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Emily Lauren Graczyk, Benoit Delhaye, Matthew A Schiefer, Sliman J Bensmaia, Dustin J Tyler
Sensory systems adapt their sensitivity to ambient stimulation levels to improve their responsiveness to changes in stimulation. The sense of touch is also subject to adaptation, as evidenced by the desensitization produced by prolonged vibratory stimulation of the skin. Electrical stimulation of nerves elicits tactile sensations that can convey feedback for bionic limbs. In this study, we investigate whether artificial touch is also subject to adaptation, despite the fact that the peripheral mechanotransducers are bypassed...
March 19, 2018: Journal of Neural Engineering
Wei Qian, Xiaodong Hu, Weifeng He, Rixing Zhan, Menglong Liu, Daijun Zhou, Yong Huang, Xiaohong Hu, Zhanhua Wang, Guoxia Fei, Jun Wu, Malcolm Xing, Hesheng Xia, Gaoxing Luo
Toward fabricating a novel multifunctional wound dressing material, we incorporated a series of contents of reduced graphene oxide (rGO) sheets into polydimethylsiloxane (PDMS) matrix to prepare the rGO-PDMS composite membrane and be used for wound dressing. The pore structure, dispersion of rGO, physical properties, water vapor transmission rate (WVTR), cytotoxicity and antibacterial activity were studied. Finally, the effect of the rGO-PDMS composite membrane on wound healing was investigated on a murine full-thickness skin wound model...
March 12, 2018: Colloids and Surfaces. B, Biointerfaces
Yuval Elani, Tatiana Trantidou, Douglas Wylie, Linda Dekker, Karen Polizzi, Robert V Law, Oscar Ces
There is increasing interest in constructing artificial cells by functionalising lipid vesicles with biological and synthetic machinery. Due to their reduced complexity and lack of evolved biochemical pathways, the capabilities of artificial cells are limited in comparison to their biological counterparts. We show that encapsulating living cells in vesicles provides a means for artificial cells to leverage cellular biochemistry, with the encapsulated cells serving organelle-like functions as living modules inside a larger synthetic cell assembly...
March 14, 2018: Scientific Reports
Tianzhao Bu, Tianxiao Xiao, Zhiwei Yang, Guoxu Liu, Xianpeng Fu, Jinhui Nie, Tong Guo, Yaokun Pang, Junqing Zhao, Fengben Xi, Chi Zhang, Zhong Lin Wang
Smart skin is expected to be stretchable and tactile for bionic robots as the medium with the ambient environment. Here, a stretchable triboelectric-photonic smart skin (STPS) is reported that enables multidimensional tactile and gesture sensing for a robotic hand. With a grating-structured metal film as the bioinspired skin stripe, the STPS exhibits a tunable aggregation-induced emission in a lateral tensile range of 0-160%. Moreover, the STPS can be used as a triboelectric nanogenerator for vertical pressure sensing with a maximum sensitivity of 34 mV Pa-1 ...
March 13, 2018: Advanced Materials
G Zhou, K P Wang, H W Liu, L Wang, X F Xiao, D D Dou, Y B Fan
Owing to low bearing capacity and efficiency, traditional filters or adsorbents for removal of contaminants like crystal violet (CV) dye required frequent replacement. Besides, the combination of three-dimensional (3D) printing and bionics could break the constraints of traditional configuration. In this study, a novel depth-type hybrid polylactic acid (PLA)@graphene oxide (GO)/chitosan (CS) sponge filter with bionic fish-mouth structure was prepared and fabricated, assisted by 3D printing and double freeze-drying technology, according to the theories of vertical cross-step filtration and swirling flow...
March 9, 2018: International Journal of Biological Macromolecules
Leng-Duei Koh, Jingjie Yeo, Yeong Yuh Lee, Qunya Ong, Mingyong Han, Benjamin C-K Tee
The present review will introduce the basic concepts of silk-based electronics/optoelectronics including the latest technological advances on the use of silk fibroin in combination with other functional components, with an emphasis on improving the performance of next-generation silk-based materials. It also highlights the patterning of silk fibroin to produce micro/nano-scale features, as well as the functionalization of silk fibroin to impart antimicrobial (i.e. antibacterial) properties. Silk-based bioelectronics have great potential for advanced or futuristic bio-applications including e-skins, e-bandages, biosensors, wearable displays, implantable devices, artificial muscles, etc...
