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https://www.readbyqxmd.com/read/29452069/idiopathic-isolated-unilateral-hypoglossal-nerve-palsy-a-report-of-2-cases-and-review-of-the-literature
#1
Akio Shibata, Masashi Kimura, Kenichiro Ishiabashi, Masahiro Umemura
Hypoglossal nerve palsy (HNP) is a common finding in neurologic diseases when associated with other cranial nerve palsies or further pathology and exhibits characteristic clinical manifestations, including unilateral atrophy of the musculature of the tongue. It occasionally appears as the initial or solitary sign of an intracranial or extracranial space-occupying lesion, head or neck injury, or vascular abnormality of the internal carotid artery. There are few cases of idiopathic isolated unilateral HNP, which should be diagnosed through exclusion...
February 2, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29450645/brain-c-fos-expression-patterns-induced-by-emotional-stressors-differing-in-nature-and-intensity
#2
Jesús Úbeda-Contreras, Ignacio Marín-Blasco, Roser Nadal, Antonio Armario
Regardless of its particular nature, emotional stressors appear to elicit a widespread and roughly similar brain activation pattern as evaluated by c-fos expression. However, their behavioral and physiological consequences may strongly differ. Here we addressed in adult male rats the contribution of the intensity and the particular nature of stressors by comparing, in a set of brain areas, the number of c-fos expressing neurons in response to open-field, cat odor or immobilization on boards (IMO). These are qualitatively different stressors that are known to differ in terms of intensity, as evaluated by biological markers...
February 15, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29448033/environmental-enrichment-decreases-avoidance-responses-in-the-elevated-t-maze-and-delta-fosb-immunoreactivity-in-anxiety-related-brain-regions
#3
Danielle A Lopes, Thaissa M O Souza, José S de Andrade, Mariana F S Silva, Hanna K M Antunes, Luciana Le Seur Maluf, Isabel C Céspedes, Milena B Viana
Environmental enrichment (EE) is an animal management technique, which seems to improve adaptation to the experimental conditions of housing in laboratory animals. Previous studies have pointed to different beneficial effects of the procedure in the treatment of several disorders, including psychiatric conditions such as depression. The anxiolytic effects induced by EE, on the other hand, are not as clear. In fact, it has been proposed that EE acts as a mild stressor agent. To better understand the relationship of EE with anxiety-related responses, the present study exposed rats to one week of EE and subsequently tested these animals in the inhibitory avoidance and escape tasks of the elevated T-maze (ETM)...
February 12, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29447758/nasolacrimal-anatomy-and-haplorhine-origins
#4
James B Rossie, Timothy D Smith, K Christopher Beard, Marc Godinot, Timothy B Rowe
Computed tomography X-ray imaging of the internal face in well-preserved primate fossil crania permits reconstruction of the nature of their nasal anatomy, including some soft-tissue features. These features are diagnostic of the primate suborder Haplorhini, and allow reevaluation of the phylogenetic status of several purported early members of the group. Here we examine the nasolacrimal morphology of a broad sample of extant primates, as well as a number of Paleogene fossils. The extant sample confirms the distinctiveness of the two suborders...
January 2018: Journal of Human Evolution
https://www.readbyqxmd.com/read/29447082/radiologic-measurement-of-brain-swelling-in-patients-with-large-hemispheric-infarctions-during-targeted-temperature-management
#5
Won Joo Jeong, Jae Seung Bang, Kyu Sun Yum, Sangkil Lee, Inyoung Chung, O-Ki Kwon, Chang Wan Oh, Beom Joon Kim, Hee-Joon Bae, Moon-Ku Han
Brain herniation is most often the result of severe brain swelling and can rapidly lead to death or brain death. We retrospectively identified radiologic indicators to evaluate the effects of targeted temperature management (TTM) on the extent of cerebral edema and determine the cutoff values that best predict TTM outcomes in patients with large hemispheric infarction. We retrospectively reviewed brain computed tomography (CT) scans of 21 patients with large hemispheric infarctions, who were treated with TTM...
