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https://www.readbyqxmd.com/read/28530769/beneficial-effects-of-garlic-allium-sativum-oil-in-experimental-corrosive-esophageal-burns-effects-of-garlic-oil-in-esophageal-burns
#1
Ceren Şen Tanrıkulu, Yusuf Tanrikulu, Fahriye Kılınç, Burak Bahadır, Murat Can, Füruzan Köktürk
BACKGROUND: Corrosive esophageal burns, particularly common in developing countries, lead to different problems in different age groups. The ingestion of corrosive substances can cause such problems as stricture of the esophagus, to acute perforation, and even death. Because stricture formation is related to the severity of the initial injury, the prevention of stricture constitutes a main goal of treatment. The aim of this study was to investigate the protective and anti-inflammatory effects of garlic (Allium sativum) oil in corrosive esophageal burn...
May 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28512048/combined-hyperactive-dysfunction-syndrome-of-the-cranial-nerves-a-retrospective-systematic-study-of-clinical-characteristics-in-44-patients
#2
Jingwei Cao, Jie Jiao, Zhenhui Du, Wenzhe Xu, Bin Sun, Feng Li, Yuguang Liu
BACKGROUND: Combined hyperactive dysfunction syndrome (HDS) is defined as the combination symptoms arising from overactivity in cranial nerves specifically, trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia (GPN) without an obvious explanatory structural lesion. The study aims to retrospectively analyze the clinical characteristics of combined HDS treated with microvascular decompression (MVD) in a single institution. METHODS: A total of 1450 patients with HDS were treated with MVD in our department during a 10-year period, among which 44 cases of combined HDS were identified...
May 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28508833/radiation-induced-non-targeted-effect-in-vivo-evaluation-of-cyclooygenase-2-and-endothelin-1-gene-expression-in-rat-heart-tissues
#3
Reza Fardid, Masoud Najafi, Ashkan Salajegheh, Elahe Kazemi, Abolhasan Rezaeyan
AIM: In this study, we investigated expression levels of cyclooxygenase-2 (COX-2) and endothelin-1 (ET-1) genes after pelvis and heart irradiation in a rat model. These factors are involved in heart diseases (HDs). MATERIALS AND METHODS: We used seven groups, including two groups of pelvic irradiation, two groups of whole body irradiation, two groups of heart irradiation, and one control nonirradiated group. Pelvis irradiations were conducted at a 2 cm × 2 cm in the pelvis area...
January 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28499448/comparison-of-demographic-characteristics-and-psychiatric-comorbidity-among-methamphetamine-heroin-and-methamphetamine-heroin-co-dependent-males-in-hunan-china
#4
Huixi Dong, Mei Yang, Liang Liu, Chenxi Zhang, Mengqi Liu, Yidong Shen, Huanzhong Liu, Wei Hao
BACKGROUND: There is little research of psychiatric comorbidity differences among people with different types of drug dependence in Chinese population. We explored demographic and comorbid psychiatric differences among methamphetamine- dependent males (MDs), heroin-dependent males (HDs) and methamphetamine and heroin co-dependent males (M/HDs) in Hunan province, China. METHODS: A cross-sectional, structured and clinical interview method was used to examine differences in DSM-IV-TR Axis I Disorders among 346 MDs, 698 HDs and 247 M/HDs from three compulsory rehabilitation centers and two voluntary rehabilitation centers in Hunan...
May 12, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28497420/the-role-of-high-airway-pressure-and-dynamic-strain-on-ventilator-induced-lung-injury-in-a-heterogeneous-acute-lung-injury-model
#5
Sumeet V Jain, Michaela Kollisch-Singule, Joshua Satalin, Quinn Searles, Luke Dombert, Osama Abdel-Razek, Natesh Yepuri, Antony Leonard, Angelika Gruessner, Penny Andrews, Fabeha Fazal, Qinghe Meng, Guirong Wang, Louis A Gatto, Nader M Habashi, Gary F Nieman
BACKGROUND: Acute respiratory distress syndrome causes a heterogeneous lung injury with normal and acutely injured lung tissue in the same lung. Improperly adjusted mechanical ventilation can exacerbate ARDS causing a secondary ventilator-induced lung injury (VILI). We hypothesized that a peak airway pressure of 40 cmH2O (static strain) alone would not cause additional injury in either the normal or acutely injured lung tissue unless combined with high tidal volume (dynamic strain). METHODS: Pigs were anesthetized, and heterogeneous acute lung injury (ALI) was created by Tween instillation via a bronchoscope to both diaphragmatic lung lobes...
