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https://www.readbyqxmd.com/read/28335236/complex-morphology-metal-based-nanostructures-fabrication-characterization-and-applications
#1
REVIEW
Antonella Gentile, Francesco Ruffino, Maria Grazia Grimaldi
Due to their peculiar qualities, metal-based nanostructures have been extensively used in applications such as catalysis, electronics, photography, and information storage, among others. New applications for metals in areas such as photonics, sensing, imaging, and medicine are also being developed. Significantly, most of these applications require the use of metals in the form of nanostructures with specific controlled properties. The properties of nanoscale metals are determined by a set of physical parameters that include size, shape, composition, and structure...
June 6, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28333853/multimodal-imaging-in-vortex-vein-varices
#2
Chiara Veronese, Giovanni Staurenghi, Marco Pellegrini, Chiara Maiolo, Laura Primavera, Mariachiara Morara, Grayson W Armstrong, Antonio P Ciardella
PURPOSE: The aim of this study is to describe the clinical presentation of vortex vein varices with multimodal imaging. METHODS: The authors carried out a retrospective case series of eight patients (7 female, 1 male) with an average age of 60.2 years (min 8, max 84, median 68.5) presenting with vortex vein varices. All patients were evaluated at the Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy and at Luigi Sacco Hospital, University of Milan, Milan, Italy...
March 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28333635/blind-facial-image-quality-enhancement-using-non-rigid-semantic-patches
#3
Ester Hait, Guy Gilboa
We propose a new way to solve a very general blind inverse problem of multiple simultaneous degradations such as blur, resolution reduction, noise and contrast changes, without explicitly estimating the degradation. The proposed concept is based on combining semantic non-rigid patches, problem-specific high quality prior data and non-rigid registration tools. We show how a significant quality enhancement can be achieved, both visually and quantitatively, in the case of facial images. The method is demonstrated on the problem of cellular photography quality enhancement of dark facial images for different identities, expressions and poses, and is compared to state-of-the-art denoising, deblurring, super-resolution and colorcorrection methods...
March 22, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28326562/liposome-encapsulated-hemoglobin-accelerates-skin-wound-healing-in-diabetic-db-db-mice
#4
Tsuyoshi Fukui, Akira T Kawaguchi, Susumu Takekoshi, Muneo Miyasaka, Hideaki Sumiyoshi, Rica Tanaka
Since liposome-encapsulated hemoglobin with high O2 affinity (h-LEH, P50 O2  = 10 mm Hg) has been reported to accelerate skin wound healing in normal mice, it was tested in dB/dB mice with retarded wound healing, as seen in human diabetics. Two full-thickness dorsal wounds 6 mm in diameter encompassed by silicone stents were created in dB/dB mice. Two days later (day 2), the animals were randomly assigned to receive intravenous h-LEH (2 mL/kg, n = 7) or saline (2 mL/kg, n = 7). The same treatment was repeated 4 days after wounding (day 4), and the size of the skin lesions was analyzed by photography, surface perfusion was detected by Laser-Doppler imager, and plasma cytokines and chemokines were determined on days 0, 2, 4, and 7, when all animals were euthanized for morphological studies...
March 21, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28324111/arap1-deficiency-causes-photoreceptor-degeneration-in-mice
#5
Ala Moshiri, Devin Humpal, Brian C Leonard, Denise M Imai, Addy Tham, Lynette Bower, Dave Clary, Thomas M Glaser, K C Kent Lloyd, Christopher J Murphy
Purpose: Small guanosine triphosphatase (GTPase) ADP-ribosylation factors (Arfs) regulate membrane traffic and actin reorganization under the control of GTPase-activating proteins (GAPs). Arap1 is an Arf-directed GAP that inhibits the trafficking of epidermal growth factor receptor (EGFR) to the early endosome, but the diversity of its functions is incompletely understood. The aim of this study was to determine the role of Arap1 in the mammalian retina. Methods: Genetically engineered Arap1 knockout mice were screened for ocular abnormalities in the National Institutes of Health Knockout Mouse Production and Phenotyping (KOMP2) Project...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28323650/optimizing-smartphones-for-clinical-photography
#6
Marc K Rubenzik, Wesley J Wu, Blake R Zelickson, Leonard H Goldberg
No abstract text is available yet for this article.
