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https://www.readbyqxmd.com/read/29161694/immunohistochemical-localization-of-darpp-32-in-the-brain-of-two-lungfishes-further-assessment-of-its-relationship-with-the-dopaminergic-system
#1
Jesús M López, Ruth Morona, Agustín González
The distribution of DARPP-32 (a phosphoprotein related to the dopamine D1 receptor) has been widely used as a means to clarify the brain regions with dopaminoceptive cells, primarily in representative species of tetrapods. The relationship between dopaminergic and dopaminoceptive elements is frequently analyzed using the catecholamine marker tyrosine hydroxylase (TH). In the present study, by means of combined immunohistochemistry, we have analyzed these relationships in lungfishes, the only group of sarcopterygian fishes represented by 6 extant species that are the phylogenetically closest living relatives of tetrapods...
November 22, 2017: Brain, Behavior and Evolution
https://www.readbyqxmd.com/read/29151411/-protective-effect-of-thalidomide-on-ali-induced-by-paraquat-poisoning-in-rats-and-its-mechanism
#2
Tao Liu, Yuan Xie, Mengtong Xu, Fenshuang Zheng
OBJECTIVE: To investigate the protective effect of thalidomide on acute lung injury (ALI) induced by paraquat (PQ) poisoning in rats and its possible mechanism. METHODS: Sixty SPF Wistar rats were randomly divided into six groups with 10 rats in each group. The rat model of PQ poisoning was reproduced by intraperitoneal injection of PQ solution 20 mg/kg (PQ model group), and the rats were treated by intraperitoneal injection of gradient thalidomide (50, 100, 200 mg/kg treatment groups) 30 minutes later continuously for 3 days...
November 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29146391/small-diameter-hysteroscopic-metroplasty-for-a-septate-uterus-after-open-assisted-laparoscopic-radical-trachelectomy
#3
Akimasa Takahashi, Hiroyuki Kanao, Nobuhiro Takeshima
STUDY OBJECTIVE: To describe a two-step fertility preservation technique for early-stage cervical cancer of a patient with a complete septate uterus. DESIGN: A step-by-step demonstration and explanation of the technique in a surgical video (Canadian Task Force Classification III). SETTING: Center for cancer, a tertiary referral center. The patient provided informed consent to use images and videos of the procedure. Institutional Review Board approval was not required for this kind of procedure...
November 13, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29135290/-study-of-the-canalis-mandibulae-morphology-in-different-vertical-facial-types
#4
Krisztina Mártha I, Cristina Bica, Blanka Kész, Bernadette Kerekes Máthé
INTRODUCTION: The precise knowledge of the position of canalis mandibulae and foramen mandibulae is important for surgical and endodontic interventions on the mandible. AIM: The aim of the study is to examine the position of these anatomical landmarks in different vertical facial types. METHOD: In the panorama radiograph of 26 normodivergent, 26 hypodivergent and 28 hyperdivergent arthritis (total of 1360 measurements) we measured the distance between the canalis mandibulae and interdental septums, the apex of the lateral teeth, the mandibular base, the goniac angle, and the steepness of the canal and the distance the foramen mandibulae to the anterior and posterior margin of the ramus...
November 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29133151/laparoscopic-management-of-a-rudimentary-uterine-horn
#5
Emilie Faller, Jean Jacques Baldauf, François Becmeur, Anne Lehn, Cherif Youssef Akladios, Lise Lecointre
STUDY OBJECTIVE: To demonstrate a technique of laparoscopic management of a rudimentary horn in a 12-year-old girl. DESIGN: A step-by-step explanation of the surgery using video (instructive video), approved the local institutional Review Board. SETTING: A university hospital, University Hospital of Strasbourg, France. PATIENT: A 12-year-old girl with a uterine rudimentary horn. INTERVENTION: We describe the case of a 12 years old girl who had no medical history...
