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https://www.readbyqxmd.com/read/27921449/reduction-mammaplasty-with-the-modified-round-block-technique-in-chinese-patients-and-its-anatomy-study
#1
Wei Ding, Yinjia Ding, Hua Jiang
BACKGROUND: Although reduction mammaplasty is one of the most common procedures in plastic surgery, it is associated with some serious complications, especially in cases of severe hypertrophy or advanced ptosis, including necrosis of the nipple and areola, absence of normal sensation of the nipple-areolar complex, and loss of lactational function for future nursing. A thorough understanding of the breast anatomy is vital for successful reduction mammaplasty. This article describes the blood supply and innervation of the breasts, and introduces a modified round block technique for reduction mammaplasty based on this anatomy...
December 6, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27920984/staphylococcus-lugdunensis-endocarditis-with-destruction-of-the-ventricular-septum-and-multiple-native-valves
#2
Celestine Ishiekwene, Monica Ghitan, Margaret Kuhn-Basti, Edward Chapnick, Yu Shia Lin
Staphylococcus lugdunensis (S. lugdunensis) is a coagulase negative staphylococcus (CoNS) that can cause destructive infective endocarditis. S. lugdunensis, unlike other CoNS, should be considered to be a pathogen. We report the first case of S. lugdunensis endocarditis causing ventricular septal defect and destruction of the aortic and mitral valves. A 53-year-old male with morbid obesity and COPD presented with intermittent fever and progressive shortness of breath for 2 weeks. Chest examination showed bilateral basal crepitations, and a grade 2 systolic murmur along the right sternal border...
2017: IDCases
https://www.readbyqxmd.com/read/27920666/circuits-regulating-pleasure-and-happiness-the-evolution-of-the-amygdalar-hippocampal-habenular-connectivity-in-vertebrates
#3
Anton J M Loonen, Svetlana A Ivanova
Appetitive-searching (reward-seeking) and distress-avoiding (misery-fleeing) behavior are essential for all free moving animals to stay alive and to have offspring. Therefore, even the oldest ocean-dwelling animal creatures, living about 560 million years ago and human ancestors, must have been capable of generating these behaviors. The current article describes the evolution of the forebrain with special reference to the development of the misery-fleeing system. Although, the earliest vertebrate ancestor already possessed a dorsal pallium, which corresponds to the human neocortex, the structure and function of the neocortex was acquired quite recently within the mammalian evolutionary line...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27919159/atrial-conduction-times-and-left-atrial-mechanical-functions-and-their-relation-with-diastolic-function-in-prediabetic-patients
#4
Naile Eris Gudul, Turgut Karabag, Muhammet Rasit Sayin, Taner Bayraktaroglu, Mustafa Aydin
Background/Aims: The aim of this study was to investigate atrial conduction times and left atrial mechanical functions, the noninvasive predictors of atrial fibrillation, in prediabetic patients with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). Methods: Study included 59 patients (23 males, 36 females; mean age 52.5 ± 10.6 years) diagnosed with IFG or IGT by the American Diabetes Association criteria, and 43 healthy adults (22 males, 21 females; mean age 48...
December 6, 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27908646/left-ventricular-function-in-healthy-term-neonates-during-the-transitional-period
#5
Amish Jain, Afif F El-Khuffash, Bart C W Kuipers, Adel Mohamed, Kim A Connelly, Patrick J McNamara, Robert P Jankov, Luc Mertens
OBJECTIVES: To evaluate whether incorporating conventional, tissue Doppler imaging and speckle tracking echocardiography are reliable and can characterize changes in left ventricular (LV) function properly in healthy neonates in the early transitional newborn period. STUDY DESIGN: A prospective observational study was conducted in 50 healthy term neonates with a mean ± SD gestational age and birth weight of 39.3 ± 1.2 weeks and 3.5 ± 0.44 kg, respectively...
