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https://www.readbyqxmd.com/read/28749344/giant-magnetoresistive-biosensor-array-for-detecting-magnetorelaxation
#1
Xiahan Zhou, Chih-Cheng Huang, Drew A Hall
In this paper, a time-domain magnetorelaxometry biosensing scheme is presented using giant magnetoresistive (GMR) sensors to measure the fast relaxation response of superparamagnetic magnetic nanoparticles (MNPs) in a pulsed magnetic field. The system consists of an 8 × 10 GMR sensor array, a Helmholtz coil, an electromagnet driver, and an integrator-based analog front-end needed to capture the fast relaxation dynamics of MNPs. A custom designed electromagnet driver and Helmholtz coil improve the switch-off speed to >5 Oe/μs, limiting the dead zone time to <10 μs, and thus enables the system to monitor fast relaxation processes of 30 nm MNPs...
August 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28749272/ketamine-medetomidine-and-ketamine-medetomidine-midazolam-anesthesia-in-captive-cheetahs-acinonyx-jubatus-comparison-of-blood-pressure-and-kidney-blood-flow
#2
Julia Stagegaard, Arne Hørlyck, Helle B Hydeskov, Mads F Bertelsen
Six clinically healthy captive cheetahs ( Acinonyx jubatus ) were anesthetized twice using two different drug combinations to investigate if blood pressure and kidney blood flow are affected by medetomidine dosage. Protocol KM (2.0 mg/kg ketamine and 0.05 mg/kg medetomidine) was compared with protocol KMM (2.0 mg/kg ketamine, 0.02 mg/kg medetomidine, and 0.1 mg/kg midazolam). Heart rate (HR), respiratory rate (RR), body temperature, end-tidal carbon dioxide pressure (ETCO2), and anesthetic depth were monitored every 10 min...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749031/unraveling-proximate-cues-of-mass-flowering-in-the-tropical-forests-of-southeast-asia-from-gene-expression-analyses
#3
Suat Hui Yeoh, Akiko Satake, Shinya Numata, Tomoaki Ichie, Soon Leong Lee, Norlia Basherudin, Norwati Muhammad, Toshiaki Kondo, Tatsuya Otani, Mazlan Hashim, Naoki Tani
Elucidating the physiological mechanisms of the irregular yet concerted flowering rhythm of mass flowering tree species in the tropics requires long term monitoring of flowering phenology, exogenous and endogenous environmental factors, as well as identifying interactions and dependencies among these factors. To investigate the proximate factors for floral initiation of mast seeding trees in the tropics, we monitored the expression dynamics of two key flowering genes, meteorological conditions and endogenous resources over two flowering events of Shorea curtisii and Shorea leprosula in the Malay Peninsula...
July 27, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28748371/acute-effects-of-heated-resistance-exercise-in-female-and-male-power-athletes
#4
Julia R Casadio, Adam G Storey, Fabrice Merien, Andrew E Kilding, James D Cotter, Paul B Laursen
PURPOSE: To determine the effects of heated resistance exercise on thermal strain, neuromuscular function and hormonal responses in power athletes. METHODS: Sixteen (n = 8 female; 8 male) highly trained power athletes completed a combined strength and power resistance exercise session in hot (HOT ~30 °C) and temperate (CON ~20 °C) conditions. Human growth hormone (hGH), cortisol and testosterone concentrations in plasma, peak power (counter-movement jump, CMJ) and peak force (isometric mid-thigh pull) were measured before and after each training session; thermoregulatory responses were monitored during training...
July 26, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28748092/a-focused-ultrasound-treatment-system-for-moving-targets-part-i-generic-system-design-and-in-silico-first-stage-evaluation
#5
Michael Schwenke, Jan Strehlow, Daniel Demedts, Sabrina Haase, Diego Barrios Romero, Sven Rothlübbers, Caroline von Dresky, Stephan Zidowitz, Joachim Georgii, Senay Mihcin, Mario Bezzi, Christine Tanner, Giora Sat, Yoav Levy, Jürgen Jenne, Matthias Günther, Andreas Melzer, Tobias Preusser
BACKGROUND: Focused ultrasound (FUS) is entering clinical routine as a treatment option. Currently, no clinically available FUS treatment system features automated respiratory motion compensation. The required quality standards make developing such a system challenging. METHODS: A novel FUS treatment system with motion compensation is described, developed with the goal of clinical use. The system comprises a clinically available MR device and FUS transducer system...