February 15, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29445616/first-case-report-of-enzootic-nasal-adenocarcinoma-in-ouled-djellal-ewe-in-algeria
#6
Nassim Sid, Nour El Houda Belalmi, Louiza Benhamza, Soraya Ouhida, Mohammed Ezine Zebiri, Ahmet Aydoğan, Caroline Leroux
We report clinical and pathological features of enzootic nasal adenocarcinoma (ENA) in one sheep in Algeria. A one-year-old Ouled Djellal sheep from a large herd (~1240 animals), located in Bordj Bou Arreridj, Algeria, was clinically diagnosed by the presence of persistent seromucous nasal discharge, head shaking, muzzle licking, dyspnoea, exophthalmia and frontal protrusion. The sheep was euthanized, and the necropsy was performed. Gross examination showed soft touch, pinkish-white tumour masses in the nasal cavities with distortion of the turbinates and of the medium septum...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29445470/emergency-transcatheter-closure-of-a-stented-pda-in-a-patient-with-pulmonary-atresia-and-intact-ventricular-septum-be-ready-for-the-unexpected
#7
Alessia Faccini, Gianfranco Butera
Patients with congenital heart disease and duct-dependent pulmonary circulation can undergo stenting of the patent ductus arteriosus (PDA). This case shows that, due to the physiological changes occurring after stent implantation, sometimes it is necessary to close the stented PDA rather than to redilate it.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29444294/prognosis-of-adult-obstructive-hypertrophic-cardiomyopathy-patients-with-different-morphological-types-after-surgical-myectomy
#8
Bing Tang, Yunhu Song, Hao Cui, Keshan Ji, Qinjun Yu, Changsheng Zhu, Shihua Zhao, Shuiyun Wang
OBJECTIVES: This study aims to assess the impact of morphological type on the prognosis of obstructive hypertrophic cardiomyopathy patients who underwent myectomy. METHODS: We recruited 469 obstructive hypertrophic cardiomyopathy patients refractory to medicinal treatment who have undergone surgical myectomy at a nationwide referral centre. All patients were divided into 3 groups based on the morphological classification of left ventricular hypertrophy and were followed up by telephone every year...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29444216/long-term-outcomes-of-single-ventricle-palliation-for-pulmonary-atresia-with-intact-ventricular-septum-fontan-survivors-remain-at-risk-of-late-myocardial-ischaemia-and-death
#9
Patrick Elias, Chin Leng Poh, Karin du Plessis, Diana Zannino, Kathryn Rice, Dorothy J Radford, Andrew Bullock, Gavin R Wheaton, David S Celermajer, Yves d'Udekem
OBJECTIVES: The specific outcomes of patients with pulmonary atresia with intact ventricular septum late after Fontan palliation are unknown. Patients with smaller right ventricles and myocardial sinusoids are known to have worse survival in the first years of life. Whether the potential for coronary ischaemia affects the long-term outcomes of these patients after Fontan palliation is still unknown. METHODS: All patients with pulmonary atresia with intact ventricular septum who underwent the Fontan procedure from 1984 to 2016 in Australia and New Zealand were identified, and preoperative, perioperative and follow-up data were collected...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29443967/peptidoglycan-synthesis-drives-an-ftsz-treadmilling-independent-step-of-cytokinesis
#10
João M Monteiro, Ana R Pereira, Nathalie T Reichmann, Bruno M Saraiva, Pedro B Fernandes, Helena Veiga, Andreia C Tavares, Margarida Santos, Maria T Ferreira, Vânia Macário, Michael S VanNieuwenhze, Sérgio R Filipe, Mariana G Pinho
Peptidoglycan is the main component of the bacterial wall and protects cells from the mechanical stress that results from high intracellular turgor. Peptidoglycan biosynthesis is very similar in all bacteria; bacterial shapes are therefore mainly determined by the spatial and temporal regulation of peptidoglycan synthesis rather than by the chemical composition of peptidoglycan. The form of rod-shaped bacteria, such as Bacillus subtilis or Escherichia coli, is generated by the action of two peptidoglycan synthesis machineries that act at the septum and at the lateral wall in processes coordinated by the cytoskeletal proteins FtsZ and MreB, respectively...