November 28, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27905023/distinct-cortical-and-sub-cortical-neurogenic-domains-for-gabaergic-interneuron-precursor-transcription-factors-nkx2-1-olig2-and-coup-tfii-in-early-fetal-human-telencephalon
#6
Ayman Alzu'bi, Susan Lindsay, Janet Kerwin, Shi Jie Looi, Fareha Khalil, Gavin J Clowry
The extent of similarities and differences between cortical GABAergic interneuron generation in rodent and primate telencephalon remains contentious. We examined expression of three interneuron precursor transcription factors, alongside other markers, using immunohistochemistry on 8-12 post-conceptional weeks (PCW) human telencephalon sections. NKX2.1, OLIG2, and COUP-TFII expression occupied distinct (although overlapping) neurogenic domains which extended into the cortex and revealed three CGE compartments: lateral, medial, and ventral...
November 30, 2016: Brain Structure & Function
https://www.readbyqxmd.com/read/27895565/challenges-to-the-pair-bond-neural-and-hormonal-effects-of-separation-and-reunion-in-a-monogamous-primate
#7
Katie Hinde, Chelsea Muth, Nicole Maninger, Benjamin J Ragen, Rebecca H Larke, Michael R Jarcho, Sally P Mendoza, William A Mason, Emilio Ferrer, Simon R Cherry, Marina L Fisher-Phelps, Karen L Bales
Social monogamy at its most basic is a group structure in which two adults form a unit and share a territory. However, many socially monogamous pairs display attachment relationships known as pair bonds, in which there is a mutual preference for the partner and distress upon separation. The neural and hormonal basis of this response to separation from the adult pair mate is under-studied. In this project, we examined this response in male titi monkeys (Callicebus cupreus), a socially monogamous New World primate...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27893636/facial-contouring-by-targeted-restoration-of-facial-fat-compartment-volume-the-mid-face
#8
Wenjin Wang, Yun Xie, Ru-Lin Huang, Jia Zhou, Herrler Tanja, Peijuan Zhao, Chen Cheng, Sizheng Zhou, Lee L Q Pu, Qingfeng Li
BACKGROUND: Recent anatomical findings have suggested that facial fat distribution is complex and changes with age. Here, we developed a grafting technique based on the physiological distribution and volume changes of facial fat compartments to achieve a youthful and natural-looking face. METHODS: Forty cadaveric hemifaces were used for the dissection of fat compartments and neurovascular structures in the mid-face area. Seventy-eight patients were treated for cheek atrophy using our targeted restoration of mid-face fat compartment volume...
November 21, 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27891269/unruptured-basilar-tip-aneurysm-with-internal-septation-coiling-implications
#9
Ayman Khalil, Hong Kuan Kok, Mark Schembri, Paul Brennan, Mohsen Javadpour, John Thornton, Alan O'Hare, Hamed Asadi
An internal septum within a basilar artery aneurysm is an infrequent anomaly and is very rarely reported in the literature. We report a 62-year-old lady that was incidentally diagnosed with basilar tip aneurysm. Further imaging with magnetic resonance imaging (MRI) revealed internal septation within this aneurysm which was later confirmed with digital subtraction angiography (DSA). She underwent coil embolisation, which involved technical manipulation of the microcatheter and the balloon to enable coiling of each separate aneurysm compartment...
2016: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/27881171/assessment-of-left-atrial-mechanical-functions-and-atrial-electromechanical-delay-in-juvenile-idiopathic-arthritis-by-tissue-doppler-echocardiography
#10
Azza Z El Eraky, Nesrin M Handoka, Mona Sayed Ghaly, Samah Ismail Nasef, Nahed A Eldahshan, Ahmed M Ibrahim, Sherein Shalaby
BACKGROUND: Juvenile idiopathic arthritis (JIA) is a systemic chronic inflammatory disease. Studies using tissue Doppler imaging (TDI) for the evaluation of cardiac functions of children with JIA are limited. Thus, this study was conducted to evaluate Left ventricular function, left atrial mechanical functions and atrial electromechanical delay in JIA. METHODS: This study was carried out as a across sectional study. A total of 34 patients with active JIA and 34 controls were included...
November 24, 2016: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/27873373/cardiac-output-and-blood-flow-redistribution-in-the-fetus-with-d-loop-transposition-of-the-great-arteries-and-intact-ventricular-septum-insights-into-the-pathophysiology
#11
Max E Godfrey, Kevin G Friedman, Monika Drogosz, Abraham M Rudolph, Wayne Tworetzky
OBJECTIVES: Although the postnatal physiology of D-loop transposition of the great arteries with intact ventricular septum (DTGA-IVS) is well established, little is known about fetal DTGA-IVS. In the normal fetus, the pulmonary valve (PV) is larger than the aortic valve (AoV), there is exclusive right to left flow at the foramen ovale (FO) and ductus arteriosus (DA), and the left ventricle (LV) ejects 40% of combined ventricular output (CVO) through the aorta, primarily to the brain. In DTGA-IVS, the LV ejects O2 -rich blood to the pulmonary artery, theoretically leading to pulmonary vasodilation, increased branch pulmonary arterial flow and reduced DA flow...
