keyword
MENU ▼
Read by QxMD icon Read
search

Pre-frontal cortex

keyword
https://www.readbyqxmd.com/read/28893928/content-specific-codes-of-parametric-vibrotactile-working-memory-in-humans
#1
Timo Torsten Schmidt, Yuan-Hao Wu, Felix Blankenburg
To understand how the brain flexibly handles mentally represented information in the absence of sensory stimulation, working memory (WM) studies have been essential. A seminal finding in monkey research is that neurons in the prefrontal cortex (PFC) retain stimulus-specific information when vibrotactile frequencies were memorized. A direct mapping between monkey studies and human fMRI research is still controversial. While oscillatory signatures, in terms of frequency dependent parametric beta-band modulation, have recently been observed in human EEG studies, the content-specificity of these representations in terms of multivariate pattern analysis has not yet been shown...
September 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28878714/modulating-the-activity-of-the-dlpfc-and-ofc-has-distinct-effects-on-risk-and-ambiguity-decision-making-a-tdcs-study
#2
Xiaolan Yang, Mei Gao, Jinchuan Shi, Hang Ye, Shu Chen
Human beings are constantly exposed to two types of uncertainty situations, risk and ambiguity. Neuroscientific studies suggest that the dorsolateral prefrontal cortex (DLPFC) and the orbital frontal cortex (OFC) play significant roles in human decision making under uncertainty. We applied the transcranial direct current stimulation (tDCS) device to modulate the activity of participants' DLPFC and OFC separately, comparing the causal relationships between people's behaviors and the activity of the corresponding brain cortex when confronted with situations of risk and ambiguity...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28868118/effects-of-left-prefrontal-transcranial-direct-current-stimulation-on-the-acquisition-of-contextual-and-cued-fear-memory
#3
Shahsanam Abbasi, Mohammad Nasehi, Hamid Reza Soleimanpour Lichaei, Mohammad-Reza Zarrindast
OBJECTIVES: Behavioral and neuroimaging studies have shown that transcranial direct current stimulation, as a non-invasive neuromodulatory technique, beyond regional effects can modify functionally interconnected remote cortical and subcortical areas. In this study, we hypothesized that the induced changes in cortical excitability following the application of cathodal or anodal tDCS over the left frontal cortex as pre-training would affect functional connectivity in resting-state circuits of fear memory and consequently could improve or disturb the acquisition of fear memory...
June 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28867993/impact-of-prefrontal-theta-burst-stimulation-on-clinical-neuropsychological-tasks
#4
Raquel Viejo-Sobera, Diego Redolar-Ripoll, Mercè Boixadós, Marc Palaus, Antoni Valero-Cabré, Elena M Marron
Theta burst stimulation (TBS) protocols hold high promise in neuropsychological rehabilitation. Nevertheless, their ability to either decrease (continuous, cTBS) or increase (intermittent, iTBS) cortical excitability in areas other than the primary motor cortex, and their consistency modulating human behaviors with clinically relevant tasks remain to be fully established. The behavioral effects of TBS over the dorsolateral prefrontal cortex (dlPFC) are particularly interesting given its involvement in working memory (WM) and executive functions (EF), often impaired following frontal brain damage...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28865755/the-relationship-between-the-superior-frontal-cortex-and-alpha-oscillation-in-a-flanker-task-simultaneous-recording-of-electroencephalogram-eeg-and-near-infrared-spectroscopy-nirs
#5
Kota Suzuki, Yasuko Okumura, Yosuke Kita, Yuhei Oi, Haruo Shinoda, Masumi Inagaki
Activity in the alpha band of the electroencephalogram (EEG) reflects functional inhibition of the cerebral cortex. The superior frontal cortex (SFC) is known to control alpha activity. Based on this relationship between SFC and alpha, we hypothesized that SFC controlled alpha mediates proactive control over interference. In this study, we examined the relationship between SFC and alpha in the flanker task by simultaneously recording EEG and near infrared spectroscopy (NIRS). Forty participants performed a flanker task with occasional (compatible 75%, incompatible 25%) and successive (incompatible 100%) conditions...
