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https://www.readbyqxmd.com/read/29777982/documentation-and-analysis-of-traumatic-injuries-in-clinical-forensic-medicine-involving-structured-light-three-dimensional-surface-scanning-versus-photography
#1
Awatif Shamata, Tim Thompson
Non-contact three-dimensional (3D) surface scanning has been applied in forensic medicine and has been shown to mitigate shortcoming of traditional documentation methods. The aim of this paper is to assess the efficiency of structured light 3D surface scanning in recording traumatic injuries of live cases in clinical forensic medicine. The work was conducted in Medico-Legal Centre in Benghazi, Libya. A structured light 3D surface scanner and ordinary digital camera with close-up lens were used to record the injuries and to have 3D and two-dimensional (2D) documents of the same traumas...
May 10, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29772051/optical-coherence-tomography-angiography-of-pigmented-paravenous-retinochoroidal-atrophy
#2
Maria Vittoria Cicinelli, Chiara Giuffrè, Alessandro Rabiolo, Maurizio Battaglia Parodi, Francesco Bandello
A 58-year-old man with bilateral pigmented paravenous retinochoroidal atrophy (PPRCA) associated with macular coloboma in the right eye underwent color fundus photography and fundus autofluorescence with the California ultra-widefield retinal imaging system (Optos, Dunfermline, UK), spectral-domain optical coherence tomography (SD-OCT) (Heidelberg Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany), and en face OCT angiography (OCTA) (AngioPlex, Cirrus HD-OCT 5000; Carl Zeiss Meditec, Dublin, CA)...
May 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29772044/a-phase-1-open-label-dose-escalation-trial-to-investigate-safety-and-tolerability-of-single-intravitreous-injections-of-icon-1-targeting-tissue-factor-in-wet-amd
#3
John A Wells, Christine R Gonzales, Brian B Berger, Victor H Gonzalez, Brian D Sippy, Gabriela Burian
BACKGROUND AND OBJECTIVE: This phase 1 study evaluated the safety and tolerability of single intravitreous injections (IVIs) of ICON-1 (Iconic Therapeutics, South San Francisco, CA) in patients with neovascular age-related macular degeneration (nAMD). ICON-1 is a modified factor VIIa protein linked with the Fc portion of a human immunoglobulin G1. The molecule binds tissue factor overexpressed on choroidal neovascularization (CNV) in AMD. PATIENTS AND METHODS: Open-label, interventional, dose-escalation trial in 18 patients with CNV due to AMD, with six patients per dose cohort...
May 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29770904/deferoxamine-induced-electronegative-erg-responses
#4
Ruben Jauregui, Karen Sophia Park, Alexander G Bassuk, Vinit B Mahajan, Stephen H Tsang
PURPOSE: To report a case of deferoxamine-induced retinopathy characterized by electroretinography (ERG), optical coherence tomography angiography (OCT-A), and other multimodal imaging. METHODS: This is an observational case report of one patient. Full-field ERG was performed. OCT-A, spectral-domain optical coherence tomography (SD-OCT), color fundus photography, and fundus autofluorescence were used to characterize the retinopathy induced by deferoxamine use. RESULTS: A 64-year-old man with a history of β-thalassemia intermedia presented with worsening visual acuity, nyctalopia, and electronegative ERG...
May 16, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29769300/schlieren-photography-on-freely-flying-hawkmoth
#5
Yun Liu, Jesse Roll, Stephen Van Kooten, Xinyan Deng
The aerodynamic force on flying insects results from the vortical flow structures that vary both spatially and temporally throughout flight. Due to these complexities and the inherent difficulties in studying flying insects in a natural setting, a complete picture of the vortical flow has been difficult to obtain experimentally. In this paper, Schlieren , a widely used technique for highspeed flow visualization, was adapted to capture the vortex structures around freely flying hawkmoth ( Manduca ). Flow features such as leading-edge vortex, trailing-edge vortex, as well as the full vortex system in the wake were visualized directly...
