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Renal calculi

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https://www.readbyqxmd.com/read/29750296/hyperoside-protects-human-kidney%C3%A2-2-cells-against-oxidative-damage-induced-by-oxalic-acid
#1
Yongliang Chen, Lihong Ye, Wangjian Li, Dongzhang Li, Feng Li
The majority of renal calculi (kidney stones) are calcium stones. Oxidative damage to renal tubular epithelial cells induced by reactive oxygen species (ROS) is the predominant cause of calcium oxalate stone formation. Hyperoside (Hyp) is a flavonol glycoside extracted from medicinal plants and appears to exhibit potent antioxidant activity in various cells. The aim of the present study was to investigate the protective effect of Hyp on renal cells exposed to oxidative stress simulated by oxalic acid (OA), and to determine whether the underlying mechanism involves the nuclear factor E2‑related factor2 (Nrf2)‑antioxidative response element signaling pathway...
May 2, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29732915/retrograde-ureteroscopic-management-of-large-renal-calculi-a-single-institutional-experience-and-concise-literature-review
#2
Kymora Scotland, Benjamin Rudnick, Kelly A Healy, Scott G Hubosky, Demetrius Bagley
INTRODUCTION: Advances in flexible ureteroscope design and accessory instrumentation have allowed for more challenging cases to be treated ureteroscopically. Here we evaluate our experience with ureteroscopy for the management of large renal calculi (≥ 2cm) and provide a concise review of recent reports.. METHODS: A retrospective review was undertaken of all ureteroscopy cases between 2004 and 2014 performed by the endourologic team at a single academic tertiary care institution...
May 5, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29719337/the-impact-of-stone-composition-on-renal-function
#3
Anmar Nassir, Hesham Saada, Taghreed Alnajjar, Jomanah Nasser, Waed Jameel, Soha Elmorsy, Hattan Badr
Background: Nephrolithiasis is a common condition that has various classifications according to stone composition. Stone formation can affect renal function; it can be a strong risk factor for chronic kidney disease (CKD). The main objective of this study is to explore the association between creatinine clearance and different stone compositions. Methods: This is a retrospective cohort study conducted in a tertiary center in Jeddah, Saudi Arabia, between 2005 and 2014...
April 2018: Urology Annals
https://www.readbyqxmd.com/read/29719328/miniaturized-percutaneous-nephrolithotomy-versus-retrograde-intrarenal-surgery-in-the-treatment-of-renal-stones-with-a-diameter-15-mm-a-3-year-open-label-prospective-study
#4
Sunil Mhaske, Mehul Singh, Abhirudra Mulay, Sharadkumar Kankalia, Vikram Satav, Vilas Sabale
Aim: The aim of this study is to compare the outcomes of miniaturized percutaneous nephrolithotomy (mini-perc) and retrograde intrarenal surgery (RIRS) in management of renal stones with a diameter <15 mm. Materials and Methods: This was an open-label prospective study that included a total of 80 cases underwent mini-perc ( n = 40) and RIRS ( n = 40) between July 2014 and August 2017. The primary outcome objective was stone-free rate, retreatment rate, complications, hospital stay, operative time, and reduction in hemoglobin level...
April 2018: Urology Annals
https://www.readbyqxmd.com/read/29705963/metabolite-diagnosis-of-primary-hyperoxaluria-type-3
#5
Lawrence Greed, Frank Willis, Lilian Johnstone, Sharon Teo, Ruth Belostotsky, Yaacov Frishberg, James Pitt
BACKGROUND: Primary hyperoxaluria type 3 (PH3) is a recently described cause of childhood renal calculi. It results from mutations in the HOGA1 gene and most cases have been diagnosed after clinical ascertainment, exclusion of other genetic hyperoxalurias and mutation testing. Metabolite testing has not been widely applied but holds promise for the rapid screening and diagnosis of patients who are not specifically suspected to have PH3. CASE-DIAGNOSIS/TREATMENT: Two cases presented with renal calculi...