December 2017: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/28479843/usp-800-adds-significant-safety-standards-facility-upgrades-needed-to-protect-employees-from-hazardous-drugs
#6
Bruce E Beans
The new USP standard for handling hazardous drugs (HDs) will require millions of dollars in capital outlays for facility and equipment upgrades and also requires in-depth assessments of each HD that facilities handle, significant workflow and work practice changes, and thorough staff training.
May 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28467608/gallium-modified-husy-zeolite-as-an-effective-cosupport-for-nimo-hydrodesulfurization-catalyst-and-the-catalyst-s-high-isomerization-selectivity
#7
Wenwu Zhou, Yasong Zhou, Qiang Wei, Lin Du, Sijia Ding, Shujiao Jiang, Yanan Zhang, Qing Zhang
The effects of metal-modified acidic cosupports on the HDS activity and isomerization selectivity of highly refractory organosulfur compounds such as 4,6-dimethyldibenzothiophene have been investigated. Y crystals with high Si/Al ratios and small crystallite sizes were successfully synthesized by a new hydrothermal synthesis approach. The synthesized Y crystals were ion-exchanged and stabilized. The prepared samples were then modified with different gallium contents using a impregnation method to adjust their acidity properties, and these modified samples were used as cosupports for NiMo sulfide hydrodesulfurization (HDS) catalysts...
May 3, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28454692/maternal-vascular-malperfusion-of-the-placental-bed-associated-with-hypertensive-disorders-in-the-boston-birth-cohort
#8
Blandine Bustamante Helfrich, Nymisha Chilukuri, Huan He, Sandra R Cerda, Xiumei Hong, Guoying Wang, Colleen Pearson, Irina Burd, Xiaobin Wang
INTRODUCTION: The associations of maternal conditions, before or during pregnancy, with placental lesions have not been adequately studied in populations. METHODS: In the Boston Birth Cohort, we evaluated associations between three maternal medical conditions (hypertensive disorders [HDs], gestational/pre-gestational diabetes and obesity), and placental histological findings, using a standardized classification system proposed by the Amsterdam Placental Workshop Group...
April 2017: Placenta
https://www.readbyqxmd.com/read/28436344/inattention-tests-for-delirium
#9
Paul Regal
Voyer and colleagues (2016) report an interesting and important comparison of ten attention/concentration tests for DSM-5 delirium. I have a number of questions and comments as follows: (1) What training did the research assistants have? DSM-5 diagnosis is generally regarded as a decision by medical specialists. When the person has prior dementia, identifying delirium is a high-level medical skill. Behavioral and psychological symptoms of dementia can closely mimic delirium unless the examiner focuses on behavioral triggers and the speed of cognitive decline...
April 24, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28422138/abnormal-resting-state-functional-connectivity-in-the-orbitofrontal-cortex-of-heroin-users-and-its-relationship-with-anxiety-a-pilot-fnirs-study
#10
Hada Fong-Ha Ieong, Zhen Yuan
Drug addiction is widely linked to the orbitofrontal cortex (OFC), which is essential for regulating reward-related behaviors, emotional responses, and anxiety. Over the past two decades, neuroimaging has provided significant contributions revealing functional and structural alternations in the brains of drug addicts. However, the underlying neural mechanism in the OFC and its correlates with drug addiction and anxiety still require further elucidation. We first presented a pilot investigation to examine local networks in OFC regions through resting-state functional connectivity (rsFC) using functional near-infrared spectroscopy (fNIRS) from eight abstinent addicts in a heroin-dependent group (HD) and seven subjects in a control group (CG)...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28415004/types-of-household-humidifier-disinfectant-and-associated-risk-of-lung-injury-hdli-in-south-korea
#11
Dong-Uk Park, Seung-Hun Ryu, Heung-Kyu Lim, Sun-Kyung Kim, Ye-Yong Choi, Jong-Ju Ahn, Eun Lee, Sang-Bum Hong, Kyung-Hyun Do, Jae-Lim Cho, Mun-Joo Bae, Dong-Chun Shin, Do-Myung Paek, Soo-Jong Hong
From 2002 through 2015, hundreds of people died of fatal lung injuries associated with the use of humidifier disinfectants (HDs) in Korea. Several chemical disinfectants used for household humidifiers were later clinically confirmed to cause HD-associated lung injury (HDLI). The aim of this study is to evaluate the registered lung disease cases and to compare the distribution of HDLI patients, including deaths, by HD use characteristics including types of HD and HD brands categorized by age group. A total of 530 registered were clinically examined through two rounds of investigations conducted from July 2013 until April 2015...