2017: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/28746792/rate-of-warming-affects-temperature-sensitivity-of-anaerobic-peat-decomposition-and-greenhouse-gas-production
#6
Debjani Sihi, Patrick W Inglett, Stefan Gerber, Kanika Sharma Inglett
Temperature sensitivity of anaerobic carbon mineralization in wetlands remains poorly represented in most climate models and is especially unconstrained for warmer subtropical and tropical systems which account for a large proportion of global methane emissions. Several studies of experimental warming have documented thermal acclimation of soil respiration involving adjustments in microbial physiology or carbon use efficiency (CUE), with an initial decline in CUE with warming followed by a partial recovery in CUE at a later stage...
July 26, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28746770/unexpected-high-genetic-diversity-in-small-populations-suggests-maintenance-by-associative-overdominance
#7
Mads F Schou, Volker Loeschcke, Jesper Bechsgaard, Christian Schlötterer, Torsten N Kristensen
The effective population size (Ne ) is a central factor in determining maintenance of genetic variation. The neutral theory predicts that loss of variation depends on Ne , with less genetic drift in larger populations. We monitored genetic drift in 42 Drosophila melanogaster populations of different adult census population sizes (10, 50 or 500) using pooled RAD sequencing. In small populations, variation was lost at a substantially lower rate than expected. This observation was consistent across two ecological relevant thermal regimes, one stable and one with a stressful increase in temperature across generations...
July 26, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28746411/selection-and-validation-of-reference-genes-for-quantitative-real-time-pcr-analysis-under-different-experimental-conditions-in-the-leafminer-liriomyza-trifolii-diptera-agromyzidae
#8
Ya-Wen Chang, Jing-Yun Chen, Ming-Xing Lu, Yuan Gao, Zi-Hua Tian, Wei-Rong Gong, Wei Zhu, Yu-Zhou Du
Liriomyza trifolii is a highly-invasive leafmining insect that causes significant damage to vegetables and horticultural crops worldwide. Relatively few studies have quantified gene expression in L. trifolii using real-time quantitative PCR (RT-qPCR), which is a reliable and sensitive technique for measuring gene expression. RT-qPCR requires the selection of reference genes to normalize gene expression data and control for internal differences between samples. In this study, nine housekeeping genes from L. trifolii were selected for their suitability in normalizing gene expression using geNorm, Normfinder, BestKeeper, the ΔCt method and RefFinder...
2017: PloS One
https://www.readbyqxmd.com/read/28746410/environmental-factors-influencing-the-spatio-temporal-distribution-of-carybdea-marsupialis-lineo-1978-cubozoa-in-south-western-mediterranean-coasts
#9
Antonio Canepa, Verónica Fuentes, Mar Bosch-Belmar, Melissa Acevedo, Kilian Toledo-Guedes, Antonio Ortiz, Elia Durá, César Bordehore, Josep-Maria Gili
Jellyfish blooms cause important ecological and socio-economic problems. Among jellyfish, cubozoans are infamous for their painful, sometimes deadly, stings and are a major public concern in tropical to subtropical areas; however, there is little information about the possible causes of their outbreaks. After a bloom of the cubomedusa Carybdea marsupialis (Carybdeidae) along the coast of Denia (SW Mediterranean, Spain) in 2008 with negative consequences for local tourism, the necessity to understand the ecological restrictions on medusae abundance was evident...
2017: PloS One
https://www.readbyqxmd.com/read/28745913/a-dry-method-for-preserving-tear-protein-samples
#10
Weiwei Qin, Chan Zhao, Linpei Zhang, Ting Wang, Youhe Gao
Tears covering the ocular surface are important biofluids containing thousands of molecules, including proteins, lipids, metabolites, nucleic acids, and electrolytes. Tears are valuable resources for biomarker research of ocular and even systemic diseases. For application in biomarker studies, tear samples should ideally be stored using a simple, lowcost, and efficient method along with the patient's medical records. For this purpose, we developed a novel Schirmer's strip-based dry method that allows for storage of tear samples in vacuum bags at room temperature...