February 14, 2018: Nature
https://www.readbyqxmd.com/read/29443451/use-of-an-autologous-bony-crossbar-graft-for-the-management-of-caudal-septal-deviation-our-experience-in-twenty-two-patients
#11
Yi-Chan Lee, Li-Ang Lee, Wei-Chieh Chao, Cheng-Ming Luo, Yi-Hsuan Lee, Shih-Wei Yang
Septoplasty for a deviated caudal septum is a technique challenging surgery. The two goals of surgery are adequate correction of the deviated septum and maintenance of the nasal tip structural support. Use of an autologous bony crossbar graft to correct a deviate caudal septum offers the following advantages. No difficult drilling or suturing procedure is needed because the graft was kept in place by the elastic properties of the buttonhole cartilage incisions. Second, a simple endonasal approach is sufficient to expose the entire surgical field...
February 14, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29442559/neural-mechanisms-of-navigation-involving-interactions-of-cortical-and-subcortical-structures
#12
James R Hinman, Holger Dannenberg, Andrew Alexander, Michael E Hasselmo
Animals must perform spatial navigation for a range of different behaviors, including selection of trajectories toward goal locations and foraging for food sources. To serve this function, a number of different brain regions play a role in coding different dimensions of sensory input important for spatial behavior, including the entorhinal cortex, the retrosplenial cortex, the hippocampus and the medial septum. This article will review data concerning the coding of the spatial aspects of animal behavior, including location of the animal within an environment, the speed of movement, the trajectory of movement, the direction of the head in the environment, and the position of barriers and objects both relative to the animal's head direction (egocentric) and relative to the layout of the environment (allocentric)...
February 14, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29441443/double-chambered-left-ventricle-a-heart-within-a-heart
#13
John D Gilbert, Roger W Byard
A 20-year-old previously well man drowned after performing a back-flip off a bridge into a river. At autopsy no significant injuries or organic illness were identified. An unusual incidental finding was a double chambered left ventricle, or so-called "heart within a heart", with the left ventricle subdivided into two separate chambers by a muscular septum. Awareness of this entity in forensic casework is important as this anomaly, despite its dramatic appearance, is not associated with anomalous conduction tracts or arrhythmogenic conditions, and so is usually a completely incidental finding at autopsy...
February 13, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29440842/coronary-sinus-atrial-septal-defect-without-persistent-left-superior-vena-cava-three-dimensional-imaging-of-a-rare-defect
#14
Sean Del-Rossi Quadros, Sreeja Pavithran, Ravi Agrawal, Kothandam Sivakumar
Coronary sinus defects refer to interatrial communications that lie out of the confines of the atrial septum and leads from left to right shunt through the ostium of the coronary sinus. When associated with persistent left superior vena cava (PLSVC), mild systemic desaturation may occur depending on the extent of unroofing of the coronary sinus. Isolated defects without PLSVC are rare. Three-dimensional echocardiographic and surgical images are presented.
January 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29439412/congenital-vomer-agenesis-a-rare-and-poorly-understood-condition-revealed-by-cone-beam-ct
#15
David Jun Yan, Vincent Lenoir, Sibylle Chatelain, Salvatore Stefanelli, Minerva Becker
Isolated congenital vomer agenesis is a very rare and poorly understood condition. In the context of dental work-up by cone-beam computed tomography (CBCT), the explored volume of the facial bones occasionally reveals incidental abnormalities. We report the case of a 13-year old Caucasian female who underwent CBCT for the pre-treatment evaluation of primary failure of tooth eruption affecting the permanent right upper and inferior molars. CBCT depicted a large defect of the postero-inferior part of the nasal septum without associated soft tissue abnormality and without cranio-facial malformation or cleft palate...
February 10, 2018: Diagnostics
https://www.readbyqxmd.com/read/29439241/near-infrared-deep-brain-stimulation-via-upconversion-nanoparticle-mediated-optogenetics
#16
Shuo Chen, Adam Z Weitemier, Xiao Zeng, Linmeng He, Xiyu Wang, Yanqiu Tao, Arthur J Y Huang, Yuki Hashimotodani, Masanobu Kano, Hirohide Iwasaki, Laxmi Kumar Parajuli, Shigeo Okabe, Daniel B Loong Teh, Angelo H All, Iku Tsutsui-Kimura, Kenji F Tanaka, Xiaogang Liu, Thomas J McHugh
Optogenetics has revolutionized the experimental interrogation of neural circuits and holds promise for the treatment of neurological disorders. It is limited, however, because visible light cannot penetrate deep inside brain tissue. Upconversion nanoparticles (UCNPs) absorb tissue-penetrating near-infrared (NIR) light and emit wavelength-specific visible light. Here, we demonstrate that molecularly tailored UCNPs can serve as optogenetic actuators of transcranial NIR light to stimulate deep brain neurons. Transcranial NIR UCNP-mediated optogenetics evoked dopamine release from genetically tagged neurons in the ventral tegmental area, induced brain oscillations through activation of inhibitory neurons in the medial septum, silenced seizure by inhibition of hippocampal excitatory cells, and triggered memory recall...