March 17, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28322323/anti-inflammatory-properties-of-shikonin-contribute-to-improved-early-stage-diabetic-retinopathy
#7
Po-Lin Liao, Cheng-Hui Lin, Ching-Hao Li, Chi-Hao Tsai, Jau-Der Ho, George C Y Chiou, Jaw-Jou Kang, Yu-Wen Cheng
Diabetic retinopathy (DR), a major microvascular complication of diabetes, leads to retinal vascular leakage, neuronal dysfunction, and apoptosis within the retina. In this study, we combined STZ with whole-body hypoxia (10% O2) for quicker induction of early-stage retinopathy in C57BL/6 mice. We also compared the effects of a high glucose condition combined with hypoxia (1% O2) to a low glucose condition by using retinal pigment epithelial (RPE) cells, which are a crucial component of the outer blood-retinal barrier and the damage is related to retinopathy...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28320482/pressure-relieving-support-surfaces-a-randomised-evaluation-2-pressure-2-photographic-validation-sub-study-study-protocol-for-a-randomised-controlled-trial
#8
Elizabeth McGinnis, Sarah Brown, Howard Collier, Phil Faulks, Rachael Gilberts, Clare Greenwood, Valerie Henderson, Delia Muir, Andrea Nelson, Jane Nixon, Isabelle Smith, Nikki Stubbs, Kay Walker, Lyn Wilson, Susanne Coleman
BACKGROUND: PRESSURE 2 is a randomised evaluation of the clinical and cost effectiveness of two types of pressure relieving mattress for the prevention of pressure ulcers. The primary endpoint is the time to development of a Category ≥2 pressure ulcer. The current 'gold standard' for the identification of a Category ≥2 pressure ulcer is expert clinical assessment. Due to the appearance of the bed, it is not possible to achieve blinding of the endpoint. This therefore poses a risk to the internal validity of the study...
March 20, 2017: Trials
https://www.readbyqxmd.com/read/28314833/retinopathy-in-an-obesity-who-iii-cohort-prevalence-and-risk-factors
#9
Juri Mattern, Alexander Lammert, Mirko Otto, Hans-Peter Hammes
OBJECTIVE: To assess retinopathy and its risk factors in an obesity WHO III cohort. METHODS: In the Mannheim Obesity Study, 277 subjects with obesity WHO III aged 18-64 years were examined in a cross-sectional approach. Screening for retinopathy was performed using 3-field retinal photography. Endothelial function was assessed using arteriole-to-venule ratio and flicker light analysis. Subjects with and without retinopathy were analysed for anthropometry, metabolic, vascular and renal parameters...
March 17, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28306635/ocular-fundus-photography-with-a-smartphone-device-in-acute-hypertension
#10
M Lorenza Muiesan, Massimo Salvetti, Anna Paini, Michela Riviera, Clara Pintossi, Fabio Bertacchini, Efrem Colonetti, Claudia Agabiti-Rosei, Maurizio Poli, Francesco Semeraro, Enrico Agabiti-Rosei, Andrea Russo
BACKGROUND: The ocular fundus examination is infrequently and poorly performed in the emergency department (ED) clinical settings, placing patients at risk for missed diagnosis of hypertensive emergencies. The aim of this study was to investigate the feasibility of the ocular fundus photography with a smartphone small optical device in an ED setting and to compare it with a traditional ocular fundus examination. METHODS: The study included 52 consecutive patients (mean age 69 ± 16 years, 50% women) presenting to a hospital ED with an acute increase in blood pressure (SBP > 180 and/or DBP > 100 mmHg)...