May 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
Lin Wang, Yingze Zhang, Zhaohui Song, Hengrui Chang, Ye Tian, Fei Zhang
PURPOSE: To describe and evaluate the novel method of using elastic bionic fixation device in treating the distal tibiofibular syndesmosis (DTS) injury. METHODS: From June 2013 to January 2014, 17 subjects with ankle fractures combined with DTS separation were treated by the elastic bionic fixation device. The syndesmotic parameters, healing, functional scores, and possible complications were recorded. RESULTS: All patients had a mean follow-up of 23...
March 9, 2018: International Orthopaedics
Zhihong Zhang, Xiaoyang Wang, Jin Tong, Carr Stephen
A highly efficient soil-burrowing dung beetle possesses an intricate outer contour curve on its foreleg end-tooth. This study was carried out based on evidence that this special outer contour curve has the potential of reducing soil penetration resistance and could enhance soil-burrowing efficiency. A toothed wheel is a typical agricultural implement for soil imprinting, to increase its working efficiency; the approach of the bionic geometrical structure was utilized to optimize the innovative shape of imprinting toothed wheel...
2018: Applied Bionics and Biomechanics
Hui Pan, Da-Wei Wang, Qingfa Peng, Jun Ma, Xin Meng, Yaopeng Zhang, Yuning Ma, Shenmin Zhu, Di Zhang
The miniaturization of portable electronic devices has fueled the development of microsupercapacitors that hold great potential to complement or even to replace microbatteries and electrolytic capacitors. In spite of recent development taking advantage of printing and lithography, it remains a great challenge to attain high energy density without sacrificing power density. Herein, a new protocol mimicking the spider's spinning process is developed to create highly oriented microfibers from graphene-based composite via a purpose-designed microfluidic chip...
March 7, 2018: ACS Applied Materials & Interfaces
Qing-Qing Jiang, Ning Yu, Shi-Ming Yang
BACKGROUND: Noise exposure can lead to hearing loss and multiple system dysfunctions. As various forms of noise exist in our living environments, and our auditory organs are very sensitive to acoustic stimuli, it is a challenge to protect our hearing system in certain noisy environments. PRESENTATION OF THE HYPOTHESIS: Herein, we propose that our hearing organ could serve as a noise eliminator for high intensity noise and enhance acoustic signal processing abilities by increasing the signal-noise ratio...
February 26, 2018: Military Medical Research
Timothy B Esler, Robert R Kerr, Bahman Tahayori, David B Grayden, Hamish Meffin, Anthony N Burkitt
Currently, a challenge in electrical stimulation of the retina with a visual prosthesis (bionic eye) is to excite only the cells lying directly under the electrode in the ganglion cell layer, while avoiding excitation of axon bundles that pass over the surface of the retina in the nerve fiber layer. Stimulation of overlying axons results in irregular visual percepts, limiting perceptual efficacy. This research explores how differences in fiber orientation between the nerve fiber layer and ganglion cell layer leads to differences in the electrical activation of the axon initial segment and axons of passage...
2018: PloS One
Ranu Jung, James J Abbas, Sathyakumar Kuntaegowdanahalli, Anil K Thota
The network of peripheral nerves presents extraordinary potential for modulating and/or monitoring the functioning of internal organs or the brain. The degree to which these pathways can be used to influence or observe neural activity patterns will depend greatly on the quality and specificity of the bionic interface. The anatomical organization, which consists of multiple nerve fibers clustered into fascicles within a nerve bundle, presents opportunities and challenges that may necessitate insertion of electrodes into individual fascicles to achieve the specificity that may be required for many clinical applications...
January 2018: Bioelectron Med (Lond)
Liping Sun, Yong Zhong, Jie Gui, Xianwu Wang, Xiaorong Zhuang, Jian Weng
Background: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive and memory impairment. It is the most common neurological disease that causes dementia. Soluble amyloid-beta oligomers (AβO) in blood or cerebrospinal fluid (CSF) are the pathogenic biomarker correlated with AD. Methods: A simple electrochemical biosensor using graphene oxide/gold nanoparticles (GNPs) hydrogel electrode was developed in this study. Thiolated cellular prion protein (PrPC ) peptide probe was immobilized on GNPs of the hydrogel electrode to construct an AβO biosensor...
