Ping Zhang, Nopphon Weeranoppanant, Dale A Thomas, Kohei Tahara, Torsten Stelzer, Mary Grace Russell, Marcus O'Mahony, Allan S Myerson, Hongkun Lin, Liam P Kelly, Klavs F Jensen, Timothy F Jamison, Chunhui Dai, Yuqing Cui, Naomi Briggs, Rachel L Beingessner, Andrea Adamo
As a demonstration of an alternative to the challenges faced with batch pharmaceutical manufacturing including the large production footprint and lengthy time-scale, we previously reported a refrigerator-sized continuous flow system for the on-demand production of essential medicines. Building on this technology, herein we report a second-generation, reconfigurable and 25 % smaller (by volume) continuous flow pharmaceutical manufacturing platform featuring advances in reaction and purification equipment. Consisting of two compact [0...
January 31, 2018: Chemistry: a European Journal