November 22, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27872183/roles-of-the-essential-protein-ftsa-in-cell-growth-and-division-in-streptococcus-pneumoniae
#12
Andrea Mura, Daniela Fadda, Amilcar J Perez, Madeline L Danforth, Daniela Musu, Ana Isabel Rico, Marcin Krupka, Dalia Denapaite, Ho-Ching T Tsui, Malcolm E Winkler, Pavel Branny, Miguel Vicente, William Margolin, Orietta Massidda
: Streptococcus pneumoniae is an ovoid-shaped Gram-positive bacterium that grows by carrying out peripheral and septal peptidoglycan (PG) synthesis, analogous to model bacilli such as Escherichia coli and Bacillus subtilis In the model bacilli, FtsZ and FtsA proteins assemble into a ring at midcell and are dedicated to septal PG synthesis, but not peripheral PG synthesis; hence inactivation of FtsZ or FtsA results in long filamentous cells unable to divide. Here we demonstrate that FtsA and FtsZ colocalize at midcell in S...
November 21, 2016: Journal of Bacteriology
https://www.readbyqxmd.com/read/27870352/membranous-support-for-eyes-of-strepsirrhine-primates-and-fruit-bats
#13
Brianna M Harvey, Kunwar P Bhatnagar, Robert J Schenck, Alfred L Rosenberger, Susan J Rehorek, Anne M Burrows, Valerie B DeLeon, Timothy D Smith
Living primates have relatively large eyes and support orbital tissues with a postorbital bar (POB) and/or septum. Some mammals with large eyes lack a POB, and presumably rely on soft tissues. Here, we examined the orbits of four species of strepsirrhine primates (Galagidae, Cheirogaleidae) and three species of fruit bats (Pteropodidae). Microdissection and light microscopy were employed to identify support structures of the orbit. In bats and primates, there are two layers of fascial sheets that border the eye laterally...
December 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/27862708/the-role-of-ca3-ls-vta-loop-in-the-formation-of-conditioned-place-preference-induced-by-context-associated-reward-memory-for-morphine
#14
Jin-Xiang Jiang, Huan Liu, Zhen-Zhen Huang, Yue Cui, Xue-Qin Zhang, Xiao-Long Zhang, Yu Cui, Wen-Jun Xin
Addiction-related behaviors, such as conditioned place preference (CPP), require animals to remember an association between environmental cue and drug treatment, and exposure to environmental cue is one of the key contributing factors to relapse. However, how central neural circuit participates in the formation of CPP induced by stimulus of morphine-paired environment remains unknown. In the present study, we found that reexposure to morphine-paired environment significantly increased the activity of hippocampal CA3 neurons, increased the excitability of GABAergic neurons and expression of glutamic acid decarboxylase 65/67 in the caudal lateral septum (LSc) and decreased the activity of GABAergic neurons and GAD65/67 expression in ventral tegmental area (VTA), leading to activation (disinhibition) of dopaminergic neurons...
November 11, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27859793/selective-contribution-of-the-telencephalic-arcopallium-to-the-social-facilitation-of-foraging-efforts-in-the-domestic-chick
#15
Qiuhong Xin, Yukiko Ogura, Leo Uno, Toshiya Matsushima
To investigate the neural basis of socio-economic behaviors in birds, we examined the effects of bilateral electrolytic lesions of arcopallium (Arco, the major descending pallial area of the avian telencephalon) and the surrounding nuclei in domestic chicks. We tested foraging effort (running distance) in an I-shaped maze with two food patches that delivered food in a biased manner according to a variable interval schedule. Normally, chicks run back and forth between the patches, and the patch use time matches the respective food delivery rate...