May 2018: Biology Letters
https://www.readbyqxmd.com/read/29764241/lack-of-respiratory-and-ocular-effects-following-acute-propylene-glycol-exposure-in-healthy-humans
#6
Pamela Dalton, Brianna Soreth, Christopher Maute, Carolyn Novaleski, Marcy Banton
OBJECTIVE: Propylene glycol (PG) is a widely used solvent, chemical intermediate and carrier substance for foods, pharmaceutical and cosmetic products. Professional and occupational exposure to PG aerosol and vapor may occur from theatrical smoke generators and during application of deicing products to airplanes. While PG is considered to have low toxicity, the results of one study suggested that brief (1-min) exposure to PG mist elicited ocular and respiratory effects in humans. Because the high concentrations and brief exposure duration in that study were not representative of most occupational exposures, a controlled experimental exposure study was conducted to clarify or confirm the earlier findings...
May 15, 2018: Inhalation Toxicology
https://www.readbyqxmd.com/read/29762437/primary-premaxillary-ostectomy-and-setback-dealing-with-the-fly-away-premaxilla
#7
Rana Farhadi, Robert D Wallace
OBJECTIVE: This study aimed to analyze our outcomes of primary premaxillary ostectomy and setback combined with lip adhesion as the first stage in repair of the bilateral cleft lip with fly-away premaxilla. METHODS: This retrospective study included all patients who required primary premaxillary setback by a single surgeon to achieve successful lip repair between 2011 and 2017 at a tertiary children's hospital. All patients had bilateral cleft lip and complete cleft palate with significant premaxillary protrusion...
May 14, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29762117/smartphone-photography-as-a-tool-to-measure-knee-range-of-motion
#8
Megan Conti Mica, Eric R Wagner, Alexander Y Shin
The objective of this study was to validate measuring knee range of motion (ROM) from smartphone photography. Thirty-two participants (64 knees) obtained smartphone photographs of knee flexion and extension. Surgeons obtained the same photographs and goniometric measurement of ROM. ROM was measured using Adobe Photoshop. Goniometer versus digital measurements, participant versus surgeon photographs, and interobserver measurements were analyzed. The average difference in goniometer and digital photograph measurements was 5°...
2018: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/29761600/loss-of-angiotensin-converting-enzyme-2-exacerbates-diabetic-retinopathy-by-promoting-bone-marrow-dysfunction
#9
Yaqian Duan, Eleni Beli, Sergio Li Calzi, Judith L Quigley, Rehae C Miller, Leni Moldovan, Dongni Feng, Tatiana E Salazar, Sugata Hazra, Jude Al-Sabah, Kakarla V Chalam, Thao Le Phuong Trinh, Marya Meroueh, Troy A Markel, Matthew C Murray, Ruchi J Vyas, Michael E Boulton, Patricia Parsons-Wingerter, Gavin Y Oudit, Alexander G Obukhov, Maria B Grant
Angiotensin-converting enzyme 2 (ACE2) is the primary enzyme of the vasoprotective axis of the renin angiotensin system (RAS). We tested the hypothesis that loss of ACE2 would exacerbate diabetic retinopathy by promoting bone marrow dysfunction. ACE2-/y were crossed with Akita mice, a model of type 1 diabetes. When comparing the bone marrow of the ACE2-/y -Akita mice to that of Akita mice, we observed a reduction of both short-term and long-term repopulating hematopoietic stem cells, a shift of hematopoiesis towards myelopoiesis, and an impairment of lineage- c-kit+ hematopoietic stem/progenitor cell (HS/PC) migration and proliferation...
May 15, 2018: Stem Cells
https://www.readbyqxmd.com/read/29760821/a-mini-review-of-using-the-oralift-appliance-and-a-pilot-study-to-see-if-3d-imaging-techniques-could-improve-outcomes
#10
REVIEW
N K Mohindra
Background: Occlusal appliances of various designs have been described in the literature. They usually have to be worn for substantial periods including night time to have the desired effect for which they are designed. The Oralift® appliance has been designed to address the signs of facial ageing and to help stop parafunctional habits. The appliance is based on the principles of the pivot appliance and is worn for very short periods, never at night and not even every day. The maximum usage recommended is two hours every third day...