February 9, 2018: Science
https://www.readbyqxmd.com/read/29438999/characteristics-of-single-loop-macroreentrant-biatrial-tachycardia-diagnosed-by-ultrahigh-resolution-mapping-system
#17
Takeshi Kitamura, Ruairidh Martin, Arnaud Denis, Masateru Takigawa, Alexandre Duparc, Anne Rollin, Antonio Frontera, Nathaniel Thompson, Gregoire Massoullié, Ghassen Cheniti, Michael Wolf, Konstantinos Vlachos, Claire A Martin, Nora Al Jefairi, Josselin Duchateau, Nicolas Klotz, Thomas Pambrun, Frédéric Sacher, Hubert Cochet, Meleze Hocini, Michel Haïssaguerre, Philippe Maury, Pierre Jaïs, Nicolas Derval
BACKGROUND: Biatrial tachycardia (BiAT) is a rare form of atrial macroreentrant tachycardia, in which both atria form a critical part of the circuit. We aimed to identify the characteristics and precise circuits of single-loop macroreentrant BiATs. METHODS AND RESULTS: We identified 8 patients (median age, 59.5 years old) with 9 BiATs in a cohort of 336 consecutive patients from 2 institutions who had undergone AT catheter ablation using an automatic ultrahigh-resolution mapping system...
February 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29438201/location-of-the-septoaponeurosis-junction-relative-to-the-tarsal-plate-in-upper-eyelids
#18
Kun Hwang, Seong Kyung Yoo, Dae Joong Kim
The aim of this study was to measure the location of the septoaponeurosis junction relative to the tarsal plate in the upper eyelids of Koreans through a histologic study.Thirty-four upper eyelids from 34 Korean adult cadavers (mean age, 77.8 years) were used. Sagittal sections on the midpupillary line were made, and 10-μm-thick sections were prepared and stained with hematoxylin-eosin and Masson trichrome. Under a magnifying loupe with a scale, the height of the tarsal plate (HTP), thickness of the tarsal plate (TTP), distance from the lid margin to the septoaponeurosis junction (MJD), and distance from the upper border of the tarsal plate to the septoaponeurosis junction (TJD) were measured...
February 12, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29437500/use-of-the-sphenoid-flap-in-repair-of-the-wide-cleft-palate
#19
Khurram Khan, Joseph Hardwicke, Rimante Seselgyte, Paul Morris, Guy Thorburn, Loshan Kangesu, Marc C Swan, Bruce Richard
OBJECTIVE: In wide palatal defects, closure of the nasal layer can prove a considerable challenge. Mobilizing nasal flaps posteriorly usually facilitates soft palate closure. However, the defect is often too wide within the hard palate; hence, bilateral vomerine flaps are frequently required. Despite this, there is often a small defect in the nasal layer at the posterior septum (typically equating to the hard-soft palate junction), which has to be left to heal by secondary intention with the resulting increased risk of fistula formation and the potential deleterious long-term effect on speech due to cicatricial migration of the reconstructed levator sling anteriorly...
March 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29432905/transvaginal-single-port-laparoscopy-pelvic-reconstruction-with-y-shaped-mesh
#20
Yisong Chen, Junwei Li, Keqin Hua
STUDY OBJECTIVE: To describe new technique of pelvic reconstruction with Y-shaped mesh assisted by transvaginal single-port laparoscopy for multiple compartments Pelvic Organ Prolapse (POP). DESIGN: Step-by-step explanation of the procedure using video. SETTING: It is more and more prudent for pelvic floor reconstruction with mesh because of mesh related complications. Learning from sacrocolpopexy with lower rate of mesh erosion (3.5%), new method of pelvic reconstruction with natural orifice transluminal endoscopic surgery is feasible...
February 9, 2018: Journal of Minimally Invasive Gynecology
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