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https://www.readbyqxmd.com/read/29051132/how-should-i-treat-a-rupture-of-the-interatrial-septum-with-haemodynamically-relevant-right-to-left-shunt-during-mitraclip-implantation
#1
Tobias Schmidt, Hannes Alessandrini, Felix Kreidel, Tobias Spangenberg, Michael Schlüter, Jochen Kannmacher, Ralf Bader, Thomas Thielsen, Karl-Heinz Kuck, Christian Frerker, Ivan P Casserly, Miles W H Behan, Anne Scott, Ajay Yerramasu, Alan Japp, Renzo Pessotto, David B Northridge
No abstract text is available yet for this article.
October 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29049834/percutaneous-left-atrial-unloading-to-prevent-pulmonary-oedema-and-to-facilitate-ventricular-recovery-under-extracorporeal-membrane-oxygenation-therapy
#2
Alexander M Bernhardt, Mathias Hillebrand, Yalin Yildirim, Samer Hakmi, Florian M Wagner, Stefan Blankenberg, Hermann Reichenspurner, Edith Lubos
OBJECTIVES: Left-sided unloading during extracorporeal membrane oxygenation (ECMO) therapy is crucial to prevent pulmonary oedema and facilitate ventricular recovery. We present the case of a 55-year-old man under ECMO therapy with pre-existing left ventricular (LV) thrombus formation and in need of ventricular unloading. METHODS: We implanted a 21-Fr TandemHeart Protek Solo trans-septal cannula into the left atrium using a trans-septal approach via the femoral vein...
September 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049818/dor-procedure-for-pulmonary-atresia-with-intact-ventricular-septum-in-an-infant
#3
Yoonjin Kang, Jae Gun Kwak, Eung Rae Kim, Woong-Han Kim
Pulmonary atresia with intact ventricular septum and right ventricle-dependent coronary circulation confers a high risk for myocardial infarction and complications of ischaemia, including left ventricle aneurysms. We describe an infant with pulmonary atresia with intact ventricular septum and right ventricle-dependent coronary circulation and a left ventricle apical aneurysm who successfully underwent the Dor procedure and a subsequent Fontan operation. Surgery for postinfarction left ventricle aneurysm can be considered in infants...
September 2, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049345/processing-of-the-major-autolysin-of-e-faecalis-atla-by-the-zinc-metalloprotease-gele-impacts-atla-septal-localization-and-cell-separation
#4
Emily K Stinemetz, Peng Gao, Kenneth L Pinkston, Maria Camila Montealegre, Barbara E Murray, Barrett R Harvey
AtlA is the major peptidoglycan hydrolase of Enterococcus faecalis involved in cell division and cellular autolysis. The secreted zinc metalloprotease, gelatinase (GelE), has been identified as an important regulator of cellular function through post-translational modification of protein substrates. AtlA is a known target of GelE, and their interplay has been proposed to regulate AtlA function. To study the protease-mediated post-translational modification of AtlA, monoclonal antibodies were developed as research tools...
2017: PloS One
https://www.readbyqxmd.com/read/29049170/case-report-of-a-congenital-duodenal-transverse-septum-causing-partial-obstruction
#5
Xingjun Guo, Yahong Yu, Min Wang, Renyi Qin
INTRODUCTION: Duodenal obstructions caused by congenital anatomic abnormalities are rare in adults. Several patients in whom the duodenal obstruction was caused by a congenital duodenal diaphragm have been described. The duodenal obstruction in the patient presented herein was caused by a transverse septum, which has not been previously reported. A transverse septum is usually observed in the vagina; those involving the digestive tract have been rarely observed. CASE PRESENTATION: We herein report a case involving a 69-year-old woman with a congenital duodenal transverse septum causing partial obstruction...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29049070/noninfectious-fever-in-the-near-term-pregnant-rat-induces-fetal-brain-inflammation-a-model-for-the-consequences-of-epidural-associated-maternal-fever
#6
Scott Segal, Carlo Pancaro, Iwona Bonney, James E Marchand
BACKGROUND: Women laboring with epidural analgesia experience fever much more frequently than do women who chose other forms of analgesia, and maternal intrapartum fever is associated with numerous adverse consequences, including brain injury in the fetus. We developed a model of noninfectious inflammatory fever in the near-term pregnant rat to simulate the pathophysiology of epidural-associated fever and hypothesized that it would produce fetal brain inflammation. METHODS: Twenty-four pregnant Sprague-Dawley rats were studied at 20 days gestation (term: 22 days)...
October 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29047321/perioperative-and-anesthetic-considerations-in-pulmonary-atresia-with-intact-ventricular-septum
#7
Stephen Gleich, Gregory J Latham, Denise Joffe, Faith J Ross
Pulmonary atresia with intact ventricular septum (PA/IVS) is a rare right-heart obstructive lesion with a wide anatomic and physiologic spectrum of disease, ranging from simple membranous pulmonary valve atresia with a fully developed right ventricle (RV) to a severely hypoplastic RV and ventriculocoronary (RV-coronary) fistulas. Affected neonates are dependent on prostaglandin for adequate pulmonary blood flow. Depending on the severity of disease, treatment options range from transcatheter pulmonary valve perforation and ultimate biventricular repair to staged single-ventricle palliation...