April 28, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29705059/-result-of-treatment-of-urinary-lithiasis-for-professional-aptitude
#6
C Julien, J Laroche, F-X Deledalle, F-X Brocq, R Fournier, P Rivière, E Lechevallier, P-H Savoie
INTRODUCTION: Military people are inapt for presence of urinary stones. In this specific population, the treatment of stones is even more aggressive than for the general population without recommendation. The final decision about aptitude is the responsibility of the military doctor. Whereas, ureteroscopy has its place there and must done by any urologist. METHODS: The purpose of this study was to estimate the results of treatments by ureteroscopy in this population...
April 25, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29702097/can-renal-and-bladder-ultrasound-replace-ct-urogram-in-patients-investigated-for-microscopic-hematuria
#7
Wei Shen Tan, Rachael Sarpong, Pramit Khetrapal, Simon Rodney, Hugh Mostafid, Joanne Cresswell, James Hicks, Abhay Rane, Alastair Henderson, Dawn Watson, Jacob Cherian, Norman Williams, Chris Brew-Graves, Andrew Feber, John D Kelly
PURPOSE: Computed tomography urogram (CTU) is recommended when investigating patients with hematuria. We determine the incidence of urinary tract cancer and compare the diagnostic accuracy of CTU and renal and bladder ultrasound (RBUS) at identifying urinary tract cancer. METHODS: The DETECT I study (clinicaltrials.gov NCT02676180) is a prospective observational study recruiting patients ≥18 years following a presentation of macroscopic or microscopic haematuria at 40 hospitals...
April 24, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29684972/-pyeloduodenal-fistula-caused-by-renal-calculi
#8
Byeong Kyu Park, Gwang Ha Kim
A fistula between the renal pelvis and duodenum (pyeloduodenal fistula) is very rare. It can occur spontaneously or after trauma to one of these organs. A spontaneous pyeloduodenal fistula is usually caused by chronic inflammation, including reactions to foreign bodies, nephrolithiasis, benign and malignant neoplasms, as well as pyogenic infections. The main treatment to date has been surgery. We encountered one case of pyeloduodenal fistula found during an evaluation for abdominal discomfort in a 39-year-old female...
April 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29676347/dual-energy-computed-tomography-a-reliable-and-established-tool-for-in-vivo-differentiation-of-uric-acid-from-nonuric-acid-renal-stones
#9
Mohd Ilyas, Ghanshyam Dev, Anchal Gupta, Tameem Ahmad Bhat, Shwait Sharma
Background: Dual-energy computed tomography (DECT) utilises the technique of simultaneous image acquisition of a body part at two different energy levels of the X-ray tubes. We used the DECT in this project to study its accuracy in non-invasive in vivo differentiation of uric acid (UA) calculi from non-UA calculi using the 3rd generation dual-source computed tomography (CT) scanner. Materials and Methods: The DECT ratios of the various stones were noted and compared with the postextraction analysis of stones for composition...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29675722/contrast-enhanced-or-noncontrast-ct-for-renal-colic-utilizing-urinalysis-and-patient-history-of-urolithiasis-to-decide
#10
Vishal Desai, Mougnyan Cox, Sandeep Deshmukh, Christopher G Roth
PURPOSE: In the emergency setting, flank pain commonly leads to a noncontrast CT despite a significant percentage of patients having alternative diagnoses, often difficult to characterize without contrast. We investigated the combined utility of urinalysis and history of urolithiasis in identifying patients who are unlikely to have urolithiasis and may benefit from a contrast-enhanced study. METHODS: Retrospective review of 350 patients from May 2013 to May 2016 was performed for patients in the emergency department with renal colic that underwent noncontrast CT and urinalysis testing...
