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Prostate cancer gamma knife

Z Huang, Y Feng, S Lo, J Grecula, N Mayr, W Yuh
PURPOSE: The dose-volume histogram (DVH) has been normally accepted as a tool for treatment plan evaluation. However, spatial information is lacking in DVH. As a supplement to the DVH in three-dimensional treatment planning, the differential DVH (DDVH) provides the spatial variation, the size and magnitude of the different dose regions within a region of interest, which can be incorporated into tumor control probability model. This study was to provide a method in evaluating and improving Gamma Knife treatment planning...
June 2015: Medical Physics
Y Feng, Z Huang, S Lo, N Mayr, W Yuh
PURPOSE: To improve Gamma Knife SRS treatment efficiency for brain metastases and compare the differences of treatment time and radiobiological effects between two different planning methods of automatic filling and manual placement of shots with inverse planning. METHODS: T1-weighted MRI images with gadolinium contrast from five patients with a single brain metastatic-lesion were used in this retrospective study. Among them, two were from primary breast cancer, two from primary melanoma cancer and one from primary prostate cancer...
June 2015: Medical Physics
Adela Poitevin-Chacón, José Hinojosa-Gómez
AIM: This survey is performed to learn about the structure of radiotherapy in México. BACKGROUND: Radiation oncology practice is increasing because of the higher incidence of cancer. There is no published data about radiotherapy in México. MATERIALS AND METHODS: A questionnaire was sent to the 83 registered centers in the database of the Mexican regulatory agency. One out of the 32 states has no radiotherapy. 27 centers from 14 states provided their answers...
2012: Reports of Practical Oncology and Radiotherapy
Joshua Y Menendez, David F Bauer, Chevis N Shannon, John Fiveash, James M Markert
We evaluated the local control of gamma knife stereotactic radiosurgery (GKSRS) in the treatment of cerebral metastases from primary tumors that rarely metastasize to the central nervous system (CNS). There is little published data on this subject with very few series on specific primary tumors. We present our experience treating these lesions with GKSRS combined with a review of the salient literature. A retrospective study of 36 patients who collectively underwent 44 GKSRS procedures for CNS metastatic disease was undertaken...
September 2012: Journal of Neuro-oncology
Teruki Teshima, Hodaka Numasaki, Masamichi Nishio, Hiroshi Ikeda, Kenji Sekiguchi, Norihiko Kamikonya, Masahiko Koizumi, Masao Tago, Yutaka Ando, Nobuhito Tsukamoto, Atsuro Terahara, Katsumasa Nakamura, Masao Murakami, Mitsuhiro Takahashi, Tetsuo Nishimura
The ongoing structure of radiation oncology in Japan in terms of equipment, personnel, patient load and geographic distribution was evaluated in order to radiation identify and improve any deficiencies. A questionnaire-based national structure survey was conducted from March 2010 to January 2011 by the Japanese Society for Therapeutic Radiology and Oncology (JASTRO). These data were analyzed in terms of the institutional stratification of the Patterns of Care Study (PCS). The total numbers of new cancer patients and total of cancer patients (new and repeat) treated with radiation in 2009 were estimated at 201,000 and 240,000, respectively...
September 2012: Journal of Radiation Research
Douglas Kondziolka, Ajay Niranjan, Hideyuki Kano, John C Flickinger, L Dade Lunsford
We evaluated the role of Gamma Knife stereotactic radiosurgery in the multidisciplinary management of brain metastases ovarian and endometrial, prostate, thyroid, sarcoma, or unknown primary cancers. From a series of over 3,000 patients who had Gamma Knife radiosurgery for brain metastases we reviewed indications and outcomes in patients with less common cancer types. All tumor types responded favorably to radiosurgery. Patients with male and female genitourinary primaries tended to develop brain metastases late in their course and did worse...
2012: Progress in Neurological Surgery
Tomas Dvorak, David E Wazer
PURPOSE: Proton therapy is an increasingly prominent radiation treatment modality. Market-driven adoption of proton therapy into routine clinical practice may have a significant economic impact. The aim of this study was to estimate the proportion of patients who could potentially be treated with proton therapy by evaluating the utilization of existing highly conformal photon therapy as a proxy. METHODS: All patients treated in 2007 with radiation therapy at the authors' institution were evaluated...
July 2010: Journal of the American College of Radiology: JACR
Teruki Teshima, Hodaka Numasaki, Hitoshi Shibuya, Masamichi Nishio, Hiroshi Ikeda, Kenji Sekiguchi, Norihiko Kamikonya, Masahiko Koizumi, Masao Tago, Yutaka Ando, Nobuhito Tsukamoto, Atsuro Terahara, Katsumasa Nakamura, Michihide Mitsumori, Tetsuo Nishimura, Masato Hareyama et al.