August 30, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/28855126/effects-of-epicatechin-on-frontal-cortex-dapc-and-dysbindin-of-the-mdx-mice
#6
Francisco J Estrada-Mena, Alonso Rodriguez, Patricia Mendoza-Lorenzo, Teresa Neri-Gomez, Gabriel Manjarrez-Gutierrez, Andric C Perez-Ortiz, Rosa Ordonez-Razo, Guillermo Ceballos, Francisco Villarreal, Israel Ramirez-Sanchez
INTRODUCTION: Multiple components of the dystrophin-associated protein complex (DAPC) are expressed in numerous tissues including the brain. Members of the DAPC and dysbindin are abnormally expressed in the brain of Duchenne Muscular Dystrophy (DMD) patients, which has been associated with cognitive impairments. However, little is known about the expression pattern of individual members of the DAPC in animal models of DMD and their relationship with dysbindin. METHODS: Ten mdx mice were randomly allocated into a control and intervention group [(-)-epicatechin (Epi) 1mg/kg/day for four weeks] and results compared to a wild-type mice...
August 31, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28852156/the-neural-mechanism-underpinning-balance-calibration-between-action-inhibition-and-activation-initiated-by-reward-motivation
#7
Hsin-Ju Lee, Fa-Hsuan Lin, Wen-Jui Kuo
In everyday life, it is often the case that in some situations we are motivated and want not only to speed up our actions but also to avoid mistakes-for example, ballgames. How our brain works at that moment to resolve the situations and react properly has created an active research field. Previous findings indicated that maintaining a balance between withholding and executing an action are highly dynamic and involve many executive control processes. This fMRI study was set up to investigate how motivation affects these balancing processes...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28844098/the-toxic-influence-of-dibromoacetic-acid-on-the-hippocampus-and-pre-frontal-cortex-of-rat-involvement-of-neuroinflammation-response-and-oxidative-stress
#8
Wenbo Jiang, Bai Li, Yingying Chen, Shuying Gao
Dibromoacetic acid (DBA) exsits in drinking water as a by-product of disinfection as a result of chlorination or ozonation processes. Hippocampus and pre-frontal cortex are the key structures in memory formation and weanling babies are more sensitive to environmental toxicant than adults, so this study was conducted to evaluate the potential neurotoxicity effects of DBA exposure when administered intragastrically for 4 weeks to weanling Sprague-Dawley rats, at concentration of 0, 20, 50, 125 mg/kg via the neurobehavioral and neurochemical effects...
August 26, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28838107/contralateral-anterior-interhemispheric-approach-to-medial-frontal-arteriovenous-malformations-surgical-technique-and-results
#9
Ahmad Hafez, Kunal P Raygor, Michael T Lawton
BACKGROUND: Medial frontal arteriovenous malformations (AVMs) require opening the interhemispheric fissure and are traditionally accessed through an ipsilateral anterior interhemispheric approach (IAIA). The contralateral anterior interhemispheric approach (CAIA) flips the positioning with the midline still positioned horizontally for gravity retraction, but with the AVM on the upside and the approach from the contralateral, dependent side. OBJECTIVE: To determine whether the perpendicular angle of attack associated with the IAIA converts to a more favorable parallel angle of attack with the CAIA...
August 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28831125/exploration-of-the-brain-in-rest-resting-state-functional-mri-abnormalities-in-patients-with-classic-galactosemia
#10
Britt van Erven, Bernadette M Jansma, M Estela Rubio-Gozalbo, Inge Timmers
Patients with classic galactosemia, a genetic metabolic disorder, encounter cognitive impairments, including motor (speech), language, and memory deficits. We used functional magnetic resonance imaging to evaluate spontaneous functional connectivity during rest to investigate potential abnormalities in neural networks. We characterized networks using seed-based correlation analysis in 13 adolescent patients and 13 matched controls. Results point towards alterations in several networks, including well-known resting-state networks (e...