October 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29046888/imaging-sex-differences-in-regional-brain-metabolism-during-acute-opioid-withdrawal
#8
Giovanni C Santoro, Joseph Carrion, Stephen L Dewey
The rate of opioid overdose continues to rise, necessitating improved treatment options. Current therapeutic approaches rely on administration of either a blocking agent, such as naloxone, or chronic treatment with replacement drugs, including methadone and/or buprenorphine. Recent findings suggest that males and females respond to these treatments uniquely. In an effort to better understand this sex-specific variation in treatment efficacy, we investigated the effects of acute opioid withdrawal in male and female rats using 18FDG and microPET...
April 2017: Journal of Alcoholism and Drug Dependence
https://www.readbyqxmd.com/read/29044802/differential-and-complementary-roles-of-medial-and-lateral-septum-in-the-orchestration-of-limbic-oscillations-and-signal-integration
#9
Marian Tsanov
Anatomical differences between the medial and lateral septum have associated these nuclei with dissimilar functional roles and behaviors. While the medial septum has been implicated, predominantly, in theta rhythm generation along the septo-hippocampal axis, the lateral septum has mainly been investigated in the context of septo-hypothalamic dialogue. Recent advances suggest that medial and lateral septum are more closely functionally-related than previously appreciated. Here, we explore the hypothesis that the medial septum mediates ascending septo-hippocampal theta propagation, while the lateral septum processes a descending hippocampo-septal and septo-hypothalamic reinforcement signal that mediates navigation during motivated behavior...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29043534/male-produced-aggregation-pheromone-of-coffee-bean-weevil-araecerus-fasciculatus
#10
Shuai Yang, Xiao-Fang Zhang, Yu-Lin Gao, Dan Chen, Dong-Mei She, Tao Zhang, Jun Ning
The coffee bean weevil (CBW), Araecerus fasciculatus (De Geer, 1775), is a cosmopolitan stored-product pest, especially in tropical and subtropical areas. Previous reports showed evidence for aggregation behavior of CBW and this study aimed to identify and evaluate the aggregation pheromone of this pest. Whole-body solvent extractions were analyzed by coupled gas chromatography-mass spectrometry and comparison of male and female extracts showed a male-specific compound which was identified as squalene, 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene...
October 17, 2017: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/29037912/early-emergence-of-altered-5-ht2a-receptor-evoked-behavior-neural-activation-and-gene-expression-following-maternal-separation
#11
Ankit Sood, Sthitapranjya Pati, Amrita Bhattacharya, Karina Chaudhari, Vidita A Vaidya
The early stress of Maternal Separation (MS) contributes to the establishment of adult psychopathology. The serotonergic (5-HT) system is implicated during this temporal window in mediating the development of mood-related behaviors. MS is reported to evoke altered 5-HT2A receptor function in adulthood. However, the ontogeny of altered 5-HT2A receptor responsivity following MS remains unknown. Here, we examined 5-HT2A receptor agonist, DOI (1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane) (2mg/kg) evoked responses, namely stereotypical head-twitch behaviors in control and MS Sprague-Dawley rat pups at postnatal day 21 (P21)...
October 14, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/29035892/patent-foramen-ovale-as-possible-cause-of-sudden-sensorineural-hearing-loss-a-case-report
#12
Andrea Ciorba, Virginia Corazzi, Luca Cerritelli, Chiara Bianchini, Giovanni Scanelli, Claudia Aimoni
OBJECTIVE: To present a case of sudden sensorineural hearing loss (SSNHL) and the related diagnostic work-up. CLINICAL PRESENTATION AND INTERVENTION: A 54-year-old man presented with unilateral SSNHL episode and vertigo. A severe patent foramen ovale (PFO) that included a complete ear nose and throat, audiological and neurological examination was discovered during the diagnostic work-up. Audiometry, blood and serological tests were performed. Magnetic resonance imaging (MRI), supra-aortic trunks and lower limbs color Doppler echography were done...
October 16, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29035676/the-molecular-mechanism-and-neuroprotective-effect-of-dihydrocapsaicin-induced-mild-hypothermia-after-cardiopulmonary-resuscitation-in-rats
#13
Xiaopeng Zhong, Xiujuan Wang, Fei Fei, ManCui Zhang, Po Ding, Shiwu Zhang
To investigate the molecular mechanism of dihydrocapsaicin (DHC)-induced mild hypothermia in rats, and to compare its protective effect on the central nervous system with that of a conventional method of inducing hypothermia, 24 healthy male Sprague Dawley rats were randomly divided into four groups based on the following conditions: control group, cardiopulmonary resuscitation (CPR) group, body surface cooling group, and DHC group. Tracheal clipping was used to mimic asphyxia arrest. Rats were assessed for their neurological deficit scores...