2018: Open Dentistry Journal
https://www.readbyqxmd.com/read/29760741/establishing-a-surgical-procedure-for-rhesus-epiretinal-scaffold-implantation-with-hipsc-derived-retinal-progenitors
#11
Ziming Luo, Kang Li, Kaijing Li, Bikun Xian, Ying Liu, Sijing Yang, Chaochao Xu, Zhigang Fan, Shoutao Lu, Haijun Zhang, Jian Ge
Background: To develop an effective surgical procedure for cellular scaffold epiretinal implantation in rhesus, facilitating subsequent epiretinal stem cell transplantation. Methods: Retinal progenitors were seeded onto a poly(lactic-co-glycolic) acid (PLGA) scaffold. First, the cellular scaffolds were delivered by 18G catheter or retinal forceps into rabbit epiretinal space ( n = 50). Then, the cell survival rate was evaluated by Cell Counting Kit-8 (CCK-8). Second, three methods of scaffold fixation, including adhesion after gas-liquid exchange ( n = 1), tamponade by hydrogel ( n = 1), and fixation by retinal tacks ( n = 4), were performed in rhesus monkeys...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29758447/experimental-sharp-force-injuries-to-ribs-multimodal-morphological-and-geometric-morphometric-analyses-using-micro-ct-macro-photography-and-sem
#12
Larissa Komo, Martin Grassberger
Tool marks on bones induced by knife blades can be analysed morphometrically in order to enable an allocation of the suspected "inflicting weapon" to the particular morphology of the bone lesions. Until now, geometric morphometrics has not been used to analyse the morphology of knife lesions on fleshed bones in detail. By using twelve experimental knives and a drop weight tower, stab/cut injuries were inflicted on untreated pig ribs. The morphology of the experimentally produced lesions was subsequently recorded with three imaging techniques (μCT, macro photography and SEM) and analysed with different morphometric software (Amira, tps and Morpheus)...
May 1, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29755818/retinal-angiomatous-proliferation-multimodal-imaging-characteristics-and-follow-up-with-eye-tracked-spectral-domain-optical-coherence-tomography-of-precursor-lesions
#13
Zafer Öztaş, Jale Menteş
Objectives: To present the multimodal imaging characteristics of precursor retinal angiomatous proliferation (RAP) lesions and follow-up results with eye-tracked spectral-domain optical coherence tomography (SD-OCT). Materials and Methods: Six eyes of 6 patients aged 77.5±5.9 years diagnosed with precursor RAP lesion were included in this prospective observational case series. Best corrected visual acuity (BCVA) measurement and complete ophthalmologic examination were performed for all subjects, as well as fundus photography (FP), fundus autofluorescence (FAF), SD-OCT, fluorescein angiography (FA), indocyanine green angiography (ICGA), optical coherence tomography angiography (OCTA), and their long-term follow-up results are presented...
April 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29754783/therapeutic-spaces-of-care-farming-transformative-or-ameliorating
#14
Alexandra Kaley, Chris Hatton, Christine Milligan
Since Wil Gesler's earliest articulation (Gesler, 1992; Gesler, 1996) key thinkers in the field of therapeutic landscapes have sought to emphasise the embodied, contextual and wholly relational nature of the relationship that exists between people and place. However, the extant research has tended to focus on the relational healing experience as this occurs 'in the moment' and with reference to a specific location or site of healing, with less attention being paid to what happens to people when they return to their ordinary or everyday places...
May 4, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29754205/context-dependent-crypsis-a-prey-s-perspective-of-a-color-polymorphic-predator
#15
D Rodríguez-Morales, V Rico-Gray, J G García-Franco, H Ajuria-Ibarra, L T Hernández-Salazar, L E Robledo-Ospina, D Rao
Many animals use body coloration as a strategy to communicate with conspecifics, prey, and predators. Color is a trade-off for some species, since they should be visible to conspecifics but cryptic to predators and prey. Some flower-dwelling predators, such as crab spiders, are capable of choosing the color of flowers where they ambush flower visitors and pollinators. In order to avoid being captured, visitors evaluate flowers visually before landing. The crab spider Mecaphesa dubia is a polymorphic species (white/purple color morphs), which inhabits the flower heads of a dune plant, Palafoxia lindenii...