April 20, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29672249/urinary-tract-infection-by-strongyloides-stercoralis-a-case-report
#11
Nilo Manoel Pereira Vieira Barreto, Joelma Nascimento de Souza, Weslei Almeida Costa Araujo, Nadia Andrade Khouri, Ernesto Pereira de Oliveira, Márcia Cristina Aquino Teixeira, Neci Matos Soares
The objective of this study was to report a case of a hydronephrotic patient with Strongyloides stercoralis infection, with discharge of rhabditoid larva exclusively in urine. In 2013, a 72-yr-old, male patient, hypertensive, obese and diagnosed with hydronephrosis secondary to renal calculi, reported lumbar pain, polyuria, polaciuria and dysuria, as well as frequent urinary tract infections. The microscopic analysis of urine sediment showed the presence of S. stercoralis rabditoid larva. However, parasitological examinations by Baermann-Moraes, agar plate culture and spontaneous sedimentation, performed with 3 fecal samples on alternate days had negative results...
April 19, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29668355/a-prospective-comparative-study-of-continuous-and-interrupted-suturing-in-laparoscopic-pyeloplasty-in-3d-era
#12
Manickam Ramalingam, Senthil Kallappan, Sivasankaran Nachimuthu
INTRODUCTION: Laparoscopic pyeloplasty is becoming the gold standard procedure for pelviureteric junction obstruction. The outcome of pyeloplasty depends on precise pyeloureteral anastomosis. Though in open pyeloplasty interrupted or continuous suture are practiced, in most of the laparoscopic or laparoscopy-assisted robotic pyeloplasty continuous suturing is practiced. After acquiring a 3-dimensional (3D) camera, we prospectively analyzed the suturing time, complication rate, and success rate between interrupted and continuous suturing in laparoscopic pyeloplasty...
April 18, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29666742/focal-xanthogranulomatous-pyelonephritis-with-pulmonary-lesions-on-the-background-of-type-two-diabetes-mellitus
#13
Ahmad Enshaei, Arash A Boora, Diana Taheri, Zahra Changizi, Nahid Bahmani
Focal Xanthogranulomatous pyelonephritis is a rare chronic inflammatory condition of kidneys which usually is associated with postrenal obstruction or renal stone leading to chronic bacterial infection and eventually chronic glomerular inflammation. About 90% of cases are of the diffuse type and associated with staghorn renal calculi. The case presented in this paper is of the focal type in a 58-year-old diabetic female. Interestingly she did not have symptoms or laboratory presentation of chronic renal bacterial infection except for elevated ESR...
2018: Case Reports in Radiology
https://www.readbyqxmd.com/read/29660680/phase-composition-and-morphological-characterization-of-human-kidney-stones-using-ir-spectroscopy-scanning-electron-microscopy-and-x-ray-rietveld-analysis
#14
Paramita Chatterjee, Arup Chakraborty, Alok K Mukherjee
Pathological calcification in human urinary tract (kidney stones) is a common problem affecting an increasing number of people around the world. Analysis of such minerals or compounds is of fundamental importance for understanding their etiology and for the development of prophylactic measures. In the present study, structural characterization, phase quantification and morphological behaviour of thirty three (33) human kidney stones from eastern India have been carried out using IR spectroscopy (FT-IR), powder X-ray diffraction (PXRD) and scanning electron microscopy (SEM)...
April 9, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29649833/suctioning-minimally-invasive-percutaneous-nephrolithotomy-with-a-patented-system-is-effective-to-treat-renal-staghorn-calculi-a-prospective-multicenter-study
#15
Chuance Du, Leming Song, Xiaoyuan Wu, Difu Fan, Lunfeng Zhu, Shengfeng Liu, Xiaolin Deng, Tairong Liu, Zhongsheng Yang, Zuofeng Peng, Min Hu, Qigui Liu, Tiejun Pan, Zhiqiang Chen, Zhangqun Ye
OBJECTIVES: To investigate the safety, efficacy, and practicability of minimally invasive percutaneous nephrolithotomy (MPCNL) with the aid of a patented irrigation clearance system in treating renal staghorn calculi. METHODS: From August 2009 to July 2014, 4 hospitals had executed a prospective multicenter study with a total of 912 cases. The patients were randomly divided into 3 groups: suctioning MPCNL, standard percutaneous nephrolithotomy (PCNL), and traditional MPCNL groups...