August 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28830767/influence-of-dual-tasking-with-different-levels-of-attention-diversion-on-characteristics-of-the-movement-related-cortical-potential
#11
Susan Aliakbaryhosseinabadi, Ernest Nlandu Kamavuako, Ning Jiang, Dario Farina, Natalie Mrachacz-Kersting
Dual tasking is defined as performing two tasks concurrently and has been shown to have a significant effect on attention directed to the performance of the main task. In this study, an attention diversion task with two different levels was administered while participants had to complete a cue-based motor task consisting of foot dorsiflexion. An auditory oddball task with two levels of complexity was implemented to divert the user's attention. Electroencephalographic (EEG) recordings were made from nine single channels...
August 19, 2017: Brain Research
https://www.readbyqxmd.com/read/28821668/sensory-biased-and-multiple-demand-processing-in-human-lateral-frontal-cortex
#12
Abigail L Noyce, Nishmar Cestero, Samantha W Michalka, Barbara G Shinn-Cunningham, David C Somers
The functionality of much of human lateral frontal cortex (LFC) has been characterized as "multiple demand" (MD) as these regions appear to support a broad range of cognitive tasks. In contrast to this domain-general account, recent evidence indicates that portions of LFC are consistently selective for sensory modality. Michalka et al. (2015) reported two bilateral regions that are biased for visual attention, superior precentral sulcus (sPCS) and inferior precentral sulcus (iPCS), interleaved with two bilateral regions that are biased for auditory attention, transverse gyrus intersecting precentral sulcus (tgPCS) and caudal inferior frontal sulcus (cIFS)...
September 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28819238/effects-of-environmental-enrichment-upon-ethanol-induced-conditioned-place-preference-and-pre-frontal-bdnf-levels-in-adolescent-and-adult-mice
#13
Ricardo Marcos Pautassi, Andrea B Suárez, Lucas Barbosa Hoffmann, André Veloso Rueda, Mariana Rae, Priscila Marianno, Rosana Camarini
Environmental enrichment (EE) provides a non-pharmacological tool to alter drug-induced reward, yet its effects on ethanol-induced reward remain controversial. We analyzed adolescent vs. adult (mice) differences in the influence of EE on ethanol-induced conditioned place preference (CPP). The effects of these treatments on brain-derived neurotrophic factor (BDNF) levels in the prefrontal cortex were examined in a separate group of animals. Ethanol-induced CPP was found in adults, and it was similar in EE and in animals reared under standard housing conditions (SC)...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28808819/separating-the-idea-from-the-action-a-sloreta-study
#14
Martin Rakusa, Pierpaolo Busan, Piero Paolo Battaglini, Janez Zidar
Simple imaginary movements activate similar cortical and subcortical areas to actual movements, chiefly in the sensory-motor network. However, only a few studies also examined the imagery of more skilful movements such as reaching. Ten volunteers performed reaching movements or imagined the same movements. EEG was simultaneously recorded and analysed with sLORETA, which compared the preparation for actual and imagined reaching with respect to their baseline and between tasks. Major differences between them were found at three time intervals after target presentation, always in favour of the actual reaching condition...
August 14, 2017: Brain Topography
https://www.readbyqxmd.com/read/28806599/resting-state-functional-connectivity-of-the-anterior-striatum-and-prefrontal-cortex-predicts-reading-performance-in-school-age-children
#15
Sarael Alcauter, Liliana García-Mondragón, Zeus Gracia-Tabuenca, Martha B Moreno, Juan J Ortiz, Fernando A Barrios
The current study investigated the neural basis of reading performance in 60 school-age Spanish-speaking children, aged 6 to 9years. By using a data-driven approach and an automated matching procedure, we identified a left-lateralized resting state network that included typical language regions (Wernicke's and Broca's regions), prefrontal cortex, pre- and post-central gyri, superior and middle temporal gyri, cerebellum, and subcortical regions, and explored its relevance for reading performance (accuracy, comprehension and speed)...
