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Primary cilliary dyskinesia

D C Arunabha, R T Sumit, B Sourin, C Sabyasachi, M Subhasis
BACKGROUND: Recurrent lower respiratory tract infection (LRTI) is a very common problem we encounter in our clinical practice. Failure to recognize the specific cause of this condition may subject the patients to unnecessary and inappropriate treatment. CASE DETAILS: among the various causes of recurrent LRTI, the most frequent causes are abnormalities of general or local impairment of immune mechanism and abnormalities of cilia or mucus of respiratory tract. We report an adult case of recurrent upper and lower respiratory tract infections since childhood along with situs inversus totalis which was diagnosed as Kartagener's syndrome...
October 2014: Ethiopian Journal of Health Sciences
Shiri Guy-Alfandary, Barak Nahir, Yifat Namer-Tal, Meir Raz
SESSION TYPE: Asthma PostersPRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PMPURPOSE: To describe Omalizumab clinical utilization pattern and its effectiveness in Maccabi Healthcare Organization and to determine the need for a clinical decision tool as well as a control system for prescribing and administering Omalizumab in everyday practice.METHODS: 109 patients, treated with Omalizumab during 2006-2010 were evaluated in a historical prospective study. Analysis was performed for dosage adjustment, prescribing criteria suitability, patients' adherence and reasons for drug discontinuation...
October 1, 2012: Chest
Emmanouil Paraskakis, Nadwa Zihlif, Andrew Bush
Primary cilliary dyskinesia (PCD) is characterized by decreased levels of fractional exhaled nitric oxide (FeNO), thought to reflect low activity of airway inducible nitric oxide synthase (iNOS) levels. Alveolar NO (Calv) concentration and bronchial NO (JNO) flux can be calculated from FeNO measured at multiple exhalation flow rates. We hypothesised that whereas bronchial NO would be reduced in PCD due to reduced iNOS function, alveolar NO would reflect endothelial NOS (eNOS) function and be normal. We recorded the medical history; measured FeNO at multiple flow rates (50, 100, 200, 260 ml/sec); and performed spirometry in 24 children (aged 8-16 years)...
October 2007: Pediatric Pulmonology
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