in OA cartilage and that it may increase the expression of catabolic factors during inflammatory OA progression...
February 2, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29388672/use-of-the-purple-line-to-diagnose-cervical-dilatation-and-fetal-head-station-during-labor
#14
Rodrigo D Nunes, Paula Locatelli, Jefferson Traebert
The purple line is a red-purple spot that appears around the anus during labor in parallel with progression of cervical dilatation [1]. Its physiology is not well established and its appearance and growth during labor has been reported to be related to pelvic vascular congestion [2, 3]. The aim of the present study was to estimate the incidence of the purple line and if it can supplement the evaluation of labor progression. This article is protected by copyright. All rights reserved.
February 1, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29379239/a-rare-case-of-oeis-complex-newer-approach-to-diagnosis-of-exstrophy-bladder-by-color-doppler-and-its-differentiation-from-simple-omphalocele
#15
Kavita Aneja
The objective of this article is to present a new approach to diagnose and differentiate similar ventral masses by color Doppler. Two cases of ventral masses, a rare case of OEIS complex (Omphalocele-exstrophy-imperforate anus-spinal defects) with unusual presentation of exstrophy bladder and another of simple omphalocele, were studied by color Doppler for diagnosis and differentiation between the nature of similar masses. Ventral mass with absent bladder, normal kidneys, and normal amniotic fluid index raised the suspicion of exstrophy bladder...
October 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29372693/small-bowel-transanal-evisceration-mimicking-a-rectal-prolapse-a-case-report-and-review-of-literature
#16
Giuseppe Pisano, Enrico Erdas, Fabio Medas, Umberto Pisano, Pietro Giorgio Calò
Transanal intestinal evisceration is a very uncommon and dramatic occurrence, linked most frequently to rectal prolapse rupture or, very rarely, to traumatic pathology. The Authors describe a case of a 74-year-old female patient who required urgent hospital admission because of a seemingly strangulated rectal prolapse. During surgical preparation the protruding mass was recognized as small bowel loops herniating from the anus. Evisceration was due to spontaneous rectal wall rupture, most likely caused by increased abdominal pressure and consequent breach through the weakened rectum...
November 20, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29372108/complete-pathologic-response-after-chemoradiotherapy-in-a-patient-with-rectal-squamous-cell-carcinoma-a-case-report
#17
Zaied Sonia, Daldoul Amira, Bhiri Hanene, Ammar Nouha, Khechine Wiem, Toumi Omar, Abbes Ibtissem, Ben Salem Amina, Njima Manel, Mhabrech Houda
Squamous cell carcinoma (SCC) of the rectum is a rare disease. A 59-year-old man presented with SCC of the middle rectum located 10 cm from the anus. The stage of the tumor was revealed to be T3N+M0. The patient received a combined treatment with cisplatin and fluorouracil in concomitance with external radiation therapy. He then underwent an anterior resection of the rectum. The postoperative histopathological findings classified the tumor as ypT0N0 with cancer-free margins and lymph nodes. Treatment of SCC remains very challenging, and the acquisition of more consistent data is needed...
November 2017: Cancer Biology & Medicine
https://www.readbyqxmd.com/read/29370894/continence-after-posterior-sagittal-anorectoplasty-for-anorectal-malformations-comparison-of-different-scores
#18
Giulia Brisighelli, Francesco Macchini, Dario Consonni, Antonio Di Cesare, Anna Morandi, Ernesto Leva
PURPOSE: To evaluate bowel function in patients with anorectal malformations (ARM) comparing existing scoring systems. METHODS: Parents of ARM patients treated at our institution were asked to fill in Holschneider, Kricknebeck, and Rintala questionnaires. Scores obtained from the questionnaires were expressed per cent and analyzed depending on the age and type of ARM according to Krickenbeck classification. Patients younger than 3 years of age or with developmental delay were excluded...
December 27, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29363525/hybrid-capture-based-genomic-profiling-of-circulating-tumor-dna-from-patients-with-advanced-cancers-of-the-gastrointestinal-tract-or-anus
#19
Alexa B Schrock, Dean C Pavlick, Samuel J Klempner, Jon H Chung, Brady Forcier, Allison Welsh, Lauren Young, Brian Leyland-Jones, Rodolfo Bordonii, Richard D Carvajal, Joseph Chao, Razelle Kurzrock, Jason K Sicklick, Jeffrey S Ross, Philip J Stephens, Craig E Devoe, Fadi Braiteh, Siraj M Ali, Vincent Miller
PURPOSE: Genomic profiling of tumor biopsies from advanced gastrointestinal (GI) and anal cancers is increasingly used to inform treatment. In some cases, tissue biopsy can be prohibitive, and we sought to investigate whether analysis of blood-derived circulating tumor DNA (ctDNA) may provide a minimally invasive alternative. EXPERIMENTAL DESIGN: Hybrid capture-based genomic profiling of 62 genes was performed on blood-based ctDNA from 417 patients with GI carcinomas to assess the presence of genomic alterations (GA) and compare with matched tissue samples...
January 23, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29362337/-a-case-of-metastatic-carcinoma-of-anal-fistula
#20
Atsuo Imagawa, Satoshi Okumura, Sho Toyoda, Hiroshi Kawashima, Hiroshi Yasuda, Kansuke Yamamoto, Aya Ito, Naoto Mizumura, Ken Yoo, Hiromitsu Maehira, Masao Ogawa, Masayasu Kawasaki, Masao Kameyama, Genichiro Yoneda
A 58-year-old man underwent rectal resection(D2 dissection)for rectal cancer and liver/lung metastases in August 2009. Histopathological findings were Ra, type 2, 70×80mm, tub1>tub2, int, pSI(peritoneum), INF b, ly1, v1, pN1(2/13), pPM0, pDM0, M1a(H1, PUL1), fStage IV . The lung metastasis had disappeared on chest CT after postoperative chemotherapy and we were able to perform radical resection of the liver metastasis by performing hepatectomy twice. In October 2013, anal pain appeared and a painful tumor approximately 2 cm in size was found in the 5 o'clock direction of the anus...
January 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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