October 16, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29033082/root-canal-morphology-evaluation-of-central-and-lateral-mandibular-incisors-using-cone-beam-computed-tomography-in%C3%A2-an%C3%A2-israeli%C3%A2-population
#14
Avi Shemesh, Eitan Kavalerchik, Avi Levin, Joe Ben Itzhak, Oleg Levinson, Alex Lvovsky, Michael Solomonov
INTRODUCTION: Central and lateral mandibular incisors usually have 1 root canal. The purpose of this study was to investigate the prevalence of additional root canals in central and lateral mandibular incisors and to investigate the prevalence of oval and long oval canals in the cervical, middle, and apical thirds of cases with 1 root canal. METHODS: A total of 1016 Israeli patients' cone-beam computed tomography scans were screened and evaluated. A total of 1472 central mandibular incisors and 1508 lateral mandibular incisors were examined...
October 12, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29032895/cardiac-sympathetic-denervation-predicts-pd-in-at-risk-individuals
#15
David S Goldstein, Courtney Holmes, Grisel J Lopez, Tianxia Wu, Yehonatan Sharabi
INTRODUCTION: By the time a person develops the motor manifestations of Parkinson's disease (PD), substantial loss of nigrostriatal dopamine neurons has already occurred. There is great interest in identifying biomarkers that can detect pre-clinical PD. Braak's neuropathological staging concept imputes early autonomic involvement. Here we report results from a small prospective cohort study about the utility of neuroimaging evidence of cardiac sympathetic denervation in predicting PD among individuals with multiple PD risk factors...
October 5, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29031221/effects-of-particulate-matter-from-straw-burning-on-lung-fibrosis-in-mice
#16
Yang Hu, Liu-Sheng Wang, Yan Li, Qiu-Hong Li, Chun-Lin Li, Jian-Min Chen, Dong Weng, Hui-Ping Li
OBJECTIVE: To investigate the impacts of particulate matter 2.5 (PM2.5) from straw burning on the acute exacerbation of lung fibrosis in mice and the preventive effects of N-acetylcysteine (NAC). METHODS: The composition, particle size, and 30-min concentration change in an exposure system of the PM2.5 from straw-burning were determined. Forty C57BL male mice were equally randomized to two groups: bleomycin (BLM)-induced lung fibrosis with an exposure to air (BLM+air) and BLM+PM2...
October 7, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29026816/aesthetic-refinements-in-forehead-flap-reconstruction-of-the-asian-nose
#17
Yen-Chang Hsiao, Chun-Shin Chang, Jonathan Zelken
BACKGROUND: Traditional paramedian forehead flap reconstruction exploits the aesthetic subunit principle. Refinements and outcomes of forehead flap nasal reconstruction largely reflect Western experience. Differences in ethnic Asian anatomy and wound healing may foster suboptimal outcomes. We modified methods to address Asian features by extending subunit and flap boundaries, minimizing flap thinning, and overbuilding the nasal framework to combat contraction and suboptimal scarring. METHODS: Between November 2010 and September 2015, 40 Asians were treated for nasal reconstruction with a modified forehead flap technique...
May 2017: Plastic Surgery
https://www.readbyqxmd.com/read/29026565/supraventricular-microreentry-in-a-newborn-due-to-a-giant-atrial-septum-aneurysm
#18
Franziska Wagner, Roman Gebauer, Robert Wagner, Christian Paech
Supraventricular arrhythmias in neonates are rare and mostly not related to structural heart defects. We present the first case of a newborn with a supraventricular microreentrant tachycardia possibly associated with an atrial septum aneurysm and emphasize the importance of a thorough diagnostic workup allowing a fast and adequate therapy.
October 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29026559/verapamil-sensitive-atrial-tachycardia-with-a-slow-conduction-zone-near-the-noncoronary-aortic-sinus-and-his-bundle
#19
Osamu Inaba, Yasutoshi Nagata, Yasuteru Yamauchi, Takamichi Miyamoto, Masahiko Goya, Kenzo Hirao
This report presents a verapamil-sensitive atrial tachycardia, mid-atrium septum activating the earliest. Concealed entrainment was obtained at noncoronary aortic sinus (NCS), where the local activation was delayed compared to mid-septum. The tachycardia was successfully ablated at NCS. The entrance of the slow conduction zone was located at NCS.
October 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29026269/clinical-characteristics-of-septo-optic-dysplasia-accompanied-by-congenital-central-hypothyroidism-in-japan
#20
Keisuke Nagasaki, Takuo Kubota, Hironori Kobayashi, Hirotake Sawada, Chikahiko Numakura, Shohei Harada, Kei Takasawa, Kanshi Minamitani, Tomohiro Ishii, Satoshi Okada, Hotaka Kamasaki, Shigetaka Sugihara, Masanori Adachi, Toshihiro Tajima
Septo-optic dysplasia (SOD) is a congenital anomaly in which agenesis of the septum pellucidum and optic nerve hypoplasia are accompanied by hypopituitarism. Typically, the symptoms develop in 3 organs, the brain, eyes, and pituitary, and approximately one third of the patients present with all of the three cardinal features. The diagnostic criteria for SOD were established in Japan in 2015. The purpose of this study is to review clinical features regarding SOD patients with hypopituitarism in Japan. In this study, 21 patients with SOD were identified by a questionnaire survey for congenital central hypothyroidism...
2017: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
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