April 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28369686/on-demand-tuned-hazard-free-elastomeric-composites-a-green-approach
#12
Partheban Manoharan, Narayan Chandra Das, Kinsuk Naskar
Rising ecological concerns and depletion of the potentially harmful environmental impacts caused by rubber products, are of prime importance in the industry. Therefore, implementation of sustainable greener materials is required to minimize the detrimental influences. In this research, we investigated the beneficial influence of naturally derived bio-resin towards the effects of association with Zinc Oxide Nanoparticles in highly dispersible silica (HDS) reinforced Natural rubber (NR)/Epoxidized Natural Rubber (ENR) based composites...
March 31, 2017: Biopolymers
https://www.readbyqxmd.com/read/28350097/identification-of-novel-cancer-fusion-genes-using-chromosome-breakpoint-screening
#13
Kate Hua, Chin-Hui Lin, Ya-Lun Chen, Chi-Hung Lin, Yueh-Hsin Ping, Yuh-Shan Jou, Chian-Feng Chen
Gene fusion due to rearrangement or translocation of chromosomes is a powerful mutational mechanism during tumorigenesis. Several new high-resolution technologies have recently been developed to evaluate large numbers of small aberrations as candidate loci for fusion gene screening. In our previous whole-genome screening study using 500K SNP arrays, we identified more than 700 homozygous deletions (HDs) and amplicons in 23 cancer cell lines. To explore novel fusion genes in cancer, we established stringent criteria for defining HD and amplicon breakpoints...
April 2017: Oncology Reports
https://www.readbyqxmd.com/read/28344060/basal-cd34-cell-count-predicts-peripheral-blood-stem-cell-mobilization-in-healthy-donors-after-administration-of-granulocyte-colony-stimulating-factor-a-longitudinal-prospective-observational-single-center-cohort-study
#14
Massimo Martino, Mercedes Gori, Annalisa Pitino, Massimo Gentile, Antonia Dattola, Antonella Pontari, Ernesto Vigna, Tiziana Moscato, Anna Grazia Recchia, Santina Barilla', Giovanni Tripepi, Fortunato Morabito
A longitudinal, prospective, observational, single-center, cohort study on healthy donors (HDs) was designed to identify predictors of CD34(+) cells on day 5 with emphasis on the predictive value of the basal CD34(+) cell count. As potential predictors of mobilization, age, sex, body weight, height, blood volume as well as white blood cell count, peripheral blood (PB) mononuclear cells, platelet count, hematocrit, and hemoglobin levels were considered. Two different evaluations of CD34(+) cell counts were determined for each donor: baseline (before granulocyte colony-stimulating factor [G-CSF] administration) and in PB after G-CSF administration on the morning of the fifth day (day 5)...
March 24, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28315550/hazardous-drugs-and-usp-800-implications-for-nurses
#15
Seth Eisenberg
BACKGROUND: Although guidelines for the safe handling of hazardous drugs (HDs) have existed for several decades, they have not been enforceable by state or federal agencies. USP <800>, the latest chapter issued by the U.S. Pharmacopeial Convention, expands on existing guidelines and provides detailed information on compounding and administration. Unlike current guidelines, USP <800> will be enforced by each state's board of pharmacy or their delegated agency.
. OBJECTIVES: This article provides a brief overview of the dangers associated with HDs and the implications of USP <800> for nurses...