July 26, 2017: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/28745848/optimizing-survival-outcomes-for-adult-patients-with-nontraumatic-cardiac-arrest-digest
#11
Julianna Jung, Milana Zaurova
Patient survival after cardiac arrest can be improved significantly with prompt and effective resuscitative care. This systematic review analyzes the basic life support factors that improve survival outcome, including chest compression technique and rapid defibrillation of shockable rhythms. For patients who are successfully resuscitated, comprehensive postresuscitation care is essential. Targeted temperature management is recommended for all patients who remain comatose, in addition to careful monitoring of oxygenation, hemodynamics, and cardiac rhythm...
October 22, 2016: Emergency Medicine Practice
https://www.readbyqxmd.com/read/28745755/molecular-engineering-of-lanthanide-ion-chelating-phospholipids-generating-assemblies-with-a-switched-magnetic-susceptibility
#12
Stéphane Isabettini, Sarah Massabni, Arnel Hodzic, Dzana Durovic, Joachim Kohlbrecher, Takashi Ishikawa, Peter Fischer, Erich J Windhab, Peter Walde, Simon Kuster
Lanthanide ion (Ln(3+)) chelating amphiphiles are powerful molecules for tailoring the magnetic response of polymolecular assemblies. Mixtures of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and 1,2-dimyristoyl-sn-glycero-3-phospho-ethanolamine-diethylene triaminepentaacetate (DMPE-DTPA) complexed to Ln(3+) deliver highly magnetically responsive bicelles. Their magnetic properties are readily tuned by changing the bicellar size or the magnetic susceptibility Δχ of the bilayer lipids. The former technique is intrinsically bound to the region of the phase diagram guarantying the formation of bicelles...
July 26, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28744949/identification-of-a-new-mineralized-tissue-in-the-notochord-of-reared-siberian-sturgeon-acipenser-baerii
#13
Amandine Leprévost, Thierry Azaïs, Michael Trichet, Jean-Yves Sire
In a study aiming to improve knowledge on the mineralization of the axial skeleton in reared Siberian sturgeon (Acipenser baerii Brandt, 1869), we discovered a new mineralized tissue within the notochord. To our knowledge, such a structure has never been reported in any vertebrate species with the exception of the pathological mineralization of the notochord remains in degenerative intervertebral disks of mammals. Here, we describe this enigmatic tissue using X-ray microtomography, histological analyses and solid state NMR-spectroscopy...
July 25, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28743152/-prevention-of-perioperative-hypothermia-guidelines-for-daily-clinical-practice
#14
Timo Iden, Jan Höcker
Inadvertent perioperative hypothermia (body core temperature < 36 °C) is a serious complication leading to increased rates of wound infection, higher blood loss associated with increased transfusion requirements as well as patient dissatisfaction among others. Body core temperature is a vital parameter and needs constant monitoring just like heart rate, blood pressure and arterial oxygen saturation. Patient-, anesthesia-, surgery- and environment-related risk factors were identified for occurring perioperative hypothermia...
July 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/28743027/impact-of-heat-stress-on-estrus-expression-and-follicle-size-in-estrus-under-field-conditions-in-dairy-cows
#15
L K Schüller, I Michaelis, W Heuwieser
The objective of this study was to investigate the impact of heat stress on the expression of estrus signs and follicular diameter at the day of estrus in dairy cows under farm conditions. Cows reported in estrus (i.e., by an automated activity monitoring system or by the herd manager) were examined by a veterinarian. Uterine contractility and the largest diameter of all ovarian structures was determined by transrectal palpation and ultrasonography, respectively. The amount of estrus discharge, mounting traces and the color of the vaginal mucosa were determined in an external examination and scored on 3-point scales...