November 10, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29126760/nuances-in-component-nasal-hump-reduction
#6
Haneen Sadick, Julian M Rowe-Jones, Holger G Gassner
IMPORTANCE: Nasal hump reduction is a frequent manoeuvre in rhinoplasty. Over the last years, composite hump reduction has been advocated in favour of component hump reduction. The latter allows a more controlled and stepwise approach in reducing the nasal dorsum by deprojecting the cartilaginous dorsum separately from the bony dorsum. This approach also preserves the upper lateral cartilages (ULCs) and their mucosa. OBJECTIVE: To analyse the intricacies of the anatomic transition zone between the ULCs, the rhinion and the nasal bones as they pertain to component hump reduction...
October 20, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29124376/an-alternative-rhinoplasty-technique-rotational-spreader-flap-rabbit-flap
#7
Ali Ahmet Sirin, Ibrahim Erdim, Omer Erdur, Alperen Sirin
BACKGROUND: In modern rhinoplasty, septal cartilage is the most commonly used graft material. It is a big challenge if septal cartilage is insufficient. We present an alternative technique named the "rabbit flap," created from the cephalic portion of the lower lateral cartilage to show its effectiveness on nasolabial angle, nasal axis deviation, and nasal dorsal line. METHODS: An alternative flap, called a "rabbit flap," is constituted from the cephalic portion of the lower lateral cartilage (LLC)...
November 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29122676/a-six-gene-expression-toolbox-for-the-glands-epithelium-and-chondrocytes-in-the-mouse-nasal-cavity
#8
Yong Wan, Matthew B Rogers, Heather L Szabo-Rogers
The nose is the central feature of the amniote face. In adults, the nose is a structurally and functionally complex organ that consists of bone, cartilage, glands and ducts. In an ongoing expression screen in our lab, we found several novel markers for specific tissues in the nasal region. Here, using in situ hybridization expression experiments, we report that Alx1, Ap-2β, Crispld1, Eya4, Moxd1, and Penk have tissue specific expression during murine nasal development. At E11.5, we observed that Alx1, Ap-2β, Crispld1, and Eya4 are expressed in the medial and lateral nasal prominences...
November 6, 2017: Gene Expression Patterns: GEP
https://www.readbyqxmd.com/read/29122426/anatomical-factors-contributing-to-radial-nerve-excursion-at-the-brachium-a-cadaveric-study
#9
Wayne A Chen, T David Luo, Michael D Wigton, Zhongyu Li
PURPOSE: The radial nerve appears to be more vulnerable to injury in the brachium than the median and ulnar nerves. The underlying mechanism for this increased vulnerability is not well explained. We hypothesize that the radial nerve has less excursion than the median and ulnar nerves because it is anatomically tethered by the lateral intermuscular septum (LIS) and that elbow positioning and LIS release will improve its excursion. METHODS: Eight paired fresh-frozen cadaveric upper extremity specimens were used...
November 7, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29104201/-cardiac-perforation-after-pacemaker-implantation-report-of-a-case
#10
Yuko Ohashi, Kazuhiro Ohkura, Ayano Yamada
A 71-year-old woman was diagnosed with sick sinus syndrome (SSS) upon her cardiogenic cerebral embolism and underwent pacemaker implantation. Active fixation leads were positioned at the right atrial appendage and ventricular septum. Twenty-one days later at her routine checkup, she was asymptomatic and there were no signs of cardiac tamponade or pacing failure. But echocardiography and computed tomography revealed a large amount of pericardial effusion due to the lead perforation. We performed open drainage because her anticoagulant could not be stopped for her history of cerebral infarction...
November 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29100991/cue-induced-reinstatement-of-alcohol-seeking-behavior-is-associated-with-increased-camkii-t286-phosphorylation-in-the-reward-pathway-of-mice
#11
Michael C Salling, Christopher J Hodge, Kelly E Psilos, Vallari R Eastman, Sara P Faccidomo, Clyde W Hodge
Cue-induced reinstatement of alcohol-seeking is a hallmark behavioral pathology of addiction. Evidence suggests that reinstatement (e.g., relapse), may be regulated by cell signaling systems that underlie neuroplasticity. A variety of plasticity events require activation of calcium calmodulin-dependent protein kinase II (CaMKII) in components of the reward pathway, such as the nucleus accumbens and amygdala. We sought to determine if cue-induced reinstatement of alcohol-seeking behavior is associated with changes in the activation state (e...