April 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28280882/alcohol-induced-performance-impairment-a-5-year-re-examination-study-in-heavy-and-light-drinkers
#16
Ty Brumback, Dingcai Cao, Patrick McNamara, Andrea King
BACKGROUND: The theory of behavioral tolerance to alcohol posits that greater experience with drinking to intoxication leads to less impaired cognitive and psychomotor performance. However, the degree to which behavioral tolerance develops or changes over time in adults due to repeated heavy alcohol drinking has not been clearly demonstrated. METHOD: We examined data from the first 6 years of the Chicago Social Drinking Project to test whether chronic heavy drinkers (HDs; n = 86) and light drinkers (LDs; n = 69) exhibit behavioral tolerance or changes in perceived impairment at two testing phases in early adulthood...
March 9, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28273570/novel-geochemistry-inspired-method-for-the-deep-removal-of-vanadium-from-molybdate-solution
#17
Jialiang Zhang, Yuping Deng, Qiuyue Zhou, Peixin Qin, Yubo Liu, Chengyan Wang
Separation of vanadium from molybdates is an essential task for processing the leaching solution of hazardous spent hydrodesulphurization (HDS) catalyst. In this study, the difference in the main naturally occurring mineral forms of Mo and V inspired us to develop a method for the deep removal of V from molybdate solution using Fe3O4 as an adsorbent. First, the adsorbent was synthesized with coprecipitation method, and then it was characterized by XRD, TEM, and VSM. The synthesized material consisted of pure Fe3O4 nanoparticles that exhibited paramagnetic property, with a saturated magnetization of 68...
February 28, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28269765/central-review-of-amyloid-related-imaging-abnormalities-in-two-phase-iii-clinical-trials-of-bapineuzumab-in-mild-to-moderate-alzheimer-s-disease-patients
#18
Nzeera Ketter, H Robert Brashear, Jennifer Bogert, Jianing Di, Yves Miaux, Achim Gass, Derk D Purcell, Frederik Barkhof, H Michael Arrighi
BACKGROUND: Amyloid-related imaging abnormalities (ARIA) consist of ARIA-E (with effusion or edema) and ARIA-H (hemosiderin deposits [HDs]). OBJECTIVES: To address accurate ascertainment of ARIA identification, a final magnetic resonance imaging (MRI) reading was performed on patients with mild-to-moderate Alzheimer's disease randomized to bapineuzumab IV or placebo during two Phase III trials (APOE ɛ4 allele carriers or noncarriers). METHODS: Final MRI central review consisted of a systematic sequential locked, adjudicated read in 1,331 APOE ɛ4 noncarriers and 1,121 carriers by independent neuroradiologists...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28245863/epstein-barr-virus-lytic-infection-promotes-activation-of-toll-like-receptor-8-innate-immune-response-in-systemic-sclerosis-monocytes
#19
Antonella Farina, Giovanna Peruzzi, Valentina Lacconi, Stefania Lenna, Silvia Quarta, Edoardo Rosato, Anna Rita Vestri, Michael York, David H Dreyfus, Alberto Faggioni, Stefania Morrone, Maria Trojanowska, G Alessandra Farina
BACKGROUND: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon (IFN)-regulatory genes and inflammatory cytokines, suggesting dysregulation of the innate immune response in autoimmunity. In this study, we investigated whether the lytic form of Epstein-Barr virus (EBV) infection (infectious EBV) is present in scleroderma monocytes and contributes to their activation in SSc. METHODS: Monocytes were isolated from peripheral blood mononuclear cells (PBMCs) depleted of the CD19+ cell fraction, using CD14/CD16 negative-depletion...
February 28, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28219592/urgent-liver-transplantation-for-dietary-supplements-an-under-recognized-problem
#20
MULTICENTER STUDY
L L Wong, L Lacar, M Roytman, S L Orloff
BACKGROUND: The recent outbreak of acute liver failure caused by herbal/dietary supplements (HDS) in Hawaii prompted evaluation of those patients who underwent emergency liver transplantation (LT) for HDS in the United States. METHODS: We queried the Scientific Registry of Transplant Recipients (2003-2015) to identify patients who underwent urgent LT for acute hepatic necrosis (AHN) and identified those with HDS use. This group of patients was then characterized...
March 2017: Transplantation Proceedings
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