March 16, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28303676/differences-in-respiratory-arousal-threshold-in-caucasian-and-chinese-patients-with-obstructive-sleep-apnoea
#11
Richard W W Lee, Kate Sutherland, Scott A Sands, Bradley A Edwards, Tat On Chan, Susanna S S Ng, David S Hui, Peter A Cistulli
BACKGROUND AND OBJECTIVE: Ethnic differences in obstructive sleep apnoea (OSA) phenotype may not be limited to obesity and craniofacial factors. The aims of the study were to (i) compare the proportion of Caucasians and Chinese patients with a low respiratory arousal threshold (ArTH) and (ii) explore the influence of anatomical compromise on ArTH. METHODS: Interethnic comparison was conducted between cohorts of Caucasian and Chinese patients from specialist sleep disorder clinics...
March 16, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28301857/structural-and-functional-characterization-of-benign-fleck-retina-using-multimodal-imaging
#12
Srividya Neriyanuri, Chetan Rao, Rajiv Raman
PURPOSE: To report structural and functional features in a case series of benign fleck retina using multimodal imaging. METHODS: Four cases with benign fleck retina underwent complete ophthalmic examination that included detailed history, visual acuity, and refractive error testing, FM-100 hue test, dilated fundus evaluation, full field electroretinogram, fundus photography with autofluorescence, fundus fluorescein angiography, and swept-source optical coherence tomography...
April 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28301651/quantification-of-retinal-microvascular-density-in-optical-coherence-tomographic-angiography-images-in-diabetic-retinopathy
#13
Mary K Durbin, Lin An, Nathan D Shemonski, Mário Soares, Torcato Santos, Marta Lopes, Catarina Neves, Jose Cunha-Vaz
Importance: Quantitative measurements based on optical coherence tomographic angiography (OCTA) may have value in managing diabetic retinopathy (DR), but there is limited information on the ability of OCTA to distinguish eyes with DR. Objective: To evaluate the ability of measurements of retinal microvasculature using OCTA to distinguish healthy eyes from eyes with DR. Design, Setting, and Participants: In this prospective cross-sectional study, OCTA was used to examine the eyes of participants with type 2 diabetes with or without DR and the eyes of participants without diabetes from September 17, 2015, to April 6, 2016...
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301622/expert-consensus-on-cosmetic-outcomes-after-treatment-of-actinic-keratosis
#14
Brian Berman, Glynis R Ablon, Neal D Bhatia, Roger I Ceilley, David J Goldberg, Mark S Nestor, Susan H Weinkle
<p>Dermatologists treat actinic keratosis (AK) primarily because these lesions have the potential to progress to invasive squamous cell carcinoma. Patients, on the other hand, generally seek treatment to remove the lesions and achieve an improved appearance of their skin following treatment. In selecting a treatment option for AK, dermatologists should consider post-treatment cosmesis, because cosmetic outcomes differ across AK treatments. To obtain expert opinion on the cosmetic sequelae related to chronically photodamaged skin and the treatment of AK, an expert panel meeting among dermatologists was conducted in February 2016...
March 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28301411/retinal-phenotype-in-a-case-of-lchad-tfp-deficiency-with-late-stage-diagnosis
#15
Jacob A Knowles, Ioannis S Dimopoulos, Ian M MacDonald
PURPOSE: To report the retinal phenotype of a rare case of long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD)/trifunctional protein (TFP) deficiency diagnosed in his late 40s with ocular findings of diffuse chorioretinal atrophy and bilateral retinoschisis. METHODS: An acylcarnitine profile assay revealed LCHAD/TFP deficiency in a 45-year-old man with a history of high myopia, bilateral decreased vision, episodic rhabdomyolysis, and peripheral neuropathy. Ocular findings were evaluated with spectral domain optical coherence tomography (Spectralis OCT; Heidelberg Engineering, Heidelberg, Germany) and color fundus photography...