November 12, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27857874/minimizing-septectomy-for-endoscopic-transsphenoidal-approaches-to-the-sellar-and-suprasellar-regions-a-cadaveric-morphometric-study
#16
Hermes G Garcia, Marc Otten, Marc Pyfer, Saurabh J Singhal, Alfred Marc Iloreta, Varun R Kshettry, Christopher J Farrell, Gurston Nyquist, Marc Rosen, James J Evans
The purpose of this study was to evaluate the effect of posterior septectomy size on surgical exposure and surgical freedom during the endoscopic transsphenoidal approach to the sella and parasellar region. Dissections were performed on 10 embalmed cadaver heads. Dissections started with wide bilateral sphenoidotomies, lateralization of middle turbinates, and a 5-mm posterior septectomy. The posterior septectomy was increased in 5-mm increments to a maximum of 35 mm, followed by bilateral middle turbinectomies...
December 2016: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/27852437/cell-wall-remodeling-drives-engulfment-during-bacillus-subtilis-sporulation
#17
Nikola Ojkic, Javier López-Garrido, Kit Pogliano, Robert G Endres
When starved, the Gram-positive bacterium Bacillus subtilis forms durable spores for survival. Sporulation initiates with an asymmetric cell division, creating a large mother cell and a small forespore. Subsequently, the mother cell membrane engulfs the forespore in a phagocytosis-like process. However, the force generation mechanism for forward membrane movement remains unknown. Here, we show that membrane migration is driven by cell wall remodeling at the leading edge of the engulfing membrane, with peptidoglycan synthesis and degradation mediated by penicillin binding proteins in the forespore and a cell wall degradation protein complex in the mother cell...
November 17, 2016: ELife
https://www.readbyqxmd.com/read/27847734/surgical-implications-of-anatomical-variation-in-anterolateral-thigh-flaps-for-the-reconstruction-of-oral-and-maxillofacial-soft-tissue-defects-focus-on-perforators-and-pedicles
#18
Ji-Wan Kim, Dong-Young Kim, Kang-Min Ahn, Jee-Ho Lee
OBJECTIVES: To gain information on anatomical variation in anterolateral thigh (ALT) flaps in a series of clinical cases, with special focus on perforators and pedicles, for potential use in reconstruction of oral and maxillofacial soft tissue defects. MATERIALS AND METHODS: Eight patients who underwent microvascular reconstructive surgery with ALT free flaps after ablative surgery for oral cancer were included. The number of perforators included in cutaneous flaps, location of perforators (septocutaneous or musculocutaneous), and the course of vascular pedicles were intraoperatively investigated...
October 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/27847560/left-ventricular-false-tendons-and-electrocardiogram-repolarization-abnormalities-in-healthy-young-subjects
#19
Zlatan Lazarevic, Emanuela Ciminelli, Federico Quaranta, Fabio Sperandii, Emanuele Guerra, Fabio Pigozzi, Paolo Borrione
AIM: To describe echocardiographically left ventricular false tendon characteristics and the correlation with ventricular repolarization abnormalities in young athletes. METHODS: Three hundred and sixteen healthy young athletes from different sport disciplines were evaluated from 2009 to 2011 during routine screening for agonistic sports eligibility. All subjects, as part of standard pre-participation screening medical evaluation, underwent a basal and post step test 12-lead electrocardiogram (ECG)...
October 26, 2016: World Journal of Cardiology
https://www.readbyqxmd.com/read/27847478/the-protective-effects-of-ivabradine-in-preventing-progression-from-viral-myocarditis-to-dilated-cardiomyopathy
#20
Li Yue-Chun, Chen Guang-Yi, Ge Li-Sha, Xing Chao, Tian Xinqiao, Lin Cong, Dai Xiao-Ya, Yang Xiangjun
To study the beneficial effects of ivabradine in dilated cardiomyopathy (DCM) mice, which evolved from coxsackievirus B3-induced chronic viral myocarditis. Four-to-five-week-old male balb/c mice were inoculated intraperitoneally with coxsackievirus B3 (Strain Nancy) on days 1, 14, and 28. The day of the first virus inoculation was defined as day 1. Thirty-five days later, the surviving chronic viral myocarditis mice were divided randomly into two groups, a treatment group and an untreated group. Ivabradine was administered by gavage for 30 consecutive days in the treatment group, and the untreated group was administered normal saline...
2016: Frontiers in Pharmacology
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