August 12, 2017: Brain and Language
https://www.readbyqxmd.com/read/28795169/chronic-pain-and-chronic-stress-two-sides-of-the-same-coin
#16
Chadi G Abdallah, Paul Geha
Pain and stress share significant conceptual and physiological overlaps. Both phenomena challenge the body's homeostasis and necessitate decision-making to help animals adapt to their environment. In addition, chronic stress and chronic pain share a common behavioral model of failure to extinguish negative memories. Yet, they also have discrepancies such that the final brain endophenotype of posttraumatic stress disorder, depression, and chronic pain appears to be different among the three conditions, and the role of the hypothalamic-pituitary-adrenal axis remains unclear in the physiology of pain...
February 2017: Chronic stress
https://www.readbyqxmd.com/read/28757456/prenatal-developmental-origins-of-behavior-and-mental-health-the-influence-of-maternal-stress-in-pregnancy
#17
REVIEW
Bea R H Van den Bergh, Marion I van den Heuvel, Marius Lahti, Marijke Braeken, Susanne R de Rooij, Sonja Entringer, Dirk Hoyer, Tessa Roseboom, Katri Räikkönen, Suzanne King, Matthias Schwab
Accumulating research shows that prenatal exposure to maternal stress increases the risk for behavioral and mental health problems later in life. This review systematically analyzes the available human studies to identify harmful stressors, vulnerable periods during pregnancy, specificities in the outcome and biological correlates of the relation between maternal stress and offspring outcome. Effects of maternal stress on offspring neurodevelopment, cognitive development, negative affectivity, difficult temperament and psychiatric disorders are shown in numerous epidemiological and case-control studies...
July 28, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28747521/a-novel-18-f-labeled-kappa-opioid-receptor-antagonist-as-pet-radiotracer-synthesis-and-in-vivo-evaluation-of-18-f-ly2459989-in-non-human-primates
#18
Songye Li, Zhengxin Cai, Ming-Qiang Zheng, Daniel Holden, Mika Naganawa, Shu-Fei Lin, Jim Ropchan, David Labaree, Michael Kapinos, Teresa Lara-Jaime, Antonio Navarro, Yiyun Huang
The kappa opioid receptor (KOR) is implicated in depression, addictions, and other central nervous system (CNS) disorders and thus an important target for drug development. We have previously developed a number of (11)C-labeled PET radiotracers for KOR imaging in humans. Here we report the synthesis and evaluation of (18)F-LY2459989 as the first (18)F-labeled KOR antagonist radiotracer in non-human primates and its comparison with (11)C-LY2459989. Methods: The novel radioligand (18)F-LY2459989 was synthesized by (18)F-displacement of a nitro group or an iodonium ylide...
July 26, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28729938/abnormal-resting-state-effective-connectivity-within-the-default-mode-network-in-major-depressive-disorder-a-spectral-dynamic-causal-modeling-study
#19
Liang Li, Baojuan Li, Yuanhan Bai, Wenlei Liu, Huaning Wang, Hoi-Chung Leung, Ping Tian, Linchuan Zhang, Fan Guo, Long-Biao Cui, Hong Yin, Hongbing Lu, Qingrong Tan
INTRODUCTION: Understanding the neural basis underlying major depressive disorder (MDD) is essential for the diagnosis and treatment of this mental disorder. Aberrant activation and functional connectivity of the default mode network (DMN) have been consistently found in patients with MDD. It is not known whether effective connectivity within the DMN is altered in MDD. OBJECTS: The primary object of this study is to investigate the effective connectivity within the DMN during resting state in MDD patients before and after eight weeks of antidepressant treatment...
July 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28716966/hierarchically-organized-medial-frontal-cortex-basal-ganglia-loops-selectively-control-task-and-response-selection
#20
Franziska M Korb, Jiefeng Jiang, Joseph A King, Tobias Egner
Adaptive behavior requires context-sensitive configuration of task-sets that specify time-varying stimulus-response mappings. Intriguingly, response time costs associated with changing task-sets and motor responses are known to be strongly interactive: switch costs at the task level are small in the presence of a response-switch but large when accompanied by a response-repetition, and vice versa for response-switch costs. The reasons behind this well known interdependence between task- and response-level control processes are currently not well understood...
August 16, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
keyword
keyword
49222
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"