March 15, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28300713/low-cost-smartphone-based-photogrammetry-for-the-analysis-of-cranial-deformation-in-infants
#16
Inés Barbero-García, José Luis Lerma, Ángel Marqués-Mateu, Pablo Miranda
BACKGROUND: Cranial deformation, including deformational plagiocephaly, brachycephaly and craniosynostosis, is a condition that affects a large number of infants. Despite of its prevalence there are no standards for the systematic evaluation of the cranial deformation. Usually, the deformation is manually measured using callipers. However, experts do not agree on the suitability of these measurements to correctly represent the deformation. Other methodologies for evaluation include 3D photography and radiologic scanners...
March 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28300477/evaluation-of-intracameral-pentablock-copolymer-thermosensitive-gel-for-sustained-drug-delivery-to-the-anterior-chamber-of-the-eye
#17
Elizabeth Schaefer, Sara M Smith, Jacklyn Salmon, Santhi Abbaraju, Rasidul Amin, Sidney Weiss, Ulrich Grau, Poonam Velagaleti, Brian Gilger
PURPOSE: To investigate PTSgels (Pentablock copolymers) as an injectable formulation technology for sustained ocular drug delivery. Drug release profile, tolerability, and polymer degradation for one of the thermosensitive, biodegradable, and biocompatible compositions were investigated through intracameral (IC) injection in rabbits. METHODS: New Zealand White rabbit eyes were injected IC (50 μL) with 100 μg near-infrared-immunoglobulin G (NIR-IgG) in balanced salt solution (BSS) or 20% PTSgel; or with PTSgel or BSS alone...
March 16, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28300146/a-rapid-screening-approach-to-detect-and-quantify-microplastics-based-on-fluorescent-tagging-with-nile-red
#18
Thomas Maes, Rebecca Jessop, Nikolaus Wellner, Karsten Haupt, Andrew G Mayes
A new approach is presented for analysis of microplastics in environmental samples, based on selective fluorescent staining using Nile Red (NR), followed by density-based extraction and filtration. The dye adsorbs onto plastic surfaces and renders them fluorescent when irradiated with blue light. Fluorescence emission is detected using simple photography through an orange filter. Image-analysis allows fluorescent particles to be identified and counted. Magnified images can be recorded and tiled to cover the whole filter area, allowing particles down to a few micrometres to be detected...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28299700/dynamic-antibiotic-susceptibility-test-via-a-3d-microfluidic-culture-device
#19
Zining Hou, Yu An, Zhigang Wu
This study presents a novel microfluidic approach to the investigation of bacterial susceptibility against antibiotics gradient concentration in a quantitative way. A linear concentration gradient of antibiotics in a microfluidic chamber is used with time-lapse photography. This approach provides high-resolution information in real time. Traditional tests for this type of study involve Clinical and Laboratory Standard Institute (CLSI) recommended test and Etest. All of these tests need different trials to present different concentrations...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28297034/the-role-of-posterior-vitreous-detachment-and-vitreomacular-adhesion-in-patients-with-age-related-macular-degeneration
#20
Orhan Ilim, Cezmi Akkin, Zafer Oztas, Serhad Nalcaci, Filiz Afrashi, Cumali Degirmenci, Jale Mentes
BACKGROUND AND OBJECTIVE: The aim of this study was to assess the prevalence of posterior vitreous detachment (PVD) and vitreoretinal interface in patients with age-related macular degeneration (AMD). PATIENTS AND METHODS: This clinical trial included 206 eyes of 138 patients who presented to the authors' clinic between January 2012 and November 2014. Patients were divided into three groups: 98 eyes of 67 patients with exudative AMD, 55 eyes of 36 patients with nonexudative AMD, and 53 eyes of 35 patients having no vitreoretinal disease...
March 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
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