April 12, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29643889/therapeutic-effects-of-visual-standard-channel-combined-with-f4-8-visual-puncture-super-mini-percutaneous-nephrolithotomy-on-multiple-renal-calculi
#16
Zhenyu Cui, Yanjun Gao, Wenzeng Yang, Chunli Zhao, Tao Ma, Xiaoqiang Shi
Objective: To evaluate the therapeutic effects of visual standard channel combined with F4.8 visual puncture super-mini percutaneous nephrolithotomy (SMP) on multiple renal calculi. Methods: The clinical data of 46 patients with multiple renal calculi treated in Affiliated Hospital of Hebei University from October 2015 to September 2016 were retrospectively analyzed. There were 28 males and 18 females aged from 25 to 65 years old, with an average of 42.6. The stone diameters were 3...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29629868/computed-tomography-identified-factors-that-preclude-living-kidney-donation
#17
Katerina Mastrocostas, Christina M Chingkoe, Kenneth T Pace, Joseph J Barfett, Anish Kirpalani, Gevork N Mnatzakanian, Paraskevi A Vlachou, Errol Colak
INTRODUCTION: The purpose of this study was to determine the variety and prevalence of renal and non-renal abnormalities detected on multi-detector computed tomography (MDCT) that precluded patients from donating a kidney. METHODS: Institutional review board approval was obtained and the requirement for informed consent was waived. A retrospective, single-centre review of 701 patients (444 female, 257 male; age range 18-86 years; mean age 43.2±11.9 years) that underwent renal donor protocol MDCT was conducted...
April 6, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29626256/dual-layer-spectral-detector-ct-non-inferiority-assessment-compared-to-dual-source-dual-energy-ct-in-discriminating-uric-acid-from-non-uric-acid-renal-stones-ex-vivo
#18
Lakshmi Ananthakrishnan, Xinhui Duan, Yin Xi, Matthew A Lewis, Margaret S Pearle, Jodi A Antonelli, Harold Goerne, Elysha M Kolitz, Suhny Abbara, Robert E Lenkinski, Julia R Fielding, John R Leyendecker
PURPOSE: To assess the non-inferiority of dual-layer spectral detector CT (SDCT) compared to dual-source dual-energy CT (dsDECT) in discriminating uric acid (UA) from non-UA stones. METHODS: Fifty-seven extracted urinary calculi were placed in a cylindrical phantom in a water bath and scanned on a SDCT scanner (IQon, Philips Healthcare) and second- and third-generation dsDECT scanners (Somatom Flash and Force, Siemens Healthcare) under matched scan parameters. For SDCT data, conventional images and virtual monoenergetic reconstructions were created...
April 7, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29625868/combined-use-of-flexible-ureteroscopic-lithotripsy-with-micro-percutaneous-nephrolithotomy-in-pediatric-multiple-kidney-stones
#19
Jun Li, Wenying Wang, Yuan Du, Ye Tian
BACKGROUND: We investigated the clinical value of treating pediatric multiple kidney stones with extensive distribution using flexible ureteroscopic lithotripsy (FUL) combined with micro-percutaneous nephrolithotomy (micro-PNL). PATIENTS AND METHODS: In total, 21 pediatric patients with multiple renal calculi between May 2016 and June 2017 received FUL combined with micro-PNL. The group included 13 boys and eight girls; the patients' mean age was 3.8 years (range 1-8 years)...
March 28, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29625137/sensitivity-of-non-contrast-computed-tomography-for-small-renal-calculi-with-endoscopy-as-the-gold-standard
#20
Naeem Bhojani, Jessica E Paonessa, Marawan M El Tayeb, James C Williams, Tariq A Hameed, James E Lingeman
OBJECTIVES: To compare the sensitivity of non-contrast CT to endoscopy for detection of renal calculi. Imaging modalities for detection of nephrolithiasis have centered on abdominal x-ray (KUB), ultrasound (US), and non-contrast computed tomography (CT). Sensitivities of 58-62% (KUB), 45% (US), and 95-100% (CT) have been previously reported. However, these results have never been correlated with endoscopic findings. METHODS: Idiopathic calcium oxalate stone formers with symptomatic calculi requiring ureteroscopy (URS) were studied...
April 3, 2018: Urology
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