July 10, 2017: Theriogenology
https://www.readbyqxmd.com/read/28742423/chemical-immobilization-of-free-ranging-yellow-armadillos-euphractus-sexcinctus-for-implantation-of-intra-abdominal-transmitters
#16
Vinicius Peron de Oliveira Gasparotto, Nina Attias, Flávia Regina Miranda, Grazielle Cristina Garcia Soresini, Ariel da Costa Canena, Guilherme Mourão
Free-ranging yellow armadillos (Euphractus sexcinctus) from the Brazilian Pantanal were captured for surgical implantation of intra-abdominal radio transmitters. During March 2014, 11 animals were chemically immobilized with a combination of intramuscular ketamine hydrochloride, xylazine hydrochloride, midazolam maleate, and atropine sulfate. The mean induction time and initial heart rate in males was higher than in females. The sex of armadillos did not affect the respiratory rate, which increased from the beginning to end of the monitoring time...
July 25, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28742232/altering-the-coordination-of-iron-porphyrins-by-ionic-liquid-nanodomains-in-mixed-solvent-systems
#17
Abderrahman Atifi, Michael Ryan
The solvent environment around iron porphyrin complexes was examined using mixed molecular/RTIL (room temperature ionic liquid) solutions. The formation of nanodomains in these solutions provides different solvation environments for substrates that could have significant impact on their chemical reactivity. Iron porphyrins (Fe(P)), whose properties are sensitive to solvent and ligation changes, were used to probe the molecular/RTIL environment. The addition of RTILs to molecular solvents shifted the redox potentials to more positive values...
July 25, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28741643/self-reference-plasmonic-sensors-based-on-double-fano-resonances
#18
Yujia Wang, Chengwei Sun, Hongyun Li, Qihuang Gong, Jianjun Chen
High-sensitivity plasmonic refractive index sensors show great applications in the areas of biomedical diagnostics, healthcare, food safety, environmental monitoring, homeland security, and chemical reactions. However, the unstable and complicated environments considerably limit their practical applications. By employing the independent double Fano resonances in a simple metallic grating, we experimentally demonstrate a self-reference plasmonic sensor, which significantly reduces the error contributions of the light intensity fluctuations in the long-distance propagation and local temperature variations at the metallic grating, and the detection accuracy is guaranteed...
July 25, 2017: Nanoscale
https://www.readbyqxmd.com/read/28741353/efficient-heterostructures-of-ag-cuo-batio3-for-low-temperature-co2-gas-detection-assessing-the-role-of-nanointerfaces-during-sensing-by-operando-drifts-technique
#19
Shravanti Joshi, Samuel J Ippolito, Selvakannan R Periasamy, Ylias M Sabri, Manorama V Sunkara
Tetragonal BaTiO3 spheroids synthesized by a facile hydrothermal route using Tween 80 were observed to be polydispersed with a diameter in the range ~15 to 75 nm. Thereon, BaTiO3 spheroids were decorated with different percentages of Ag@CuO by wet impregnation and their affinity towards CO2 gas when employed as sensitive layers in a microsensor was investigated. The results revealed that the metal-nanocomposite based sensor had an exceptional selectivity and sensitivity toward CO2 gas (6-fold higher response) with appreciable response and recovery times (<10 s), high repeatability (98%) and accuracy (96%) at a low operating temperature of 120oC, when compared with that of pure BaTiO3 and CuO...
July 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28741242/the-weakening-effect-of-soluble-epoxide-hydrolase-inhibitor-auda-on-febrile-response-to-lipopolysaccharide-and-turpentine-in-rat
#20
Jakub Piotrowski, Tomasz Jędrzejewski, Małgorzata Pawlikowska, Agata Joanna Pacuła, Jacek Ścianowski, Wiesław Kozak
A still growing body of evidence suggests the importance of epoxyeicosatrienoic acids (EETs) in the regulation of inflammatory response; therefore, drugs that stabilize their levels by targeting the soluble epoxide hydrolase (sEH), an enzyme responsible for their metabolism, are currently under investigation. The effect of sEH inhibitors on molecular components of fever mechanism, i.e., on synthesis of pro-inflammatory cytokines or prostaglandins, has been repeatedly proven; however, the hypothesis that sEH inhibitors affect febrile response has never been tested...
July 24, 2017: Journal of Physiology and Biochemistry
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