October 31, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/29076284/right-ventricular-speckle-tracking-assessment-for-differentiation-of-pressure-versus-volume-overloaded-right-ventricle
#12
Anna Werther Evaldsson, Annika Ingvarsson, Johan Waktare, Gustav J Smith, Ulf Thilén, Martin Stagmo, Anders Roijer, Goran Rådegran, Carl Meurling
BACKGROUND: Right ventricular (RV) dysfunction may be caused by either pressure or volume overload. RV function is conventionally assessed with echocardiography using tricuspid annular plane systolic excursion (TAPSE), RV fractional area change (RVFAC), tricuspid lateral annular systolic velocity (S') and RV index of myocardial performance (RIMP). The purpose of this study was to evaluate whether RV global longitudinal strain (RVGLS) and RV-free wall strain (RV-free) could add additional information to differentiate these two causes of RV overload...
October 26, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29055081/a-new-endoscopic-technique-to-close-big-nasal-septal-perforations-prospective-evaluation-of-the-double-meat-hook-technique-in-19-consecutive-cases
#13
H Dixon, F R Datema
Despite the variety of surgical techniques available to close big symptomatic septum perforations, closure rates of 30 to 70% indicate the difficulty of obtaining a good end result. The double meat hook technique is a new endoscopically assisted technique that delivers excellent visualization and control of mucosal flap elevation, extension and suturing. Mucosa from the nasal floor, lateral nasal wall and inferior turbinate bone are valuable donor site extensions. There is no need for additional incisions into the nasal septal mucosa in order to perform a tension-free closure...
October 21, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29049070/noninfectious-fever-in-the-near-term-pregnant-rat-induces-fetal-brain-inflammation-a-model-for-the-consequences-of-epidural-associated-maternal-fever
#14
Scott Segal, Carlo Pancaro, Iwona Bonney, James E Marchand
BACKGROUND: Women laboring with epidural analgesia experience fever much more frequently than do women who chose other forms of analgesia, and maternal intrapartum fever is associated with numerous adverse consequences, including brain injury in the fetus. We developed a model of noninfectious inflammatory fever in the near-term pregnant rat to simulate the pathophysiology of epidural-associated fever and hypothesized that it would produce fetal brain inflammation. METHODS: Twenty-four pregnant Sprague-Dawley rats were studied at 20 days gestation (term: 22 days)...
October 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29044802/differential-and-complementary-roles-of-medial-and-lateral-septum-in-the-orchestration-of-limbic-oscillations-and-signal-integration
#15
Marian Tsanov
Anatomical differences between the medial and lateral septum have associated these nuclei with dissimilar functional roles and behaviors. While the medial septum has been implicated, predominantly, in theta rhythm generation along the septo-hippocampal axis, the lateral septum has mainly been investigated in the context of septo-hypothalamic dialogue. Recent advances suggest that medial and lateral septum are more closely functionally-related than previously appreciated. Here, we explore the hypothesis that the medial septum mediates ascending septo-hippocampal theta propagation, while the lateral septum processes a descending hippocampo-septal and septo-hypothalamic reinforcement signal that mediates navigation during motivated behavior...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29037912/early-emergence-of-altered-5-ht2a-receptor-evoked-behavior-neural-activation-and-gene-expression-following-maternal-separation
#16
Ankit Sood, Sthitapranjya Pati, Amrita Bhattacharya, Karina Chaudhari, Vidita A Vaidya
The early stress of Maternal Separation (MS) contributes to the establishment of adult psychopathology. The serotonergic (5-HT) system is implicated during this temporal window in mediating the development of mood-related behaviors. MS is reported to evoke altered 5-HT2A receptor function in adulthood. However, the ontogeny of altered 5-HT2A receptor responsivity following MS remains unknown. Here, we examined 5-HT2A receptor agonist, DOI (1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane) (2mg/kg) evoked responses, namely stereotypical head-twitch behaviors in control and MS Sprague-Dawley rat pups at postnatal day 21 (P21)...