2018: International Journal of Nanomedicine
Farzaneh Ahmadi, Farzad Noorian, Daniel Novakovic, André van Schaik
Despite emergent progress in many fields of bionics, a functional Bionic Voice prosthesis for laryngectomy patients (larynx amputees) has not yet been achieved, leading to a lifetime of vocal disability for these patients. This study introduces a novel framework of Pneumatic Bionic Voice Prostheses as an electronic adaptation of the Pneumatic Artificial Larynx (PAL) device. The PAL is a non-invasive mechanical voice source, driven exclusively by respiration with an exceptionally high voice quality, comparable to the existing gold standard of Tracheoesophageal (TE) voice prosthesis...
2018: PloS One
Yuanyuan Xu, Xiao Guo, Shuaitao Yang, Long Li, Peng Zhang, Wei Sun, Changyong Liu, Shengli Mi
Articular cartilage (AC) has gradient features in both mechanics and histology as well as a poor regeneration ability. The repair of AC poses difficulties in both research and the clinic. In this paper, a gradient scaffold based on PLGA-ECM was proposed. Cartilage scaffolds with a three-layer gradient structure were fabricated by PLGA through 3D printing, and the microstructure orientation and pore fabrication were made by dECM injection and directional freezing. The manufactured scaffold has a mechanical strength close to that of real cartilage...
February 20, 2018: Journal of Biomedical Materials Research. Part A
Kejing Zhang, Mengying Si, Dan Liu, Shengnan Zhuo, Mingren Liu, Hui Liu, Xu Yan, Yan Shi
Background: The recalcitrance of lignocellulosic biomass offers a series of challenges for biochemical processing into biofuels and bio-products. For the first time, we address these challenges with a biomimetic system via a mild yet rapid Fenton reaction and lignocellulose-degrading bacterial strain Cupriavidus basilensis B-8 (here after B-8) to pretreat the rice straw (RS) by mimicking the natural fungal invasion process. Here, we also elaborated the mechanism through conducting a systematic study of physicochemical changes before and after pretreatment...
2018: Biotechnology for Biofuels
Qingwei Li, Changhong Liu, Shoushan Fan
The electro-active polymer (EAP) actuators, such as electronic, ionic and electrothermal (ET) actuators, have become the important branch of next-generation soft actuators in bionic robotics. However, most reported EAP actuators could only realize simple movements which are restricted by the small area of flexible electrodes and simple designs. Herein, we prepared large-area flexible electrodes with high anisotropy made of oriented carbon nanotube (CNT) paper, and carried out artful graphic designs and processing on the electrodes to make functional ET bimorph actuators which can realize large bending deformations (over 220°, curvature > 1...
February 13, 2018: Nanotechnology
Alicia Londono, Ryan Wallace, Zheala Qayyum
No abstract text is available yet for this article.
January 29, 2018: Translational Behavioral Medicine
Aaron Trinidade, Matthew D Cox, Amro Hassaan, Connor Rayburn, John L Dornhoffer
Patients and parents in particular can find the decision regarding which device to have implanted difficult due to the amount of often complicated information that is available. The desire to choose the 'right' implant for themselves or their child takes on great importance due to the finality of the procedure. There is some evidence that certain patient expectations may be linked to brand choice and marketing strategies. This study showed that importance of language development was strongly linked with a MED-EL device, and speech improvement with Advanced Bionics...
January 30, 2018: Clinical Otolaryngology
Peng Hao, Jianxun Du
Beetles have developed the elytra that are interesting and impressive strategy for thriving in their native environments. The elytra, although formed from simple biopolymer constituents, take on many effective designs. In present work, internal structure of elytra is discussed and three bionic structures named as the bio-inspired honeycomb column thin-walled structure (BHTS) are proposed. Then the crushing behavior and energy absorption characteristics of the BHTS under axial impact loading are investigated by numerical simulation...
January 4, 2018: Journal of the Mechanical Behavior of Biomedical Materials
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