PURPOSE: To evaluate the ongoing structure of radiation oncology in Japan in terms of equipment, personnel, patient load, and geographic distribution to identify and improve any deficiencies. METHODS AND MATERIALS: A questionnaire-based national structure survey was conducted from March to December 2008 by the Japanese Society of Therapeutic Radiology and Oncology (JASTRO). These data were analyzed in terms of the institutional stratification of the Patterns of Care Study...
December 1, 2010: International Journal of Radiation Oncology, Biology, Physics
Sonia Maciá Escalante, Carmen Guillén Ponce, Maria José Molina Garrido, Maria José Martínez Ortiz, Inmaculada Ballester Navarro, Alfredo Carrato Mena
Prognosis in prostate cancer is determined, in greater part, by the presence of metastases. Bone metastases can occur in any part of the skeleton even, for example, at the base of the skull. We present a case of a 78 year old male who, in December 2001, presented with paralysis of the third cranial nerve. The NMR and CAT scans were normal and circulating levels of PSA were elevated. He was referred to the Urology Service where the treatment guidelines included complete androgen block. Subsequently, he developed retro-orbital pain, divergent strabismus and palpebral ptosis...
October 2005: Clinical & Translational Oncology
Motohiro Hayashi, Takaomi Taira, Mikhail Chernov, Masahiro Izawa, Roman Liscak, Chung Ping Yu, Robert T K Ho, Yoko Katayama, Nobuo Kouyama, Yoriko Kawakami, Tomokatsu Hori, Kintomo Takakura
RATIONALE: Two or three decades ago, cancer pain was treated by surgical/chemical hypophysectomy. In one report, the control of central pain (thalamic pain syndrome) was also approached with chemical hypophysectomy. Although in most of the patients these treatments resulted in a decrease in severe pain, concomitantly severe adverse effects (panhypopituitarism, diabetes insipidus and visual dysfunction) occurred in most patients. This historical evidence prompted us to perform Gamma Knife surgery (GKS) for this kind of intractable severe pain using a high irradiation dose to the pituitary stalk/gland...
2003: Stereotactic and Functional Neurosurgery
Motohiro Hayashi, Takaomi Taira, Mikhail Chernov, Seji Fukuoka, Roman Liscak, Chung Ping Yu, Robert T K Ho, Jean Regis, Yoko Katayama, Yoriko Kawakami, Tomokatsu Hori
OBJECT: The authors have treated intractable pain, particularly cancer pain related to bone metastasis, with various protocols. Cancer pain has been treated by gamma knife radiosurgery (GKS), targeted to the pituitary gland-stalk, as an alternative new pain control method. The purpose of this study was to investigate a prospective multicenter protocol to prove the efficacy and the safety of this treatment. METHODS: Indications for patient inclusion in this treatment protocol were: 1) pain related to bone metastasis; 2) no other effective pain treatment options; 3) general condition rated as greater than 40 on the Kamofsky Performance Scale; 4) morphine effective for pain control; and 5) no previous treatment with radiation (GKS or conventional radiotherapy) for brain metastasis...
December 2002: Journal of Neurosurgery
H Minami, K Kanagawa, Y Watanabe, T Sakakura, T Ito, M Kawamura, T Nakatani, T Kishimoto
A 59-year-old male visited us with a chief complaint of dysuria. The serum prostate specific antigen (PSA) level was within normal limits, and intravenous pyelography and urethrocystography showed no abnormal findings. Because of his urinary retention, transurethral resection of prostate was performed under a clinical diagnosis of benign prostatic hyperplasia. The pathological diagnosis was poorly differentiated adenocarcinoma of the prostate. Not only combination hormone therapy with goserelin acetate and flutamide, but also intermittent arterial infusion chemotherapy with cisplatin (CDDP) and pirarubicin (THP) using a reservoir system was administered...
May 2001: Hinyokika Kiyo. Acta Urologica Japonica
V M Riccardi
If there is any one thing that is missing in today's health care delivery system, it is consumerism. This will be remedied as more and more Americans start taking direct responsibility for how their health care dollars are spent. Hand in hand with such developments will be increasing opportunities for developers and sellers of health-related products and services to promote their wares directly to medical consumers, who will either buy them outright or influence their healthplans to make the purchases. Purveyors of new technology and capital medical equipment will be especially likely to abet the new medical consumers and to derive financial benefits from them...
November 1998: Administrative Radiology Journal: AR
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