October 14, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/29033082/root-canal-morphology-evaluation-of-central-and-lateral-mandibular-incisors-using-cone-beam-computed-tomography-in%C3%A2-an%C3%A2-israeli%C3%A2-population
#17
Avi Shemesh, Eitan Kavalerchik, Avi Levin, Joe Ben Itzhak, Oleg Levinson, Alex Lvovsky, Michael Solomonov
INTRODUCTION: Central and lateral mandibular incisors usually have 1 root canal. The purpose of this study was to investigate the prevalence of additional root canals in central and lateral mandibular incisors and to investigate the prevalence of oval and long oval canals in the cervical, middle, and apical thirds of cases with 1 root canal. METHODS: A total of 1016 Israeli patients' cone-beam computed tomography scans were screened and evaluated. A total of 1472 central mandibular incisors and 1508 lateral mandibular incisors were examined...
October 12, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29019612/unveiling-transthyretin-cardiac-amyloidosis-and-its-predictors-among-elderly-patients-with-severe-aortic-stenosis-undergoing-transcatheter-aortic-valve-replacement
#18
Adam Castaño, David L Narotsky, Nadira Hamid, Omar K Khalique, Rachelle Morgenstern, Albert DeLuca, Jonah Rubin, Codruta Chiuzan, Tamim Nazif, Torsten Vahl, Isaac George, Susheel Kodali, Martin B Leon, Rebecca Hahn, Sabahat Bokhari, Mathew S Maurer
Aims: Transthyretin cardiac amyloidosis (ATTR-CA) has been reported in patients with aortic stenosis (AS) but its prevalence and phenotype are not known. We examine elderly patients with severe symptomatic AS undergoing transcatheter aortic valve replacement (TAVR) and determine the prevalence and phenotype of ATTR-CA non-invasively. Methods and results: We performed technetium-99m pyrophosphate (99mTc-PYP) cardiac scintigraphy prospectively on patients who underwent TAVR, to screen for ATTR-CA...
October 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29018500/computed-tomography-measurement-of-inferior-turbinate-in-asymptomatic-adult
#19
Mohammad Waheed El-Anwar, Atef A Hamed, Ghada Abdulmonaem, Ismail Elnashar, Inas M Elfiki
Introduction  The inferior turbinate (IT) is the most susceptible turbinate to enlargement causing nasal obstruction. The common belief ascribes most of the enlargement of the IT to mucosal elements. Objective  This study aimed to investigate the detailed computed tomography (CT) measurement of the IT in asymptomatic adult by determining the thickness of both the non-bony (mucosa) and bony parts and their relation to nasal air space in different related areas of the nose. Methods  We included in the study paranasal CT scans of 108 individuals (216 IT) that had no paranasal pathology...
October 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29017464/respective-contribution-of-the-cephalic-neural-crest-and-mesoderm-to-six1-expressing-head-territories-in-the-avian-embryo
#20
Barbara F Fonseca, Gérard Couly, Elisabeth Dupin
BACKGROUND: Vertebrate head development depends on a series of interactions between many cell populations of distinct embryological origins. Cranial mesenchymal tissues have a dual embryonic source: - the neural crest (NC), which generates most of craniofacial skeleton, dermis, pericytes, fat cells, and tenocytes; and - the mesoderm, which yields muscles, blood vessel endothelia and some posterior cranial bones. The molecular players that orchestrate co-development of cephalic NC and mesodermal cells to properly construct the head of vertebrates remain poorly understood...
October 10, 2017: BMC Developmental Biology
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