May 12, 2018: Die Naturwissenschaften
https://www.readbyqxmd.com/read/29753852/color-fundus-photography-optical-coherence-tomography-and-fluorescein-angiography-in-diagnosing-polypoidal-choroidal-vasculopathy
#16
Voraporn Chaikitmongkol, Preeyanuch Khunsongkiet, Direk Patikulsila, Mansing Ratanasukon, Nawat Watanachai, Chaisiri Jumroendararasame, Catherine B Mayerle, Ian C Han, Connie J Chen, Pawara Winaikosol, Chutikarn Dejkriengkraikul, Janejit Choovuthayakorn, Paradee Kunavisarut, Neil M Bressler
PURPOSE: To determine sensitivity and specificity of polypoidal choroidal vasculopathy (PCV) diagnosis using color fundus photography (CFP), optical coherence tomography (OCT) and fundus fluorescein angiography (FFA) without indocyanine-green angiography (ICGA). DESIGN: Validity analysis. METHODS: Treatment-naïve eyes with serous/serosanguinous maculopathy undergoing CFP, OCT, FFA and ICGA imaging before treatment at a university-hospital in Thailand (January 2013 to June 2015) were identified...
May 10, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29749697/canine-and-feline-fundus-photography-and-videography-using-a-nonpatented-3d-printed-lens-adapter-for-a-smartphone
#17
Filipe Espinheira Gomes, Eric Ledbetter
OBJECTIVE: To describe an indirect funduscopy imaging technique for dogs and cats using low cost and widely available equipment: a smartphone, a three-dimensional (3D) printed indirect lens adapter, and a 40 diopters (D) indirect ophthalmoscopy lens. METHODS: Fundus videography was performed in dogs and cats using a 40D indirect ophthalmoscopy lens and a smartphone fitted with a 3D printed indirect lens adapter. All animals were pharmacologically dilated with topical tropicamide 1% solution...
May 11, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29749240/why-is-it-necessary-to-examine-retina-when-the-patient-suffers-from-aplastic-anemia
#18
D Tomcikova, A Gerinec, B Busanyova, M Gresikova, S Biskup, K Hortnagel
PURPOSES: To inform about a case of Revesz syndrome (RS) with initial ophthalmological symptomatology of severe proliferative vitreoretinopathy of the left eye (LE). After the aplastic anemia had developed, RS was established. The exudative retinopathy was successfully treated with photocoagulation on the right eye (RE). BACKGROUND: RS is characterized by fatal bone marrow failure, exudative retinopathy, neuroradiographic abnormalities, neurodevelopmental delay and skin abnormalities...
2018: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29747621/prevalence-and-clinical-characteristics-of-dry-eye-disease-in-community-based-type-2-diabetic-patients-the-beixinjing-eye-study
#19
Xinrong Zou, Lina Lu, Yi Xu, Jianfeng Zhu, Jiangnan He, Bo Zhang, Haidong Zou
BACKGROUND: This study was performed to evaluate the prevalence and clinical characteristics of dry eye disease (DED) in community-based type 2 diabetic patients and to identify the associated factors related with DED. METHODS: A total of 1360 type 2 diabetic patients in the Beixinjing community were randomly selected. All participants were given a questionnaire that assessed basic information and subjective symptoms.DED was diagnosed using the revised Japanese DED diagnostic criteria...
May 10, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29746403/amish-eye-study-baseline-spectral-domain-optical-coherence-tomography-characteristics-of-age-related-macular-degeneration
#20
Muneeswar G Nittala, Yeunjoo E Song, Rebecca Sardell, Larry D Adams, Samuel Pan, Swetha B Velaga, Violet Horst, Debra Dana, Laura Caywood, Renee Laux, Denise Fuzzell, Sarada Fuzzell, William K Scott, Jessica N Cooke Bailey, Robert P Igo, Jonathan Haines, Margaret A Pericak-Vance, SriniVas R Sadda, Dwight Stambolian
PURPOSE: To describe spectral domain optical coherence tomography (SD-OCT) findings in an Amish cohort to assess SD-OCT markers for early age-related macular degeneration (AMD). METHODS: The authors performed a family-based prospective cohort study of 1,146 elderly Amish subjects (age range 50-99 years) (2,292 eyes) who had a family history of at least 1 individual with AMD. All subjects underwent complete ophthalmic examinations, SD-OCT using both Cirrus and Spectralis (20 × 20° scan area) instruments, fundus autofluorescence, infrared imaging, and color fundus photography...
May 9, 2018: Retina
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